bupivacaine has been researched along with Phantom Limb in 18 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Phantom Limb: Perception of painful and nonpainful phantom sensations that occur following the complete or partial loss of a limb. The majority of individuals with an amputated extremity will experience the impression that the limb is still present, and in many cases, painful. (From Neurol Clin 1998 Nov;16(4):919-36; Brain 1998 Sep;121(Pt 9):1603-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report the efficacy of perioperative infusion of clonidine and bupivacaine for above-knee amputation in a patient with a history of phantom limb pain in the same extremity after a previous below-knee amputation." | 7.74 | The efficacy of postoperative perineural infusion of bupivacaine and clonidine after lower extremity amputation in preventing phantom limb and stump pain. ( Adesioye, J; Madabhushi, L; Reuben, SS; Steinberg, RB, 2007) |
| "Two cases are reported of patients with phantom limb pain after lower limb amputation and requiring surgery of their stump." | 5.29 | [Temporary relief from pain in the phantom limb after spinal anesthesia using a combination of bupivacaine and clonidine]. ( Bonnet, F; Gentili, ME, 1993) |
| "25% bupivacaine in myofascial hyperalgesic areas attenuated phantom limb pain and affected phantom limb sensation." | 5.14 | Phantom limb pain relief by contralateral myofascial injection with local anaesthetic in a placebo-controlled study: preliminary results. ( Biella, GE; Casale, R; Ceccherelli, F; Labeeb, AA, 2009) |
| "We report the efficacy of perioperative infusion of clonidine and bupivacaine for above-knee amputation in a patient with a history of phantom limb pain in the same extremity after a previous below-knee amputation." | 3.74 | The efficacy of postoperative perineural infusion of bupivacaine and clonidine after lower extremity amputation in preventing phantom limb and stump pain. ( Adesioye, J; Madabhushi, L; Reuben, SS; Steinberg, RB, 2007) |
| "Phantom limb pain was graded using a four-grade scale." | 2.84 | The Preventive Value of Epidural Calcitonin in Patients with Lower Limb Amputation. ( Aborahma, AM; Yousef, AA, 2017) |
| "Study endpoints were rate of stump and phantom pain, intensity of stump and phantom pain, and consumption of opioids." | 2.68 | Randomised trial of epidural bupivacaine and morphine in prevention of stump and phantom pain in lower-limb amputation. ( Christensen, JH; Ilkjaer, S; Jensen, TS; Krøner, K; Nikolajsen, L, 1997) |
| "Bupivacaine 0." | 2.67 | Continuous regional analgesia by intraneural block: effect on postoperative opioid requirements and phantom limb pain following amputation. ( Edwards, WT; Elizaga, AM; Hansen, ST; Sharar, SR; Smith, DG, 1994) |
| "Clonidine has been shown to be an effective postoperative analgesia when applied epidurally." | 2.67 | Prevention of phantom pain after major lower limb amputation by epidural infusion of diamorphine, clonidine and bupivacaine. ( Bradley, JW; Dark, CH; Jahangiri, M; Jayatunga, AP, 1994) |
| "During the blockade, both phantom pain and the referred cramp were abolished, while a referred sensation of "being touched at the phantom" persisted." | 1.48 | Referred cramping phantom hand pain elicited in the face and eliminated by peripheral nerve block. ( Dietrich, C; Hofmann, GO; Miltner, WHR; Nehrdich, S; Ritter, A; Weiss, T; Zimmer, A, 2018) |
| "Two cases are reported of patients with phantom limb pain after lower limb amputation and requiring surgery of their stump." | 1.29 | [Temporary relief from pain in the phantom limb after spinal anesthesia using a combination of bupivacaine and clonidine]. ( Bonnet, F; Gentili, ME, 1993) |
| "The triggering of phantom limb pain by subarachnoid or epidural anaesthesia has been well described leading to the suggestion that neuraxial regional anaesthesia is relatively contraindicated in lower limb amputees." | 1.29 | Regional anaesthesia for repeat Caesarean section in a patient with phantom limb pain. ( Carrie, LE; Glynn, CJ; Uncles, DR, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (61.11) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McCormick, ZL | 1 |
| Hendrix, A | 1 |
| Dayanim, D | 1 |
| Clay, B | 1 |
| Kirsling, A | 1 |
| Harden, N | 1 |
| Dietrich, C | 1 |
| Nehrdich, S | 1 |
| Zimmer, A | 1 |
| Ritter, A | 1 |
| Hofmann, GO | 1 |
| Miltner, WHR | 1 |
| Weiss, T | 1 |
| Yousef, AA | 1 |
| Aborahma, AM | 1 |
| Casale, R | 1 |
| Ceccherelli, F | 1 |
| Labeeb, AA | 1 |
| Biella, GE | 1 |
| Madabhushi, L | 1 |
| Reuben, SS | 1 |
| Steinberg, RB | 1 |
| Adesioye, J | 1 |
| Ivani, G | 1 |
| Mossetti, V | 1 |
| Andreacchio, A | 1 |
| Lee, E | 1 |
| Donovan, K | 1 |
| Elizaga, AM | 1 |
| Smith, DG | 1 |
| Sharar, SR | 1 |
| Edwards, WT | 1 |
| Hansen, ST | 1 |
| Jahangiri, M | 1 |
| Jayatunga, AP | 1 |
| Bradley, JW | 1 |
| Dark, CH | 1 |
| Gentili, ME | 1 |
| Bonnet, F | 1 |
| Uncles, DR | 1 |
| Glynn, CJ | 1 |
| Carrie, LE | 1 |
| Pavy, TJ | 1 |
| Doyle, DL | 1 |
| Nikolajsen, L | 2 |
| Ilkjaer, S | 2 |
| Christensen, JH | 1 |
| Krøner, K | 1 |
| Jensen, TS | 2 |
| Enneking, FK | 1 |
| Morey, TE | 1 |
| McQuay, HJ | 1 |
| Moore, RA | 1 |
| Kalso, E | 1 |
| Isaacson, SA | 1 |
| Funderburk, M | 1 |
| Yang, J | 1 |
| Coombs, DW | 1 |
| Fine, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Infrared (FLIR) Imaging as a Monitor for Sympathetic Blocks in Complex Regional Pain Syndrome (CRPS)[NCT05693337] | 30 participants (Actual) | Observational | 2023-01-09 | Completed | |||
| A Prospective, Randomized Trial of Liposomal Bupivacaine Compared to Continuous Nerve Catheters on Pain Control and Post-Operative Opioid Use in Receiving Popliteal Nerve Blocks for Below the Knee Amputation[NCT05140499] | Phase 4 | 30 participants (Anticipated) | Interventional | 2022-08-15 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 trials available for bupivacaine and Phantom Limb
| Article | Year |
|---|---|
The Preventive Value of Epidural Calcitonin in Patients with Lower Limb Amputation.
Topics: Adult; Aged; Amputation, Surgical; Analgesics; Bupivacaine; Calcitonin; Double-Blind Method; Female; | 2017 |
Phantom limb pain relief by contralateral myofascial injection with local anaesthetic in a placebo-controlled study: preliminary results.
Topics: Aged; Aged, 80 and over; Amputation, Surgical; Amputation, Traumatic; Anesthetics, Local; Bupivacain | 2009 |
Continuous regional analgesia by intraneural block: effect on postoperative opioid requirements and phantom limb pain following amputation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amputation, Surgical; Anesthesia, Conduction; Bupivacain | 1994 |
Prevention of phantom pain after major lower limb amputation by epidural infusion of diamorphine, clonidine and bupivacaine.
Topics: Adult; Aged; Aged, 80 and over; Amputation, Surgical; Analgesics; Bupivacaine; Clonidine; Drug Combi | 1994 |
Randomised trial of epidural bupivacaine and morphine in prevention of stump and phantom pain in lower-limb amputation.
Topics: Analgesia, Epidural; Bupivacaine; Double-Blind Method; Female; Humans; Intraoperative Period; Male; | 1997 |
Effect of preoperative extradural bupivacaine and morphine on stump sensation in lower limb amputees.
Topics: Adult; Aged; Amputation Stumps; Amputation, Surgical; Analgesia, Epidural; Analgesics, Opioid; Anest | 1998 |
Regulation of proprioceptive memory by subarachnoid regional anesthesia.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Conduction; Anesthetics, Local; Bupivacaine; Female; Hum | 2000 |
11 other studies available for bupivacaine and Phantom Limb
| Article | Year |
|---|---|
Lumbar Sympathetic Plexus Block as a Treatment for Postamputation Pain: Methodology for a Randomized Controlled Trial.
Topics: Amputation, Surgical; Autonomic Nerve Block; Bupivacaine; Female; Humans; Low Back Pain; Male; Pain | 2018 |
Referred cramping phantom hand pain elicited in the face and eliminated by peripheral nerve block.
Topics: Amputees; Anesthetics, Local; Brachial Plexus; Bupivacaine; Face; Female; Hand; Humans; Magnetic Res | 2018 |
The efficacy of postoperative perineural infusion of bupivacaine and clonidine after lower extremity amputation in preventing phantom limb and stump pain.
Topics: Adjuvants, Anesthesia; Aged, 80 and over; Amputation Stumps; Analgesia, Epidural; Analgesics; Bupiva | 2007 |
Ultrasound-guided peripheral catheter placement for upper limb amputation in a 12-year-old boy: possible phantom limb pain prevention?
Topics: Amputation, Surgical; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Bone Ne | 2008 |
Reactivation of phantom limb pain after combined interscalene brachial plexus block and general anesthesia: successful treatment with intravenous lidocaine.
Topics: Anesthesia, General; Brachial Plexus; Bupivacaine; Female; Humans; Injections, Intravenous; Isoflura | 1995 |
[Temporary relief from pain in the phantom limb after spinal anesthesia using a combination of bupivacaine and clonidine].
Topics: Aged; Amputation, Surgical; Anesthesia, Spinal; Bupivacaine; Clonidine; Drug Therapy, Combination; H | 1993 |
Regional anaesthesia for repeat Caesarean section in a patient with phantom limb pain.
Topics: Adult; Analgesics, Opioid; Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, Obstetrical; An | 1996 |
Prevention of phantom limb pain by infusion of local anaesthetic into the sciatic nerve.
Topics: Aged; Amputation, Surgical; Analgesia; Anesthetics, Local; Bupivacaine; Fatal Outcome; Humans; Injec | 1996 |
Continuous postoperative infusion of a regional anesthetic after an amputation of the lower extremity. A randomized clinical trial.
Topics: Amputation, Surgical; Anesthetics, Local; Bupivacaine; Humans; Injections; Leg; Myelin Sheath; Nerve | 1997 |
Phantom-limb pain.
Topics: Amputation, Surgical; Analgesia, Epidural; Bupivacaine; Humans; Leg; Pain; Pain, Postoperative; Phan | 1998 |
Spinal anesthesia using subcutaneously implanted pumps for intrathecal drug infusion.
Topics: Adult; Anesthesia, Spinal; Bupivacaine; Equipment Design; Equipment Failure; Humans; Infusion Pumps, | 1991 |