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bupivacaine and Neurogenic Inflammation

bupivacaine has been researched along with Neurogenic Inflammation in 4 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Neurogenic Inflammation: Inflammation caused by an injurious stimulus of peripheral neurons and resulting in release of neuropeptides which affect vascular permeability and help initiate proinflammatory and immune reactions at the site of injury.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to evaluate the effect of local anesthetic blockade of afferent innervation on the development of capsaicin-induced edema in the rat temporomandibular joint (TMJ) region and on reflex jaw muscle activity."3.72Capsaicin-induced joint inflammation is not blocked by local anesthesia. ( Haas, DA; Hu, JW; Tang, ML, 2004)
"Tetrodotoxin was less efficacious for inhibiting the TNF-alpha transport and the rise in receptor expression and for inhibiting the axonal transport ex vivo."1.36Effects of a bupivacaine nerve block on the axonal transport of Tumor Necrosis Factor-alpha (TNF-alpha) in a rat model of carrageenan-induced inflammation. ( Beloeil, H; Benhamou, D; Combettes, E; Deruddre, S; Duranteau, J; Estebe, JP; Mazoit, JX, 2010)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, S1
Jo, S1
Talbot, S1
Zhang, HB1
Kotoda, M1
Andrews, NA1
Puopolo, M1
Liu, PW1
Jacquemont, T1
Pascal, M1
Heckman, LM1
Jain, A1
Lee, J1
Woolf, CJ1
Bean, BP1
Deruddre, S1
Combettes, E1
Estebe, JP1
Duranteau, J1
Benhamou, D1
Beloeil, H1
Mazoit, JX2
Tang, ML1
Haas, DA1
Hu, JW1
Gentili, ME1
Samii K, K1
Fletcher, D1

Other Studies

4 other studies available for bupivacaine and Neurogenic Inflammation

ArticleYear
Novel charged sodium and calcium channel inhibitor active against neurogenic inflammation.
    eLife, 2019, 11-25, Volume: 8

    Topics: Animals; Bupivacaine; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Signaling

2019
Effects of a bupivacaine nerve block on the axonal transport of Tumor Necrosis Factor-alpha (TNF-alpha) in a rat model of carrageenan-induced inflammation.
    Brain, behavior, and immunity, 2010, Volume: 24, Issue:4

    Topics: Anesthetics, Local; Animals; Axonal Transport; Bupivacaine; Carrageenan; Disease Models, Animal; Ede

2010
Capsaicin-induced joint inflammation is not blocked by local anesthesia.
    Anesthesia progress, 2004, Volume: 51, Issue:1

    Topics: Analysis of Variance; Anesthetics, Local; Animals; Bupivacaine; Capsaicin; Dose-Response Relationshi

2004
The effect of a sciatic nerve block on the development of inflammation in carrageenan injected rats.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:4

    Topics: Anesthetics, Local; Animals; Body Temperature; Bupivacaine; Carrageenan; Edema; Epinephrine; Excipie

1999