bupivacaine has been researched along with Tonsillitis in 9 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Tonsillitis: Inflammation of the tonsils, especially the PALATINE TONSILS but the ADENOIDS (pharyngeal tonsils) and lingual tonsils may also be involved. Tonsillitis usually is caused by bacterial infection. Tonsillitis may be acute, chronic, or recurrent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The operation time, postoperative pain, amount of intraoperative blood loss, postoperative hemorrhage and complications were assessed." | 2.77 | Comparison of ropivacaine, bupivacaine and lidocaine in the management of post-tonsillectomy pain. ( Kapusuz, Z; Ozkiriş, M; Saydam, L, 2012) |
| "Bupivacaine was applied on both sides randomized in different ways." | 2.74 | Application methods of local anaesthetic infiltrations for postoperative pain relief in tonsillectomy: a prospective, randomised, double-blind, clinical trial. ( Andratschke, M; Berghaus, A; Hagedorn, H; Hempel, JM; Luebbers, CW; Stelter, K, 2009) |
| "The subjective measure of postoperative pain was a questionnaire based on a standard visual analog scale ranging from 0 to 10." | 2.71 | Microdissection needle tonsillectomy and postoperative pain: a pilot study. ( Dahiya, R; Perkins, J, 2003) |
| "Postoperative pain was assessed at regular intervals by using three methods: (1) use of a visual analogue scale by parents and nurses to estimate pain; (2) postoperative need for nalbuphine as analgesic; (3) the Hannallah-Broadman semi-objective pain score (including crying, anxiety, restlessness, and changes in blood pressure)." | 2.68 | [Local infiltration of epinephrine and bupivacaine before tonsillectomy]. ( Erb, T; Frei, F; Kern, C; Strub, KA; Tschopp, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Yücel Ekici, N | 1 |
| Özdoğan, H | 1 |
| Arikan, OK | 1 |
| Sahin, S | 1 |
| Kazkayasi, M | 1 |
| Muluk, NB | 1 |
| Akpinar, S | 1 |
| Kilic, R | 1 |
| Stelter, K | 1 |
| Hempel, JM | 1 |
| Berghaus, A | 1 |
| Andratschke, M | 1 |
| Luebbers, CW | 1 |
| Hagedorn, H | 1 |
| Hydri, AS | 1 |
| Malik, SM | 1 |
| Dahi-Taleghani, M | 1 |
| Mousavifard, S | 1 |
| Tahmoureszade, S | 1 |
| Dabbagh, A | 1 |
| Moss, JR | 1 |
| Cofer, S | 1 |
| Hersey, S | 1 |
| Goudy, S | 1 |
| Werkhaven, J | 1 |
| Swanson, E | 1 |
| Mantle, C | 1 |
| Stowell, N | 1 |
| Byrne, D | 1 |
| Wang, L | 1 |
| Labadie, R | 1 |
| Ozkiriş, M | 1 |
| Kapusuz, Z | 1 |
| Saydam, L | 1 |
| Perkins, J | 1 |
| Dahiya, R | 1 |
| Strub, KA | 1 |
| Tschopp, K | 1 |
| Frei, F | 1 |
| Kern, C | 1 |
| Erb, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pediatric Tonsillectomy Pain Reduction Study, a Randomized, Placebo Controlled, Double-Blind Clinical Trial Using Clonidine and Local Anesthetics[NCT00678379] | Phase 3 | 120 participants (Actual) | Interventional | 2008-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The median number of intravenous fentanyl doses administered in the PACU due to pain (NCT00678379)
Timeframe: in recovery room
| Intervention | number of doses (Median) |
|---|---|
| Normal Saline | 3.0 |
| Lidocaine (1%) + Bupivacaine 0.5% | 3 |
| Lidocaine 1% + Bupivacaine o.5% + Clondine 25mcg | 3 |
The total number of intravenous fentanyl doses given PACU which will be compared between the three randomized groups (arms) (NCT00678379)
Timeframe: Post-operative thru day 7
| Intervention | number of doses (Median) |
|---|---|
| Normal Saline | 12 |
| Lidocaine (1%) + Bupivacaine 0.5% | 12 |
| Lidocaine 1% + Bupivacaine o.5% + Clondine 25mcg | 14 |
(NCT00678379)
Timeframe: Day of Surgery
| Intervention | minutes (Median) |
|---|---|
| Normal Saline | 122 |
| Lidocaine (1%) + Bupivacaine 0.5% | 111 |
| Lidocaine 1% + Bupivacaine o.5% + Clondine 25mcg | 120 |
Visual analog pain scale range is 0-10 with 0=no pain and 10 = worst pain ever (NCT00678379)
Timeframe: in recovery room; post-operative days 1,3,5 & 7
| Intervention | pain score (Mean) | ||||
|---|---|---|---|---|---|
| In recovery room | day 1 | day 3 | day 5 | day 7 | |
| Lidocaine (1%) + Bupivacaine 0.5% | 3 | 4 | 2.5 | 2 | 2 |
| Lidocaine 1% + Bupivacaine o.5% + Clondine 25mcg | 3 | 5 | 3 | 3 | 2 |
| Normal Saline | 3 | 3 | 3 | 3 | 2.5 |
The number and percent of patients whose post-operative diet has to a regular diet on post-operative days 1, 3, 5 & 7 (NCT00678379)
Timeframe: post-operative days 1,3,5 & 7.
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| post-op day 1 | post-op day 3 | post op day 5 | post op day 7 | |
| Lidocaine (1%) + Bupivacaine 0.5% | 4 | 8 | 18 | 26 |
| Lidocaine 1% + Bupivacaine o.5% + Clondine 25mcg | 1 | 12 | 14 | 22 |
| Normal Saline | 7 | 18 | 21 | 24 |
The number and percent of patients whose post-operative diet has only advanced to a soft diet on post-operative days 1, 3, 5 & 7 (NCT00678379)
Timeframe: post-operative days 1,3,5 & 7.
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| post-op day 1 | post-op day 3 | post op day 5 | post op day 7 | |
| Lidocaine (1%) + Bupivacaine 0.5% | 22 | 26 | 17 | 10 |
| Lidocaine 1% + Bupivacaine o.5% + Clondine 25mcg | 26 | 18 | 18 | 14 |
| Normal Saline | 26 | 18 | 13 | 13 |
The number and percent of patients whose post-operative diet has advanced to liquids only on post-op days 1, 3, 5 & 7 (NCT00678379)
Timeframe: post-operative days 1,3,5 & 7.
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| post-op day 1 | post-op day 3 | post op day 5 | post op day 7 | |
| Lidocaine (1%) + Bupivacaine 0.5% | 33 | 13 | 10 | 11 |
| Lidocaine 1% + Bupivacaine o.5% + Clondine 25mcg | 30 | 23 | 19 | 10 |
| Normal Saline | 16 | 8 | 13 | 6 |
9 trials available for bupivacaine and Tonsillitis
| Article | Year |
|---|---|
Comparing local anesthetic infiltration of the peritonsillar region and glossotonsillar sulcus for post-tonsillectomy pain management.
Topics: Analgesics; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Deglutition | 2020 |
High-dose ropivacaine versus bupivacaine for posttonsillectomy pain relief in adults.
Topics: Adult; Amides; Analgesics; Anesthetics, Local; Bupivacaine; Dose-Response Relationship, Drug; Double | 2008 |
Application methods of local anaesthetic infiltrations for postoperative pain relief in tonsillectomy: a prospective, randomised, double-blind, clinical trial.
Topics: Adolescent; Adult; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Doub | 2009 |
Post-tonsillectomy pain and bupivacaine, an intra individual design study.
Topics: Adolescent; Adult; Anesthetics, Local; Bupivacaine; Child; Female; Humans; Male; Pain Measurement; P | 2010 |
Rectal acetaminophen versus peritonsillar infiltration of bupivacaine for postoperative analgesia after adenotonsillectomy in children.
Topics: Acetaminophen; Acute Disease; Administration, Rectal; Adolescent; Analgesics, Non-Narcotic; Anesthes | 2011 |
Comparison of clonidine, local anesthetics, and placebo for pain reduction in pediatric tonsillectomy.
Topics: Adenoids; Adolescent; Age Factors; Analgesics; Anesthetics, Local; Bupivacaine; Child; Child, Presch | 2011 |
Comparison of ropivacaine, bupivacaine and lidocaine in the management of post-tonsillectomy pain.
Topics: Adenoidectomy; Administration, Topical; Adolescent; Age Factors; Amides; Anesthetics, Local; Blood L | 2012 |
Microdissection needle tonsillectomy and postoperative pain: a pilot study.
Topics: Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Electrocoagulation; Female; Humans; Male; | 2003 |
[Local infiltration of epinephrine and bupivacaine before tonsillectomy].
Topics: Adenoidectomy; Anesthesia, Local; Blood Loss, Surgical; Bupivacaine; Child; Child, Preschool; Epinep | 1996 |