bupivacaine has been researched along with Obesity in 17 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "75% bupivacaine must frequently be augmented to provide adequate analgesia for cesarean section in thin parturients (BMI below 28) whereas it is too high a dosage for obese patients." | 5.26 | Obesity and the cephalad spread of analgesia following epidural administration of bupivacaine for Cesarean section. ( Hodgkinson, R; Husain, FJ, 1980) |
| "Obesity has been associated with chronic pain following TJA." | 1.48 | The Effects of Body Mass Index on Pain Control With Liposomal Bupivacaine in Hip and Knee Arthroplasty. ( Campbell, AL; Iorio, R; Karia, R; Stuchin, SA; Yu, S, 2018) |
| " Mean dosage of 0." | 1.46 | [Epidural analgesia in 20 parturients at the Sylvanus Olympio University Hospital Center in Lomé (Togo)]. ( Akala-Yoba, G; Assénouwé, S; Egbohou, P; Mouzou, T; Sama, HD; Tchétike, P; Tomta, K, 2017) |
| "Obesity has a significant effect on the cephalic spread of a spinal block (SB) due to a reduction in cerebrospinal fluid (CSF)." | 1.42 | The Levels and Duration of Sensory and Motor Blockades of Spinal Anesthesia in Obese Patients That Underwent Urological Operations in the Lithotomy Position. ( Ciftci, T; Daskaya, H; İnal, V; Kepekci, AB; Yavasca, HP, 2015) |
| " Further studies are necessary to confirm these findings in order to determine adequate local anaesthetic dosing for thoracic epidural analgesia in obese patients." | 1.39 | Postoperative epidural analgesia in obese patients undergoing liver resection surgery. ( Bellamy, M; Biercamp, C; Hudson-Phillips, S; Kocarev, M; Milan, Z; Pane, H; Procter, H; Rajasekar, N; Simpson, R, 2013) |
| "Local anesthetic inguinal hernia repair in the obese is safe and well tolerated." | 1.35 | Local anesthetic hernia repair in overweight and obese patients. ( Reid, TD; Sanjay, P; Woodward, A, 2009) |
| "1% w/v bupivacaine (20 mg), with a dosing increment of 0." | 1.33 | Obese parturients have lower epidural local anaesthetic requirements for analgesia in labour. ( Columb, MO; Panni, MK, 2006) |
| "75% bupivacaine must frequently be augmented to provide adequate analgesia for cesarean section in thin parturients (BMI below 28) whereas it is too high a dosage for obese patients." | 1.26 | Obesity and the cephalad spread of analgesia following epidural administration of bupivacaine for Cesarean section. ( Hodgkinson, R; Husain, FJ, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (17.65) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Egbohou, P | 1 |
| Mouzou, T | 1 |
| Sama, HD | 1 |
| Tchétike, P | 1 |
| Assénouwé, S | 1 |
| Akala-Yoba, G | 1 |
| Tomta, K | 1 |
| Campbell, AL | 1 |
| Yu, S | 1 |
| Karia, R | 1 |
| Iorio, R | 1 |
| Stuchin, SA | 1 |
| Araco, A | 2 |
| Araco, F | 2 |
| Gravante, G | 2 |
| Ciftci, T | 1 |
| Kepekci, AB | 1 |
| Yavasca, HP | 1 |
| Daskaya, H | 1 |
| İnal, V | 1 |
| Ngaka, TC | 1 |
| Coetzee, JF | 1 |
| Dyer, RA | 1 |
| Reid, TD | 1 |
| Sanjay, P | 1 |
| Woodward, A | 1 |
| Pooney, J | 1 |
| Kim, WH | 1 |
| Lee, JH | 1 |
| Ko, JS | 1 |
| Ahn, HJ | 1 |
| Park, SK | 1 |
| Gwak, MS | 1 |
| Kim, GS | 1 |
| Milan, Z | 1 |
| Rajasekar, N | 1 |
| Hudson-Phillips, S | 1 |
| Pane, H | 1 |
| Procter, H | 1 |
| Simpson, R | 1 |
| Kocarev, M | 1 |
| Biercamp, C | 1 |
| Bellamy, M | 1 |
| Lim, Y | 1 |
| Loo, CC | 1 |
| Goh, E | 1 |
| Panni, MK | 1 |
| Columb, MO | 1 |
| Varela, C | 1 |
| Palacio, F | 1 |
| Reina, MA | 1 |
| López, A | 1 |
| Benito-León, J | 1 |
| Rucci, FS | 1 |
| Migliori, P | 1 |
| Lisi, A | 1 |
| Cardamone, M | 1 |
| Hodgkinson, R | 1 |
| Husain, FJ | 1 |
| Toyota, K | 1 |
| Sakura, S | 1 |
| Fukuda, N | 1 |
| Saito, Y | 1 |
| Taivainen, T | 1 |
| Tuominen, M | 1 |
| Rosenberg, PH | 1 |
| McCulloch, WJ | 1 |
| Littlewood, DG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness of Subarachnoid Hyperbaric Bupivacaine on Mean Arterial Blood Pressure in Pregnant Patients With Obesity Operated by Cesarean Section[NCT04205344] | Phase 4 | 40 participants (Actual) | Interventional | 2017-02-01 | Completed | ||
| Effect of Subarachnoid Hyperbaric Bupivacaine on Mean Arterial Pressure in Obese Pregnant Patients Undergoing Cesarean Section[NCT06060015] | Phase 4 | 106 participants (Anticipated) | Interventional | 2023-08-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for bupivacaine and Obesity
| Article | Year |
|---|---|
The effect of body mass index on spinal anaesthesia for total knee replacement arthroplasty: a dose-response study.
Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Arthroplasty, Replacement, Knee; Body Mass Index; Bupi | 2012 |
Influence of obesity on the spread of spinal analgesia after injection of plain 0.5% bupivacaine at the L3-4 or L4-5 interspace.
Topics: Adult; Anesthesia, Spinal; Bupivacaine; Female; Humans; Male; Middle Aged; Motor Neurons; Neurons, A | 1990 |
15 other studies available for bupivacaine and Obesity
| Article | Year |
|---|---|
[Epidural analgesia in 20 parturients at the Sylvanus Olympio University Hospital Center in Lomé (Togo)].
Topics: Adult; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Cesarean Sec | 2017 |
The Effects of Body Mass Index on Pain Control With Liposomal Bupivacaine in Hip and Knee Arthroplasty.
Topics: Adult; Aged; Anesthetics, Local; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bo | 2018 |
The transversus abdominis plane block after postbariatric abdominoplasty: reasons for pitfalls.
Topics: Abdominal Muscles; Abdominoplasty; Adult; Analgesics; Anesthetics, Local; Bariatric Surgery; Bupivac | 2013 |
The Levels and Duration of Sensory and Motor Blockades of Spinal Anesthesia in Obese Patients That Underwent Urological Operations in the Lithotomy Position.
Topics: Aged; Anesthesia, Spinal; Bupivacaine; Hemodynamics; Humans; Male; Middle Aged; Obesity; Supine Posi | 2015 |
The Influence of Body Mass Index on Sensorimotor Block and Vasopressor Requirement During Spinal Anesthesia for Elective Cesarean Delivery.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Body Mas | 2016 |
The Influence of Body Mass Index on Sensorimotor Block and Vasopressor Requirement During Spinal Anesthesia for Elective Cesarean Delivery.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Body Mas | 2016 |
The Influence of Body Mass Index on Sensorimotor Block and Vasopressor Requirement During Spinal Anesthesia for Elective Cesarean Delivery.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Body Mas | 2016 |
The Influence of Body Mass Index on Sensorimotor Block and Vasopressor Requirement During Spinal Anesthesia for Elective Cesarean Delivery.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Body Mas | 2016 |
Local anesthetic hernia repair in overweight and obese patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Body Mass Index; | 2009 |
Transversus abdominis plane block reduces the analgesic requirements after abdominoplasty with flank liposuction.
Topics: Abdominal Fat; Abdominal Muscles; Adult; Analysis of Variance; Body Mass Index; Bupivacaine; Case-Co | 2010 |
Postoperative epidural analgesia in obese patients undergoing liver resection surgery.
Topics: Aged; Analgesia, Epidural; Anesthesia, General; Anesthetics; Body Mass Index; Bupivacaine; Drug Ther | 2013 |
Ultra low dose combined spinal and epidural anesthesia for cesarean section.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Ane | 2004 |
Obese parturients have lower epidural local anaesthetic requirements for analgesia in labour.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Anthropometry; Body Mass Ind | 2006 |
[Horner's syndrome secondary to epidural anesthesia].
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Arm; Bupivacaine; Cesarean | 2007 |
[Clinico-statistical study on various factors that could influence the area of analgesia in lumbar epidural block].
Topics: Adolescent; Adult; Aged; Anesthesia, Epidural; Anesthetics; Body Height; Body Weight; Bupivacaine; F | 1984 |
Obesity and the cephalad spread of analgesia following epidural administration of bupivacaine for Cesarean section.
Topics: Adult; Age Factors; Analgesia; Anesthesia, Epidural; Anesthesia, Obstetrical; Body Height; Body Weig | 1980 |
[Epidural anesthesia and general anesthesia using the cuffed oropharyngeal airway for an obese patient with Duchenne's muscular dystrophy].
Topics: Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Local; Breast Neoplasms | 1999 |
Influence of obesity on spinal analgesia with isobaric 0.5% bupivacaine.
Topics: Aged; Anesthesia, Spinal; Bupivacaine; Humans; Male; Middle Aged; Obesity; Specific Gravity | 1986 |