Page last updated: 2024-10-24

bupivacaine and Retinal Diseases

bupivacaine has been researched along with Retinal Diseases in 13 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Retinal Diseases: Diseases involving the RETINA.

Research Excerpts

ExcerptRelevanceReference
"The efficacy of anaesthesia, degree of postoperative pain and intraoperative and postoperative complications were recorded."2.84A prospective, randomised, double-masked comparison of local anaesthetic agents for vitrectomy. ( Tong, Y; Wang, YX; Wang, ZY; Zhao, PQ; Zhou, YL, 2017)
"Dexmedetomidine is a useful and safe drug in combination with lignocaine bupivacaine in peribulbar for vitreoretinal surgery as it maintains hemodynamic stability and provides sedation, which enables full cooperation and potentially better operating conditions."1.51Evaluation of the effect and safety of dexmedetomidine as an additive to local anesthesia in peribulbar block for vitreoretinal surgery. ( Agarwal, M; Gautam, P; Gujral, GS; Shrivastav, A; Singh, S, 2019)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (23.08)18.2507
2000's7 (53.85)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gujral, GS1
Agarwal, M1
Gautam, P1
Shrivastav, A1
Singh, S1
Ituk, US1
McCoy, DM1
Zhou, YL1
Tong, Y1
Wang, YX1
Zhao, PQ1
Wang, ZY1
Calenda, E3
Quintyn, JC2
Brasseur, G3
Muraine, M2
Ghosh, YK1
Goodall, KL1
Bahçecioglu, H1
Unal, M1
Artunay, O1
Rasier, R1
Sarici, A1
Benedetti, S1
Agostini, A1
Kwok, AK1
Van Newkirk, MR1
Lam, DS1
Fan, DS1
Li, HK1
Abouleish, A1
Grady, J1
Groeschel, W1
Gill, KS1
Olle, P1
Sharma, T1
Gopal, L1
Shanmugam, MP1
Bhende, P1
George, J1
Samanta, TK1
Mukesh, BN1
Friedberg, MA1
Spellman, FA1
Pilkerton, AR1
Perraut, LE1
Stephens, RF1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Influence of SPI-guided Analgesia With Preventive Different Peribulbar Blocks (PBB) on the Presence of OCR, Postoperative Pain, PONV in Patients Undergoing VRS Under General Anaesthesia: a Randomised, Controlled Trial[NCT03413371]175 participants (Anticipated)Interventional2018-04-26Recruiting
Influence of Surgical Pleth Index-guided Analgesia Using Different Techniques on the Perioperative Outcomes in Patients Undergoing Vitreoretinal Surgery Under General Anaesthesia: Randomised, Controlled Trial[NCT02973581]176 participants (Actual)Interventional2016-02-29Completed
A Prospective, Randomised, Single-masked Comparison of Retrobulbar Anesthesia, Peribulbar Anesthesia and Topical Combined Subconjunctival(Two-step) Anesthesia in Posterior Vitrectomy[NCT03577574]90 participants (Anticipated)Interventional2018-08-02Recruiting
A Randomized Trial of Buffered vs Nonbuffered Lidocaine With Epinephrine for Cervical Loop Excision[NCT01405768]Phase 256 participants (Actual)Interventional2011-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Injection Pain Score (Mean)

"A Likert visual analog scale will be used to document each study participant's level of pain experienced during injection of the cervical block.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of procedure

Interventionunits on a scale (Mean)
Lidocaine Arm25
Buffered Lidocaine19

Injection Pain Score (Median)

"A Likert visual analog scale will be used to document each study participant's level of pain experienced during injection of the cervical block.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of the procedure

Interventionunits on a scale (Median)
Lidocaine Arm26
Buffered Lidocaine18

Overall LEEP Procedure Pain Including Procedural Pain and Cramping (Mean)

"A Likert visual analog scale will be used to determine the overall pain experienced by each study participant including injection pain, procedural pain, and cramping.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of procedure

,
Interventionunits on a scale (Mean)
Injection painProcedure painCramping pain
Buffered Lidocaine191918
Lidocaine Arm252719

Overall LEEP Procedure Pain Including Procedural Pain and Cramping (Median)

"A Likert visual analog scale will be used to determine the overall pain experienced by each study participant including injection pain, procedural pain, and cramping.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of procedure

,
Interventionunits on a scale (Median)
Injection painProcedure painCramping pain
Buffered Lidocaine181314
Lidocaine Arm262519

Trials

4 trials available for bupivacaine and Retinal Diseases

ArticleYear
A prospective, randomised, double-masked comparison of local anaesthetic agents for vitrectomy.
    The British journal of ophthalmology, 2017, Volume: 101, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amides; Anesthetics, Combined; Anesthetics, Local; Bupiv

2017
Sub-Tenon infiltration or classical analgesic drugs to relieve postoperative pain.
    Clinical & experimental ophthalmology, 2004, Volume: 32, Issue:2

    Topics: Adult; Analgesia; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Connective Tissue; Double-Bli

2004
Postoperative pain relief in vitreoretinal surgery with subtenon Bupivacaine 0.75%.
    Acta ophthalmologica Scandinavica, 2005, Volume: 83, Issue:1

    Topics: Analgesia; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Connective Tissue; Double-Blind Metho

2005
Comparison of pH-adjusted bupivacaine with a mixture of non-pH-adjusted bupivacaine and lignocaine in primary vitreoretinal surgery.
    Retina (Philadelphia, Pa.), 2002, Volume: 22, Issue:2

    Topics: Alkalies; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Double-Blind Me

2002

Other Studies

9 other studies available for bupivacaine and Retinal Diseases

ArticleYear
Evaluation of the effect and safety of dexmedetomidine as an additive to local anesthesia in peribulbar block for vitreoretinal surgery.
    Indian journal of ophthalmology, 2019, Volume: 67, Issue:5

    Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Anesthesia, Local; Anesthetics, Local

2019
Catecholamine-induced cardiomyopathy: a complication following a retrobulbar block.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2014, Volume: 49, Issue:2

    Topics: Anesthetics, Local; Bupivacaine; Cardiomyopathies; Cardiotonic Agents; Continuous Positive Airway Pr

2014
Peribulbar anaesthesia using a combination of lidocaine, bupivocaine and clonidine in vitreoretinal surgery.
    Indian journal of ophthalmology, 2002, Volume: 50, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anesthesia, Local; Anesthetics, Combined; Anesthetics, L

2002
Peribulbar anaesthesia using a combination of lidocaine, bupivocaine and clonidine in vitreoretinal surgery.
    Indian journal of ophthalmology, 2002, Volume: 50, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anesthesia, Local; Anesthetics, Combined; Anesthetics, L

2002
Peribulbar anaesthesia using a combination of lidocaine, bupivocaine and clonidine in vitreoretinal surgery.
    Indian journal of ophthalmology, 2002, Volume: 50, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anesthesia, Local; Anesthetics, Combined; Anesthetics, L

2002
Peribulbar anaesthesia using a combination of lidocaine, bupivocaine and clonidine in vitreoretinal surgery.
    Indian journal of ophthalmology, 2002, Volume: 50, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anesthesia, Local; Anesthetics, Combined; Anesthetics, L

2002
Posterior vitrectomy under topical anesthesia.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2007, Volume: 42, Issue:2

    Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Local;

2007
Posterior vitrectomy under topical anesthesia.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2007, Volume: 42, Issue:2

    Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Local;

2007
Posterior vitrectomy under topical anesthesia.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2007, Volume: 42, Issue:2

    Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Local;

2007
Posterior vitrectomy under topical anesthesia.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2007, Volume: 42, Issue:2

    Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Local;

2007
Peribulbar anesthesia in vitreoretinal surgery.
    Retina (Philadelphia, Pa.), 1994, Volume: 14, Issue:3

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Bupivacaine; Drug Combinations; Humans; Hyaluronoglucosa

1994
Sub-Tenon's anesthesia in vitreoretinal surgery: a needleless technique.
    Retina (Philadelphia, Pa.), 1999, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Conn

1999
Sub-Tenon's injection for local anesthesia in posterior segment surgery.
    Ophthalmology, 2000, Volume: 107, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupiva

2000
Peribulbar anesthesia and sub-Tenon injection for vitreoretinal surgery: 300 cases.
    Acta ophthalmologica Scandinavica, 2000, Volume: 78, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesia; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Lo

2000
Peribulbar anesthesia and sub-Tenon injection for vitreoretinal surgery: 300 cases.
    Acta ophthalmologica Scandinavica, 2000, Volume: 78, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesia; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Lo

2000
Peribulbar anesthesia and sub-Tenon injection for vitreoretinal surgery: 300 cases.
    Acta ophthalmologica Scandinavica, 2000, Volume: 78, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesia; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Lo

2000
Peribulbar anesthesia and sub-Tenon injection for vitreoretinal surgery: 300 cases.
    Acta ophthalmologica Scandinavica, 2000, Volume: 78, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesia; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Lo

2000
An alternative technique of local anesthesia for vitreoretinal surgery.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1991, Volume: 109, Issue:11

    Topics: Anesthesia, Local; Bupivacaine; Humans; Hyaluronoglucosaminidase; Mepivacaine; Orbit; Retinal Diseas

1991