Page last updated: 2024-10-24

bupivacaine and Tachycardia, Ventricular

bupivacaine has been researched along with Tachycardia, Ventricular in 19 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).

Research Excerpts

ExcerptRelevanceReference
"Although Volatile Induction and Maintenance of Anesthesia (VIMA) with sevoflurane might prolong the QTc interval and did not result in arrhythmia, selective spinal anesthesia with bupivacaine was not associated with alterations in the QT interval or arrhythmia."5.14The effects of volatile induction and maintenance of anesthesia and selective spinal anesthesia on QT interval, QT dispersion, and arrhythmia incidence. ( Alkent, ZP; Basaran, M; Dikmen, B; Ekin, A; Ornek, D; Ornek, E, 2010)
"Successful cardioversion of ventricular tachycardia in a full-term male infant, born severely depressed by emergency Cesarean section 9 min after the mother was given bilateral paracervical bupivacaine blocks for pain relief during normal labor, is described."2.38Rare procedures during delivery room resuscitation--cardioversion of ventricular tachycardia in an asphyctic neonate. ( Heinonen, KM, 1992)
"Bupivacaine 0."1.56Emergent Phenol Injection of Bilateral Stellate Ganglion for Management of Refractory Malignant Ventricular Arrhythmias. ( Daoud, EG; Latif, OS; Luke, WR, 2020)
"While monomorphic ventricular tachycardia and PVC-triggered polymorphic ventricular tachycardia may sometimes be amenable to successful ablation, some patients may be too critically ill to make such an approach feasible."1.46Autonomic Modulation for the Treatment of Ventricular Arrhythmias: Therapeutic Use of Percutaneous Stellate Ganglion Blocks. ( Boortz-Marx, R; Fudim, M; Patel, CB; Piccini, JP; Sun, AY, 2017)
"Bupivacaine was infused with a syringe driver via central venous catheter at a rate of 1 mg·kg(-1)·min(-1) until circulatory arrest."1.38Resuscitation strategies from bupivacaine-induced cardiac arrest. ( Bettschart-Wolfensberger, R; Jurado, OM; Mauch, J; Spielmann, N; Weiss, M, 2012)
"The doses of bupivacaine inducing seizure and ventricular tachycardia were significantly higher for liposomal bupivacaine than for the two plain solutions."1.29Toxicity of bupivacaine encapsulated into liposomes and injected intravenously: comparison with plain solutions. ( Akodad, EM; Benameur, H; Boogaerts, J; Declercq, A; Dupont, JC; Lafont, N; Legros, FJ, 1993)
"Seventeen animals responded with ventricular tachycardia (VT) within 3 min."1.29Epinephrine dysrhythmogenicity is not enhanced by subtoxic bupivacaine in dogs. ( Bosnjak, ZJ; Hoffmann, RG; Hogan, QH; Kulier, AH; Novalija, E; Turner, LA; Woehlck, HJ, 1996)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (31.58)18.2507
2000's4 (21.05)29.6817
2010's7 (36.84)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Luke, WR1
Daoud, EG1
Latif, OS1
Sharma, SP1
Turagam, MK1
Mohanty, S1
Di Biase, L1
Burkhardt, D1
Horton, R1
Natale, A1
Lakkireddy, D1
Meng, L1
Tseng, CH1
Shivkumar, K2
Ajijola, O1
De Diego, C1
Zaballos, M1
Quintela, O1
Sevilla, R1
Callejo, D1
González-Panizo, J1
Anadón, MJ1
Almendral, J1
Mata Francisco, NC1
Gómez Pesquera, E1
Ruiz López, N1
Álvarez López, JC1
Jorge-Monjas, P1
Buck, D1
Kreeger, R1
Spaeth, J1
Fudim, M1
Boortz-Marx, R1
Patel, CB1
Sun, AY1
Piccini, JP1
Ornek, E1
Ornek, D1
Alkent, ZP1
Ekin, A1
Basaran, M1
Dikmen, B1
Mauch, J1
Jurado, OM1
Spielmann, N1
Bettschart-Wolfensberger, R1
Weiss, M1
Srinivasa, V1
Gerner, P1
Haderer, A1
Abdi, S1
Jarolim, P1
Wang, GK1
Mahajan, A1
Moore, J1
Cesario, DA1
Issa, ZF1
Zipes, DP1
Ved, SA1
Pinosky, M1
Nicodemus, H1
Boogaerts, J1
Declercq, A1
Lafont, N1
Benameur, H1
Akodad, EM1
Dupont, JC1
Legros, FJ1
Kulier, AH1
Woehlck, HJ1
Hogan, QH1
Hoffmann, RG1
Novalija, E1
Turner, LA1
Bosnjak, ZJ1
Lee, BB1
Chen, PP1
Chiu, A1
Groban, L1
Deal, DD1
Vernon, JC1
James, RL1
Butterworth, J1
Heinonen, KM1
Knapik, P1
Gallert, G1
Knapik, M1
Antoszewski, Z1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Endocardial-Epicardial Radiofrequency Ablation of Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy[NCT04512911]Early Phase 10 participants (Actual)Interventional2023-01-31Withdrawn (stopped due to IRB approval expired 1/23/2023 and eclipsed the 6 month institutional window where study can be reinitiated via progress report. No enrollment has taken place.)
Pre-Operative Stellate Ganglion to Prevent Post-Operative Atrial Fibrillation[NCT05656170]0 participants (Actual)Interventional2023-10-01Withdrawn (stopped due to Unable to begin study)
Can Stellar Ganglion Blockage be an Alternative Treatment for Refractory Ventricular Arrhythmias?[NCT05712122]10 participants (Actual)Interventional2021-01-01Completed
Prophylactic Cardiac Sympathetic Denervation for Prevention of Ventricular Tachyarrhythmias (PREVENT VT)[NCT01013714]Phase 340 participants (Anticipated)Interventional2021-07-26Recruiting
Safety of Local Dental Anesthesia in Patients With Cardiac Channelopathies[NCT03182777]31 participants (Actual)Interventional2015-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for bupivacaine and Tachycardia, Ventricular

ArticleYear
Efficacy of Stellate Ganglion Blockade in Managing Electrical Storm: A Systematic Review.
    JACC. Clinical electrophysiology, 2017, Volume: 3, Issue:9

    Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Female; Humans; Male; Middle Ag

2017
Efficacy of Stellate Ganglion Blockade in Managing Electrical Storm: A Systematic Review.
    JACC. Clinical electrophysiology, 2017, Volume: 3, Issue:9

    Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Female; Humans; Male; Middle Ag

2017
Efficacy of Stellate Ganglion Blockade in Managing Electrical Storm: A Systematic Review.
    JACC. Clinical electrophysiology, 2017, Volume: 3, Issue:9

    Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Female; Humans; Male; Middle Ag

2017
Efficacy of Stellate Ganglion Blockade in Managing Electrical Storm: A Systematic Review.
    JACC. Clinical electrophysiology, 2017, Volume: 3, Issue:9

    Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Female; Humans; Male; Middle Ag

2017
Efficacy of Stellate Ganglion Blockade in Managing Electrical Storm: A Systematic Review.
    JACC. Clinical electrophysiology, 2017, Volume: 3, Issue:9

    Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Female; Humans; Male; Middle Ag

2017
Efficacy of Stellate Ganglion Blockade in Managing Electrical Storm: A Systematic Review.
    JACC. Clinical electrophysiology, 2017, Volume: 3, Issue:9

    Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Female; Humans; Male; Middle Ag

2017
Efficacy of Stellate Ganglion Blockade in Managing Electrical Storm: A Systematic Review.
    JACC. Clinical electrophysiology, 2017, Volume: 3, Issue:9

    Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Female; Humans; Male; Middle Ag

2017
Efficacy of Stellate Ganglion Blockade in Managing Electrical Storm: A Systematic Review.
    JACC. Clinical electrophysiology, 2017, Volume: 3, Issue:9

    Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Female; Humans; Male; Middle Ag

2017
Efficacy of Stellate Ganglion Blockade in Managing Electrical Storm: A Systematic Review.
    JACC. Clinical electrophysiology, 2017, Volume: 3, Issue:9

    Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Female; Humans; Male; Middle Ag

2017
Rare procedures during delivery room resuscitation--cardioversion of ventricular tachycardia in an asphyctic neonate.
    Intensive care medicine, 1992, Volume: 18, Issue:8

    Topics: Analgesia, Obstetrical; Asphyxia Neonatorum; Bupivacaine; Cesarean Section; Electric Countershock; E

1992
[Controversies regarding the use of 0.75% bupivacaine].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1992, Volume: 45, Issue:13-14

    Topics: Analgesia; Anesthesia, Epidural; Anesthesia, Local; Bupivacaine; Dose-Response Relationship, Drug; D

1992

Trials

1 trial available for bupivacaine and Tachycardia, Ventricular

ArticleYear
The effects of volatile induction and maintenance of anesthesia and selective spinal anesthesia on QT interval, QT dispersion, and arrhythmia incidence.
    Clinics (Sao Paulo, Brazil), 2010, Volume: 65, Issue:8

    Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Anesthetics, Local; Arrhythmias, Cardiac; Bupivaca

2010

Other Studies

15 other studies available for bupivacaine and Tachycardia, Ventricular

ArticleYear
Emergent Phenol Injection of Bilateral Stellate Ganglion for Management of Refractory Malignant Ventricular Arrhythmias.
    The American journal of case reports, 2020, Mar-19, Volume: 21

    Topics: Ablation Techniques; Bupivacaine; Fluoroscopy; Humans; Injections; Male; Middle Aged; Phenol; Stella

2020
Epicardial Interventions: Impact of Liposomal Bupivacaine on Postprocedural Management (The EPI-LIBRE Study).
    Circulation. Arrhythmia and electrophysiology, 2020, Volume: 13, Issue:7

    Topics: Aged; Anesthetics, Local; Atrial Appendage; Atrial Fibrillation; Bupivacaine; Cardiac Surgical Proce

2020
Bupivacaine Toxicity Increases Transmural Dispersion of Repolarization, Developing of a Brugada-like Pattern and Ventricular Arrhythmias, Which is Reversed by Lipid Emulsion Administration. Study in an Experimental Porcine Model.
    Cardiovascular toxicology, 2019, Volume: 19, Issue:5

    Topics: Action Potentials; Anesthetics, Local; Animals; Antidotes; Brugada Syndrome; Bupivacaine; Fat Emulsi

2019
[Treatment of a patient with refractory cardiac arrhythmias using stellate ganglion block. Access by the classical and ultrasound-guided approach].
    Revista espanola de anestesiologia y reanimacion, 2014, Volume: 61, Issue:8

    Topics: Atrioventricular Node; Autonomic Nerve Block; Bupivacaine; Cardiovascular Agents; Catheters, Indwell

2014
Case discussion and root cause analysis: bupivacaine overdose in an infant leading to ventricular tachycardia.
    Anesthesia and analgesia, 2014, Volume: 119, Issue:1

    Topics: Anesthetics, Local; Bupivacaine; Drug Overdose; Humans; Infant; Male; Root Cause Analysis; Tachycard

2014
Autonomic Modulation for the Treatment of Ventricular Arrhythmias: Therapeutic Use of Percutaneous Stellate Ganglion Blocks.
    Journal of cardiovascular electrophysiology, 2017, Volume: 28, Issue:4

    Topics: Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Electrocardiography; Heart; Heart Failure; H

2017
Resuscitation strategies from bupivacaine-induced cardiac arrest.
    Paediatric anaesthesia, 2012, Volume: 22, Issue:2

    Topics: Anesthetics, Local; Animals; Blood Gas Analysis; Blood Pressure; Bupivacaine; Cardiopulmonary Resusc

2012
The relative toxicity of amitriptyline, bupivacaine, and levobupivacaine administered as rapid infusions in rats.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:1

    Topics: Amitriptyline; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Bupiva

2003
Use of thoracic epidural anesthesia for management of electrical storm: a case report.
    Heart rhythm, 2005, Volume: 2, Issue:12

    Topics: Aged; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Catheter Ablation; Humans; Male; Tachyc

2005
Antiarrhythmic effects of targeted cardiac neuromodulation: is it time for clinical application?
    Heart rhythm, 2005, Volume: 2, Issue:12

    Topics: Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Heart; Humans; Sympathetic Nervous System; Ta

2005
Ventricular tachycardia and brief cardiovascular collapse in two infants after caudal anesthesia using a bupivacaine-epinephrine solution.
    Anesthesiology, 1993, Volume: 79, Issue:5

    Topics: Anesthesia, Caudal; Bupivacaine; Epinephrine; Female; Heart Arrest; Humans; Infant; Male; Tachycardi

1993
Toxicity of bupivacaine encapsulated into liposomes and injected intravenously: comparison with plain solutions.
    Anesthesia and analgesia, 1993, Volume: 76, Issue:3

    Topics: Animals; Bupivacaine; Drug Carriers; Heart Arrest; Infusions, Intravenous; Liposomes; Rabbits; Seizu

1993
Epinephrine dysrhythmogenicity is not enhanced by subtoxic bupivacaine in dogs.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:1

    Topics: Anesthetics, Local; Animals; Bupivacaine; Dogs; Electrocardiography; Epinephrine; Tachycardia, Ventr

1996
Intravascular migration of epidural catheter during cesarean section.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:6

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Bupivacaine; Catheterizati

1996
Ventricular arrhythmias with or without programmed electrical stimulation after incremental overdosage with lidocaine, bupivacaine, levobupivacaine, and ropivacaine.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Cardiac Pacing, Artificial; Dogs; Drug Overdose; L

2000