bupivacaine has been researched along with Thyroid Diseases in 4 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Thyroid Diseases: Pathological processes involving the THYROID GLAND.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Egan, RJ | 1 |
| Hopkins, JC | 1 |
| Beamish, AJ | 1 |
| Shah, R | 1 |
| Edwards, AG | 1 |
| Morgan, JD | 1 |
| Shih, ML | 1 |
| Duh, QY | 1 |
| Hsieh, CB | 1 |
| Liu, YC | 1 |
| Lu, CH | 1 |
| Wong, CS | 1 |
| Yu, JC | 1 |
| Yeh, CC | 1 |
| Steffen, T | 1 |
| Warschkow, R | 1 |
| Brändle, M | 1 |
| Tarantino, I | 1 |
| Clerici, T | 1 |
| Arora, N | 1 |
| Dhar, P | 1 |
| Fahey, TJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Feasibility of Bilateral Intermediate Cervical Plexus Block for Thyroidectomy/Parathyroidectomy Under Moderate Sedation; Retrospective Study[NCT04905641] | 19 participants (Actual) | Observational | 2016-03-10 | Completed | |||
| Efficacy of Adding Dexmedetomidine as Adjuvant With Bupivacaine in Ultrasound-guided Intermediate Cervical Plexus Block for Thyroidectomy Surgery: Randomized Controlled Study[NCT05814744] | 60 participants (Anticipated) | Interventional | 2023-04-30 | Not yet recruiting | |||
| Impact and Cost Efficiency of Bilateral, Superficial Cervical Block in Thyroid Surgery Under General Anesthesia[NCT00472446] | Phase 2/Phase 3 | 183 participants (Actual) | Interventional | 2006-01-31 | Completed | ||
| Evaluation of the Postoperative Analgesic Efficacy of Bilateral Superficial Cervical Block for Thyroidectomy and Mini Incision Under General Balanced Anesthesia: a Randomized, Triple Masked, Placebo Controlled Trial.[NCT01171885] | Phase 4 | 120 participants (Anticipated) | Interventional | 2009-07-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
time from surgery to Hospital release in days (NCT00472446)
Timeframe: 90 days
| Intervention | days (Mean) |
|---|---|
| Cervivcal Block Before Surgery | 1.8 |
| Cervivcal Block After Surgery | 1.6 |
| Placebo Cervivcal Block Before Surgery | 2.0 |
| Placebo Cervivcal Block After Surgery | 1.6 |
"Pain was obtained using the visual analog scale (VAS) three times daily for the 4 postoperative days (0 = no pain, 10 = worst imaginable pain)~The pooled relative treatment effect is the probability of values being higher in one group than in another group (ranging from 0 to 1)" (NCT00472446)
Timeframe: 4 days after surgery
| Intervention | pooled relative treatment effect (Number) |
|---|---|
| Cervivcal Block Before Surgery | 0.47 |
| Cervivcal Block After Surgery | 0.45 |
| Placebo Cervivcal Block Before Surgery | 0.55 |
| Placebo Cervivcal Block After Surgery | 0.54 |
Patient administered Instrument to indicate pain on a level from 0 to 10. (0: no pain, 10: worst imaginable pain) (NCT00472446)
Timeframe: 24 hours after surgery
| Intervention | units on a scale (Mean) |
|---|---|
| Cervivcal Block Before Surgery | 1.95 |
| Cervivcal Block After Surgery | 1.51 |
| Placebo Cervivcal Block Before Surgery | 2.20 |
| Placebo Cervivcal Block After Surgery | 2.06 |
Patient administered Instrument to indicate pain on a level from 0 to 10. (0: no pain, 10: worst imaginable pain) (NCT00472446)
Timeframe: 6 hours after surgery
| Intervention | units on a scale (Mean) |
|---|---|
| Cervivcal Block Before Surgery | 2.15 |
| Cervivcal Block After Surgery | 2.02 |
| Placebo Cervivcal Block Before Surgery | 2.84 |
| Placebo Cervivcal Block After Surgery | 2.72 |
number of participants taking post-operative analgetics (NCT00472446)
Timeframe: 5 days after surgery
| Intervention | participants (Number) | |
|---|---|---|
| paracetamol | metamizole | |
| Cervivcal Block After Surgery | 23 | 7 |
| Cervivcal Block Before Surgery | 21 | 6 |
| Placebo Cervivcal Block After Surgery | 24 | 7 |
| Placebo Cervivcal Block Before Surgery | 18 | 3 |
mean pooled dose of post-operative analgetics (NCT00472446)
Timeframe: 5 days after surgery
| Intervention | gram (Mean) | |
|---|---|---|
| paracetamol | metamizole | |
| Cervivcal Block After Surgery | 3.37 | .93 |
| Cervivcal Block Before Surgery | 3.33 | 1.25 |
| Placebo Cervivcal Block After Surgery | 4.33 | 1.21 |
| Placebo Cervivcal Block Before Surgery | 4.06 | 2.46 |
1 review available for bupivacaine and Thyroid Diseases
| Article | Year |
|---|---|
Seminars: local and regional anesthesia for thyroid surgery.
Topics: Amides; Anesthesia, Conduction; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Endocrine Surgic | 2006 |
3 trials available for bupivacaine and Thyroid Diseases
| Article | Year |
|---|---|
Randomized clinical trial of intraoperative superficial cervical plexus block versus incisional local anaesthesia in thyroid and parathyroid surgery.
Topics: Aged; Analgesics; Anesthesia, Local; Anesthetics, Local; Area Under Curve; Bupivacaine; Cervical Ple | 2013 |
Randomized clinical trial of intraoperative superficial cervical plexus block versus incisional local anaesthesia in thyroid and parathyroid surgery.
Topics: Aged; Analgesics; Anesthesia, Local; Anesthetics, Local; Area Under Curve; Bupivacaine; Cervical Ple | 2013 |
Randomized clinical trial of intraoperative superficial cervical plexus block versus incisional local anaesthesia in thyroid and parathyroid surgery.
Topics: Aged; Analgesics; Anesthesia, Local; Anesthetics, Local; Area Under Curve; Bupivacaine; Cervical Ple | 2013 |
Randomized clinical trial of intraoperative superficial cervical plexus block versus incisional local anaesthesia in thyroid and parathyroid surgery.
Topics: Aged; Analgesics; Anesthesia, Local; Anesthetics, Local; Area Under Curve; Bupivacaine; Cervical Ple | 2013 |
Bilateral superficial cervical plexus block combined with general anesthesia administered in thyroid operations.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthetics, Local; Bupivacaine; Cervical Plexus; Fema | 2010 |
Randomized controlled trial of bilateral superficial cervical plexus block versus placebo in thyroid surgery.
Topics: Adolescent; Adult; Aged; Analgesics; Analysis of Variance; Anesthetics, Local; Bupivacaine; Cervical | 2010 |
Randomized controlled trial of bilateral superficial cervical plexus block versus placebo in thyroid surgery.
Topics: Adolescent; Adult; Aged; Analgesics; Analysis of Variance; Anesthetics, Local; Bupivacaine; Cervical | 2010 |
Randomized controlled trial of bilateral superficial cervical plexus block versus placebo in thyroid surgery.
Topics: Adolescent; Adult; Aged; Analgesics; Analysis of Variance; Anesthetics, Local; Bupivacaine; Cervical | 2010 |
Randomized controlled trial of bilateral superficial cervical plexus block versus placebo in thyroid surgery.
Topics: Adolescent; Adult; Aged; Analgesics; Analysis of Variance; Anesthetics, Local; Bupivacaine; Cervical | 2010 |