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bupivacaine and Trigeminal Neuralgia

bupivacaine has been researched along with Trigeminal Neuralgia in 21 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Trigeminal Neuralgia: A syndrome characterized by recurrent episodes of excruciating pain lasting several seconds or longer in the sensory distribution of the TRIGEMINAL NERVE. Pain may be initiated by stimulation of trigger points on the face, lips, or gums or by movement of facial muscles or chewing. Associated conditions include MULTIPLE SCLEROSIS, vascular anomalies, ANEURYSMS, and neoplasms. (Adams et al., Principles of Neurology, 6th ed, p187)

Research Excerpts

ExcerptRelevanceReference
"To assess the effect of bupivacaine application following pulsed radiofrequency (PRF) ablation on trigeminal facial pain."9.51Efficacy of bupivacaine injection after pulsed radiofrequency ablation in the management of trigeminal facial pain: A prospective, randomized, and double-blind study. ( Alyamani, OA; Hilal, FM; Kaki, AM, 2022)
"To assess the effect of bupivacaine application following pulsed radiofrequency (PRF) ablation on trigeminal facial pain."5.51Efficacy of bupivacaine injection after pulsed radiofrequency ablation in the management of trigeminal facial pain: A prospective, randomized, and double-blind study. ( Alyamani, OA; Hilal, FM; Kaki, AM, 2022)
"Background Trigeminal neuralgia is a neuropathic disorder characterized by episodes of intense pain in the face."5.42Real-time ultrasound-guided infraorbital nerve block to treat trigeminal neuralgia using a high concentration of tetracaine dissolved in bupivacaine. ( Fujii, T; Fujioka, S; Kikuchi, K; Konishi, A; Kuzume, K; Nagaro, T; Takechi, K; Yorozuya, T, 2015)
"Bupivacaine injections were well tolerated; no ill-effects of the drug were observed."5.25The use of bupivacaine for blocking the Gasserian ganglion in major trigeminal neuralgia. ( Adler, P, 1975)
" One minute after performing a second stellate ganglion block the patient showed signs of apnea and paralysis of the upper extremities and face, with no involvement of oculomotor muscles or the lower extremities, and no loss of consciousness."3.70[A possibility of central diffusion during stellate ganglion blockade: "the sheath of the spinal rachidian nerve"]. ( Escudero, A; Fas, MJ; Ortiz, M; Roca, G; Soriano, C; Vidal, F, 1999)
"A 56 year old, white female with a diagnosis of trigeminal neuralgia, unresponsive to medical therapy, received a sphenopalatine ganglion block using bupivacaine 0."3.69Sphenopalatine ganglion block relieves symptoms of trigeminal neuralgia: a case report. ( Malesker, MA; Malone, PM; Manahan, AP, 1996)
"Acute neurogenic pulmonary edema developed immediately after injection of bupivacaine hydrochloride into the trigeminal cistern of a 32-year-old man with atypical facial pain and no prior history of cardiopulmonary problems."3.67Neurogenic pulmonary edema after trigeminal nerve blockade. ( Brown, J; Feuerman, T; Wright, RS, 1989)
"Background Trigeminal neuralgia is a neuropathic disorder characterized by episodes of intense pain in the face."1.42Real-time ultrasound-guided infraorbital nerve block to treat trigeminal neuralgia using a high concentration of tetracaine dissolved in bupivacaine. ( Fujii, T; Fujioka, S; Kikuchi, K; Konishi, A; Kuzume, K; Nagaro, T; Takechi, K; Yorozuya, T, 2015)
"This condition, characterized by gustatory sweating and facial hyperemia, is occasionally associated with pain, which is usually described as aching or burning, and long-lasting."1.28Auriculotemporal syndrome (Frey's syndrome) presenting as tic douloureux. Report of two cases. ( De Benedittis, G, 1990)
"Bupivacaine injections were well tolerated; no ill-effects of the drug were observed."1.25The use of bupivacaine for blocking the Gasserian ganglion in major trigeminal neuralgia. ( Adler, P, 1975)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19906 (28.57)18.7374
1990's4 (19.05)18.2507
2000's3 (14.29)29.6817
2010's7 (33.33)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Hilal, FM1
Alyamani, OA1
Kaki, AM1
Takechi, K1
Konishi, A1
Kikuchi, K1
Fujioka, S1
Fujii, T1
Yorozuya, T1
Kuzume, K1
Nagaro, T1
Qureshi, AI1
Naseem, N1
Saleem, MA1
Wallery, SS1
Raja, F1
Perloff, MD1
Chung, JS1
Ilik, MK1
Ilik, F1
Sayegh, RR1
Sweet, JA1
Miller, JP1
Hayek, SM1
Dergin, G1
Gocmen, G1
Sener, BC1
Nader, A1
Schittek, H1
Kendall, MC1
Chang, FL1
Huang, GS1
Cherng, CH1
Ho, ST1
Wong, CS1
Naja, MZ1
Al-Tannir, M1
Naja, H1
Ziade, MF1
Zeidan, A1
Nique, TA1
Bennett, CR1
Manahan, AP1
Malesker, MA1
Malone, PM1
Goto, F1
Ishizaki, K1
Yoshikawa, D1
Obata, H1
Arii, H1
Terada, M1
Soriano, C1
Ortiz, M1
Fas, MJ1
Escudero, A1
Roca, G1
Vidal, F1
Yokoyama, M1
Ohashi, I1
Nakatsuka, H1
Mizobuchi, S1
Toda, Y1
Matsumi, M1
Morita, K1
Hirakawa, M1
Adler, P1
De Benedittis, G1
Wright, RS1
Feuerman, T1
Brown, J1
Gáspár, L1
Swerdlow, M1
Bencze, J1

Trials

2 trials available for bupivacaine and Trigeminal Neuralgia

ArticleYear
Efficacy of bupivacaine injection after pulsed radiofrequency ablation in the management of trigeminal facial pain: A prospective, randomized, and double-blind study.
    Saudi medical journal, 2022, Volume: 43, Issue:6

    Topics: Bupivacaine; Catheter Ablation; Double-Blind Method; Facial Pain; Humans; Prospective Studies; Pulse

2022
Treatment of trigeminal neuralgia with bupivacaine HCL using a temporary epidural catheter and pain pump: preliminary study.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2012, Volume: 40, Issue:2

    Topics: Adult; Aged; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Catheters, Indwelling; Female; H

2012

Other Studies

19 other studies available for bupivacaine and Trigeminal Neuralgia

ArticleYear
Real-time ultrasound-guided infraorbital nerve block to treat trigeminal neuralgia using a high concentration of tetracaine dissolved in bupivacaine.
    Scandinavian journal of pain, 2015, Jan-01, Volume: 6, Issue:1

    Topics: Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Female; Humans; Male; Middle Aged; Nerve B

2015
Electrophysiological Monitoring During Percutaneous Trigeminal Nerve Ganglion Block.
    Journal of neurosurgical anesthesiology, 2019, Volume: 31, Issue:4

    Topics: Anesthetics, Local; Blinking; Bupivacaine; Electrophysiological Phenomena; Humans; Lidocaine; Monito

2019
Urgent care peripheral nerve blocks for refractory trigeminal neuralgia.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:11

    Topics: Ambulatory Care; Anesthetics, Local; Bupivacaine; Humans; Lidocaine; Nerve Block; Outpatient Clinics

2018
Evaluation of the Retrogasserian Opioid Application in the Treatment of Idiopathic Trigeminal Neuralgia.
    Turkish neurosurgery, 2019, Volume: 29, Issue:5

    Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Female; Fentanyl; Humans; Male; Mi

2019
Electrical Stimulation of the Trigeminal Ganglion and Intrathecal Drug Delivery Systems for the Management of Corneal Neuropathic Pain.
    Cornea, 2016, Volume: 35, Issue:4

    Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Combined Modality Therapy; Corneal Disea

2016
Lateral pterygoid muscle and maxillary artery are key anatomical landmarks for ultrasound-guided trigeminal nerve block.
    Anesthesiology, 2013, Volume: 118, Issue:4

    Topics: Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Dexamethasone; Female; Humans; Maxillary

2013
Repeated peripheral nerve blocks by the co-administration of ketamine, morphine, and bupivacaine attenuate trigeminal neuralgia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2003, Volume: 50, Issue:2

    Topics: Analgesics, Opioid; Anesthesia, Local; Anesthetics, Dissociative; Bupivacaine; Chronic Disease; Huma

2003
Repeated nerve blocks with clonidine, fentanyl and bupivacaine for trigeminal neuralgia.
    Anaesthesia, 2006, Volume: 61, Issue:1

    Topics: Anesthetics; Bupivacaine; Chronic Disease; Clonidine; Electric Stimulation; Fentanyl; Humans; Nerve

2006
Inadvertent brainstem anesthesia following extraoral trigeminal V2-V3 blocks.
    Oral surgery, oral medicine, and oral pathology, 1981, Volume: 51, Issue:5

    Topics: Aged; Analgesics; Anesthesia, Local; Brain Stem; Bupivacaine; Female; Humans; Nerve Block; Plant Ext

1981
Sphenopalatine ganglion block relieves symptoms of trigeminal neuralgia: a case report.
    The Nebraska medical journal, 1996, Volume: 81, Issue:9

    Topics: Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Female; Ganglia, Parasympathetic; Humans; Mi

1996
The long lasting effects of peripheral nerve blocks for trigeminal neuralgia using high concentration of tetracaine dissolved in bupivacaine.
    Pain, 1999, Volume: 79, Issue:1

    Topics: Aged; Aged, 80 and over; Anesthetics, Combined; Bupivacaine; Dose-Response Relationship, Drug; Femal

1999
[A possibility of central diffusion during stellate ganglion blockade: "the sheath of the spinal rachidian nerve"].
    Revista espanola de anestesiologia y reanimacion, 1999, Volume: 46, Issue:3

    Topics: Adult; Anesthetics, Local; Apnea; Autonomic Nerve Block; Bupivacaine; Diffusion; Facial Paralysis; F

1999
Drug-induced liver disease during continuous epidural block with bupivacaine.
    Anesthesiology, 2001, Volume: 95, Issue:1

    Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Anesthetics, Local; Bupivacaine; Chemical and Drug Ind

2001
The use of bupivacaine for blocking the Gasserian ganglion in major trigeminal neuralgia.
    International journal of oral surgery, 1975, Volume: 4, Issue:6

    Topics: Aged; Bupivacaine; Female; Humans; Injections, Spinal; Male; Middle Aged; Nerve Block; Trigeminal Ne

1975
Auriculotemporal syndrome (Frey's syndrome) presenting as tic douloureux. Report of two cases.
    Journal of neurosurgery, 1990, Volume: 72, Issue:6

    Topics: Aged; Bupivacaine; Diagnosis, Differential; Female; Humans; Male; Nerve Block; Pain; Palliative Care

1990
Neurogenic pulmonary edema after trigeminal nerve blockade.
    Chest, 1989, Volume: 96, Issue:2

    Topics: Adult; Bupivacaine; Humans; Male; Nerve Block; Pulmonary Edema; Trigeminal Nerve; Trigeminal Neuralg

1989
[Experience with the conservative management of facial neuralgia].
    Fogorvosi szemle, 1985, Volume: 78, Issue:6

    Topics: Adult; Aged; Bupivacaine; Carbamazepine; Electric Stimulation Therapy; Facial Neuralgia; Female; Hum

1985
Relieving pain in the terminally ill.
    Geriatrics, 1973, Volume: 28, Issue:7

    Topics: Administration, Oral; Alcohols; Anesthesia, Spinal; Antidepressive Agents; Autonomic Nerve Block; Bu

1973
[The use of marcain in trigeminal neuralgia and related pain].
    Fogorvosi szemle, 1972, Volume: 65, Issue:12

    Topics: Adult; Aged; Bupivacaine; Female; Humans; Male; Middle Aged; Trigeminal Neuralgia

1972