bupivacaine and Surgical Incision

bupivacaine has been researched along with Surgical Incision in 15 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Research

Studies (15)

Authors

Clinical Trials (5)

Trial Overview

Trial Outcomes

Hospital Readmission

Readmission to hospital will be noted (NCT03270514)
Timeframe: From end of surgery assessed up to 30 days post-operatively

Mortality

Mortality will be noted at specific timepoints (NCT03270514)
Timeframe: From end of surgery assessed up to 30 days post-operatively

Non-invasive Ventilation (NIV) Requirement

Episodes of NIV such as upper airway masks or similar devices will be quantified (NCT03270514)
Timeframe: From time of end of surgery to 72 hours post-operatively or until hospital discharge

Patient Satisfaction

Patient will give an assessment regarding pain management on a scale of 0 - 10 with 0 indicating the lowest satisfaction with pain management and 10 indicating the highest satisfaction with pain management (NCT03270514)
Timeframe: Given at the time of discharge up to 30 days post-operatively

Patient Time to Mobilization

The time it takes until patient ambulates will be measured (NCT03270514)
Timeframe: From time of end of surgery to time of mobilization up to 72 hours or discharge, *assessed up to 120 hours*

Patient Time to Oral Intake

The time it takes until the patient is able to/medically cleared to consume food or liquid will be measured (NCT03270514)
Timeframe: From time of end of surgery to time of oral intake up to 72 hours post-operatively or until hospital discharge

Patient Time to Out of Bed to Chair

The time it takes until the patient advances from bedrest to out of bed (OOB) to chair will be measured (NCT03270514)
Timeframe: From time of end of surgery to time of mobilization up to 72 hours post-operatively

Post-operative Nausea and Vomiting

Whether a patient experiences at least one episode of nausea and emesis will be measured (NCT03270514)
Timeframe: From time of end of surgery to 72 hours post-operatively

Re-intubation

Instances of re-intubation will be recorded (NCT03270514)
Timeframe: From time of end of surgery to patient discharge up to one week

Time to Extubation

The time it takes until the patient is extubated post-operatively will be measured (NCT03270514)
Timeframe: From the end of surgery until the patient is extubated up to 72 hours post-operatively

Use of Incentive Spirometry

Frequency of incentive spirometry will be measured (NCT03270514)
Timeframe: From time of end of surgery to 72 hours post-operatively

Length of Hospital and ICU Stay

Length of both hospital and ICU stay will be measured (NCT03270514)
Timeframe: From date of surgery assessed up to 30 day post-operatively

Post-operative Pain Intensity

Postoperative pain scores evaluated by numeric rating scale or (NRS) where 0- no pain and 10- worst pain, at rest and at movement (NCT03270514)
Timeframe: NRS scores will be evaluated every 4 hours until 24 hours post-operatively, every 8 hours until 48 hours post-operatively, and every 12 hours for 72 hours post-operatively

Serum Cortisol Levels

Stress response suppression as a result of treatment will be evaluated by comparing hormone levels between the groups. Serum cortisol levels will be taken to measure this. (NCT03270514)
Timeframe: Measured 8, 48, and 72 hours post-operatively

Total Narcotic Consumption

All narcotics administered in the first 0-8, 8-24, 24-48, and 48-72 hours and the total narcotics administered in the 0-72 hours postoperative period(PCA narcotics, nurse-administered IV narcotics, and oral narcotics). All narcotics will be converted to total IV morphine equivalent for comparison between two groups. (NCT03270514)
Timeframe: 0-72 hours post-operative period

In-hospital Antiemetic Use

Amount of ondansetron patient required postoperatively during hospital stay, in milligrams (NCT03638635)
Timeframe: Time of transfer to post operative suite to time of discharge (usually up to 4 days after surgery).

Length of Stay

Total postoperative hospital stay in days (NCT03638635)
Timeframe: Date of surgery to date of discharge (usually up to 4 days after surgery).

Pain Score

Recorded on a scale of 0 (No pain) to 10 (Worst possible pain) (NCT03638635)
Timeframe: Approximately every 6 hours through postoperative day 3 by 1 pm

Time to Clear Liquid Diet

Number of days from time of surgery until patient tolerates clear liquid diet (NCT03638635)
Timeframe: From time of surgery until first time patient tolerates clear liquids without nausea or vomiting. Assessed until date of discharge (usually up to 4 days after surgery).

Time to Low Fiber Diet

Number of days from day of surgery until patient tolerates low fiber diet (NCT03638635)
Timeframe: From time of surgery until first time patient tolerates a low fiber diet without nausea or vomiting. Assessed until date of discharge (usually up to 4 days after surgery).

Time to Patient Mobilization

Number of days from day of surgery until patient mobilization (NCT03638635)
Timeframe: From time of surgery until time of first patient ambulation post op. Assessed until date of discharge (usually up to 4 days after surgery).

Time to Return of Bowel Function

Number of days from time of surgery until return of bowel function (NCT03638635)
Timeframe: From time of surgery until first time patient passes gas or stool per rectum or into ostomy bag. Assessed until date of discharge (usually up to 4 days after surgery).

Reviews

1 review available for bupivacaine and Surgical Incision

Trials

7 trials available for bupivacaine and Surgical Incision

Other Studies

7 other studies available for bupivacaine and Surgical Incision