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bupivacaine and Prostatic Neoplasms

bupivacaine has been researched along with Prostatic Neoplasms in 22 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Prostatic Neoplasms: Tumors or cancer of the PROSTATE.

Research Excerpts

ExcerptRelevanceReference
"We assessed the analgesic efficacy of levobupivacaine when administered as an adjuvant to diclofenac sodium in prostate biopsy pain management and effects of prostate biopsy on sexual function."9.14'Multimodal' approach to management of prostate biopsy pain and effects on sexual function: efficacy of levobupivacaine adjuvant to diclofenac sodium - a prospective randomized trial. ( Aktoz, T; Atakan, IH; Inci, O; Kaplan, M; Memis, D; Turan, U, 2010)
"We assessed the analgesic efficacy of levobupivacaine when administered as an adjuvant to diclofenac sodium in prostate biopsy pain management and effects of prostate biopsy on sexual function."5.14'Multimodal' approach to management of prostate biopsy pain and effects on sexual function: efficacy of levobupivacaine adjuvant to diclofenac sodium - a prospective randomized trial. ( Aktoz, T; Atakan, IH; Inci, O; Kaplan, M; Memis, D; Turan, U, 2010)
"These finding suggest that use of PCEA with bupivacaine and fentanyl is more effective in managing pain related to HDR brachytherapy for prostate cancer, and results in a positive patient outcome thereby improving patient satisfaction."5.12Prostate HDR radiation therapy: a comparative study evaluating the effectiveness of pain management with peripheral PCA vs. PCEA. ( Block, M; Colella, J; Galli, B; Gejerman, G; Knorr-Mulder, C; Lanteri, V; Levey, S; Sawczuk, I; Scheuch, J; Scrofine, S; Siegel, A; Watson, R, 2006)
" We present the case of the youngest reported child to have received intrathecal analgesia for terminal care: a 3-year-old boy with advanced pelvic rhabdomyosarcoma, whose refractory pain was managed effectively with an intrathecal infusion of bupivacaine and preservative-free clonidine."3.78Intrathecal infusion of bupivacaine and clonidine provides effective analgesia in a terminally ill child. ( Lauder, G; Whyte, E, 2012)
"The management of Prostate cancer (PC), since PSA testing has been introduced in the clinical practice, has been significantly spoiled by a "leading-time bias" effect."1.35Transrectal-HIFU as primary minimally-invasive option for localized prostate cancer. Is spinal anaesthesia cost-effective? A single centre experience in over 100 patients. ( Citro, R; Collura, D; D'Urso, L; Grassano, MT; Grosso, P; Guglielminotti, E; Guglielmotti, E; Macchiarulo, R; Muto, G; Rivalta, L; Valz, C, 2009)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.55)18.2507
2000's9 (40.91)29.6817
2010's11 (50.00)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Shim, JW1
Cho, YJ1
Moon, HW1
Park, J1
Lee, HM1
Kim, YS1
Moon, YE1
Hong, SH1
Chae, MS1
Jose, C1
Hebert-Chatelain, E1
Dias Amoedo, N1
Roche, E1
Obre, E1
Lacombe, D1
Rezvani, HR1
Pourquier, P1
Nouette-Gaulain, K1
Rossignol, R1
Tüfek, A1
Tokgöz, O1
Söylemez, H1
Kristensen, BS2
Fenger-Eriksen, C2
Pedersen, KV2
Felsby, S2
Baumunk, D1
Strang, CM1
Kropf, S1
Schäfer, M1
Schrader, M1
Weikert, S1
Cash, H1
Breckwoldt, J1
Miller, K1
Hachenberg, T1
Schostak, M1
Kucur, M1
Goktas, S1
Kaynar, M1
Apiliogullari, S1
Kilic, O1
Akand, M1
Gul, M1
Celik, JB1
Shaaban, M1
Esa, WA1
Maheshwari, K1
Elsharkawy, H1
Soliman, LM1
Xuan, W1
Zhao, H1
Hankin, J1
Chen, L1
Yao, S1
Ma, D1
Lee, SJ1
Bai, SJ1
Lee, JS1
Kim, WO1
Shin, YS1
Lee, KY1
Cuvas, O2
Er, AE1
Ongen, E1
Basar, H2
Grosso, P1
D'Urso, L1
Collura, D1
Citro, R1
Grassano, MT1
Macchiarulo, R1
Rivalta, L1
Valz, C1
Muto, G1
Guglielmotti, E1
Guglielminotti, E1
Tikuisis, R1
Miliauskas, P1
Samalavicius, NE1
Zurauskas, A1
Sruogis, A1
Aktoz, T1
Kaplan, M1
Turan, U1
Memis, D1
Atakan, IH1
Inci, O1
Yeygel, A1
Turkyilmaz, E1
Sunay, MM1
Whyte, E1
Lauder, G1
Sánchez Zalabardo, JM1
Sánchez Elipe, MA1
Regojo Zapata, O1
Elizalde Benito, A1
Valle Gerhold, J1
López López, JA1
Valdivia Uría, JG1
Lee, YY1
Muchhal, K1
Chan, CK1
Salonia, A1
Crescenti, A1
Suardi, N1
Memmo, A1
Naspro, R1
Bocciardi, AM1
Colombo, R1
Da Pozzo, LF1
Rigatti, P1
Montorsi, F1
Salomäki, TE1
Laurila, PA1
Ville, J1
Colella, J1
Scrofine, S1
Galli, B1
Knorr-Mulder, C1
Gejerman, G1
Scheuch, J1
Lanteri, V1
Siegel, A1
Levey, S1
Watson, R1
Block, M1
Sawczuk, I1
Zeisser, M1
Robillart, A1
Perrot, G1
Jacqmin, D1
Grattard, C1
Gros, H1
Dupeyron, JP1
Bollack, C1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Ultrasound-Guided Quadratus Lumborum Block and Epidural Analgesia for Postoperative Pain Management After Renal Transplantation[NCT03771339]50 participants (Actual)Interventional2018-12-10Completed
Effect of Bilateral Quadratus Lumborum Block for Pain Relief in Patients With Cesarean Section[NCT03199170]90 participants (Actual)Interventional2017-09-01Completed
Addition of Lidocaine to Levobupivacaine Reduces Intrathecal Block Duration: Randomized Controlled Trial[NCT01675895]Phase 440 participants (Actual)Interventional2009-07-31Completed
A Comparison of the Recovery Profiles of Bupivacaine or Bupivacaine Mixed With Lidocaine Spinal Anesthesia and Local Infiltration Anesthesia for Outpatient Herniorrhaphy[NCT01548794]Phase 493 participants (Actual)Interventional2012-03-31Completed
Comparison of Intratechal Low-Dose Levobupivacaine With Levobupivacaine-Fentanyl and Levobupivacaine-Sufentanil Combinations for Cesarean Section[NCT02430090]Phase 245 participants (Actual)Interventional2006-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Adverse Events as a Measure of Safety and Tolerability

The frequency and the severity (ex) of the side effects including nausea and vomiting, hypotension, pruritus, and bradycardia were recorded. (NCT02430090)
Timeframe: Up to 4 months

Interventionparticipants (Number)
Levobupivacaine5
Levobupivacaine + Fentanyl10
Levobupivacaine + Sufentanil9

Trials

12 trials available for bupivacaine and Prostatic Neoplasms

ArticleYear
Analgesic efficacy of intrathecal morphine and bupivacaine during the early postoperative period in patients who underwent robotic-assisted laparoscopic prostatectomy: a prospective randomized controlled study.
    BMC urology, 2021, Feb-26, Volume: 21, Issue:1

    Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Humans; Injections, Spinal; La

2021
Impact of thoracic epidural analgesia on blood loss in radical retropubic prostatectomy.
    Urologia internationalis, 2014, Volume: 93, Issue:2

    Topics: Administration, Intravenous; Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, General; Ane

2014
Selective Low-Dose Spinal Anesthesia for Transrectal Prostate Biopsy: A Prospective and Randomized Study.
    Journal of endourology, 2015, Volume: 29, Issue:12

    Topics: Aged; Anesthesia, Local; Anesthesia, Spinal; Anesthetics, Local; Biopsy, Large-Core Needle; Bupivaca

2015
The duration of intrathecal bupivacaine mixed with lidocaine.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:3

    Topics: Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Synergism; Female; Humans; Injectio

2008
The duration of intrathecal bupivacaine mixed with lidocaine.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:3

    Topics: Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Synergism; Female; Humans; Injectio

2008
The duration of intrathecal bupivacaine mixed with lidocaine.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:3

    Topics: Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Synergism; Female; Humans; Injectio

2008
The duration of intrathecal bupivacaine mixed with lidocaine.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:3

    Topics: Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Synergism; Female; Humans; Injectio

2008
Spinal anesthesia for transurethral resection operations: bupivacaine versus levobupivacaine.
    Minerva anestesiologica, 2008, Volume: 74, Issue:12

    Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Double-Blind Method; Humans; Levobupivaca

2008
Epidural and general anesthesia versus general anesthesia in radical prostatectomy.
    Medicina (Kaunas, Lithuania), 2009, Volume: 45, Issue:10

    Topics: Anesthesia, Epidural; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesth

2009
'Multimodal' approach to management of prostate biopsy pain and effects on sexual function: efficacy of levobupivacaine adjuvant to diclofenac sodium - a prospective randomized trial.
    Andrologia, 2010, Volume: 42, Issue:1

    Topics: Aged; Analgesia; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, Needle; Bupiva

2010
Spinal anesthesia for transurethral resection operations: levobupivacaine with or without fentanyl.
    Middle East journal of anaesthesiology, 2010, Volume: 20, Issue:4

    Topics: Aged; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Double-Blind Method;

2010
Wound infusion of bupivacaine following radical retropubic prostatectomy: a randomised placebo-controlled clinical study.
    European journal of anaesthesiology, 2013, Volume: 30, Issue:3

    Topics: Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Local; Bupivacaine; Catheters; Double-B

2013
Levobupivacaine versus racemic bupivacaine in spinal anaesthesia for urological surgery.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:6

    Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Blood Pressure; Bupivacaine; Double-Blind Method; Fema

2003
General versus spinal anesthesia in patients undergoing radical retropubic prostatectomy: results of a prospective, randomized study.
    Urology, 2004, Volume: 64, Issue:1

    Topics: Adenocarcinoma; Aged; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Spinal; Blood Los

2004
Prostate HDR radiation therapy: a comparative study evaluating the effectiveness of pain management with peripheral PCA vs. PCEA.
    Urologic nursing, 2006, Volume: 26, Issue:1

    Topics: Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Benchmar

2006

Other Studies

10 other studies available for bupivacaine and Prostatic Neoplasms

ArticleYear
Redox mechanism of levobupivacaine cytostatic effect on human prostate cancer cells.
    Redox biology, 2018, Volume: 18

    Topics: Adenosine Triphosphate; Anesthetics, Local; Antineoplastic Agents; Bupivacaine; Cell Cycle Checkpoin

2018
Wound infusion of bupivacaine following radical retropubic prostatectomy.
    European journal of anaesthesiology, 2014, Volume: 31, Issue:1

    Topics: Analgesia; Anesthetics, Local; Bupivacaine; Humans; Male; Prostatectomy; Prostatic Neoplasms

2014
Reply to: Wound infusion of bupivacaine following radical retropubic prostatectomy.
    European journal of anaesthesiology, 2014, Volume: 31, Issue:1

    Topics: Analgesia; Anesthetics, Local; Bupivacaine; Humans; Male; Prostatectomy; Prostatic Neoplasms

2014
Bilateral Continuous Quadratus Lumborum Block for Acute Postoperative Abdominal Pain as a Rescue After Opioid-Induced Respiratory Depression.
    A & A case reports, 2015, Oct-01, Volume: 5, Issue:7

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Bupivacaine; Humans; Male; Middle Aged; Nerve Blo

2015
Bilateral Continuous Quadratus Lumborum Block for Acute Postoperative Abdominal Pain as a Rescue After Opioid-Induced Respiratory Depression.
    A & A case reports, 2015, Oct-01, Volume: 5, Issue:7

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Bupivacaine; Humans; Male; Middle Aged; Nerve Blo

2015
Bilateral Continuous Quadratus Lumborum Block for Acute Postoperative Abdominal Pain as a Rescue After Opioid-Induced Respiratory Depression.
    A & A case reports, 2015, Oct-01, Volume: 5, Issue:7

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Bupivacaine; Humans; Male; Middle Aged; Nerve Blo

2015
Bilateral Continuous Quadratus Lumborum Block for Acute Postoperative Abdominal Pain as a Rescue After Opioid-Induced Respiratory Depression.
    A & A case reports, 2015, Oct-01, Volume: 5, Issue:7

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Bupivacaine; Humans; Male; Middle Aged; Nerve Blo

2015
Local anesthetic bupivacaine induced ovarian and prostate cancer apoptotic cell death and underlying mechanisms in vitro.
    Scientific reports, 2016, 05-19, Volume: 6

    Topics: Anesthetics, Local; Apoptosis; Bupivacaine; Caspases; Cell Line, Tumor; Cell Movement; Cell Prolifer

2016
Transrectal-HIFU as primary minimally-invasive option for localized prostate cancer. Is spinal anaesthesia cost-effective? A single centre experience in over 100 patients.
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2009, Volume: 81, Issue:1

    Topics: Adjuvants, Anesthesia; Aged; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cost-Benefit Analy

2009
Intrathecal infusion of bupivacaine and clonidine provides effective analgesia in a terminally ill child.
    Paediatric anaesthesia, 2012, Volume: 22, Issue:2

    Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Bupivacaine; Clonidine; Fatal Outcome; Humans; Infant

2012
[Modified technique for transurethral resection of the prostate with suprapubic drainage and local anesthesia].
    Actas urologicas espanolas, 2003, Volume: 27, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Cystost

2003
Successful resuscitation after cardiovascular collapse following accidental intravenous infusion of levobupivacaine during general anesthesia.
    Anesthesiology, 2005, Volume: 103, Issue:5

    Topics: Anesthesia, General; Anesthetics, Local; Brachytherapy; Bupivacaine; Cardiopulmonary Resuscitation;

2005
[Our experience of spinal anesthesia for transurethral resection of the bladder and prostate. Retrospective study of 334 patients operated in 1986].
    Journal d'urologie, 1990, Volume: 96, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Bupivacaine; Humans; Intraoperative Complication

1990