Page last updated: 2024-10-24

bupivacaine and Reperfusion Injury

bupivacaine has been researched along with Reperfusion Injury in 6 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"These data confirm that TIVA with propofol attenuates oxidative stress related to tourniquet-induced ischaemia-reperfusion injury in children."5.17Tourniquet-induced ischemia-reperfusion injuries during extremity surgery at children's age: impact of anesthetic chemical structure. ( Budic, I; Cvetkovic, T; Jevtovic-Stoimenov, T; Kitic, D; Kocic, G; Pavlovic, D; Simic, D, 2013)
" In this study, we investigated the effects of epidural bupivacaine on hepatic ischemia reperfusion injury in a rat model."3.83The effects of epidural bupivacaine on ischemia/reperfusion-induced liver injury. ( Bagriacik, U; Bedirli, N; Bozkirli, F; Sarikus, Z; Yilmaz, G, 2016)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Koşucu, M1
Coşkun, I1
Eroglu, A1
Kutanis, D1
Menteşe, A1
Karahan, SC1
Baki, E1
Kerimoğlu, S1
Topbas, M1
Li, X1
Huo, X1
Zhang, C1
Ma, X1
Han, F1
Wang, G1
Sarikus, Z1
Bedirli, N2
Yilmaz, G1
Bagriacik, U1
Bozkirli, F1
Akyürek, N1
Kurtipek, O1
Kavutcu, M1
Kartal, S1
Bayraktar, AC1
Budic, I1
Pavlovic, D1
Kitic, D1
Kocic, G1
Cvetkovic, T1
Simic, D1
Jevtovic-Stoimenov, T1
Lee, HT1
Krichevsky, IE1
Xu, H1
Ota-Setlik, A1
D'Agati, VD1
Emala, CW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clonidine for Tourniquet-related Pain in Children: A Pilot Study[NCT04564430]Phase 420 participants (Anticipated)Interventional2021-03-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for bupivacaine and Reperfusion Injury

ArticleYear
The effects of spinal, inhalation, and total intravenous anesthetic techniques on ischemia-reperfusion injury in arthroscopic knee surgery.
    BioMed research international, 2014, Volume: 2014

    Topics: Acetaminophen; Adolescent; Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesia, Spina

2014
Tourniquet-induced ischemia-reperfusion injuries during extremity surgery at children's age: impact of anesthetic chemical structure.
    Redox report : communications in free radical research, 2013, Volume: 18, Issue:1

    Topics: Adolescent; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Inhalation; Antioxidants;

2013

Other Studies

4 other studies available for bupivacaine and Reperfusion Injury

ArticleYear
Role of continuous high thoracic epidural anesthesia in hippocampal apoptosis after global cerebral ischemia in rats.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2014, Volume: 34, Issue:4

    Topics: Anesthesia, Epidural; Anesthetics, Local; Animals; Apoptosis; bcl-2-Associated X Protein; Brain Isch

2014
The effects of epidural bupivacaine on ischemia/reperfusion-induced liver injury.
    Bratislavske lekarske listy, 2016, Volume: 117, Issue:1

    Topics: Anesthesia, Epidural; Anesthetics, Local; Animals; Bupivacaine; Liver; Rats; Reperfusion Injury

2016
Thoracic epidural bupivacaine attenuates inflammatory response, intestinal lipid peroxidation, oxidative injury, and mucosal apoptosis induced by mesenteric ischemia/reperfusion.
    Anesthesia and analgesia, 2011, Volume: 113, Issue:5

    Topics: Anesthesia, Epidural; Anesthetics, Local; Animals; Apoptosis; Bupivacaine; Catalase; Catheterization

2011
Local anesthetics worsen renal function after ischemia-reperfusion injury in rats.
    American journal of physiology. Renal physiology, 2004, Volume: 286, Issue:1

    Topics: Anesthetics, Local; Animals; Apoptosis; Blood Pressure; Bupivacaine; Gene Expression; Heart Rate; In

2004