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bupropion and Acute Liver Injury, Drug-Induced

bupropion has been researched along with Acute Liver Injury, Drug-Induced in 15 studies

Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.

Research Excerpts

ExcerptRelevanceReference
"Bupropion is an antidepressant that is also used as a non-nicotine method to aid in smoking cessation."3.88Rapid bupropion-induced hepatotoxicity: a case report and review of the literature. ( Anandabaskaran, S; Ho, V, 2018)
"Bupropion was included as structurally related drug used therapeutically."1.46Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones. ( Krähenbühl, S; Liechti, ME; Luethi, D, 2017)
" We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts."1.37FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's1 (6.67)18.2507
2000's5 (33.33)29.6817
2010's8 (53.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Chen, M2
Vijay, V1
Shi, Q2
Liu, Z3
Fang, H2
Tong, W3
Ding, D1
Kelly, R1
Warner, DJ1
Chen, H1
Cantin, LD1
Kenna, JG1
Stahl, S1
Walker, CL1
Noeske, T1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
Luethi, D1
Liechti, ME1
Krähenbühl, S1
Anandabaskaran, S1
Ho, V1
Lin, K1
Zhang, Q1
Yang, S1
Lin, Y1
Wen, C1
Zheng, Y1
Carlos Titos-Arcos, J1
Hallal, H1
Collados, V1
Plaza-Aniorte, J1
Silva, RR1
Tucker, WE1
Oslin, DW1
Duffy, K1
Hu, KQ1
Tiyyagura, L1
Kanel, G1
Redeker, AG1
Alvaro, D1
Onetti-Muda, A1
Moscatelli, R1
Atili, AF1

Reviews

1 review available for bupropion and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016

Other Studies

14 other studies available for bupropion and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012
Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones.
    Toxicology, 2017, 07-15, Volume: 387

    Topics: Adenosine Triphosphate; Alkaloids; Benzodioxoles; Bupropion; Chemical and Drug Induced Liver Injury;

2017
Rapid bupropion-induced hepatotoxicity: a case report and review of the literature.
    Journal of medical case reports, 2018, Feb-24, Volume: 12, Issue:1

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Chemical and Drug Induced Liver Injury; Female;

2018
Effects of suberoylanilide hydroxamic acid on rat cytochrome P450 enzyme activities.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:5

    Topics: Administration, Oral; Animals; Bupropion; Chemical and Drug Induced Liver Injury; Chromatography, Li

2015
[Acute hepatitis secondary to bupropion].
    Gastroenterologia y hepatologia, 2008, Volume: 31, Issue:8

    Topics: Acute Disease; Antidepressive Agents, Second-Generation; Bupropion; Chemical and Drug Induced Liver

2008
Two recent updates for psychiatric conditions.
    Journal of child and adolescent psychopharmacology, 2009, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Atomoxetine Hydrochloride; Benzazepines; Bupropion; Chem

2009
Adverse drug reaction update.
    Adverse drug reactions and toxicological reviews, 2002, Volume: 21, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bupropion; Chemical and Drug Induced Liver Injury;

2002
Preclinical toxicology of bupropion: an overview.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5 Pt 2

    Topics: Abnormalities, Drug-Induced; Animals; Antidepressive Agents; Bupropion; Central Nervous System; Chem

1983
The rise of serum aminotransferases in a patient treated with bupropion.
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:5

    Topics: Aged; Alanine Transaminase; Aspartate Aminotransferases; Bipolar Disorder; Bupropion; Chemical and D

1993
Acute hepatitis induced by bupropion.
    Digestive diseases and sciences, 2000, Volume: 45, Issue:9

    Topics: Acute Disease; Adult; Antidepressive Agents, Second-Generation; Bupropion; Chemical and Drug Induced

2000
Acute cholestatic hepatitis induced by bupropion prescribed as pharmacological support to stop smoking. A case report.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2001, Volume: 33, Issue:8

    Topics: Acute Disease; Antidepressive Agents, Second-Generation; Bupropion; Chemical and Drug Induced Liver

2001