bupivacaine has been researched along with Rectal Diseases in 10 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Rectal Diseases: Pathological developments in the RECTUM region of the large intestine (INTESTINE, LARGE).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The study measured postoperative pain scores and opioid requirements." | 1.46 | Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery. ( Adhikary, SD; Choi, CS; Hollenbeak, CS; Messaris, E; Puleo, FJ; Quintili, A; Stokes, AL, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peterson, KJ | 1 |
| Dyrud, P | 1 |
| Johnson, C | 1 |
| Blank, JJ | 1 |
| Eastwood, DC | 1 |
| Butterfield, GE | 1 |
| Stekiel, TA | 1 |
| Peterson, CY | 1 |
| Ludwig, KA | 1 |
| Ridolfi, TJ | 1 |
| Ladha, A | 1 |
| Garg, P | 1 |
| Puranik, C | 1 |
| Keller, DS | 1 |
| Stulberg, JJ | 1 |
| Lawrence, JK | 1 |
| Delaney, CP | 2 |
| Stokes, AL | 1 |
| Adhikary, SD | 1 |
| Quintili, A | 1 |
| Puleo, FJ | 1 |
| Choi, CS | 1 |
| Hollenbeak, CS | 1 |
| Messaris, E | 1 |
| Stuhldreher, JM | 1 |
| Adamina, M | 1 |
| Konopacka, A | 1 |
| Brady, K | 1 |
| Buyukkocak, U | 1 |
| Daphan, C | 1 |
| Caglayan, O | 1 |
| Aydinuraz, K | 1 |
| Kaya, T | 1 |
| Saygun, O | 1 |
| Agalar, F | 1 |
| Baumgarten, RK | 1 |
| Courtice, ID | 1 |
| MacLeod, BA | 1 |
| Chamberlain, DP | 1 |
| Crawford, RD | 1 |
| Clery, AP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Bilateral Mid-Abdominal Transverse Abdominis Plane and Rectus Sheath Blocks Comparing The Use of Liposomal Bupivacaine/Bupivacaine vs. Regular Bupivacaine in Laparoscopic Colectomy Procedures.[NCT05224089] | Phase 4 | 114 participants (Anticipated) | Interventional | 2022-04-27 | Recruiting | ||
| TAP Blocks Performed With Bupivacaine Versus Liposomal Bupivacaine in Colorectal Surgery Patients: A Prospective, Cluster Randomized Trial[NCT03638635] | Phase 4 | 63 participants (Actual) | Interventional | 2018-05-14 | Terminated (stopped due to Lack of personnel available to complete study.) | ||
| "Analgesic Efficacy of Combined Transversus Abdominis Plane Block and Posterior Rectus Sheath Block in Patients Undergoing Laparoscopic Appendectomy"[NCT06088082] | Phase 3 | 100 participants (Anticipated) | Interventional | 2023-10-01 | Active, not recruiting | ||
| Increased Postoperative Opioid Use is a Risk Factor for an Ileus After Laparoscopic Colorectal Surgery---A Case Control Study[NCT05262569] | 596 participants (Actual) | Observational | 2022-04-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Amount of ondansetron patient required postoperatively during hospital stay, in milligrams (NCT03638635)
Timeframe: Time of transfer to post operative suite to time of discharge (usually up to 4 days after surgery).
| Intervention | mg (Mean) |
|---|---|
| Standard Bupivacaine | 2.9 |
| Bupivacaine Liposome | 5.6 |
Total postoperative hospital stay in days (NCT03638635)
Timeframe: Date of surgery to date of discharge (usually up to 4 days after surgery).
| Intervention | days (Median) |
|---|---|
| Standard Bupivacaine | 3 |
| Bupivacaine Liposome | 3.5 |
Recorded on a scale of 0 (No pain) to 10 (Worst possible pain) (NCT03638635)
Timeframe: Approximately every 6 hours through postoperative day 3 by 1 pm
| Intervention | units on a scale (Median) |
|---|---|
| Standard Bupivacaine | 3 |
| Bupivacaine Liposome | 3 |
Number of days from time of surgery until patient tolerates clear liquid diet (NCT03638635)
Timeframe: From time of surgery until first time patient tolerates clear liquids without nausea or vomiting. Assessed until date of discharge (usually up to 4 days after surgery).
| Intervention | days (Median) |
|---|---|
| Standard Bupivacaine | 0 |
| Bupivacaine Liposome | 0 |
Number of days from day of surgery until patient tolerates low fiber diet (NCT03638635)
Timeframe: From time of surgery until first time patient tolerates a low fiber diet without nausea or vomiting. Assessed until date of discharge (usually up to 4 days after surgery).
| Intervention | days (Median) |
|---|---|
| Standard Bupivacaine | 1.5 |
| Bupivacaine Liposome | 1 |
Number of days from day of surgery until patient mobilization (NCT03638635)
Timeframe: From time of surgery until time of first patient ambulation post op. Assessed until date of discharge (usually up to 4 days after surgery).
| Intervention | days (Median) |
|---|---|
| Standard Bupivacaine | 1 |
| Bupivacaine Liposome | 0.5 |
Number of days from time of surgery until return of bowel function (NCT03638635)
Timeframe: From time of surgery until first time patient passes gas or stool per rectum or into ostomy bag. Assessed until date of discharge (usually up to 4 days after surgery).
| Intervention | days (Median) |
|---|---|
| Standard Bupivacaine | 2 |
| Bupivacaine Liposome | 2 |
1 trial available for bupivacaine and Rectal Diseases
| Article | Year |
|---|---|
Effects of different anesthetic techniques on serum leptin, C-reactive protein, and cortisol concentrations in anorectal surgery.
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Local; Bupivacaine; C-Reactive Protein; Female; Humans; | 2006 |
9 other studies available for bupivacaine and Rectal Diseases
| Article | Year |
|---|---|
Saddle block anesthetic technique for benign outpatient anorectal surgery.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Female; | 2022 |
A simplified easily reproducible pudendal nerve block technique for anorectal surgery (SEPTA) - a video vignette.
Topics: Anus Neoplasms; Bupivacaine; Female; Humans; Male; Nerve Block; Pain Measurement; Pain, Postoperativ | 2018 |
Process control to measure process improvement in colorectal surgery: modifications to an established enhanced recovery pathway.
Topics: Abdominal Muscles; Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivac | 2014 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Liposomal Bupivacaine Use in Transversus Abdominis Plane Blocks Reduces Pain and Postoperative Intravenous Opioid Requirement After Colorectal Surgery.
Topics: Abdominal Muscles; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Effect of local anesthetics on postoperative pain and opioid consumption in laparoscopic colorectal surgery.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Analysis of Variance; | 2012 |
Spinal anesthesia and postoperative urinary retention in patients with benign anorectal disease.
Topics: Anesthesia, Spinal; Anus Diseases; Bupivacaine; Humans; Postoperative Complications; Rectal Diseases | 1994 |
Ischiorectal space block for anorectal surgery.
Topics: Adult; Anesthesia, Local; Anus Diseases; Bupivacaine; Female; Humans; Lidocaine; Male; Pain Measurem | 1990 |
Integrated electromyographic measurement of abdominal motor blockade during bupivacaine epidural anesthesia for lower abdominal and pelvic surgery.
Topics: Abdomen; Anesthesia, Epidural; Bupivacaine; Electromyography; Epinephrine; Female; Herniorrhaphy; Hu | 1987 |
Local anaesthesia containing hyaluronidase and adrenaline for anorectal surgery: experiences with 576 operations.
Topics: Anesthesia, Local; Anus Diseases; Bupivacaine; Epinephrine; Humans; Hyaluronoglucosaminidase; Method | 1973 |