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bupivacaine and Pain, Intractable

bupivacaine has been researched along with Pain, Intractable in 86 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Pain, Intractable: Persistent pain that is refractory to some or all forms of treatment.

Research Excerpts

ExcerptRelevanceReference
"Four patients with postherpetic neuralgia had their pain alleviated by epidural administration of ketamine."7.71[Usefulness of epidural administration of ketamine for relief of postherpetic neuralgia]. ( Ikeda, M; Machida, K; Mikawa, Y; Mizuno, J; Sugimoto, S, 2001)
" We present the case of the youngest reported child to have received intrathecal analgesia for terminal care: a 3-year-old boy with advanced pelvic rhabdomyosarcoma, whose refractory pain was managed effectively with an intrathecal infusion of bupivacaine and preservative-free clonidine."3.78Intrathecal infusion of bupivacaine and clonidine provides effective analgesia in a terminally ill child. ( Lauder, G; Whyte, E, 2012)
" Despite leptomeningeal infection during prolonged treatment, epidural analgesia at the lumbar level provided analgesia using very large doses of local anesthetics combined with clonidine and morphine."3.72Epidural analgesia at end of life: facing empirical contraindications. ( Eikermann, M; Exner, HJ; Peters, J, 2003)
"Four patients with postherpetic neuralgia had their pain alleviated by epidural administration of ketamine."3.71[Usefulness of epidural administration of ketamine for relief of postherpetic neuralgia]. ( Ikeda, M; Machida, K; Mikawa, Y; Mizuno, J; Sugimoto, S, 2001)
" One minute after performing a second stellate ganglion block the patient showed signs of apnea and paralysis of the upper extremities and face, with no involvement of oculomotor muscles or the lower extremities, and no loss of consciousness."3.70[A possibility of central diffusion during stellate ganglion blockade: "the sheath of the spinal rachidian nerve"]. ( Escudero, A; Fas, MJ; Ortiz, M; Roca, G; Soriano, C; Vidal, F, 1999)
"Up to 90% of patients with advanced cancer experience intractable pain."2.50Treatment of medically refractory cancer pain with a combination of intrathecal neuromodulation and neurosurgical ablation: case series and literature review. ( Bentley, JN; Patil, PG; Rosenberg, WS; Viswanathan, A, 2014)
" This study looks to establish a safe and efficacious fixed bupivacaine dosing algorithm in intrathecal pumps for cancer patients."1.56Evaluation of Fixed Intrathecal Bupivacaine Infusion Doses in the Oncologic Population. ( Baig, E; Chen, GH; Clement, K; Gulati, A; Laufer, I; Magram, YC; Spiegel, MA, 2020)
"A multidisciplinary interventional cancer pain service was established in the West of Scotland in 2008 with the aim of providing a safe and effective intrathecal drug delivery service for patients with difficult-to-control cancer pain."1.42Audit of intrathecal drug delivery for patients with difficult-to-control cancer pain shows a sustained reduction in pain severity scores over a 6-month period. ( McGhie, J; McGinn, G; Mitchell, A; Owen, M, 2015)
"Reducing and preventing postoperative pain are currently a topic of great interest."1.36Chronic, painful lower extremity wounds: postoperative pain management through the use of continuous infusion of regional anaesthesia supplied by a portable pump device. ( Armstrong, DG; Bharara, M; Fisher, TK; Scimeca, CL, 2010)
"A 48-year-old woman, diagnosed as colon cancer with metastases in the liver, lung, bone and left rectus abdominis, developed refractory left abdominal pain in spite of escalating administration of opioids and nerve block therapy, and intrathecal analgesia was applied."1.35[Intrathecal segmental analgesia with a single dose of bupivacaine for cancer pain in the abdominal wall]. ( Chigusa, S; Ikegaki, J; Kaetsu, H; Kato, H; Kurihara, Y, 2008)
" After the neurolytic block, the total dosage of morphine and diclofenac remained unchanged for 2 months."1.32Application of a mandibular nerve block using an indwelling catheter for intractable cancer pain. ( Kohase, H; Shibaji, T; Suzuki, N; Umino, M, 2004)
"In most cases, drug-related spinal cord injuries have resulted from the compression of a spinal inflammatory mass or abcess rather than from a direct neurotoxic effect."1.32Spinal cord lesion after long-term intrathecal clonidine and bupivacaine treatment for the management of intractable pain. ( Buchser, E; Chédel, D; Hirt, L; Maeder, P; Perren, F; Vingerhoets, F, 2004)
"We present two cases of cancer patients with intractable mechanical and visceral pain that was unrelieved with either comprehensive medical management or intrathecal morphine who received intrathecal bupivacaine."1.32Efficacy of intrathecal bupivacaine: how important is the flow rate? ( Buchser, E; Chédel, D; Durrer, A; Mustaki, JP, 2004)
"As the number of terminal cancer patients receiving continuous intrathecal infusion of opioids and local anesthetics for relief of pain increases, we decided to investigate the post-mortem findings of the spinal cord, meninges and nerve roots of patients after continuous intrathecal administration of morphine and combined with bupivacaine."1.30Neurohistopathological findings after continuous intrathecal administration of morphine or a morphine/bupivacaine mixture in cancer pain patients. ( de Lange, JJ; Spoelder, EM; van der Valk, P; Wagemans, MF; Zuurmond, WW, 1997)
" Bupivacaine-induced side effects were absent below a daily dosage of 30 mg by continuous infusion."1.29Long-term intrathecal infusion of morphine and morphine/bupivacaine mixtures in the treatment of cancer pain: a retrospective analysis of 51 cases. ( Crul, BJP; De Bock, M; Van Dongen, RTM, 1993)
"The treatment of severe cancer pain by intrathecal infusion of morphine and bupivacaine seems to be a promising method."1.29[Treatment of severe cancer pain via spinal catheters]. ( Andersen, JS; Markers, PI; Valentin, N, 1996)
" We conclude that epidural opioid-bupivacaine infusion is an effective and safe technique for long-term administration of analgesics in the refractory cancer patient."1.28Chronic epidural bupivacaine-opioid infusion in intractable cancer pain. ( Du Pen, SL; Hasche-Klunder, H; Kharasch, ED; Krembs, AW; Peterson, DG; Sloan, DC; Williams, A, 1992)
"Fifteen adult patients with cancer pain received 0."1.28[Epidural administration of bupivacaine in glycerine solution can prolong analgesia]. ( King, HK; Wooten, DJ; Xiao, CS, 1992)
"Headaches are among the most common pain syndromes encountered in clinical practice."1.28Cervical steroid epidural nerve blocks in the palliation of pain secondary to intractable tension-type headaches. ( Cronen, MC; Waldman, SD, 1990)
" The efficacy of the treatment was estimated from: 1) daily dosage (intraspinal and total opiates, and intraspinal bupivacaine), and 2) scores of non-opiate analgesic and sedative consumption, gait and daily activities, and amount and pattern of sleep."1.28Long-term intrathecal morphine and bupivacaine in "refractory" cancer pain. I. Results from the first series of 52 patients. ( Appelgren, L; Curelaru, I; Einarsson, S; Hultman, E; Linder, LE; Nitescu, P; Sjöberg, M, 1991)
" Incremental dosage and careful screening is recommended."1.28Coeliac plexus block and cephalic spread of injectate. ( Hardy, PA; Wells, JC, 1989)

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-199019 (22.09)18.7374
1990's28 (32.56)18.2507
2000's24 (27.91)29.6817
2010's13 (15.12)24.3611
2020's2 (2.33)2.80

Authors

AuthorsStudies
Chen, GH1
Spiegel, MA1
Magram, YC1
Baig, E1
Clement, K1
Laufer, I1
Gulati, A1
Michot, T1
Duysinx, P1
Belle, F1
Dresse, C1
Montupil, J1
Bonhomme, V1
Defresne, A1
Ju, Y1
Tian, D1
Tan, Y1
Fu, Z1
Perloff, MD1
Chung, JS1
Balga, I1
Gerber, H1
Schorno, XH1
Aebersold Keller, F1
Oehen, HP1
Yin, C1
Matchett, G1
Bentley, JN1
Viswanathan, A1
Rosenberg, WS1
Patil, PG1
Mitchell, A1
McGhie, J1
Owen, M1
McGinn, G1
Hayek, SM1
Sweet, JA1
Miller, JP1
Sayegh, RR1
Polati, E1
Luzzani, A1
Schweiger, V1
Finco, G1
Ischia, S1
Goodman, SR1
Smiley, RM1
Negron, MA1
Freedman, PA1
Landau, R1
Keskinbora, K1
Aydinli, I1
Sahai, AV1
Wyse, J1
Ahmed, M1
Acher, P1
Deane, AM1
Jefferies, ER1
Phull, JS1
Gallegos, CR1
Scimeca, CL1
Fisher, TK1
Bharara, M1
Armstrong, DG1
Sato, C1
Okabe, T1
Nakanishi, K1
Sakamoto, A1
Whyte, E1
Lauder, G1
Yuen, TS1
Ng, KF1
Tsui, SL1
Breitfeld, C1
Eikermann, M2
Kienbaum, P1
Peters, J2
Mercadante, S3
Villari, P3
Ferrera, P2
Arcuri, E2
Exner, HJ1
Kohase, H1
Umino, M1
Shibaji, T1
Suzuki, N1
Perren, F1
Buchser, E2
Chédel, D2
Hirt, L1
Maeder, P1
Vingerhoets, F1
Taha, J1
Favre, J1
Janszen, M1
Galarza, M1
Taha, A1
Durrer, A1
Mustaki, JP1
Baker, L1
Lee, M1
Regnard, C1
Crack, L1
Callin, S1
Bozkurt, P1
Bakan, M1
Kilinç, LT1
Moore, R1
Groves, D1
Hammond, C1
Leach, A1
Chester, MR1
Lambert, G1
Elam, M1
Friberg, P1
Lundborg, C2
Gao, S1
Bergquist, J1
Nitescu, P7
Manchikanti, L1
Damron, K1
Cash, K1
Manchukonda, R1
Pampati, V1
Giri, S1
Nixdorf, D1
Fischler, AH1
Gross, JB1
Kurihara, Y1
Ikegaki, J1
Kato, H1
Chigusa, S1
Kaetsu, H1
Vincenti, E1
Chiaranda, M1
Ambrosini, A1
Becagli, L1
De Salvia, D1
Maggino, T1
Marchesoni, D1
Loh, L1
Nathan, PW1
Schott, GD1
Coombs, DW2
Pageau, MG1
Saunders, RL2
Mroz, WT1
Saładajczyk, E1
Saładajczyk, G1
Crul, BJ3
van Dongen, RT3
Snijdelaar, DG1
Rutten, EH1
Cooper, MG1
Keneally, JP1
Kinchington, D1
Van Dongen, RTM1
Crul, BJP1
De Bock, M1
Goucke, R1
Ricci, V1
Dalpane, A1
Lolli, E1
Lafont, ND1
Legros, FJ1
Boogaerts, JG1
Verheijen, R1
Slappendel, R1
Jansen, JB1
Andersen, JS1
Markers, PI1
Valentin, N1
Wiersema, MJ1
Wiersema, LM1
Kurita, S1
Oda, Y1
Terai, T1
Yukioka, H1
Fujimori, M1
Asada, A1
Wagemans, MF1
van der Valk, P1
Spoelder, EM1
Zuurmond, WW1
de Lange, JJ1
Appelgren, L6
Curelaru, I6
Dahm, P2
Antila, H1
Kirvelä, O1
Serretta, R1
Sapio, M1
Calderone, L1
Soriano, C1
Ortiz, M1
Fas, MJ1
Escudero, A1
Roca, G2
Vidal, F2
Rykowski, JJ1
Hilgier, M1
Tsai, YC1
Wang, LK1
Chen, BS1
Chen, HP1
Mizuno, J1
Sugimoto, S1
Ikeda, M2
Machida, K1
Mikawa, Y1
Bleeker, CP1
Bremer, RC1
Dongelmans, DA1
Martin, R1
Schon, F1
Lamarche, Y1
Fernandes, L1
Goodwill, CJ1
Wright, MG1
James, CD1
Little, TF1
Du Pen, SL1
Kharasch, ED1
Williams, A1
Peterson, DG1
Sloan, DC1
Hasche-Klunder, H1
Krembs, AW1
Aguilar, JL1
Montes, A1
Samper, D1
Lema, MJ1
Shady, JA1
Zoll, JG1
West, CR1
Dionne, C1
King, HK1
Xiao, CS1
Wooten, DJ1
Cronen, MC2
Waldman, SD2
Hultman, E3
Linder, LE3
Sjöberg, M3
Hassenbusch, SJ1
Stanton-Hicks, MD1
Soukup, J1
Covington, EC1
Boland, MB1
Einarsson, S1
Berde, CB1
Sethna, NF1
Conrad, LS1
Hershenson, MB1
Shillito, J1
Duraj, M1
Kurzbauer, R1
Hunt, R1
Massolino, J1
Squier, R1
Morrow, JS1
Roman, R1
Newcombe, GN1
Rounsefell, BF1
Macintyre, P1
Fineman, SP1
Allen, ML1
Hardy, PA1
Wells, JC1
Ehring, E1
Boekstegers, A1
Lachance, D1
Savage, S1
Ragnarsson, TS1
Jensen, LE1
Müller, H1
Biscoping, J1
Gips, H1
Tilkes, F1
Strunz, P1
Hempelmann, G1
Bromage, PR1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective, Randomized, Double-Blinded, Allocation Concealed Study Comparing the Efficacy of Liposomal Bupivacaine Over Standard Bupivacaine Plus Dexamethasone in Quadriceps Sparing Femoral Nerve Block and Wound Infiltration for Primary Total Knee Arthro[NCT02624856]Phase 40 participants (Actual)Interventional2015-11-30Withdrawn (stopped due to Lack of funding)
A Double-blind, Randomized, Controlled, Pilot Study Comparing Three Different Anesthesic Techniques for Pregnant Women in Labour: Dural Puncture Epidural, Epidural and Combined Spinal Epidural. Evaluation of the Pain Control and the Hypotension Incidence [NCT05196256]Phase 390 participants (Anticipated)Interventional2022-06-30Not yet recruiting
A Randomized Double Blind Clinical Trial Comparing Programed Intermittent Epidural Boluses (PIEB) Versus Patient Controlled Epidural Analgesia (PCEA) With Epidural or Combined Spinal-epidural (CSE) Technique[NCT02768272]Phase 4240 participants (Actual)Interventional2016-03-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for bupivacaine and Pain, Intractable

ArticleYear
Treatment of medically refractory cancer pain with a combination of intrathecal neuromodulation and neurosurgical ablation: case series and literature review.
    Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:9

    Topics: Adolescent; Aged; Bone Neoplasms; Bupivacaine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell

2014
Continuous brachial plexus neural blockade in a child with intractable cancer pain.
    Journal of pain and symptom management, 1994, Volume: 9, Issue:4

    Topics: Bone Neoplasms; Brachial Plexus; Bupivacaine; Child; Drug Administration Schedule; Humans; Male; Ost

1994
[Continuous spinal analgesia in home care of oncologic pain].
    Minerva medica, 1995, Volume: 86, Issue:10

    Topics: Analgesics, Opioid; Bupivacaine; Clonidine; Home Infusion Therapy; Humans; Infusion Pumps, Implantab

1995
Efficacy and technical complications of long-term continuous intraspinal infusions of opioid and/or bupivacaine in refractory nonmalignant pain: a comparison between the epidural and the intrathecal approach with externalized or implanted catheters and in
    The Clinical journal of pain, 1998, Volume: 14, Issue:1

    Topics: Anesthetics, Local; Animals; Bupivacaine; Catheters, Indwelling; Humans; Infusion Pumps; Injections,

1998

Trials

9 trials available for bupivacaine and Pain, Intractable

ArticleYear
A randomized trial of breakthrough pain during combined spinal-epidural versus epidural labor analgesia in parous women.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:1

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca

2009
A randomized trial of breakthrough pain during combined spinal-epidural versus epidural labor analgesia in parous women.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:1

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca

2009
A randomized trial of breakthrough pain during combined spinal-epidural versus epidural labor analgesia in parous women.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:1

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca

2009
A randomized trial of breakthrough pain during combined spinal-epidural versus epidural labor analgesia in parous women.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:1

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca

2009
Perineural morphine in patients with chronic ischemic lower extremity pain: efficacy and long-term results.
    Journal of anesthesia, 2009, Volume: 23, Issue:1

    Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Isc

2009
Ureteric bupivicaine infusion for loin pain haematuria syndrome.
    Annals of the Royal College of Surgeons of England, 2010, Volume: 92, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Cystoscopy; Female; Follow-Up Studi

2010
Acute response to intracisternal bupivacaine in patients with refractory pain of the head and neck.
    The Journal of physiology, 2006, Jan-15, Volume: 570, Issue:Pt 2

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Biogenic Monoamines; Blood Pressure; Brain Stem;

2006
Therapeutic cervical medial branch blocks in managing chronic neck pain: a preliminary report of a randomized, double-blind, controlled trial: clinical trial NCT0033272.
    Pain physician, 2006, Volume: 9, Issue:4

    Topics: Adult; Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents; Arthralgia

2006
Continuous infusion of opioid and bupivacaine by externalized intrathecal catheters in long-term treatment of "refractory" nonmalignant pain.
    The Clinical journal of pain, 1998, Volume: 14, Issue:1

    Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Bupivacaine; Catheterization; Cohort Stu

1998
Efficacy of neurolytic celiac plexus block in varying locations of pancreatic cancer: influence on pain relief.
    Anesthesiology, 2000, Volume: 92, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Celiac Plexus; Female; Humans; Male

2000
Local anaesthetic nerve block in the treatment of intractable pain from osteoarthritis of the hip.
    Rheumatology and rehabilitation, 1978, Volume: 17, Issue:4

    Topics: Aged; Anesthesia, Local; Bupivacaine; Clinical Trials as Topic; Double-Blind Method; Female; Hip Joi

1978
Sufentanil citrate and morphine/bupivacaine as alternative agents in chronic epidural infusions for intractable non-cancer pain.
    Neurosurgery, 1991, Volume: 29, Issue:1

    Topics: Analgesia, Epidural; Analgesics; Bupivacaine; Drug Combinations; Drug Evaluation; Fentanyl; Humans;

1991

Other Studies

73 other studies available for bupivacaine and Pain, Intractable

ArticleYear
Evaluation of Fixed Intrathecal Bupivacaine Infusion Doses in the Oncologic Population.
    Neuromodulation : journal of the International Neuromodulation Society, 2020, Volume: 23, Issue:7

    Topics: Algorithms; Anesthetics, Local; Bupivacaine; Cancer Pain; Humans; Injections, Spinal; Morphine; Pain

2020
[Intracerebroventricular infusion of morphine, bupivacaine and clonidine for the management of refractory neoplasic pain in a palliative care setting : a case report].
    Revue medicale de Liege, 2021, Volume: 76, Issue:7-8

    Topics: Analgesics, Opioid; Bupivacaine; Clonidine; Humans; Infusions, Intraventricular; Male; Morphine; Pai

2021
Palliative care with cervical intrathecal infusion and external pump for a late-stage cancer patient with refractory pain: A case report.
    Medicine, 2018, Volume: 97, Issue:4

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Carcinoma,

2018
Urgent care peripheral nerve blocks for refractory trigeminal neuralgia.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:11

    Topics: Ambulatory Care; Anesthetics, Local; Bupivacaine; Humans; Lidocaine; Nerve Block; Outpatient Clinics

2018
Bupivacaine crystal deposits after long-term epidural infusion.
    Der Anaesthesist, 2013, Volume: 62, Issue:7

    Topics: Adenocarcinoma; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Crystalliz

2013
Intercostal administration of liposomal bupivacaine as a prognostic nerve block prior to phenol neurolysis for intractable chest wall pain.
    Journal of pain & palliative care pharmacotherapy, 2014, Volume: 28, Issue:1

    Topics: Anesthetics, Local; Bupivacaine; Female; Humans; Liposomes; Middle Aged; Nerve Block; Pain, Intracta

2014
Audit of intrathecal drug delivery for patients with difficult-to-control cancer pain shows a sustained reduction in pain severity scores over a 6-month period.
    Palliative medicine, 2015, Volume: 29, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Bupivacaine; Female; Humans; Infusion Pumps, Implantable; Injection

2015
Successful Management of Corneal Neuropathic Pain with Intrathecal Targeted Drug Delivery.
    Pain medicine (Malden, Mass.), 2016, Volume: 17, Issue:7

    Topics: Adult; Analgesics; Bupivacaine; Cervical Vertebrae; Cornea; Female; Fentanyl; Humans; Infusion Pumps

2016
The role of neurolytic celiac plexus block in the treatment of pancreatic cancer pain.
    Transplantation proceedings, 2008, Volume: 40, Issue:4

    Topics: Anesthetics, Local; Atropine; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Humans; Pain, Intra

2008
EUS-guided celiac plexus block for chronic pancreatitis: a placebo-controlled trial should be the first priority.
    Gastrointestinal endoscopy, 2010, Volume: 71, Issue:2

    Topics: Abdominal Pain; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Dose-Response Relationship, Drug;

2010
Comment on: Loin pain haematuria syndrome.
    Annals of the Royal College of Surgeons of England, 2010, Volume: 92, Issue:4

    Topics: Anesthetics, Local; Bupivacaine; Hematuria; Humans; Pain, Intractable; Syndrome

2010
Chronic, painful lower extremity wounds: postoperative pain management through the use of continuous infusion of regional anaesthesia supplied by a portable pump device.
    International wound journal, 2010, Volume: 7, Issue:3

    Topics: Analgesics; Anesthesia, Local; Bupivacaine; Debridement; Diabetic Foot; Humans; Infusion Pumps; Male

2010
A case of cancer pain management by long-term intrathecal PCA.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2010, Volume: 77, Issue:6

    Topics: Adult; Analgesia, Patient-Controlled; Bupivacaine; Female; Humans; Injections, Spinal; Ketamine; Mor

2010
Intrathecal infusion of bupivacaine and clonidine provides effective analgesia in a terminally ill child.
    Paediatric anaesthesia, 2012, Volume: 22, Issue:2

    Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Bupivacaine; Clonidine; Fatal Outcome; Humans; Infant

2012
Neurolytic celiac plexus block for visceral abdominal malignancy: is prior diagnostic block warranted?
    Anaesthesia and intensive care, 2002, Volume: 30, Issue:4

    Topics: Abdominal Neoplasms; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Ethanol;

2002
Opioid "holiday" following antagonist supported detoxification during general anesthesia improves opioid agonist response in a cancer patient with opioid addiction.
    Anesthesiology, 2003, Volume: 98, Issue:2

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bone Neoplasms; Bu

2003
Local anesthetic switching for intrathecal tachyphylaxis in cancer patients with pain.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:1

    Topics: Adult; Anesthetics, Local; Bupivacaine; Carcinoma, Small Cell; Endometrial Neoplasms; Female; Humans

2003
Epidural analgesia at end of life: facing empirical contraindications.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:6

    Topics: Abdominal Pain; Adrenergic alpha-Agonists; Adult; Analgesia, Epidural; Analgesics, Opioid; Anestheti

2003
Local anesthetic switching for intrathecal tachyphylaxis in cancer patients with pain.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:2

    Topics: Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Local; Bupivacaine; Humans; Injections,

2004
Application of a mandibular nerve block using an indwelling catheter for intractable cancer pain.
    Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:3

    Topics: Aged; Anesthetics, Local; Bupivacaine; Catheters, Indwelling; Facial Neoplasms; Female; Humans; Lido

2004
Spinal cord lesion after long-term intrathecal clonidine and bupivacaine treatment for the management of intractable pain.
    Pain, 2004, Volume: 109, Issue:1-2

    Topics: Analgesia, Epidural; Analgesics; Bupivacaine; Clonidine; Humans; Infusion Pumps, Implantable; Longit

2004
Correlation between withdrawal symptoms and medication pump residual volume in patients with implantable SynchroMed pumps.
    Neurosurgery, 2004, Volume: 55, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesics, Opioid; Baclofen; Bupivacaine; Clon

2004
Efficacy of intrathecal bupivacaine: how important is the flow rate?
    Pain medicine (Malden, Mass.), 2004, Volume: 5, Issue:3

    Topics: Aged; Anesthetics, Local; Bupivacaine; Dose-Response Relationship, Drug; Female; Humans; Infusion Pu

2004
Evolving spinal analgesia practice in palliative care.
    Palliative medicine, 2004, Volume: 18, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Analgesia; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Loc

2004
[Challenges in the treatment of pain in children with cancer and tunneling of epidural catheter for long term infusion].
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2005, Volume: 17, Issue:1

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bone Neoplasms; Bupivacaine; Catheteriz

2005
Temporary sympathectomy in the treatment of chronic refractory angina.
    Journal of pain and symptom management, 2005, Volume: 30, Issue:2

    Topics: Aged; Angina Pectoris; Bupivacaine; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pain, Intr

2005
Sympathetically maintained pain presenting first as temporomandibular disorder, then as parotid dysfunction.
    Journal (Canadian Dental Association), 2007, Volume: 73, Issue:2

    Topics: Adrenergic alpha-Agonists; Adult; Anesthetics, Local; Autonomic Nervous System Diseases; Bupivacaine

2007
Ultrasound-guided sciatic neuroma block for treatment of intractable stump pain.
    Journal of clinical anesthesia, 2007, Volume: 19, Issue:8

    Topics: Amputation Stumps; Anesthetics, Local; Bupivacaine; Female; Follow-Up Studies; Glucocorticoids; Huma

2007
[Intrathecal segmental analgesia with a single dose of bupivacaine for cancer pain in the abdominal wall].
    Masui. The Japanese journal of anesthesiology, 2008, Volume: 57, Issue:2

    Topics: Abdominal Neoplasms; Abdominal Pain; Abdominal Wall; Analgesia, Epidural; Bupivacaine; Colonic Neopl

2008
New trends for pain relief in gynaecologic oncology.
    European journal of gynaecological oncology, 1983, Volume: 4, Issue:2

    Topics: Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Epidural Space; Female; Genital Neoplasms, Female

1983
Regional hip blockade.
    Anaesthesia, 1983, Volume: 38, Issue:11

    Topics: Aged; Bupivacaine; Hip Joint; Humans; Nerve Block; Osteoarthritis; Pain, Intractable

1983
Pain due to lesions of central nervous system removed by sympathetic block.
    British medical journal (Clinical research ed.), 1981, Mar-28, Volume: 282, Issue:6269

    Topics: Adult; Aged; Autonomic Nerve Block; Bupivacaine; Central Nervous System Diseases; Female; Guanethidi

1981
Intraspinal narcotic tolerance: preliminary experience with continuous bupivicaine HCL infusion via implanted infusion device.
    The International journal of artificial organs, 1982, Volume: 5, Issue:6

    Topics: Artificial Organs; Bupivacaine; Humans; Infusions, Parenteral; Morphine; Pain, Intractable; Spinal C

1982
[Continuous extradural analgesia and morphine in the treatment of pain in cancer].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Jun-28, Volume: 37, Issue:19-20

    Topics: Adult; Anesthesia, Epidural; Bupivacaine; Dysgerminoma; Humans; Infusions, Parenteral; Male; Morphin

1982
Long-term continuous intrathecal administration of morphine and bupivacaine at the upper cervical level: access by a lateral C1-C2 approach.
    Anesthesia and analgesia, 1994, Volume: 79, Issue:3

    Topics: Bupivacaine; Carcinoma, Squamous Cell; Catheterization; Female; Humans; Injections, Spinal; Middle A

1994
Long-term intrathecal infusion of morphine and morphine/bupivacaine mixtures in the treatment of cancer pain: a retrospective analysis of 51 cases.
    Pain, 1993, Volume: 55, Issue:1

    Topics: Adult; Aged; Bupivacaine; Catheterization; Drug Combinations; Female; Humans; Injections, Spinal; Ma

1993
Continuous intrathecal analgesia with opioid/local anaesthetic mixture for cancer pain.
    Anaesthesia and intensive care, 1993, Volume: 21, Issue:2

    Topics: Adenocarcinoma; Analgesia; Anus Neoplasms; Bupivacaine; Drug Administration Schedule; Drug Combinati

1993
Use of liposome-associated bupivacaine in a cancer pain syndrome.
    Anaesthesia, 1996, Volume: 51, Issue:6

    Topics: Aged; Analgesia, Epidural; Anesthetics, Local; Bupivacaine; Drug Carriers; Humans; Liposomes; Lung N

1996
[Intrathecal administration of morphine and bupivacaine in the treatment of severe pain in chronic pancreatitis].
    Nederlands tijdschrift voor geneeskunde, 1996, Jul-06, Volume: 140, Issue:27

    Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Chronic Disease; Humans; Infusion Pumps;

1996
[Treatment of severe cancer pain via spinal catheters].
    Ugeskrift for laeger, 1996, Nov-11, Volume: 158, Issue:46

    Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Female; Humans; Infusion Pumps, Im

1996
Endosonography-guided celiac plexus neurolysis.
    Gastrointestinal endoscopy, 1996, Volume: 44, Issue:6

    Topics: Abdominal Neoplasms; Aged; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; En

1996
[Two cases of crush syndrome associated with intractable pain].
    Masui. The Japanese journal of anesthesiology, 1997, Volume: 46, Issue:4

    Topics: Adult; Analgesia, Epidural; Anesthetics, Local; Bupivacaine; Crush Syndrome; Fasciotomy; Female; Hum

1997
Neurohistopathological findings after continuous intrathecal administration of morphine or a morphine/bupivacaine mixture in cancer pain patients.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:8

    Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Dura Mater; Female; Humans; Infusi

1997
[Refractory pain in the head-neck region. Intrathecal pain relief requires professional expertise].
    Lakartidningen, 1998, Jan-14, Volume: 95, Issue:3

    Topics: Aged; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Female; Head and Neck

1998
Neurolytic thoracic paravertebral block in cancer pain. A clinical report.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:5

    Topics: Acute Disease; Adult; Aged; Analgesics; Anesthetics, Local; Bupivacaine; Chronic Disease; Female; Fo

1998
When all else fails: stepwise multiple solutions for a complex cancer pain syndrome.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1999, Volume: 7, Issue:1

    Topics: Aged; Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cholinesterase Inhibitors; Cl

1999
[A possibility of central diffusion during stellate ganglion blockade: "the sheath of the spinal rachidian nerve"].
    Revista espanola de anestesiologia y reanimacion, 1999, Volume: 46, Issue:3

    Topics: Adult; Anesthetics, Local; Apnea; Autonomic Nerve Block; Bupivacaine; Diffusion; Facial Paralysis; F

1999
Home-based patient-controlled epidural analgesia with bupivacaine for patients with intractable herpetic neuralgia.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2000, Volume: 99, Issue:8

    Topics: Adult; Aged; Analgesia, Epidural; Analgesia, Patient-Controlled; Anesthetics, Local; Bupivacaine; Fe

2000
[Usefulness of epidural administration of ketamine for relief of postherpetic neuralgia].
    Masui. The Japanese journal of anesthesiology, 2001, Volume: 50, Issue:8

    Topics: Aged; Analgesia, Epidural; Bupivacaine; Drug Therapy, Combination; Female; Herpes Zoster; Humans; In

2001
Inefficacy of high-dose transdermal fentanyl in a patient with neuropathic pain, a case report.
    European journal of pain (London, England), 2001, Volume: 5, Issue:3

    Topics: Administration, Cutaneous; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Breast Neopl

2001
[Use of frozen hypertonic saline in the treatment of pain].
    Annales de l'anesthesiologie francaise, 1979, Volume: 20, Issue:1

    Topics: Adult; Aged; Anesthesia, Conduction; Anesthesia, Epidural; Autonomic Nerve Block; Bupivacaine; Evalu

1979
Regional hip blockade. A simplified technique for the relief of intractable osteoarthritic pain.
    Anaesthesia, 1976, Volume: 31, Issue:8

    Topics: Autonomic Nerve Block; Bupivacaine; Hip Joint; Humans; Obturator Nerve; Osteoarthritis; Pain, Intrac

1976
Chronic epidural bupivacaine-opioid infusion in intractable cancer pain.
    Pain, 1992, Volume: 49, Issue:3

    Topics: Analgesia, Epidural; Blood Pressure; Bupivacaine; Drug Therapy, Combination; Humans; Narcotics; Neop

1992
Interpleural analgesia through a DuPen catheter for lung cancer pain.
    Cancer, 1992, Dec-01, Volume: 70, Issue:11

    Topics: Bupivacaine; Catheterization; Humans; Lung Neoplasms; Male; Middle Aged; Pain, Intractable; Pleura

1992
Management of intractable back pain from caudal ependymoma with spinal methylprednisolone, bupivacaine and morphine.
    Pain, 1992, Volume: 48, Issue:2

    Topics: Adult; Bupivacaine; Cauda Equina; Drug Combinations; Ependymoma; Female; Humans; Injections, Spinal;

1992
Tumour invasion of the brachial plexus: management of pain with intrapleural analgesia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:5 Pt 1

    Topics: Adenocarcinoma; Aged; Analgesia; Brachial Plexus; Bupivacaine; Humans; Male; Neoplasm Invasiveness;

1992
[Epidural administration of bupivacaine in glycerine solution can prolong analgesia].
    Ma zui xue za zhi = Anaesthesiologica Sinica, 1992, Volume: 30, Issue:1

    Topics: Adult; Analgesia, Epidural; Bupivacaine; Female; Glycerol; Humans; Injections, Epidural; Male; Middl

1992
Cervical steroid epidural nerve blocks in the palliation of pain secondary to intractable tension-type headaches.
    Journal of pain and symptom management, 1990, Volume: 5, Issue:6

    Topics: Analgesia, Epidural; Bupivacaine; Follow-Up Studies; Headache; Humans; Methylprednisolone; Nerve Blo

1990
Long-term, open catheterization of the spinal subarachnoid space for continuous infusion of narcotic and bupivacaine in patients with "refractory" cancer pain. A technique of catheterization and its problems and complications.
    The Clinical journal of pain, 1991, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia; Anesthesia, Local; Anti-Bacterial Agents; Bu

1991
Long-term intrathecal morphine and bupivacaine in "refractory" cancer pain. I. Results from the first series of 52 patients.
    Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Bupivacaine; Female; Humans; Injections, Spinal; Male; Middle Aged;

1991
Epidural versus intrathecal morphine-bupivacaine: assessment of consecutive treatments in advanced cancer pain.
    Journal of pain and symptom management, 1990, Volume: 5, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Bupivacaine; Dose-Response Relationship, Drug;

1990
Subarachnoid bupivacaine analgesia for seven months for a patient with a spinal cord tumor.
    Anesthesiology, 1990, Volume: 72, Issue:6

    Topics: Adult; Analgesia; Astrocytoma; Bupivacaine; Female; Humans; Pain, Intractable; Spinal Cord Neoplasms

1990
[Anesthesia of the celiac plexus in analgesia in cases of inoperable epigastric tumors].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1985, Feb-15, Volume: 38, Issue:4

    Topics: Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Humans; Pain, Intractable; Palliative Care; Pancr

1985
Spinal bupivacaine for the pain of cancer.
    The Medical journal of Australia, 1989, Mar-20, Volume: 150, Issue:6

    Topics: Adult; Aged; Anesthesia, Spinal; Bupivacaine; Humans; Middle Aged; Neoplasms; Pain, Intractable; Pal

1989
Pain therapy for pancreatic carcinoma with neurolytic celiac plexus block.
    Connecticut medicine, 1989, Volume: 53, Issue:5

    Topics: Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Humans; Pain, Intractable; Palliative Care; Pancr

1989
Pain relief with bupivacaine given through a sciatic nerve catheter.
    Anaesthesia and intensive care, 1989, Volume: 17, Issue:3

    Topics: Adult; Bupivacaine; Catheterization; Humans; Leg; Male; Pain, Intractable; Palliative Care; Sciatic

1989
Long-term post-thoracotomy cancer pain management with interpleural bupivacaine.
    Anesthesia and analgesia, 1989, Volume: 68, Issue:5

    Topics: Bupivacaine; Female; Humans; Lung Neoplasms; Middle Aged; Neoplasm Metastasis; Pain, Intractable; Pa

1989
Subcutaneous tunneled intrapleural catheters in the long-term relief of right upper quadrant pain of malignant origin.
    Journal of pain and symptom management, 1989, Volume: 4, Issue:2

    Topics: Adult; Bupivacaine; Catheters, Indwelling; Female; Humans; Injections; Liver Neoplasms; Nerve Block;

1989
Coeliac plexus block and cephalic spread of injectate.
    Annals of the Royal College of Surgeons of England, 1989, Volume: 71, Issue:1

    Topics: Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Contrast Media; Ethanol; Extravasation of Diagnos

1989
[Morphologic and histologic changes caused by continuous peridural analgesia in a cancer patient].
    Regional-Anaesthesie, 1986, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Anesthesia, Epidural; Bupivacaine; Catheters, Indwelling; Colonic Neoplasms; Fentany

1986
Intrathecal morphine tolerance: use of intrathecal clonidine, DADLE, and intraventricular morphine.
    Anesthesiology, 1985, Volume: 62, Issue:3

    Topics: Adenocarcinoma; Bupivacaine; Clonidine; Combined Modality Therapy; Double-Blind Method; Drug Therapy

1985
[Hygienic relations and stability of drugs in peridural long-term infusion with implanted or external pumps].
    Der Anaesthesist, 1985, Volume: 34, Issue:5

    Topics: Abscess; Anesthesia, Epidural; Bacterial Infections; Bacteriological Techniques; Bupivacaine; Drug C

1985
Nerve physiology and control of pain.
    The Orthopedic clinics of North America, 1973, Volume: 4, Issue:4

    Topics: Adult; Aged; Anesthesia, Local; Arm; Bupivacaine; Denervation; Electric Stimulation; Epinephrine; Hu

1973