Compounds > bupivacaine
Page last updated: 2024-10-24

bupivacaine and Scrotal Hydrocele

bupivacaine has been researched along with Scrotal Hydrocele in 5 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Research Excerpts

ExcerptRelevanceReference
"The addition of 2μg/kg of dexmedetomidine reduced the minimum local anesthetic concentration of bupivacaine used for a TAP block and improved postoperative analgesia in children undergoing surgery for inguinal hernia repair or hydrocelectomy."5.24Dexmedetomidine decreases the required amount of bupivacaine for ultrasound-guided transversus abdominis plane block in pediatrics patients: a randomized study. ( Alia, DA; El Metainy, SA; Raof, RA; Wahab, MA, 2017)
"Current knowledge on local anesthetic dosage for the TAP block in pediatric patients is very limited."2.80Dose effect of local anesthetics on analgesic outcomes for the transversus abdominis plane (TAP) block in children: a randomized, double-blinded, clinical trial. ( De Oliveira, GS; Suresh, S; Taylor, LJ, 2015)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Suresh, S1
Taylor, LJ1
De Oliveira, GS1
Raof, RA1
El Metainy, SA1
Alia, DA1
Wahab, MA1
Joshi, W1
Connelly, NR1
Freeman, K1
Reuben, SS1
Willschke, H1
Marhofer, P1
Bösenberg, A1
Johnston, S1
Wanzel, O1
Cox, SG1
Sitzwohl, C1
Kapral, S1
Trotter, C1
Martin, P1
Youngson, G1
Johnston, G1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ropivacaine Plasma Concentrations and Pharmacokinetics Following Erector Spinae Plane Block in the Pediatric Population[NCT04298099]Phase 424 participants (Anticipated)Interventional2020-12-17Recruiting
Efficacy of Adding Dexmedetomidine Versus Ibuprofen as an Adjuvant to Intraperitoneal Bupivacaine for Pain Control After Laparoscopic Gynecological Procedures: a Double-blind Randomized Comparative Study[NCT06046105]Phase 2/Phase 3180 participants (Anticipated)Interventional2023-09-15Not yet recruiting
Ilioinguinal/Iliohypogastric vs. Quadratus Lumborum Nerve Blockade for Elective Open Inguinal Herniorrhaphy[NCT03007966]Phase 260 participants (Actual)Interventional2017-01-30Completed
A Comparison Of Ultrasound and Predetermined Distance Techniques For Paravertebral Space Localization In Breast Surgery: A Randomized Prospective Trial[NCT01217593]60 participants (Anticipated)Interventional2010-10-31Recruiting
Study of Analgesic Efficacy of Different Kinds of Nerve Blocks on Otoplastic Surgery[NCT04192708]Phase 4144 participants (Anticipated)Interventional2020-02-17Recruiting
A New Approach to Ilio-inguinal Nerve Blocks: 3-layer Injection vs Conventional Ultrasound-guided Single-shot Approach[NCT01625780]32 participants (Actual)Interventional2012-04-30Terminated (stopped due to Not a significant difference in outcomes between groups)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Presence of Opioid Related Side Effects--Itching

(NCT03007966)
Timeframe: 24 hrs Post Nerve Block

InterventionParticipants (Count of Participants)
Ilioinguinal / Iliohypogastric Block2
Quadratus Lumborum Block3

Number of Participants With Presence of Opioid Related Side Effects--Itching

(NCT03007966)
Timeframe: 8 hrs Post Nerve Block

InterventionParticipants (Count of Participants)
Ilioinguinal / Iliohypogastric Block0
Quadratus Lumborum Block4

Number of Participants With Presence of Opioid Related Side Effects--Nausea

(NCT03007966)
Timeframe: 24 hrs Post Nerve Block

InterventionParticipants (Count of Participants)
Ilioinguinal / Iliohypogastric Block6
Quadratus Lumborum Block3

Number of Participants With Presence of Opioid Related Side Effects--Nausea

(NCT03007966)
Timeframe: 8 hrs Post Nerve Block

InterventionParticipants (Count of Participants)
Ilioinguinal / Iliohypogastric Block9
Quadratus Lumborum Block5

Number of Participants With Presence of Opioid Related Side Effects--Vomiting

(NCT03007966)
Timeframe: 24 hrs Post Nerve Block

InterventionParticipants (Count of Participants)
Ilioinguinal / Iliohypogastric Block3
Quadratus Lumborum Block2

Number of Participants With Presence of Opioid Related Side Effects--Vomiting

(NCT03007966)
Timeframe: 8 hrs Post Nerve Block

InterventionParticipants (Count of Participants)
Ilioinguinal / Iliohypogastric Block3
Quadratus Lumborum Block3

Post-operative Verbal Pain Score at Rest

Assessed on an 11 point (0-10) numeric analog scale with a higher score denoting a worse outcome (NCT03007966)
Timeframe: 24 hrs Post Nerve Block

Interventionscore on a scale (Mean)
Ilioinguinal / Iliohypogastric Block3
Quadratus Lumborum Block2.7

Post-operative Verbal Pain Score at Rest

Assessed on an 11-point (0-10) numeric analog scale with a higher score denoting a worse outcome (NCT03007966)
Timeframe: 8 hrs Post Nerve Block

Interventionscore on a scale (Mean)
Ilioinguinal / Iliohypogastric Block3.6
Quadratus Lumborum Block3.3

Post-operative Verbal Pain Score With Activity

Assessed on an 11 point (0-10) numeric analog scale with a higher score denoting a worse outcome (NCT03007966)
Timeframe: 24hrs Post Nerve Block

Interventionscore on a scale (Mean)
Ilioinguinal / Iliohypogastric Block4.9
Quadratus Lumborum Block5.3

Post-operative Verbal Pain Score With Movement

Assessed on an 11-point (0-10) numeric analog scale with a higher score denoting a worse outcome. (NCT03007966)
Timeframe: 8 hrs Post Nerve Block

Interventionscore on a scale (Mean)
Ilioinguinal / Iliohypogastric Block5.10
Quadratus Lumborum Block5.03

Time to First Oral Analgesic

When does the patient require their first post operative analgesic dose? (NCT03007966)
Timeframe: 24hrs Post Nerve Block

Interventionminutes (Median)
Ilioinguinal / Iliohypogastric Block141
Quadratus Lumborum Block91

Total Opioid Consumption

Total opioids consumed during the first 24hrs post operatively. Measured as 24hr Oxycodone Equivalent (NCT03007966)
Timeframe: 24 hrs Post Nerve Block

Interventionmilligrams (Mean)
Ilioinguinal / Iliohypogastric Block19.7
Quadratus Lumborum Block25.2

Trials

5 trials available for bupivacaine and Scrotal Hydrocele

ArticleYear
Dose effect of local anesthetics on analgesic outcomes for the transversus abdominis plane (TAP) block in children: a randomized, double-blinded, clinical trial.
    Paediatric anaesthesia, 2015, Volume: 25, Issue:5

    Topics: Abdomen; Adult; Analgesia; Anesthetics, Local; Bupivacaine; Dose-Response Relationship, Drug; Double

2015
Dexmedetomidine decreases the required amount of bupivacaine for ultrasound-guided transversus abdominis plane block in pediatrics patients: a randomized study.
    Journal of clinical anesthesia, 2017, Volume: 37

    Topics: Abdominal Muscles; Adrenergic alpha-2 Receptor Agonists; Anesthetics, Local; Blood Pressure; Bupivac

2017
Analgesic effect of clonidine added to bupivacaine 0.125% in paediatric caudal blockade.
    Paediatric anaesthesia, 2004, Volume: 14, Issue:6

    Topics: Adrenergic alpha-Agonists; Analgesics; Anesthesia, Caudal; Anesthetics, Local; Bupivacaine; Child, P

2004
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children.
    British journal of anaesthesia, 2005, Volume: 95, Issue:2

    Topics: Ambulatory Surgical Procedures; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child; Crypt

2005
A comparison between ilioinguinal-iliohypogastric nerve block performed by anaesthetist or surgeon for postoperative analgesia following groin surgery in children.
    Paediatric anaesthesia, 1995, Volume: 5, Issue:6

    Topics: Analgesia; Anesthesia, General; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Cryptorchi

1995