bupivacaine has been researched along with Pain, Chronic in 35 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the effectiveness of hysteroscopic-guided pertubal diluted bupivacaine infusion for endometriosis-associated chronic pelvic pain (CPP)." | 9.20 | A randomized, placebo-controlled, double-blind study of hysteroscopic-guided pertubal diluted bupivacaine infusion for endometriosis-associated chronic pelvic pain. ( Mousa, S; Shokeir, T, 2015) |
| "Bupivacaine is a longer-lasting local anesthetic, and a film-forming formulation allows easy and durable application to the affected skin." | 6.66 | Postherpetic Neuralgia: Current Evidence on the Topical Film-Forming Spray with Bupivacaine Hydrochloride and a Review of Available Treatment Strategies. ( Anya, A; Berger, AA; Cornett, EM; Fortier, L; Herron, EW; Kassem, H; Kaye, AD; Ngo, AL; Oh, JH; Sanchez, MG; Urits, I; Urman, RD; Viswanath, O; Yilmaz, M, 2020) |
| "Chronic chest pain is a debilitating condition that is poorly treated, resulting in opioid dependence and significantly decreased quality of life." | 5.51 | Repeated Intercostal Nerve Blocks With Liposomal Bupivacaine for Chronic Chest Pain: A Case Report. ( Verdecchia, N; Visoiu, M, 2019) |
| "To assess the effectiveness of hysteroscopic-guided pertubal diluted bupivacaine infusion for endometriosis-associated chronic pelvic pain (CPP)." | 5.20 | A randomized, placebo-controlled, double-blind study of hysteroscopic-guided pertubal diluted bupivacaine infusion for endometriosis-associated chronic pelvic pain. ( Mousa, S; Shokeir, T, 2015) |
| "Multimodal IT treatment with morphine, bupivacaine and clonidine is effective and safe for treating refractory cancer pain in the terminal phase of disease." | 3.85 | Multimodal intrathecal analgesia in refractory cancer pain. ( Kallewaard, JW; Kramp-Hendriks, BJ; Mastenbroek, TC; Vonk, JM, 2017) |
| "Postmastectomy pain is chronic pain that occurs in females after breast surgeries." | 3.30 | Comparison of different volumes spread of erector spinae block in postmastectomy pain syndrome management: a prospective randomized comparative study. ( Abdelghaffar, NA; Amer, GF, 2023) |
| "Thirty-one patients with chronic pain (trapezius myalgia) and CS after whiplash." | 2.87 | Central Sensitization Is Modulated Following Trigger Point Anesthetization in Patients with Chronic Pain from Whiplash Trauma. A Double-Blind, Placebo-Controlled, Crossover Study. ( Freeman, MD; Nystrom, NA, 2018) |
| "Peripheral neuropathic pain (PNP) associated with trauma is often refractory to treatment." | 2.82 | Study protocol for a pilot, randomised, double-blinded, placebo controlled trial of perineural local anaesthetics and steroids for chronic post-traumatic neuropathic pain in the ankle and foot: the PREPLANS study. ( Alvi, S; Bhatia, A; Bril, V; Brull, RT; Davis, AM; Gandhi, R; Lau, J; Mahomed, N; Perruccio, A; Wijeysundera, D, 2016) |
| "The aim of this study was to compare postoperative pain levels following intermittent regional administration of bupivacaine via a catheter placed in the rectus sheath or subcutaneously at abdominal surgery through midline incisions." | 2.78 | Randomized clinical trial of subcutaneous versus interfascial bupivacaine for pain control after midline laparotomy. ( Aminian, A; Ghaffari, MH; Hosseini Araghi, N; Khorgami, Z; Mollahosseini, F; Nasiri, S; Shoar, S, 2013) |
| "The frequency of neuropathic pain was assessed using the Douleur Neuropathique 4-question survey (DN4) in the first and second postoperative months." | 2.78 | Effect of the addition of clonidine to locally administered bupivacaine on acute and chronic postmastectomy pain. ( Abdel-Ghaffar, HS; Mohamed, SA, 2013) |
| "Ketamine is an effective and safe multimodal analgesic in patients undergoing breast surgery, administered both intravenously and when added to bupivacaine in paravertebral blocks." | 2.72 | The Effect of Ketamine on Acute and Chronic Wound Pain in Patients Undergoing Breast Surgery: A Meta-Analysis and Systematic Review. ( Bi, Y; Liu, B; Ma, J; Ye, Y; Zhang, X; Zhu, Y, 2021) |
| "Bupivacaine is a longer-lasting local anesthetic, and a film-forming formulation allows easy and durable application to the affected skin." | 2.66 | Postherpetic Neuralgia: Current Evidence on the Topical Film-Forming Spray with Bupivacaine Hydrochloride and a Review of Available Treatment Strategies. ( Anya, A; Berger, AA; Cornett, EM; Fortier, L; Herron, EW; Kassem, H; Kaye, AD; Ngo, AL; Oh, JH; Sanchez, MG; Urits, I; Urman, RD; Viswanath, O; Yilmaz, M, 2020) |
| "TAP blocks can be extrapolated for treating abdominal pain beyond acute settings." | 1.56 | Transversus Abdominis Plane Block as a Treatment Modality for Chronic Abdominal Pain. ( Abd-Elsayed, A; Falls, C; Luo, S, 2020) |
| "The chronic cervical facet joint pain was diagnosed with cervical facet joint nerve blocks at a prevalence of 49." | 1.56 | Assessment of Prevalence of Cervical Facet Joint Pain with Diagnostic Cervical Medial Branch Blocks: Analysis Based on Chronic Pain Model. ( Cash, KA; Hirsch, JA; Kaye, AD; Kosanovic, R; Manchikanti, L; Pampati, V; Soin, A, 2020) |
| "Approaches used to treat chronic pain outside the eye can be applied to ocular pain that is not responsive to traditional therapies." | 1.56 | Oral Gabapentinoids and Nerve Blocks for the Treatment of Chronic Ocular Pain. ( Felix, ER; Galor, A; Horn, DB; Levitt, RC; Sarantopoulos, CD; Small, LR, 2020) |
| "Chronic chest pain is a debilitating condition that is poorly treated, resulting in opioid dependence and significantly decreased quality of life." | 1.51 | Repeated Intercostal Nerve Blocks With Liposomal Bupivacaine for Chronic Chest Pain: A Case Report. ( Verdecchia, N; Visoiu, M, 2019) |
| "Hemiplegic shoulder pain is the most common pain condition after stroke." | 1.46 | Suprascapular nerve block for the treatment of hemiplegic shoulder pain in patients with long-term chronic stroke: a pilot study. ( Bonazza, S; Chemello, E; Gandolfi, M; Lobba, D; Martini, A; Parolini, M; Picelli, A; Polati, E; Schweiger, V; Smania, N, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 23 (65.71) | 24.3611 |
| 2020's | 12 (34.29) | 2.80 |
| Authors | Studies |
|---|---|
| Scarfo, KA | 1 |
| Leary, OP | 1 |
| Gaudet, D | 1 |
| Carayannopoulos, AG | 1 |
| Grande, G | 1 |
| Fusco, P | 1 |
| Stecco, C | 1 |
| Petroni, GM | 1 |
| Ciaschi, W | 1 |
| Marinangeli, F | 1 |
| Ferraro, MC | 1 |
| Cashin, AG | 1 |
| Wand, BM | 1 |
| Smart, KM | 1 |
| Berryman, C | 1 |
| Marston, L | 1 |
| Moseley, GL | 1 |
| McAuley, JH | 1 |
| O'Connell, NE | 1 |
| Abdelghaffar, NA | 1 |
| Amer, GF | 1 |
| Kvarstein, G | 1 |
| Högström, H | 1 |
| Allen, SM | 1 |
| Rosland, JH | 1 |
| Benkli, B | 1 |
| Ansoanuur, G | 1 |
| Hernandez, N | 1 |
| Hayek, SM | 2 |
| McEwan, MT | 1 |
| Veizi, E | 1 |
| DeLozier, SJ | 1 |
| Pogrebetskaya, M | 1 |
| Ngo, AL | 1 |
| Urits, I | 2 |
| Yilmaz, M | 1 |
| Fortier, L | 1 |
| Anya, A | 1 |
| Oh, JH | 1 |
| Berger, AA | 1 |
| Kassem, H | 1 |
| Sanchez, MG | 1 |
| Kaye, AD | 3 |
| Urman, RD | 1 |
| Herron, EW | 1 |
| Cornett, EM | 1 |
| Viswanath, O | 2 |
| Manchikanti, L | 2 |
| Knezevic, NN | 1 |
| Parr, A | 1 |
| Sanapati, M | 1 |
| Hirsch, JA | 2 |
| Abd-Elsayed, A | 2 |
| Luo, S | 1 |
| Falls, C | 1 |
| Bi, Y | 1 |
| Ye, Y | 1 |
| Zhu, Y | 1 |
| Ma, J | 1 |
| Zhang, X | 1 |
| Liu, B | 1 |
| Kosanovic, R | 1 |
| Cash, KA | 1 |
| Pampati, V | 1 |
| Soin, A | 1 |
| Malyuk, D | 1 |
| Nystrom, NA | 1 |
| Freeman, MD | 1 |
| Picelli, A | 1 |
| Bonazza, S | 1 |
| Lobba, D | 1 |
| Parolini, M | 1 |
| Martini, A | 1 |
| Chemello, E | 1 |
| Gandolfi, M | 1 |
| Polati, E | 1 |
| Smania, N | 1 |
| Schweiger, V | 1 |
| Mastenbroek, TC | 1 |
| Kramp-Hendriks, BJ | 1 |
| Kallewaard, JW | 1 |
| Vonk, JM | 1 |
| Maranto, CJ | 1 |
| Strickland, NR | 1 |
| Goree, JH | 1 |
| Kanai, A | 1 |
| Okamoto, T | 1 |
| Hayashi, N | 1 |
| Shimao, J | 1 |
| Nagahara, Y | 1 |
| Fujii, K | 1 |
| Petro, J | 1 |
| Aner, M | 1 |
| Small, LR | 1 |
| Galor, A | 1 |
| Felix, ER | 1 |
| Horn, DB | 1 |
| Levitt, RC | 1 |
| Sarantopoulos, CD | 1 |
| Visoiu, M | 1 |
| Verdecchia, N | 1 |
| Khorgami, Z | 1 |
| Shoar, S | 1 |
| Hosseini Araghi, N | 1 |
| Mollahosseini, F | 1 |
| Nasiri, S | 1 |
| Ghaffari, MH | 1 |
| Aminian, A | 1 |
| Wang, L | 1 |
| Bauer, M | 1 |
| Curry, R | 1 |
| Larsson, A | 1 |
| Sessler, DI | 1 |
| Eisenach, JC | 1 |
| De Andres, J | 1 |
| Asensio-Samper, JM | 1 |
| Fabregat-Cid, G | 1 |
| Yamamoto, T | 1 |
| Desai, A | 1 |
| Saha, S | 1 |
| Sharma, N | 1 |
| Huckerby, L | 1 |
| Houghton, R | 1 |
| Anderson, ES | 1 |
| Hodell, E | 1 |
| Mantuani, D | 1 |
| Fahimi, J | 1 |
| Pampalone, I | 1 |
| Nagdev, A | 1 |
| Shokeir, T | 1 |
| Mousa, S | 1 |
| Kim, T | 1 |
| Seol, DR | 1 |
| Hahm, SC | 1 |
| Ko, C | 1 |
| Kim, EH | 1 |
| Chun, K | 1 |
| Kim, J | 1 |
| Lim, TH | 1 |
| Bhatia, A | 1 |
| Bril, V | 1 |
| Brull, RT | 1 |
| Perruccio, A | 1 |
| Wijeysundera, D | 1 |
| Alvi, S | 1 |
| Lau, J | 1 |
| Gandhi, R | 1 |
| Mahomed, N | 1 |
| Davis, AM | 1 |
| Sarı, S | 1 |
| Aydın, ON | 1 |
| Turan, Y | 1 |
| Özlülerden, P | 1 |
| Efe, U | 1 |
| Kurt Ömürlü, İ | 1 |
| Veizi, IE | 1 |
| Narouze, S | 1 |
| Pope, JE | 1 |
| Mekhail, N | 1 |
| Gimeno-García, AZ | 1 |
| Elwassief, A | 1 |
| Paquin, SC | 1 |
| Sahai, AV | 1 |
| Thomassen, I | 1 |
| van Suijlekom, JA | 1 |
| van de Gaag, A | 1 |
| Ponten, JE | 1 |
| Nienhuijs, SW | 1 |
| Mohamed, SA | 1 |
| Abdel-Ghaffar, HS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cryoneurolysis as a Drug Free Novel Treatment for Knee and Shoulder Pain Impairing Inpatient Neurological Rehabilitation[NCT05674604] | 25 participants (Anticipated) | Observational | 2022-10-10 | Recruiting | |||
| Comparison of PECS II Block and Combined Serratus Anterior Plane Block to Reduce Acute Pain After Mastectomy[NCT05961735] | 60 participants (Anticipated) | Observational | 2023-08-01 | Not yet recruiting | |||
| Effect of Trigeminal Nerve Stimulation on Subbasal Corneal Nerve Plexus Density and Chronic Ocular Pain in Patients With Dry Eye[NCT04648085] | 7 participants (Actual) | Interventional | 2021-02-03 | Completed | |||
| Effect of Intrathecal Ketorolac on Mechanical Hypersensitivity After Total Hip Arthroplasty[NCT00621530] | Phase 2 | 62 participants (Actual) | Interventional | 2008-03-31 | Terminated (stopped due to Terminated due to discontinuation of Acular PF (investigational medication)) | ||
| A Pilot Randomized Controlled Trial of Efficacy of Perineural Local Anesthetics and Steroids for Chronic Post-traumatic Neuropathic Pain in the Ankle and the Foot: The PREPLAN Study[NCT02680548] | Early Phase 1 | 8 participants (Actual) | Interventional | 2015-11-30 | Completed | ||
| A Randomized Double Blind Cross-over Trial of Continuous Intrathecal Infusion for Assessing Patients With Chronic Non-cancer Pain Who Would Benefit From Treatment With Intrathecal Drug Delivery System (IDDS) Implant[NCT03523000] | Phase 4 | 36 participants (Actual) | Interventional | 2017-10-18 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Hyperalgesia (using a von Frey filament) and allodynia (using a cotton swab) were evaluated around the surgical site 48 hours after surgery. (NCT00621530)
Timeframe: 48 hours
| Intervention | area in centimeters squared (Median) |
|---|---|
| Ketorolac | 0 |
| Placebo | 0 |
Pain was assessed 2 days, and 2 and 6 months after surgery using a validated questionnaire wherein subjects rate the degree to which adjectives describe the emotional component of their pain experience. This is termed the McGill Pain Affective Score and is scored from 0 to 12 with 12 being the highest pain emotional impact. (NCT00621530)
Timeframe: 6 months
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Postoperative: 2 days | Postoperative: 2 months | Postoperative: 6 months | |
| Ketorolac | 2.3 | 0.4 | 0.1 |
| Placebo | 2.3 | 0.5 | 0.4 |
Pain was assessed 2 days and 2 and 6 months after surgery using a validated questionnaire wherein subjects rate the degree to which adjectives describe the intensity of their pain experience. This is termed the McGill Pain Intensity Score and is scored from 0 to 33 with 33 being the highest pain intensity. (NCT00621530)
Timeframe: 6 months
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Postoperative: 2 days | Postoperative: 2 months | Postoperative: 6 months | |
| Ketorolac | 11 | 2.3 | 1.4 |
| Placebo | 10 | 3.1 | 1.2 |
Pain was assessed 2 days, and 2 and 6 months after surgery using a validated questionnaire to assess the degree of neuropathic characteristics of pain. This is termed the Neuropathic Pain Symptom Inventory which is scored 0-100 with 100 being the worst possible pain. (NCT00621530)
Timeframe: 6 months
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Postoperative: 2 days | Postoperative: 2 months | Postoperative: 6 months | |
| Ketorolac | 13 | 2.9 | 2.4 |
| Placebo | 21 | 4.5 | 1.4 |
Pain was assessed preoperatively, 2 days, and 2 and 6 months after surgery using a 0-10 (10 being worse) verbal Present Pain Intensity (PPI) scale (NCT00621530)
Timeframe: 6 months
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| Preoperative | Postoperative: 2 days | Postoperative: 2 months | Postoperative: 6 months | |
| Ketorolac | 1.7 | 2.1 | 0.6 | 0.4 |
| Placebo | 1.6 | 2.5 | 0.2 | 0.1 |
AE is any untoward medical occurrence in the patient which does not necessarily have a causal relationship with this infusion treatment (NCT03523000)
Timeframe: Assessing any AEs that occur from baseline (Day 1) through the 12-month post-implant clinic follow up
| Intervention | Adverse events (Number) |
|---|---|
| All Study Participants | 9 |
Number of participants that had increases or decreases in the dose or frequency of pain medication (NCT03523000)
Timeframe: Assessing any changes in pain medications from baseline (Day 1) through the 12-month post-implant clinic follow up
| Intervention | Participants (Count of Participants) |
|---|---|
| Active Solution Followed by Inactive Place Solution | 0 |
| Inactive Placebo Solution Followed by Active Solution | 3 |
Numerical Rating Scale is an 11-point pain scale whereby 0 signifies no pain and 10 the worse pain ever (NCT03523000)
Timeframe: Comparing change in NRS from baseline (Day 1) to: end of intrathecal infusion of solution 1 (Day 2), end of intrathecal infusion of solution 2 (Day 3)
| Intervention | Score on a scale (Mean) | ||
|---|---|---|---|
| Baseline | End of intrathecal infusion of solution (Day 2) | End of intrathecal infusion of solution (Day 3) | |
| Active Solution Followed by Inactive Placebo Solution | 6.5 | 3.67 | 4.25 |
| Inactive Placebo Solution Followed by Active Solution | 6.75 | 3.69 | 6.73 |
Numerical Rating Scale is an 11-point pain scale whereby 0 signifies no pain and 10 the worse pain ever (NCT03523000)
Timeframe: Comparing change in NRS from baseline (Day 1) to: end of intrathecal infusion of solution 1 (Day 2), end of intrathecal infusion of solution 2 (Day 3)
| Intervention | Score on a scale (Mean) | ||
|---|---|---|---|
| Baseline | End of intrathecal infusion of solution (Day 2) | End of intrathecal infusion of solution (Day 3) | |
| Active Solution Followed by Inactive Placebo Solution | 8.40 | 4.13 | 4.38 |
| Inactive Placebo Solution Followed by Active Solution | 8.00 | 4.19 | 6.73 |
Oswestry Disability Index (ODI) This scale based on a questionnaire of activities measures the impact of pain on multiple factors within a patient's daily life. Higher values represent worse outcomes, or a higher impact from pain on the patient's daily life. The total score range is 0-50. Subcategories include: 0-4: no disability. 5-14: mild disability. 15-24: moderate disability. 25-34: sever disability. 35-50: completely disabled. (NCT03523000)
Timeframe: Comparing change in ODI from baseline (Day 1) to: end of intrathecal infusion of solution 2 (Day 3)
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Baseline | End of intrathecal infusion of solution (Day 3) | |
| Active Solution Followed by Inactive Placebo Solution | 27.13 | 20.38 |
| Inactive Placebo Solution Followed by Active Solution | 26.81 | 27.07 |
The painDETECT questionnaire was specifically developed to detect neuropathic pain components in adult patients with low back pain. PainDETECT is a scale 0 to 38, with 0 being no disability to 38 being max disability. (NCT03523000)
Timeframe: Comparing change in PainDETECT from baseline (Day 1) to: end of intrathecal infusion of solution 2 (Day 3)
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Baseline | End of intrathecal infusion of solution (Day 3) | |
| Active Solution Followed by Inactive Placebo Solution | 16.4 | 10.81 |
| Inactive Placebo Solution Followed by Active Solution | 13.31 | 15.27 |
The painDETECT questionnaire was specifically developed to detect neuropathic pain components in adult patients with low back pain. PainDETECT is a scale of 0 to 35, with 0 being no disability to 35 being max disability. (NCT03523000)
Timeframe: Comparing change in PainDETECT from baseline (Day 1) to: end of intrathecal infusion of solution 2 (Day 3)
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Baseline | End of intrathecal infusion of solution (Day 3) | |
| Active Solution Followed by Inactive Placebo Solution | 15.047 | 10.19 |
| Inactive Placebo Solution Followed by Active Solution | 11.94 | 14.27 |
Patient Global Impression of Change (PGIC) scale is a seven-point single-item scale ranging from 7 'very much worse' to 1 'very much improved'. (NCT03523000)
Timeframe: Comparing change in PGIC from end of intrathecal infusion of solution 1 (Day 2), to end of intrathecal infusion of solution 2 (Day 3)
| Intervention | score on a scale (Mean) | |
|---|---|---|
| End of intrathecal infusion of solution (Day 2) | End of intrathecal infusion of solution (Day 3) | |
| Active Solution Followed by Inactive Placebo Solution | 4.53 | 4.07 |
| Inactive Placebo Solution Followed by Active Solution | 4.66 | 2.48 |
TSQ is a questionnaire to rate level of satisfaction or dissatisfaction with the Intrathecal Drug Delivery- patients were asked preference for either intrathecal solution. Patient preferences for each solution were measured. This data represents the total number of patient's that received a trial and the total number of patients who preferred each solution. Higher values indicate a greater number of study participants preferred a specific arm. Patients with no preference are listed separately. (NCT03523000)
Timeframe: Up to one year
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Intrathecal Infusion 1- Sequence 1 | Intrathecal Infusion 2- Sequence 1 | No preference- Sequence1 | Intrathecal Infusion 1- Sequence 2 | Intrathecal Infusion 2- Sequence 2 | No preference- Sequence 2 | |
| All Study Participants | 11 | 2 | 2 | 5 | 11 | 0 |
5 reviews available for bupivacaine and Pain, Chronic
| Article | Year |
|---|---|
Interventions for treating pain and disability in adults with complex regional pain syndrome- an overview of systematic reviews.
Topics: Adult; Bupivacaine; Chronic Pain; Complex Regional Pain Syndromes; Humans; Quality of Life; Systemat | 2023 |
Postherpetic Neuralgia: Current Evidence on the Topical Film-Forming Spray with Bupivacaine Hydrochloride and a Review of Available Treatment Strategies.
Topics: Analgesics; Analgesics, Opioid; Bupivacaine; Chronic Pain; Health Care Costs; Herpes Zoster; Humans; | 2020 |
Does Epidural Bupivacaine with or Without Steroids Provide Long-Term Relief? A Systematic Review and Meta-analysis.
Topics: Anesthetics, Local; Back Pain; Bupivacaine; Chronic Pain; Humans; Injections, Epidural; Randomized C | 2020 |
The Effect of Ketamine on Acute and Chronic Wound Pain in Patients Undergoing Breast Surgery: A Meta-Analysis and Systematic Review.
Topics: Acute Pain; Analgesics; Analgesics, Opioid; Breast Neoplasms; Bupivacaine; Chronic Pain; Female; Hum | 2021 |
Intrathecal delivery of analgesics.
Topics: Analgesics, Opioid; Baclofen; Bupivacaine; Catheters, Indwelling; Chronic Pain; Clonidine; Drug Deli | 2014 |
13 trials available for bupivacaine and Pain, Chronic
| Article | Year |
|---|---|
Comparison of different volumes spread of erector spinae block in postmastectomy pain syndrome management: a prospective randomized comparative study.
Topics: Breast Neoplasms; Bupivacaine; Chronic Pain; Female; Humans; Mastectomy; Methylprednisolone; Prospec | 2023 |
Cryoneurolysis for cervicogenic headache - a double blinded randomized controlled study.
Topics: Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Chronic Pain; Double-Blind Method; Female | 2019 |
Effects of Bupivacaine on Opioid Patient-Controlled Intrathecal Analgesia in Chronic Pain Patients Implanted with Drug Delivery Systems.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Chronic Pain; Do | 2021 |
Central Sensitization Is Modulated Following Trigger Point Anesthetization in Patients with Chronic Pain from Whiplash Trauma. A Double-Blind, Placebo-Controlled, Crossover Study.
Topics: Adult; Anesthetics, Local; Bupivacaine; Central Nervous System Sensitization; Chronic Pain; Cross-Ov | 2018 |
Short-term results of intrathecal injection of low-dose bupivacaine in outpatients with chronic low back and lower extremity pain.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Chronic Pain; Dose-Response Relatio | 2019 |
Randomized clinical trial of subcutaneous versus interfascial bupivacaine for pain control after midline laparotomy.
Topics: Administration, Cutaneous; Administration, Rectal; Adult; Analgesics, Opioid; Anesthetics, Local; Bu | 2013 |
Intrathecal ketorolac does not improve acute or chronic pain after hip arthroplasty: a randomized controlled trial.
Topics: Acute Pain; Anesthesia, Spinal; Arthroplasty, Replacement, Hip; Bupivacaine; Chronic Pain; Double-Bl | 2014 |
The short- and medium-term effectiveness of CT-guided selective cervical nerve root injection for pain and disability.
Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Cervical Cord; Chronic Pain; Dexamethasone; Female; Hu | 2014 |
Pilot study of ultrasound-guided corticosteroid hip injections by emergency physicians.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Chronic Pain; Drug Therapy, Combina | 2014 |
A randomized, placebo-controlled, double-blind study of hysteroscopic-guided pertubal diluted bupivacaine infusion for endometriosis-associated chronic pelvic pain.
Topics: Adult; Anesthetics, Local; Bupivacaine; Chronic Pain; Double-Blind Method; Egypt; Endometriosis; Fem | 2015 |
Study protocol for a pilot, randomised, double-blinded, placebo controlled trial of perineural local anaesthetics and steroids for chronic post-traumatic neuropathic pain in the ankle and foot: the PREPLANS study.
Topics: Anesthetics, Local; Ankle; Ankle Injuries; Bupivacaine; Chronic Pain; Double-Blind Method; Feasibili | 2016 |
Which one is more effective for the clinical treatment of chronic pain in knee osteoarthritis: radiofrequency neurotomy of the genicular nerves or intra-articular injection?
Topics: Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthetics, Local; Arthralgia; Betamethaso | 2018 |
Effect of the addition of clonidine to locally administered bupivacaine on acute and chronic postmastectomy pain.
Topics: Acute Pain; Administration, Topical; Adult; Analgesics; Anesthetics, Local; Breast Neoplasms; Bupiva | 2013 |
17 other studies available for bupivacaine and Pain, Chronic
| Article | Year |
|---|---|
Transition from Compounded to Monotherapy Intrathecal Pain Medication Reduces Drug Costs: Retrospective Analysis of Patient Billing Data.
Topics: Bupivacaine; Chronic Pain; Humans; Hydromorphone; Pharmaceutical Preparations; Retrospective Studies | 2021 |
ESP block and chronic pain: the dark side of the moon.
Topics: Bupivacaine; Chronic Pain; Humans; Nerve Block; Pain, Postoperative | 2022 |
Case Report: Treatment of Refractory Post-Surgical Neuralgia With Erector Spinae Plane Block.
Topics: Aged; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Chronic Pain; Dexamethasone; Humans | 2020 |
Transversus Abdominis Plane Block as a Treatment Modality for Chronic Abdominal Pain.
Topics: Abdominal Muscles; Abdominal Pain; Adult; Anesthetics, Local; Bupivacaine; Chronic Pain; Female; Hum | 2020 |
Assessment of Prevalence of Cervical Facet Joint Pain with Diagnostic Cervical Medial Branch Blocks: Analysis Based on Chronic Pain Model.
Topics: Adult; Anesthetics, Local; Arthralgia; Bupivacaine; Chronic Pain; Female; Humans; Lidocaine; Male; M | 2020 |
Efficacy of Transversus Abdominis Plane Steroid Injection for Treating Chronic Abdominal Pain.
Topics: Abdominal Muscles; Abdominal Pain; Adult; Aged; Anesthetics, Local; Bupivacaine; Chronic Pain; Femal | 2018 |
Suprascapular nerve block for the treatment of hemiplegic shoulder pain in patients with long-term chronic stroke: a pilot study.
Topics: Aged; Anesthetics, Local; Bupivacaine; Chronic Disease; Chronic Pain; Female; Functional Laterality; | 2017 |
Multimodal intrathecal analgesia in refractory cancer pain.
Topics: Aged; Analgesics; Bupivacaine; Cancer Pain; Chronic Pain; Clonidine; Female; Follow-Up Studies; Huma | 2017 |
Combined Superficial and Deep Serratus Plane Block With Bupivacaine, Dexamethasone, and Clonidine in the Treatment of a Patient With Postmastectomy Pain Syndrome: A Case Report.
Topics: Adult; Analgesics; Anesthetics; Bupivacaine; Chronic Pain; Clonidine; Dexamethasone; Drug Therapy, C | 2018 |
Retrograde placement of an intrathecal catheter for chronic low pelvic cancer pain.
Topics: Bupivacaine; Cancer Pain; Catheterization; Chronic Pain; Colonic Neoplasms; Fluoroscopy; Humans; Hyd | 2019 |
Oral Gabapentinoids and Nerve Blocks for the Treatment of Chronic Ocular Pain.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics; Anesthetics, Local; Bupivacaine; C | 2020 |
Repeated Intercostal Nerve Blocks With Liposomal Bupivacaine for Chronic Chest Pain: A Case Report.
Topics: Bupivacaine; Chest Pain; Chronic Pain; Female; Humans; Injections; Intercostal Nerves; Liposomes; Ne | 2019 |
When will we get a new class of analgesic agent based on animal study data?
Topics: Acute Pain; Bupivacaine; Chronic Pain; Humans; Ketorolac | 2014 |
Analgesic Effect of Intra-Articular Injection of Temperature-Responsive Hydrogel Containing Bupivacaine on Osteoarthritic Pain in Rats.
Topics: Analgesics; Anesthetics, Local; Animals; Arthralgia; Behavior, Animal; Bupivacaine; Chronic Pain; Di | 2015 |
Combination of intrathecal opioids with bupivacaine attenuates opioid dose escalation in chronic noncancer pain patients.
Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Chronic Pain; Clinical Trials as Topic; D | 2011 |
Fatal complication after endoscopic ultrasound-guided celiac plexus neurolysis.
Topics: Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Chronic Pain; Endosonography; Ethanol; Fatal Outc | 2012 |
Ultrasound-guided ilioinguinal/iliohypogastric nerve blocks for chronic pain after inguinal hernia repair.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anti-Inflammatory Agents; Bupivacaine; Chronic Pain; Ele | 2013 |