bupivacaine has been researched along with Pancreatic Neoplasms in 23 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-three patients underwent 36 direct celiac ganglia injections for unresectable pancreatic cancer (CGN N = 17, CGB N = 1) or chronic pancreatitis (CGN N = 5, CGB N = 13) with bupivacaine (0." | 3.74 | Initial evaluation of the efficacy and safety of endoscopic ultrasound-guided direct Ganglia neurolysis and block. ( Chari, ST; Clain, JE; de la Mora, JG; Gleeson, FC; Levy, MJ; Pearson, RK; Pelaez, MC; Petersen, BT; Rajan, E; Topazian, MD; Vege, SS; Wang, KK; Wiersema, MJ, 2008) |
| "This study involved patients with pancreatic cancer-related pain." | 2.76 | A prospective, randomized study of EUS-guided celiac plexus neurolysis for pancreatic cancer: one injection or two? ( Al-Haddad, M; DeWitt, J; Howard, TJ; Johnson, C; Juan, M; LeBlanc, JK; Lillemoe, KD; McGreevy, K; McHenry, L; Sherman, S, 2011) |
| "Pancreatic cancer is an aggressive tumor associated with high mortality." | 2.71 | Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer: a randomized controlled trial. ( Carns, PE; Kinney, MO; Mantilla, CB; Martin, DP; Schroeder, DR; Warner, DO; Wilson, JL; Wong, GY, 2004) |
| "Here, pancreatic cancer and treatment associated pain are reviewed along with current treatment strategies." | 2.66 | Pathogenesis and Treatment of Pancreatic Cancer Related Pain. ( Brothers, SP; Lohse, I, 2020) |
| "Chronic abdominal pain is a devastating problem for patients and providers, due to the difficulty of effectively treating the entity." | 2.50 | Celiac plexus block in the management of chronic abdominal pain. ( Candido, KD; Knezevic, NN; Raja, O; Rana, MV, 2014) |
| "Pancreatic cancer is a common gastrointestinal malignancy with a poor prognosis." | 2.43 | Endoscopic ultrasound-guided celiac plexus neurolysis for pancreatic cancer pain: a single-institution experience and review of the literature. ( Meyers, FJ; Tran, QN; Urayama, S, 2006) |
| " These patients had a significant reduction in the frequency and dosage of analgesics." | 1.42 | [THE FIRST CLINICAL EXPERIENCE IN THE CELIAC PLEXUS BLOCKADE UNDER ENDOSCOPIC ULTRASOUND NAVIGATION IN PATIENTS WITH PANCREATIC CANCER]. ( Abuzarova, GR; Karpova, ES; Pavlov, PV; Pirogov, SS; Sarmanaeva, RR; Sokolov, VV, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.04) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 7 (30.43) | 29.6817 |
| 2010's | 8 (34.78) | 24.3611 |
| 2020's | 3 (13.04) | 2.80 |
| Authors | Studies |
|---|---|
| Lohse, I | 1 |
| Brothers, SP | 1 |
| Saleh, AAG | 1 |
| Sultan, A | 1 |
| Hammouda, MA | 1 |
| Shawki, A | 1 |
| El Ghaffar, MA | 1 |
| Zhao, Y | 1 |
| Guo, X | 1 |
| Wang, K | 1 |
| Chen, Q | 1 |
| Wang, Y | 1 |
| Chen, L | 1 |
| Gao, W | 1 |
| Cheng, B | 1 |
| Jin, Z | 1 |
| Freitag, FA | 1 |
| Bozak, VL | 1 |
| do Carmo, MP | 1 |
| Froes, TR | 1 |
| Duque, JC | 1 |
| Doi, S | 1 |
| Yasuda, I | 1 |
| Kawakami, H | 1 |
| Hayashi, T | 1 |
| Hisai, H | 1 |
| Irisawa, A | 1 |
| Mukai, T | 1 |
| Katanuma, A | 1 |
| Kubota, K | 1 |
| Ohnishi, T | 1 |
| Ryozawa, S | 1 |
| Hara, K | 1 |
| Itoi, T | 1 |
| Hanada, K | 1 |
| Yamao, K | 1 |
| Bhatnagar, S | 1 |
| Joshi, S | 1 |
| Rana, SP | 1 |
| Mishra, S | 1 |
| Garg, R | 1 |
| Ahmed, SM | 1 |
| Gao, L | 1 |
| Yang, YJ | 1 |
| Xu, HY | 1 |
| Zhou, J | 1 |
| Hong, H | 1 |
| Wang, YL | 1 |
| Li, DC | 1 |
| Rana, MV | 1 |
| Candido, KD | 1 |
| Raja, O | 1 |
| Knezevic, NN | 1 |
| Pavlov, PV | 1 |
| Sokolov, VV | 1 |
| Pirogov, SS | 1 |
| Karpova, ES | 1 |
| Abuzarova, GR | 1 |
| Sarmanaeva, RR | 1 |
| Polati, E | 1 |
| Luzzani, A | 1 |
| Schweiger, V | 1 |
| Finco, G | 1 |
| Ischia, S | 1 |
| LeBlanc, JK | 1 |
| Al-Haddad, M | 1 |
| McHenry, L | 1 |
| Sherman, S | 1 |
| Juan, M | 1 |
| McGreevy, K | 1 |
| Johnson, C | 1 |
| Howard, TJ | 1 |
| Lillemoe, KD | 1 |
| DeWitt, J | 1 |
| Levy, MJ | 2 |
| Chari, ST | 2 |
| Wiersema, MJ | 3 |
| Hoffman, BJ | 1 |
| Wong, GY | 1 |
| Schroeder, DR | 1 |
| Carns, PE | 1 |
| Wilson, JL | 1 |
| Martin, DP | 1 |
| Kinney, MO | 1 |
| Mantilla, CB | 1 |
| Warner, DO | 1 |
| Tran, QN | 1 |
| Urayama, S | 1 |
| Meyers, FJ | 1 |
| Topazian, MD | 1 |
| Clain, JE | 1 |
| Rajan, E | 1 |
| Wang, KK | 1 |
| de la Mora, JG | 1 |
| Gleeson, FC | 1 |
| Pearson, RK | 1 |
| Pelaez, MC | 1 |
| Petersen, BT | 1 |
| Vege, SS | 1 |
| Wiersema, LM | 1 |
| Johnston, MK | 1 |
| Harland, SP | 1 |
| Rykowski, JJ | 1 |
| Hilgier, M | 1 |
| Hol, PK | 1 |
| Kvarstein, G | 1 |
| Viken, O | 1 |
| Smedby, O | 1 |
| Tønnessen, TI | 1 |
| Duraj, M | 1 |
| Kurzbauer, R | 1 |
| Squier, R | 1 |
| Morrow, JS | 1 |
| Roman, R | 1 |
| Durrani, Z | 1 |
| Winnie, AP | 1 |
| Ikuta, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Controlled Trial of Endoscopic Ultrasound Guided Celiac Plexus Blockade (EUS-CPB) With Standard Plexus Injection vs. Direct Celiac Ganglia Block for Treatment of Pain in Chronic Pancreatitis.[NCT03070210] | 29 participants (Actual) | Interventional | 2017-01-25 | Completed | |||
| A Randomized Controlled Trial on Endoscopic Ultrasound-guided Celiac Ganglion Neurolysis Versus Percutaneous Celiac Plexus Neurolysis in Patients With Inoperable Cancer[NCT02356640] | Phase 2/Phase 3 | 3 participants (Actual) | Interventional | 2014-08-31 | Terminated (stopped due to Poor recruitment) | ||
| Efficacy and Safety of Paragastric Neural Block in Controlling Pain, Nausea and Vomiting After Laparoscopic Sleeve Gastrectomy; Prospective Randomized Controlled Double-blind Study[NCT05984160] | 90 participants (Actual) | Interventional | 2023-05-09 | Active, not recruiting | |||
| A Prospective Study of Celiac Block Technique: One Injection or Two?[NCT00583479] | Phase 4 | 100 participants (Anticipated) | Interventional | 2002-06-30 | Completed | ||
| A Randomize Double-Blind Control Trial Study Comparing Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis W/Wo Bupivacaine In Patient Being Treated Palliatively For Pancreatic Cancer[NCT02682082] | 22 participants (Actual) | Interventional | 2016-05-27 | Terminated (stopped due to Closed by CHUM REB for incomplete documentation of research activities.) | |||
| Percutaneous Cryoablation for the Palliation of Abdominal Pain Associated With Pancreatic Cancer[NCT01335945] | Phase 1 | 14 participants (Actual) | Interventional | 2011-08-31 | Terminated (stopped due to Low enrollment & subjects didn't survive to study end due to cancer progression.) | ||
| Celiac Plexus Radiosurgery for Pain Management in Advanced Cancer Patients - a Phase II Trial[NCT02356406] | Phase 2 | 52 participants (Anticipated) | Interventional | 2014-01-31 | Recruiting | ||
| Endovascular Denervation in Patients With Cancer Pain[NCT03431922] | 20 participants (Anticipated) | Interventional | 2017-09-21 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for bupivacaine and Pancreatic Neoplasms
| Article | Year |
|---|---|
Pathogenesis and Treatment of Pancreatic Cancer Related Pain.
Topics: Abdominal Pain; Analgesics, Opioid; Bupivacaine; Cancer Pain; Cisplatin; Humans; Mucositis; Pain Man | 2020 |
Celiac plexus block in the management of chronic abdominal pain.
Topics: Abdominal Pain; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Chronic Disea | 2014 |
Endoscopic ultrasound-guided celiac neurolysis.
Topics: Abdominal Pain; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Endosonography; Ganglia, Sympathe | 2012 |
EUS-guided celiac plexus block/neurolysis.
Topics: Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Celiac Plexus; Endosonography; Humans; Ne | 2002 |
Endoscopic ultrasound-guided celiac plexus neurolysis for pancreatic cancer pain: a single-institution experience and review of the literature.
Topics: Abdominal Pain; Adenocarcinoma; Adult; Anesthetics, Local; Autonomic Nerve Block; Biopsy, Fine-Needl | 2006 |
6 trials available for bupivacaine and Pancreatic Neoplasms
| Article | Year |
|---|---|
Endoscopic ultrasound-guided celiac ganglia neurolysis vs. celiac plexus neurolysis: a randomized multicenter trial.
Topics: Abdominal Pain; Aged; Aged, 80 and over; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Cel | 2013 |
Endoscopic ultrasound-guided celiac ganglia neurolysis vs. celiac plexus neurolysis: a randomized multicenter trial.
Topics: Abdominal Pain; Aged; Aged, 80 and over; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Cel | 2013 |
Endoscopic ultrasound-guided celiac ganglia neurolysis vs. celiac plexus neurolysis: a randomized multicenter trial.
Topics: Abdominal Pain; Aged; Aged, 80 and over; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Cel | 2013 |
Endoscopic ultrasound-guided celiac ganglia neurolysis vs. celiac plexus neurolysis: a randomized multicenter trial.
Topics: Abdominal Pain; Aged; Aged, 80 and over; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Cel | 2013 |
Bedside ultrasound-guided celiac plexus neurolysis in upper abdominal cancer patients: a randomized, prospective study for comparison of percutaneous bilateral paramedian vs. unilateral paramedian needle-insertion technique.
Topics: Abdominal Pain; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Female; Gallb | 2014 |
A randomized clinical trial of nerve block to manage end-stage pancreatic cancerous pain.
Topics: Aged; Anesthetics, Local; Bupivacaine; Celiac Plexus; Female; Humans; Male; Middle Aged; Nerve Block | 2014 |
A prospective, randomized study of EUS-guided celiac plexus neurolysis for pancreatic cancer: one injection or two?
Topics: Abdominal Pain; Anesthetics, Local; Bupivacaine; Celiac Plexus; Dose-Response Relationship, Drug; En | 2011 |
Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer: a randomized controlled trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Bupivacaine; Celiac Plexus; Doub | 2004 |
Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer: a randomized controlled trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Bupivacaine; Celiac Plexus; Doub | 2004 |
Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer: a randomized controlled trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Bupivacaine; Celiac Plexus; Doub | 2004 |
Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer: a randomized controlled trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Bupivacaine; Celiac Plexus; Doub | 2004 |
Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer: a randomized controlled trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Bupivacaine; Celiac Plexus; Doub | 2004 |
Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer: a randomized controlled trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Bupivacaine; Celiac Plexus; Doub | 2004 |
Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer: a randomized controlled trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Bupivacaine; Celiac Plexus; Doub | 2004 |
Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer: a randomized controlled trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Bupivacaine; Celiac Plexus; Doub | 2004 |
Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer: a randomized controlled trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Bupivacaine; Celiac Plexus; Doub | 2004 |
Efficacy of neurolytic celiac plexus block in varying locations of pancreatic cancer: influence on pain relief.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Celiac Plexus; Female; Humans; Male | 2000 |
12 other studies available for bupivacaine and Pancreatic Neoplasms
| Article | Year |
|---|---|
Value of Adding Dexmedetomidine in Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis for Treatment of Pancreatic Cancer-Associated Pain.
Topics: Aged; Bupivacaine; Cancer Pain; Case-Control Studies; Celiac Plexus; Dexmedetomidine; Endosonography | 2021 |
A retrospective multicenter study comparing bupivacaine and ropivacaine in endoscopic ultrasound guided celiac plexus neurolysis.
Topics: Bupivacaine; Celiac Plexus; Humans; Pancreatic Neoplasms; Retrospective Studies; Ropivacaine; Ultras | 2021 |
Continuous transversus abdominis plane block for analgesia in three dogs with abdominal pain.
Topics: Abdominal Muscles; Abdominal Pain; Anesthetics, Local; Animals; Bupivacaine; Dog Diseases; Dogs; Mal | 2018 |
[THE FIRST CLINICAL EXPERIENCE IN THE CELIAC PLEXUS BLOCKADE UNDER ENDOSCOPIC ULTRASOUND NAVIGATION IN PATIENTS WITH PANCREATIC CANCER].
Topics: Aged; Aged, 80 and over; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Endosonography; Ethanol; | 2015 |
The role of neurolytic celiac plexus block in the treatment of pancreatic cancer pain.
Topics: Anesthetics, Local; Atropine; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Humans; Pain, Intra | 2008 |
Initial evaluation of the efficacy and safety of endoscopic ultrasound-guided direct Ganglia neurolysis and block.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Ag | 2008 |
Endosonography-guided celiac plexus neurolysis.
Topics: Abdominal Neoplasms; Aged; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; En | 1996 |
Spinal cord compression from precipitation of drug solute around an epidural catheter.
Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Catheters, Indwelling; Dec | 1998 |
MRI-guided celiac plexus block.
Topics: Abdominal Pain; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Chronic Disease; Female; Humans; | 2000 |
[Anesthesia of the celiac plexus in analgesia in cases of inoperable epigastric tumors].
Topics: Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Humans; Pain, Intractable; Palliative Care; Pancr | 1985 |
Pain therapy for pancreatic carcinoma with neurolytic celiac plexus block.
Topics: Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Humans; Pain, Intractable; Palliative Care; Pancr | 1989 |
Interpleural catheter analgesia for pancreatic pain.
Topics: Analgesia; Bupivacaine; Catheterization; Humans; Male; Middle Aged; Pain; Pancreatic Neoplasms; Pleu | 1988 |