Compounds > bupivacaine
Page last updated: 2024-10-24

bupivacaine and Neuromuscular Blockade

bupivacaine has been researched along with Neuromuscular Blockade in 25 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Neuromuscular Blockade: The intentional interruption of transmission at the NEUROMUSCULAR JUNCTION by external agents, usually neuromuscular blocking agents. It is distinguished from NERVE BLOCK in which nerve conduction (NEURAL CONDUCTION) is interrupted rather than neuromuscular transmission. Neuromuscular blockade is commonly used to produce MUSCLE RELAXATION as an adjunct to anesthesia during surgery and other medical procedures. It is also often used as an experimental manipulation in basic research. It is not strictly speaking anesthesia but is grouped here with anesthetic techniques. The failure of neuromuscular transmission as a result of pathological processes is not included here.

Research Excerpts

ExcerptRelevanceReference
"2 mg x kg(-1) x h(-1)) postoperative epidural infusions of bupivacaine (Group B; n = 28), levobupivacaine (Group L; n = 27), and ropivacaine (Group R; n = 26) in children after hypospadias repair."5.11A comparison of epidural bupivacaine, levobupivacaine, and ropivacaine on postoperative analgesia and motor blockade. ( De Negri, P; Eksborg, S; Ivani, G; Lonnqvist, PA; Modano, P; Reato, C; Tirri, T, 2004)
"Demography, upper sensory block, visual analog scale scores at rest and after coughing, levobupivacaine and rescue morphine consumption, motor blockade, hemodynamics, postoperative nausea and vomiting, sedation, and patient satisfaction were recorded within the first 48 hours."5.11Comparison of 2 concentrations of levobupivacaine in postoperative patient-controlled epidural analgesia. ( Bardiau, F; Boogaerts, JG; Dernedde, M; Stadler, M, 2005)
"To evaluate the effects of levobupivacaine on neuromuscular transmission and neuromuscular blockade produced by pancuronium in vitro."3.83Association between levobupivacaine and pancuronium. Interference in neuromuscular transmission and blockade in rats. ( Braga, Ade F; Braga, FS; Carvalho, VH; Junqueira, FE; Potério, GM; Santos, FN, 2016)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (16.00)18.2507
2000's11 (44.00)29.6817
2010's10 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bayley, KD1
Read, RA1
Ituk, US1
McCoy, DM1
Carvalho, VH1
Braga, Ade F1
Braga, FS1
Potério, GM1
Santos, FN1
Junqueira, FE1
Eppstein, AC1
Sakamoto, B1
Kumar, N1
Sardana, R1
Kaur, R1
Jain, A1
Demiraran, Y1
Yucel, I1
Akcali, GE1
Degirmenci, E1
Sezen, G1
Iskender, A1
Araco, A1
Pooney, J1
Araco, F1
Gravante, G1
Gill, VS1
Presland, AH1
Lord, JA1
Bunce, C1
Xing, W1
Charteris, DG1
Sahin, SH1
Colak, A1
Sezer, A1
Arar, C1
Sevdi, S1
Gunday, I1
Sut, N1
Mahdy, RA1
Ghanem, MT1
Riad, W1
Ahmad, N1
Kumar, CM1
De Negri, P2
Ivani, G2
Tirri, T1
Modano, P1
Reato, C1
Eksborg, S1
Lonnqvist, PA2
Evron, S1
Glezerman, M1
Sadan, O1
Boaz, M1
Ezri, T1
L'Erario, M1
Mossetti, V1
Difilippo, A1
Rosso, F1
Dernedde, M1
Stadler, M1
Bardiau, F1
Boogaerts, JG1
Girard, T1
Kern, C1
Hösli, I1
Heck, A1
Schneider, MC1
Atallah, MM1
Shorrab, AA1
Abdel Mageed, YM1
Demian, AD1
Schultz, AM1
Werba, A1
Ulbing, S1
Gollmann, G1
Lehofer, F1
Crowhurst, JA1
Guise, P1
Laurent, S1
Mann, C1
Pouzeratte, Y1
Boccara, G1
Peccoux, C1
Vergne, C1
Brunat, G1
Domergue, J1
Millat, B1
Colson, P1
Kooger Infante, NE1
Van Gessel, E1
Forster, A1
Gamulin, Z1
Sharma, T1
Gopal, L1
Parikh, S1
Shanmugam, MP1
Saha, SK1
Sulochana, KR1
Shetty, NS1
Mukesh, BN1
Badrinath, SS1
López-Soriano, F1
Lajarín, B1
Rivas, F1
Verdú, JM1
López-Robles, J1
Uy, HS1
de Jesus, AA1
Paray, AA1
Flores, JD1
Felizar, LB1

Trials

18 trials available for bupivacaine and Neuromuscular Blockade

ArticleYear
Sub-Tenon's anesthesia for canine cataract surgery.
    Veterinary ophthalmology, 2018, Volume: 21, Issue:6

    Topics: Anesthesia, Conduction; Animals; Bupivacaine; Cataract; Dog Diseases; Dogs; Female; Intraocular Pres

2018
Adding intrathecal morphine to unilateral spinal anesthesia results in better pain relief following knee arthroscopy.
    Journal of anesthesia, 2008, Volume: 22, Issue:4

    Topics: Aged; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Arthroscopy; Bupivacaine; Double-B

2008
Two-quadrant high-volume sub-Tenon's anaesthesia for vitrectomy: a randomised controlled trial.
    The British journal of ophthalmology, 2012, Volume: 96, Issue:2

    Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Female; Humans; Hya

2012
Effect of epidural levobupivacaine on recovery from vecuronium-induced neuromuscular block in patients undergoing lower abdominal surgery.
    Anaesthesia and intensive care, 2011, Volume: 39, Issue:4

    Topics: Abdomen; Adult; Aged; Anesthesia Recovery Period; Anesthesia, Epidural; Anesthesia, General; Anesthe

2011
Comparison between single-injection inferomedial and inferotemporal peribulbar blockades before cataract surgery.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2012, Volume: 227, Issue:2

    Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Cataract Extraction

2012
Comparison of metal and flexible sub-Tenon cannulas.
    Journal of cataract and refractive surgery, 2012, Volume: 38, Issue:8

    Topics: Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Catheters; Double-Blind M

2012
A comparison of epidural bupivacaine, levobupivacaine, and ropivacaine on postoperative analgesia and motor blockade.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:1

    Topics: Amides; Analgesia, Epidural; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Dose-Response

2004
Patient-controlled epidural analgesia for labor pain: effect on labor, delivery and neonatal outcome of 0.125% bupivacaine vs 0.2% ropivacaine.
    International journal of obstetric anesthesia, 2004, Volume: 13, Issue:1

    Topics: Adult; Amides; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Anestheti

2004
Caudal anesthesia for minor pediatric surgery: a prospective randomized comparison of ropivacaine 0.2% vs levobupivacaine 0.2%.
    Paediatric anaesthesia, 2005, Volume: 15, Issue:6

    Topics: Amides; Anesthesia, Caudal; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Double-Blind M

2005
Comparison of 2 concentrations of levobupivacaine in postoperative patient-controlled epidural analgesia.
    Journal of clinical anesthesia, 2005, Volume: 17, Issue:7

    Topics: Abdomen; Adolescent; Adult; Aged; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Op

2005
Ropivacaine versus bupivacaine 0.125% with fentanyl 1 microg/ml for epidural labour analgesia: is daily practice more important than pharmaceutical choice?
    Acta anaesthesiologica Belgica, 2006, Volume: 57, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Amides; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Lo

2006
Low-dose bupivacaine spinal anaesthesia for percutaneous nephrolithotomy: the suitability and impact of adding intrathecal fentanyl.
    Acta anaesthesiologica Scandinavica, 2006, Volume: 50, Issue:7

    Topics: Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine;

2006
Peri-operative thoracic epidural analgesia for thoracotomy.
    European journal of anaesthesiology, 1997, Volume: 14, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Female; Fenta

1997
Sub-Tenon's block: the effect of hyaluronidase on speed of onset and block quality.
    Anaesthesia and intensive care, 1999, Volume: 27, Issue:2

    Topics: Aged; Anesthetics, Local; Bupivacaine; Cataract Extraction; Double-Blind Method; Female; Humans; Hya

1999
Comparison of intravenous or epidural patient-controlled analgesia in the elderly after major abdominal surgery.
    Anesthesiology, 2000, Volume: 92, Issue:2

    Topics: Abdomen; Aged; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics,

2000
Extent of hyperbaric spinal anesthesia influences the duration of spinal block.
    Anesthesiology, 2000, Volume: 92, Issue:5

    Topics: Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Female; Hemodynamics; Humans; Hyperbaric Oxygen

2000
[Hyperbaric subarachnoid ropivacaine in ambulatory surgery: comparative study with hyperbaric bupivacaine].
    Revista espanola de anestesiologia y reanimacion, 2002, Volume: 49, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Amides; Anesthesia Recov

2002
Ropivacaine-lidocaine versus bupivacaine-lidocaine for retrobulbar anesthesia in cataract surgery.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amides; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local

2002

Other Studies

7 other studies available for bupivacaine and Neuromuscular Blockade

ArticleYear
Catecholamine-induced cardiomyopathy: a complication following a retrobulbar block.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2014, Volume: 49, Issue:2

    Topics: Anesthetics, Local; Bupivacaine; Cardiomyopathies; Cardiotonic Agents; Continuous Positive Airway Pr

2014
Association between levobupivacaine and pancuronium. Interference in neuromuscular transmission and blockade in rats.
    Acta cirurgica brasileira, 2016, Volume: 31, Issue:7

    Topics: Anesthetics, Local; Animals; Bupivacaine; Diaphragm; Drug Therapy, Combination; Electric Stimulation

2016
The novel use of different bupivacaine preparations with combined regional techniques for postoperative pain management in non-opioid-based laparoscopic inguinal herniorrhaphy.
    Journal of clinical anesthesia, 2016, Volume: 34

    Topics: Analgesics, Non-Narcotic; Anesthesia, General; Anesthesia, Local; Anesthesia, Spinal; Anesthetics, L

2016
Intraoperative mandibular nerve block with peripheral nerve stimulator for temporomandibular joint ankylosis.
    Journal of clinical anesthesia, 2016, Volume: 35

    Topics: Androstanols; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, L

2016
Transversus abdominis plane block reduces the analgesic requirements after abdominoplasty with flank liposuction.
    Annals of plastic surgery, 2010, Volume: 65, Issue:4

    Topics: Abdominal Fat; Abdominal Muscles; Adult; Analysis of Variance; Body Mass Index; Bupivacaine; Case-Co

2010
Ropivacaine 0.5% and bupivacaine 0.5% epidural blockade for lower limb orthopaedic surgery.
    Anaesthesia and intensive care, 1998, Volume: 26, Issue:4

    Topics: Amides; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Humans; Leg; Neuromuscular Blockade;

1998
pH-adjusted periocular anaesthesia for primary vitreoretinal surgery.
    Indian journal of ophthalmology, 1999, Volume: 47, Issue:4

    Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Drug Combinations; Female; Humans;

1999