Page last updated: 2024-10-24

bupivacaine and Uterine Neoplasms

bupivacaine has been researched along with Uterine Neoplasms in 8 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Uterine Neoplasms: Tumors or cancer of the UTERUS.

Research Excerpts

ExcerptRelevanceReference
"Sixty premenopausal women with uterine leiomyomata were enrolled in a randomized controlled design and intraoperatively treated with injection of bupivacaine plus epinephrine (group A) or saline solution (group B) during laparoscopic myomectomy."5.11Bupivacaine plus epinephrine for laparoscopic myomectomy: a randomized placebo-controlled trial. ( Barletta, E; Corea, D; Doldo, P; Falbo, A; Palomba, S; Pellicano, M; Russo, T; Saraco, P; Zullo, F; Zupi, E, 2004)
"Phenazopyridine has been associated with methemoglobinemia in patients who have received an overdose, have decreased renal function, or are discovered to be unusually susceptible to the drug (ie, they may have an undetected NADH methemoglobin reductase deficiency)."3.68Acquired methemoglobinemia from multiple oxidants. ( Bailey, MK; Baker, JD; Conroy, JM; Dorman, BH; Martin, WJ, 1993)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's3 (37.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Selvi, O1
Tulgar, S1
Powell, MF1
Sakawi, Y1
El Hachem, L1
Small, E1
Chung, P1
Moshier, EL1
Friedman, K1
Fenske, SS1
Gretz, HF1
Seki, H1
Takizawa, Y1
Sodemoto, T1
Zullo, F1
Palomba, S1
Corea, D1
Pellicano, M1
Russo, T1
Falbo, A1
Barletta, E1
Saraco, P1
Doldo, P1
Zupi, E1
Kongnyuy, EJ1
van den Broek, N1
Wiysonge, CS1
Conroy, JM1
Baker, JD1
Martin, WJ1
Bailey, MK1
Dorman, BH1
Solak, M1
Aktürk, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Analgesic Efficacy of Transversus Abdominis Plane Block Versus Local Injection in Postoperative Pain Management Following Minimally Invasive Gynecological Surgery[NCT02314104]220 participants (Actual)Interventional2011-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Postoperative Pain on a Visual Analogue Pain Scale at One Hour Postoperatively

A Visual Analogue Scale was used. The scale range was 0 to 10 in increments of one. 0 was no pain and 10 was worst pain possible. (NCT02314104)
Timeframe: one hour postoperatively

Interventionunits on a scale (Mean)
Treatment TAP, Placebo Local Injection4.04
Placebo TAP, Treatment Local Injection5.09
Treatment TAP, Treatment Local Injection4.4

Postoperative Pain on a Visual Analogue Pain Scale at Six Hours Postoperatively

A Visual Analogue Scale was used. The scale range was 0 to 10 in increments of one. 0 was no pain and 10 was worst pain possible. (NCT02314104)
Timeframe: six hours postoperatively

Interventionunits on a scale (Mean)
Treatment TAP, Placebo Local Injection3.53
Placebo TAP, Treatment Local Injection3.5
Treatment TAP, Treatment Local Injection3.33

Postoperative Pain on a Visual Analogue Pain Scale at Twenty-four Hours Postoperatively

A Visual Analogue Scale was used. The scale range was 0 to 10 in increments of one. 0 was no pain and 10 was worst pain possible. (NCT02314104)
Timeframe: twenty-four hours postoperatively

Interventionunits on a scale (Mean)
Treatment TAP, Placebo Local Injection3.36
Placebo TAP, Treatment Local Injection3.56
Treatment TAP, Treatment Local Injection3.51

Time Until First Request for Pain Medication

(NCT02314104)
Timeframe: up to twenty-four hours postoperatively

Interventionminutes (Median)
Treatment TAP, Placebo Local Injection46
Placebo TAP, Treatment Local Injection31
Treatment TAP, Treatment Local Injection28

Total Narcotic Usage in Morphine Equivalents

(NCT02314104)
Timeframe: up to twenty-four hours postoperatively

Interventionmg (Mean)
Treatment TAP, Placebo Local Injection20.09
Placebo TAP, Treatment Local Injection23.14
Treatment TAP, Treatment Local Injection20.68

Reviews

1 review available for bupivacaine and Uterine Neoplasms

ArticleYear
A systematic review of randomized controlled trials to reduce hemorrhage during myomectomy for uterine fibroids.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2008, Volume: 100, Issue:1

    Topics: Blood Loss, Surgical; Bupivacaine; Combined Modality Therapy; Female; Gynecologic Surgical Procedure

2008

Trials

2 trials available for bupivacaine and Uterine Neoplasms

ArticleYear
Randomized controlled double-blind trial of transversus abdominis plane block versus trocar site infiltration in gynecologic laparoscopy.
    American journal of obstetrics and gynecology, 2015, Volume: 212, Issue:2

    Topics: Abdominal Muscles; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Cohort Studies;

2015
Bupivacaine plus epinephrine for laparoscopic myomectomy: a randomized placebo-controlled trial.
    Obstetrics and gynecology, 2004, Volume: 104, Issue:2

    Topics: Adult; Anesthetics, Local; Bupivacaine; Double-Blind Method; Epinephrine; Female; Humans; Injections

2004

Other Studies

5 other studies available for bupivacaine and Uterine Neoplasms

ArticleYear
Ultrasound guided erector spinae plane block as a cause of unintended motor block.
    Revista espanola de anestesiologia y reanimacion, 2018, Volume: 65, Issue:10

    Topics: Adult; Analgesia, Obstetrical; Bupivacaine; Cesarean Section; Diffusion; Female; Gait Disorders, Neu

2018
Aortocaval compression during early pregnancy: are there other causes?
    International journal of obstetric anesthesia, 2013, Volume: 22, Issue:2

    Topics: Adult; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Aorta, Thoracic; Bupivacaine; Fe

2013
Epidural analgesia for painful myomas refractory to medical therapy during pregnancy.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2003, Volume: 83, Issue:3

    Topics: Adult; Analgesia, Epidural; Biological Availability; Bupivacaine; Female; Humans; Leiomyoma; Materna

2003
Acquired methemoglobinemia from multiple oxidants.
    Southern medical journal, 1993, Volume: 86, Issue:10

    Topics: Administration, Topical; Adult; Analgesia, Epidural; Blood Gas Analysis; Bupivacaine; Cytochrome-B(5

1993
Spinal anesthesia in a patient with hyperthyroidism due to hydatidiform mole.
    Anesthesia and analgesia, 1993, Volume: 77, Issue:4

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Bupivacaine; Female; Humans; Hydatidiform Mole;

1993