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bupivacaine and Peripheral Nerve Injury

bupivacaine has been researched along with Peripheral Nerve Injury in 12 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Research Excerpts

ExcerptRelevanceReference
" One minute after performing a second stellate ganglion block the patient showed signs of apnea and paralysis of the upper extremities and face, with no involvement of oculomotor muscles or the lower extremities, and no loss of consciousness."3.70[A possibility of central diffusion during stellate ganglion blockade: "the sheath of the spinal rachidian nerve"]. ( Escudero, A; Fas, MJ; Ortiz, M; Roca, G; Soriano, C; Vidal, F, 1999)
"Bupivacaine microspheres treatment produced conduction blockade with a complete lack of sensory responsiveness in the sural territory for 6 to 10 days."1.32Development of neuropathic pain in the rat spared nerve injury model is not prevented by a peripheral nerve block. ( Berde, CB; Decosterd, I; Gilliard, N; Papaloïzos, M; Spahn, DR; Suter, MR; Woolf, CJ, 2003)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's2 (16.67)18.2507
2000's3 (25.00)29.6817
2010's4 (33.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Wu, CC1
Chang, CY1
Tzeng, CY1
Huang, JH1
Hung, CJ1
Chen, WY1
Liao, SL1
Kuan, YH1
Chen, CJ1
Byram, SC2
Bialek, SE1
Husak, VA1
Balcarcel, D1
Park, J1
Dang, J1
Foecking, EM1
Ji, ZH1
Liu, ZJ1
Liu, ZT1
Zhao, W1
Williams, BA2
Zhang, HF1
Li, L1
Xu, SY1
Farber, SJ1
Saheb-Al-Zamani, M1
Zieske, L1
Laurido-Soto, O1
Bery, A1
Hunter, D2
Johnson, P1
Mackinnon, SE1
Ibinson, JW1
Gould, AJ1
Mangione, MP1
Byram, SW1
Miller, NM1
Fargo, KN1
Xie, W1
Strong, JA1
Zhang, JM1
de Santiago, J1
Santos, LJ1
Giron, J1
Suter, MR1
Papaloïzos, M1
Berde, CB1
Woolf, CJ1
Gilliard, N1
Spahn, DR1
Decosterd, I1
Gentili, F1
Hudson, AR1
Kline, DG1
Colburn, RW1
DeLeo, JA1
Rickman, AJ1
Yeager, MP1
Kwon, P1
Hickey, WF1
Soriano, C1
Ortiz, M1
Fas, MJ1
Escudero, A1
Roca, G1
Vidal, F1

Other Studies

12 other studies available for bupivacaine and Peripheral Nerve Injury

ArticleYear
Preventive Intrathecal Injection of Bupivacaine Alleviated Microglia Activation and Neuropathic Pain in a Rat Model of Chronic Constriction Injury.
    International journal of molecular sciences, 2022, Jun-28, Volume: 23, Issue:13

    Topics: Animals; Bupivacaine; Constriction; Crush Injuries; Cytokines; HMGB1 Protein; Hyperalgesia; Injectio

2022
Distinct neurotoxic effects of select local anesthetics on facial nerve injury and recovery.
    Restorative neurology and neuroscience, 2020, Volume: 38, Issue:2

    Topics: Anesthetics, Local; Animals; Bupivacaine; Cell Death; Cell Survival; Facial Nerve; Facial Nerve Inju

2020
Diphenyleneiodonium Mitigates Bupivacaine-Induced Sciatic Nerve Damage in a Diabetic Neuropathy Rat Model by Attenuating Oxidative Stress.
    Anesthesia and analgesia, 2017, Volume: 125, Issue:2

    Topics: Anesthetics, Local; Animals; Bupivacaine; Diabetic Neuropathies; Electrophysiology; Enzyme Inhibitor

2017
Peripheral nerve injury after local anesthetic injection.
    Anesthesia and analgesia, 2013, Volume: 117, Issue:3

    Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Injections; Lidocaine; Male; Microscopy, Electron;

2013
The Incidence of Peripheral Nerve Injury After Multimodal Perineural Anesthesia/Analgesia Does Not Appear to Differ from That Following Single-Drug Nerve Blocks (2011-2014).
    Pain medicine (Malden, Mass.), 2017, 04-01, Volume: 18, Issue:4

    Topics: Amides; Analgesics; Anesthetics, Local; Bupivacaine; Buprenorphine; Dexamethasone; Drug Therapy, Com

2017
Bupivacaine increases the rate of motoneuron death following peripheral nerve injury.
    Restorative neurology and neuroscience, 2017, Volume: 35, Issue:1

    Topics: Animals; Axotomy; Bupivacaine; Cell Death; Disease Models, Animal; Lidocaine; Male; Mice; Mice, Inbr

2017
Early blockade of injured primary sensory afferents reduces glial cell activation in two rat neuropathic pain models.
    Neuroscience, 2009, Jun-02, Volume: 160, Issue:4

    Topics: Animals; Biomarkers; Bupivacaine; CD11b Antigen; Disease Models, Animal; Ganglia, Spinal; Glial Fibr

2009
Low-dose, low-concentration spinal anesthesia may help to detect surgery-related nerve injury.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:9

    Topics: Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Female; Humans; Levobupivacaine; Middle Aged; P

2009
Development of neuropathic pain in the rat spared nerve injury model is not prevented by a peripheral nerve block.
    Anesthesiology, 2003, Volume: 99, Issue:6

    Topics: Animals; Bupivacaine; Hyperalgesia; Male; Nerve Block; Pain Management; Peripheral Nerve Injuries; R

2003
Nerve injection injury with local anesthetic agents: a light and electron microscopic, fluorescent microscopic, and horseradish peroxidase study.
    Neurosurgery, 1980, Volume: 6, Issue:3

    Topics: Anesthetics, Local; Animals; Bupivacaine; Evans Blue; Injections; Lidocaine; Mepivacaine; Microscopy

1980
Dissociation of microglial activation and neuropathic pain behaviors following peripheral nerve injury in the rat.
    Journal of neuroimmunology, 1997, Volume: 79, Issue:2

    Topics: Anesthetics, Local; Animals; Astrocytes; Behavior, Animal; Bupivacaine; Freezing; Immunohistochemist

1997
[A possibility of central diffusion during stellate ganglion blockade: "the sheath of the spinal rachidian nerve"].
    Revista espanola de anestesiologia y reanimacion, 1999, Volume: 46, Issue:3

    Topics: Adult; Anesthetics, Local; Apnea; Autonomic Nerve Block; Bupivacaine; Diffusion; Facial Paralysis; F

1999