Page last updated: 2024-10-17

bupropion and Abnormality, Heart

bupropion has been researched along with Abnormality, Heart in 5 studies

Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.

Research Excerpts

ExcerptRelevanceReference
"Reports from the GlaxoSmithKline Bupropion Pregnancy Registry suggested an increase in cardiovascular defects following exposure to bupropion during pregnancy."7.74Bupropion in pregnancy and the prevalence of congenital malformations. ( Cole, JA; Cosmatos, IS; Haight, BR; Modell, JG; Stoler, JM; Walker, AM, 2007)
"(3) An increased risk of birth defects, particularly cardiac malformations, is also suspected after exposure to amphetamine derivatives during pregnancy."5.33Bupropion (amfebutamone): caution during pregnancy. ( , 2005)
" Exposure categories included first-trimester bupropion alone or in combination with other antidepressants, first-trimester antidepressants other than bupropion, and no exposure to any antidepressant at any time from 2 months prior to pregnancy through delivery."3.80First-trimester exposure to bupropion and risk of cardiac malformations. ( Kerr, S; Louik, C; Mitchell, AA, 2014)
"Bupropion, an amphetamine, is authorised as an aid to smoking cessation, despite its negative harm-benefit balance."3.78Bupropion: congenital heart defects (continued). ( , 2012)
"We sought to determine if maternal bupropion treatment in early pregnancy is associated with congenital heart defects in the infant."3.76Maternal use of bupropion and risk for congenital heart defects. ( Alwan, S; Botto, LD; Correa, A; Friedman, JM; Rasmussen, SA; Reefhuis, J, 2010)
"Reports from the GlaxoSmithKline Bupropion Pregnancy Registry suggested an increase in cardiovascular defects following exposure to bupropion during pregnancy."3.74Bupropion in pregnancy and the prevalence of congenital malformations. ( Cole, JA; Cosmatos, IS; Haight, BR; Modell, JG; Stoler, JM; Walker, AM, 2007)
"(3) An increased risk of birth defects, particularly cardiac malformations, is also suspected after exposure to amphetamine derivatives during pregnancy."1.33Bupropion (amfebutamone): caution during pregnancy. ( , 2005)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Louik, C1
Kerr, S1
Mitchell, AA1
Alwan, S1
Reefhuis, J1
Botto, LD1
Rasmussen, SA1
Correa, A1
Friedman, JM1
Cole, JA1
Modell, JG1
Haight, BR1
Cosmatos, IS1
Stoler, JM1
Walker, AM1

Other Studies

5 other studies available for bupropion and Abnormality, Heart

ArticleYear
First-trimester exposure to bupropion and risk of cardiac malformations.
    Pharmacoepidemiology and drug safety, 2014, Volume: 23, Issue:10

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Antidepressive Agents, Second-Generation; Bupropion;

2014
Maternal use of bupropion and risk for congenital heart defects.
    American journal of obstetrics and gynecology, 2010, Volume: 203, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Case-Control Studies; Chi-Square Distrib

2010
Bupropion: congenital heart defects (continued).
    Prescrire international, 2012, Volume: 21, Issue:126

    Topics: Bupropion; Dopamine Uptake Inhibitors; Drug Monitoring; Female; Heart Defects, Congenital; Humans; I

2012
Bupropion (amfebutamone): caution during pregnancy.
    Prescrire international, 2005, Volume: 14, Issue:80

    Topics: Amphetamines; Antidepressive Agents, Second-Generation; Bupropion; Congenital Abnormalities; Contrai

2005
Bupropion in pregnancy and the prevalence of congenital malformations.
    Pharmacoepidemiology and drug safety, 2007, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Bupropion; Congenital Abnormalities; Da

2007