bupivacaine and Urogenital Prolapse

bupivacaine has been researched along with Urogenital Prolapse in 3 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Research

Studies (3)

Authors

Clinical Trials (2)

Trial Overview

Trial Outcomes

Number of Patients With Early Anatomic Recurrence

To evaluate anatomical failure of posterior compartment using a standard definition of anatomical cure will be defined as Ba or Bp at NCT04658784)
Timeframe: Week 6

Suture Burden

To evaluate amount of suture burden present at time of surgery in posterior by compartment by measuring total amount of delayed absorbable suture used for posterior colporrhaphy in centimeters. (NCT04658784)
Timeframe: At time of surgery (Intraoperative)

American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) 30-day Postoperative Complications.

To evaluate differences in adverse outcomes, using number of adverse events (AEs) as defined by the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) 30-day postoperative complications criteria. These criteria were reviewed at the week 6 data collection time interval. (NCT04658784)
Timeframe: 30 days

Change in Bowel Function Scores

To evaluate change in bowel function using the Pelvic Floor Distress Inventory- 20 (PFDI-20) sub-scale Colorectal-Anal Distress Inventory-8 (CRADI-8). Total score (range 0 to 100) with the higher the score the more distress. (NCT04658784)
Timeframe: Baseline, Week 6, and month 6

Change in Pelvic Organ Prolapse Symptoms

To evaluate change in pelvic organ prolapse symptoms using the Pelvic Floor Distress Inventory- 20 (PFDI-20) sub-scale the Pelvic Organ Prolapse Distress Inventory- 6 (POPDI-6). Total score (range 0 to 100) with the higher the score the more distress. (NCT04658784)
Timeframe: Baseline, Week 6, and Month 6

Change in Postoperative Sexual Function Scores

To evaluate postoperative sexual function using the Pelvic Organ Prolapse-Urinary Incontinence Sexual Function Questionnaire (PISQ-12). Total score (range 0 to 48) with a lower score associated with poorer/worse sexual function. (NCT04658784)
Timeframe: Month 6

Number of Patients With Subjective Failure

"To evaluate subjective failure of posterior compartment using a negative response on POPDI-6 portion of the PFDI-20 questionnaire to questions: Do you usually have a sensation of bulging or protrusion from the vaginal area? and Do you usually have a bulge or something falling out that you can see or feel in the vaginal area?" (NCT04658784)
Timeframe: Week 6 and Month 6

Operative Time

To evaluate operative time for posterior repair in minutes. (NCT04658784)
Timeframe: Time of Surgery

Surgery Specific Adverse Events (AEs) Measured at 6-months.

To evaluate differences in adverse outcomes, using number of surgery specific adverse events. (NCT04658784)
Timeframe: month 6

Visual Analog Scales (VAS) for Pain at 18 Hours Postoperatively

VAS is a validated 100 millimeter scale with no pain as 0 mm and worst pain as 100 mm. Subjects drew a vertical line on the scale corresponding to their pain level. (NCT02449915)
Timeframe: 18 hours after surgery

Trials

3 trials available for bupivacaine and Urogenital Prolapse