Page last updated: 2024-10-24

bupivacaine and Psychomotor Agitation

bupivacaine has been researched along with Psychomotor Agitation in 6 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Psychomotor Agitation: A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions.

Research Excerpts

ExcerptRelevanceReference
"In children undergoing cleft lip repair surgery, infraorbital nerve block at the beginning of surgery significantly decreased the incidence of EA and the duration of EA, and provided satisfactory postoperative analgesia without delaying the time to extubation with sevoflurane anesthesia."9.20The effect of infraorbital nerve block on emergence agitation in children undergoing cleft lip surgery under general anesthesia with sevoflurane. ( Fu, W; Li, ST; Liu, G; Wang, H, 2015)
"In both acute thermal- and inflammatory-induced pain, intrathecally administered midazolam and bupivacaine produced synergistic analgesia with decreased side effects in intrathecally catheterized rats."7.72Midazolam can potentiate the analgesic effects of intrathecal bupivacaine on thermal- or inflammatory-induced pain. ( Hanaoka, K; Nishiyama, T, 2003)
"In children undergoing cleft lip repair surgery, infraorbital nerve block at the beginning of surgery significantly decreased the incidence of EA and the duration of EA, and provided satisfactory postoperative analgesia without delaying the time to extubation with sevoflurane anesthesia."5.20The effect of infraorbital nerve block on emergence agitation in children undergoing cleft lip surgery under general anesthesia with sevoflurane. ( Fu, W; Li, ST; Liu, G; Wang, H, 2015)
"In both acute thermal- and inflammatory-induced pain, intrathecally administered midazolam and bupivacaine produced synergistic analgesia with decreased side effects in intrathecally catheterized rats."3.72Midazolam can potentiate the analgesic effects of intrathecal bupivacaine on thermal- or inflammatory-induced pain. ( Hanaoka, K; Nishiyama, T, 2003)
"Clonidine has proven to be effective in reducing the incidence of post-operative agitation at a higher dose (3 and 2 μg kg⁻¹)."2.76Efficacy of low-dose caudal clonidine in reduction of sevoflurane-induced agitation in children undergoing urogenital and lower limb surgery: a prospective randomised double-blind study. ( Agarwala, RB; Ghosh, SM; Pandey, M; Vajifdar, H, 2011)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, H1
Liu, G1
Fu, W1
Li, ST1
Al-Zaben, KR1
Qudaisat, IY1
Alja'bari, AN1
Ababneh, OA1
Yousef, AM1
Al-Shudifat, AM1
Saadawy, I1
Boker, A1
Elshahawy, MA1
Almazrooa, A1
Melibary, S1
Abdellatif, AA1
Afifi, W1
Ghosh, SM1
Agarwala, RB1
Pandey, M1
Vajifdar, H1
Nishiyama, T1
Hanaoka, K1
Aono, J1
Mamiya, K1
Manabe, M1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Caudal Bupivacaine Alone With Bupivacaine Plus Two Doses of Dexmedetomidine for Postoperative Analgesia in Pediatric Patients Undergoing Infra-umbilical Surgery: A Randomized Controlled Double Blinded Study[NCT02385435]Phase 2/Phase 391 participants (Actual)Interventional2014-01-31Completed
Addition of Magnesium Sulfate to Caudal for Prevention of Emergence Agitation in Children[NCT02164773]Phase 470 participants (Anticipated)Interventional2013-10-31Recruiting
Use of Handheld Audiovisual Devices to Treat Pediatric Preoperative Anxiety: A Randomized Control Trial.[NCT02286674]200 participants (Actual)Interventional2014-11-30Completed
Effectivity of 0.5 mg/kg Propofol in the End of Anesthesia to Reduce the Incidence of Postanesthetic Emergence Agitation in Pediatric Patients Under General Inhalation Anesthesia[NCT03528954]54 participants (Actual)Interventional2018-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for bupivacaine and Psychomotor Agitation

ArticleYear
The effect of infraorbital nerve block on emergence agitation in children undergoing cleft lip surgery under general anesthesia with sevoflurane.
    Paediatric anaesthesia, 2015, Volume: 25, Issue:9

    Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Bupivac

2015
The effects of caudal or intravenous dexmedetomidine on postoperative analgesia produced by caudal bupivacaine in children: a randomized controlled double-blinded study.
    Journal of clinical anesthesia, 2016, Volume: 33

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Caudal; Anesthetics, Local; Bupivacaine; Child; Ch

2016
Effect of dexmedetomidine on the characteristics of bupivacaine in a caudal block in pediatrics.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:2

    Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Anesthesia, Caudal; Anes

2009
Effect of dexmedetomidine on the characteristics of bupivacaine in a caudal block in pediatrics.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:2

    Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Anesthesia, Caudal; Anes

2009
Effect of dexmedetomidine on the characteristics of bupivacaine in a caudal block in pediatrics.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:2

    Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Anesthesia, Caudal; Anes

2009
Effect of dexmedetomidine on the characteristics of bupivacaine in a caudal block in pediatrics.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:2

    Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Anesthesia, Caudal; Anes

2009
Efficacy of low-dose caudal clonidine in reduction of sevoflurane-induced agitation in children undergoing urogenital and lower limb surgery: a prospective randomised double-blind study.
    European journal of anaesthesiology, 2011, Volume: 28, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Caudal; Anesthetics, Combined; Anesthetics, Inhala

2011

Other Studies

2 other studies available for bupivacaine and Psychomotor Agitation

ArticleYear
Midazolam can potentiate the analgesic effects of intrathecal bupivacaine on thermal- or inflammatory-induced pain.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:5

    Topics: Anesthetics, Intravenous; Anesthetics, Local; Animals; Behavior, Animal; Bupivacaine; Dose-Response

2003
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine

1999
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine

1999
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine

1999
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine

1999