Page last updated: 2024-10-24

bupivacaine and Nausea

bupivacaine has been researched along with Nausea in 86 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.

Research Excerpts

ExcerptRelevanceReference
"25% bupivacaine with 1/200,000 epinephrine on the ease of surgery and its effect on post-operative pain and nausea."9.14The effect of peri-stomal infiltration with bupivacaine/epinephrine on post-operative pain, nausea and ease of surgery in reversal of loop ileostomies. ( Clough, D; Macdonald, A; McCaffer, L; Muir, V; Shalli, K; Watson, C, 2009)
"To determine whether postoperative pain and nausea after laparoscopic sterilization can be reduced with a combination of bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning."9.08Reduction of pain and nausea after laparoscopic sterilization with bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning. ( Bradford, TH; Meeks, GR; Norman, PF; Robertson, K, 1995)
"Postoperative nausea and vomiting (PONV) following major arthroplasty with spinal anaesthesia and intrathecal morphine is reported in 45-74% of patients."9.08Nausea and vomiting after major arthroplasty with spinal anaesthesia including morphine: a randomised trial of subhypnotic propofol infusion as prophylaxis. ( Grattidge, P, 1998)
"We have studied the effect of tropisetron, a 5-HT3-receptor antagonist, on postoperative nausea, vomiting and pain in 54 patients, aged 50-83 yr, after major hip or knee surgery."9.07Effect of tropisetron, a 5-HT3 receptor antagonist, on analgesia and nausea after intrathecal morphine. ( Niemi, L; Pitkänen, MT; Rosenberg, PH; Tuominen, MK, 1993)
"A prospective double-masked clinical trial was conducted to determine whether retrobulbar bupivacaine block had an effect on post-operative pain, nausea and intra- and post-operative use of analgesics in retinal detachment surgery performed under general anaesthesia."9.07Effects of retrobulbar bupivacaine on post-operative pain and nausea in retinal detachment surgery. ( Gíslason, I; Gottfreothsdóttir, MS; Nielsen, NC; Sigurjónsdóttir, S; Stefánsson, E, 1993)
"Itching was less in both of the higher dose naloxone groups (P<0."6.69Epidural naloxone reduces pruritus and nausea without affecting analgesia by epidural morphine in bupivacaine. ( Bishop, MJ; Choi, JH; Lee, J, 2000)
"Postoperative pain was reduced significantly (P < 0."6.68A double-blinded evaluation of intraperitoneal bupivacaine vs saline for the reduction of postoperative pain and nausea after laparoscopic cholecystectomy. ( Barie, PS; Hydo, L; Szem, JW, 1996)
" Intrathecal morphine prolongs analgesia after surgery, but has been implicated in nausea and vomiting, pruritus, postoperative respiratory depression, or apneic episodes."5.51Comparison of low-dose morphine intrathecal analgesia and sufentanil PCIA in elderly patients with hip fracture undergoing single spinal anesthesia - a randomized clinical trial. ( Guo, K; Jin, F; Liang, D; Liu, Y; Tang, Z; Xu, Z; Yang, X; Yao, J, 2022)
" Nausea and vomiting occurred more frequently with higher doses of meperidine (P < 0."5.15Antishivering effects of two different doses of intrathecal meperidine in caesarean section: a prospective randomised blinded study. ( Khan, ZH; Makarem, J; Samadi, S; Zanjani, AP, 2011)
" The incidences of maternal hypotension and nausea and vomiting were similar among groups, although the ephedrine requirements were significantly increased in the isobaric and hypobaric groups by factors of 1."5.15Does the baricity of bupivacaine influence intrathecal spread in the prolonged sitting position before elective cesarean delivery? A prospective randomized controlled study. ( Columb, M; Fernando, R; Hallworth, S; Loubert, C; Patel, N; Sarang, K; Sodhi, V, 2011)
"25% bupivacaine with 1/200,000 epinephrine on the ease of surgery and its effect on post-operative pain and nausea."5.14The effect of peri-stomal infiltration with bupivacaine/epinephrine on post-operative pain, nausea and ease of surgery in reversal of loop ileostomies. ( Clough, D; Macdonald, A; McCaffer, L; Muir, V; Shalli, K; Watson, C, 2009)
"At all recorded intervals, the average degree of nausea was greater in the sodium citrate group compared to the famotidine group."5.12Oral sodium citrate increases nausea amongst elective Cesarean delivery patients. ( Abramovitz, S; Comerford, M; DiMaria, L; Gadalla, F; Kiselev, M; Kjaer, K; Kondilis, L; Leighton, BL; Samuels, J, 2006)
"The addition of small dose of morphine to the spinal component of the CSE technique improved the effectiveness of epidural labour analgesia and reduced the need for pain medications over 24 h, but resulted in a small increase in nausea."5.12Intrathecal morphine reduces breakthrough pain during labour epidural analgesia. ( Hess, PE; Sarge, TW; Snowman, CE; Sundar, S; Vasudevan, A, 2007)
"Rapid intrathecal injection of hyperbaric bupivacaine does not affect spread of spinal anesthesia or the incidence of hypotension and nausea in parturients."5.12Influence of injection rate of hyperbaric bupivacaine on spinal block in parturients: a randomized trial. ( Butler, R; Morley-Forster, PK; Shamsah, M; Singh, SI, 2007)
"The use of intrathecal neostigmine as an analgesic drug in perianal surgery is unsatisfactory because of prolonged motor blockade and nausea."5.10Analgesic effects of intrathecal neostigmine in perianal surgery. ( Erman, M; Karsli, B; Yegin, A; Yilmaz, M, 2003)
"5 mg bupivacaine given intrathecally via combined spinal epidural (CSE) for labour pain relief in the first stage."5.09Combined spinal epidural for labour analgesia--duration, efficacy and side effects of adding sufentanil or fentanyl to bupivacaine intrathecally vs plain bupivacaine. ( Chen, LH; Chong, JL; Lo, WK, 1999)
" We recorded pain as assessed on a visual analog scale, extension of sensory and motor block, maternal hemodynamic constants, number of boluses of bupivacaine used, total doses of bupivacaine and oxytocin, instruments needed for childbirth, and side effects (pruritus, nausea and vomiting)."5.09[The efficacy and safety of continuous epidural analgesia versus intradural-epidural analgesia during labor]. ( Caba, F; Calderón, J; Echevarría, M; Gómez, P; Martínez, A; Rodríguez, R, 2001)
"To determine whether postoperative pain and nausea after laparoscopic sterilization can be reduced with a combination of bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning."5.08Reduction of pain and nausea after laparoscopic sterilization with bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning. ( Bradford, TH; Meeks, GR; Norman, PF; Robertson, K, 1995)
"Use of hyperbaric bupivacaine offers advantages over the other techniques, as it assures more consistent attainment of metameric level, an incidence of visceral pain that is lower than that of isobaric mepivacaine, and fewer hemodynamic repercussions than isobaric bupivacaine with vasoconstrictor."5.08[Effect of the local anesthetic on visceral pain in cesarean sections done under intradural anesthesia]. ( Bernal, L; Caba, F; Echevarría, M; Pallarés, JA; Rodríguez, R, 1996)
"We aimed to determine the usefulness of intrathecal pethidine as the sole anaesthetic for transurethral resection of prostate (TURP) while comparing the incidence of hypotension with intrathecal bupivacaine."5.08Intrathecal pethidine: an alternative anaesthetic for transurethral resection of prostate? ( Chong, JL; Chow, MY; Koay, CK; Sia, AT, 1997)
"Postoperative nausea and vomiting (PONV) following major arthroplasty with spinal anaesthesia and intrathecal morphine is reported in 45-74% of patients."5.08Nausea and vomiting after major arthroplasty with spinal anaesthesia including morphine: a randomised trial of subhypnotic propofol infusion as prophylaxis. ( Grattidge, P, 1998)
" morphine 100 microg, but with a high incidence of nausea and vomiting."5.08The efficacy of intrathecal neostigmine, intrathecal morphine, and their combination for post-cesarean section analgesia. ( Chin, YJ; Chung, CJ; Kim, JS; Park, HS, 1998)
"A prospective double-masked clinical trial was conducted to determine whether retrobulbar bupivacaine block had an effect on post-operative pain, nausea and intra- and post-operative use of analgesics in retinal detachment surgery performed under general anaesthesia."5.07Effects of retrobulbar bupivacaine on post-operative pain and nausea in retinal detachment surgery. ( Gíslason, I; Gottfreothsdóttir, MS; Nielsen, NC; Sigurjónsdóttir, S; Stefánsson, E, 1993)
"We have studied the effect of tropisetron, a 5-HT3-receptor antagonist, on postoperative nausea, vomiting and pain in 54 patients, aged 50-83 yr, after major hip or knee surgery."5.07Effect of tropisetron, a 5-HT3 receptor antagonist, on analgesia and nausea after intrathecal morphine. ( Niemi, L; Pitkänen, MT; Rosenberg, PH; Tuominen, MK, 1993)
" For management of postoperative muscle spasm, an intravenous benzodiazepine was used (diazepam 0."3.69Pain management for children following selective dorsal rhizotomy. ( Geiduschek, JM; Haberkern, CM; Hays, RM; Jacobson, LE; McLaughlin, JF; Roberts, TS, 1994)
"TQLB and PCI do not improve postoperative pain scores or total opioid consumption compared to PCI alone."3.30Transmuscular Quadratus Lumborum Block Does Not Provide Significant Benefit for Primary Hip Arthroscopy with Pericapsular Infiltration: A Randomized Control Trial. ( Commeh, E; Cuff, G; Diskina, D; Hertling, A; Kaplan, DJ; Umeh, UO; Youm, T, 2023)
"There were no episodes of laryngospasm in the group 3 in comparison with the other groups."3.11Addition of magnesium sulfate to bupivacaine improves analgesic efficacy after tonsillectomy: A randomized trial and a CONSORT analysis. ( Achour, I; Chakroun, A; Charfeddine, I; Derbel, R; Thabet, W; Zouch, I, 2022)
"Patients undergoing QL block had lower postoperative pain scores without the undesirable side effects of opioids such as nausea, vomiting, and pruritus."3.11Randomized Clinical Trial Comparing Quadratus Lumborum Block and Intrathecal Morphine for Postcesarean Analgesia. ( Araújo, KM; Ferraro, LHC; Mattar, R; Sun, SY, 2022)
"Postoperative pain was significantly less in the bupivacaine group at 240 and 360 min after the surgery."3.11Comparing the efficacy of peritonsillar injection of bupivacaine and intravenous acetaminophen on post-tonsillectomy pain in children. ( Ayatollahi, V; Hosseini, H; Meybodian, M; Shariatmadari, M; Vaziribozorg, S, 2022)
" There were no differences in other adverse events such as urinary retention, sedation, and motor block among the three groups."2.71Efficacy and adverse effects of patient-controlled epidural or intravenous analgesia after major surgery. ( Hu, JS; Liew, C; Lui, PW; Teng, YH; Tsai, SK, 2004)
" In this study, we compared the efficacy, dose requirements, side effects, and motor block observed with epidural levobupivacaine and ropivacaine when given in combination with small-dose morphine for 60 h after major abdominal surgery."2.71Epidural levobupivacaine 0.1% or ropivacaine 0.1% combined with morphine provides comparable analgesia after abdominal surgery. ( Geortay, MN; Honoré, PD; Jacquemin, MJ; Joris, JL; Kaba, A; Lamy, ML; Maquoi, LM; Senard, M, 2004)
"Itching was less in both of the higher dose naloxone groups (P<0."2.69Epidural naloxone reduces pruritus and nausea without affecting analgesia by epidural morphine in bupivacaine. ( Bishop, MJ; Choi, JH; Lee, J, 2000)
"Postoperative pain was reduced significantly (P < 0."2.68A double-blinded evaluation of intraperitoneal bupivacaine vs saline for the reduction of postoperative pain and nausea after laparoscopic cholecystectomy. ( Barie, PS; Hydo, L; Szem, JW, 1996)
"Nausea was noted in 61% of the parturients in the lateral group and in 22% (P < 0."2.67Posture and the spread of hyperbaric bupivacaine in parturients using the combined spinal epidural technique. ( Morgan, B; Patel, M; Samsoon, G; Swami, A, 1993)
"Postoperative pain was scored with Hannalah and Broadman's score (0 to 10) 2, 4, 8 and 24 h after the caudal block."2.67[Caudal block in children: analgesia and respiratory effect of the combination bupivacaine-fentanyl]. ( Ecoffey, C; Moine, P, 1992)
" There were significant differences between the two groups in pain score, patient assessment of analgesia quality, time to first analgesic intervention, and total dosage of hydromorphone during the first 24 hours."2.66Epidural hydromorphone for postcesarean analgesia. ( Chestnut, DH; Choi, WW; Isbell, TJ, 1986)
"We present a case of retrobulbar hemorrhage complicating sub-Tenon's anesthesia in a patient receiving oral anticoagulants."1.34Retrobulbar hemorrhage after sub-Tenon's anesthesia. ( Best, RM; McGimpsey, S; Subbiah, S, 2007)
"We prospectively studied surgical cancer patients who received epidural bupivacaine-morphine to determine perioperative morphine use, side effects, and complications."1.29Postoperative epidural bupivacaine-morphine therapy. Experience with 4,227 surgical cancer patients. ( de Leon-Casasola, OA; Harrison, P; Lema, MJ; Massey, J; Parker, B, 1994)

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-199010 (11.63)18.7374
1990's29 (33.72)18.2507
2000's24 (27.91)29.6817
2010's14 (16.28)24.3611
2020's9 (10.47)2.80

Authors

AuthorsStudies
Hosseini, H1
Shariatmadari, M1
Ayatollahi, V1
Vaziribozorg, S2
Meybodian, M1
Choi, JW1
Lahori, A1
Merlo, JA1
Gill, O1
Ghoddoussi, F1
Patel, KM1
Desai, RG1
Hakim, J1
Zatkoff, J1
Krishnan, S1
Xu, Z1
Tang, Z1
Yao, J1
Liang, D1
Jin, F1
Liu, Y1
Guo, K1
Yang, X1
Derbel, R1
Achour, I1
Thabet, W1
Chakroun, A1
Zouch, I1
Charfeddine, I1
Araújo, KM1
Ferraro, LHC1
Sun, SY1
Mattar, R1
Umeh, UO1
Kaplan, DJ1
Diskina, D1
Commeh, E1
Cuff, G1
Hertling, A1
Youm, T1
Haque, MM1
Banik, D1
Akhtaruzzaman, AK1
Bhowmick, DK1
Kader, MA1
Reza, R1
Morshed, MM1
Hasanuzzaman, M1
Azad, AK1
Mariom, ML1
Hossain, MS1
Masud, M1
Sultana, N1
Paleti, S1
Boppanna, V1
Sobani, ZA1
McCarthy, D1
Rustagi, T1
Hatami, M1
Talebi, M1
Heiranizadeh, N1
Sahin, L1
Cesur, M1
Sahin, M1
Kilic, E1
Sen, E1
Clivatti, J1
Siddiqui, N1
Goel, A1
Shaw, M1
Crisan, I1
Carvalho, JC1
Sundarathiti, P1
Sangdee, N1
Sangasilpa, I1
Prayoonhong, W1
Papoun, S1
Maeda, A1
Shibata, SC1
Wada, H1
Marubashi, S1
Kamibayashi, T1
Eguchi, H1
Fujino, Y1
Uppal, V1
Shanthanna, H1
Prabhakar, C1
McKeen, DM1
Sakamoto, B1
Harker, G1
Eppstein, AC1
Gwirtz, K1
Khanna, A1
Saxena, R1
Dutta, A1
Ganguly, N1
Sood, J1
Kryger, ZB1
Rawlani, V1
Lu, L1
Fine, NA1
Shalli, K1
Watson, C1
McCaffer, L1
Clough, D1
Muir, V1
Macdonald, A1
Khan, ZH1
Zanjani, AP1
Makarem, J1
Samadi, S1
Loubert, C1
Hallworth, S1
Fernando, R1
Columb, M1
Patel, N1
Sarang, K1
Sodhi, V1
Xie, Z1
Hussain, W1
Cutter, TW1
Apfelbaum, JL1
Drum, ML1
Manning, DW1
Merivirta, R1
Kuusniemi, KS1
Aantaa, R1
Hurme, SA1
Aärimaa, V1
Leino, KA1
Frohlich, S1
Cooper, D1
Selvan, D1
Jagannathan, V1
Gasanova, I1
Grant, E1
Way, M1
Rosero, EB1
Joshi, GP1
Obara, M1
Sawamura, S1
Satoh, Y1
Chinzei, M1
Sekiyama, H1
Tamai, H1
Yamamoto, H1
Hanaoka, K1
Yegin, A1
Yilmaz, M1
Karsli, B1
Erman, M1
Zeng, L1
Wu, X1
Ma, Q1
Su, Y1
Poddar, RK1
Gosavi, CP1
Senard, M1
Kaba, A1
Jacquemin, MJ1
Maquoi, LM1
Geortay, MN1
Honoré, PD1
Lamy, ML1
Joris, JL1
Vernis, L1
Dualé, C1
Storme, B1
Mission, JP1
Rol, B1
Schoeffler, P1
Teng, YH1
Hu, JS1
Tsai, SK1
Liew, C1
Lui, PW1
Vicente, JM1
Guasch, EV1
Bermejo, JM1
Gilsanz, F1
Zhang, YF1
Lao, JX1
Liu, WX1
Li, Y1
Lai, GZ1
Kjaer, K1
Comerford, M1
Kondilis, L1
DiMaria, L1
Abramovitz, S1
Kiselev, M1
Samuels, J1
Gadalla, F1
Leighton, BL1
Ko, JS1
Kim, CS1
Cho, HS1
Choi, DH1
Vasudevan, A1
Snowman, CE1
Sundar, S1
Sarge, TW1
Hess, PE1
Singh, SI1
Morley-Forster, PK1
Shamsah, M1
Butler, R1
Subbiah, S1
McGimpsey, S1
Best, RM1
Ju, H1
Feng, Y1
Yang, BX1
Wang, J1
Ghosh, YK1
Van Vuuren, A1
Aggarwal, SP1
Dubash, D1
Kamal, RS1
Khan, FA1
Bradford, TH1
Robertson, K1
Norman, PF1
Meeks, GR1
Niemi, L3
Pitkänen, M2
Tuominen, M1
Rosenberg, PH3
de Leon-Casasola, OA1
Parker, B1
Lema, MJ1
Harrison, P1
Massey, J1
Geiduschek, JM1
Haberkern, CM1
McLaughlin, JF1
Jacobson, LE1
Hays, RM1
Roberts, TS1
Patel, M1
Samsoon, G1
Swami, A1
Morgan, B1
Gottfreothsdóttir, MS1
Gíslason, I1
Stefánsson, E1
Sigurjónsdóttir, S1
Nielsen, NC1
Pitkänen, MT1
Tuominen, MK1
McNicol, R1
Hirabayashi, Y1
Mitsuhata, H1
Shimizu, R1
Saitoh, J1
Saitoh, K1
Fukuda, H1
Paech, MJ1
Maberley, DA1
Kozy, DW1
Maberley, AL1
Shea, M1
Giavedoni, L1
Paolini, L1
Wong, D1
Szem, JW1
Hydo, L1
Barie, PS1
Bourke, RD1
Dowler, JG1
Heyworth, P1
Cooling, RJ1
Moore, C1
Lauretti, GR1
Azevedo, VM1
Echevarría, M2
Caba, F2
Bernal, L1
Pallarés, JA1
Rodríguez, R2
St-Onge, S1
Fugère, F1
Girard, M1
Bachmann, M1
Laakso, E1
Tsui, SL1
Lee, DK1
Ng, KF1
Chan, TY1
Chan, WS1
Lo, JW1
Milford, MA1
Paluch, TA1
Borgeat, A1
Schäppi, B1
Biasca, N1
Gerber, C1
Sia, AT1
Chow, MY1
Koay, CK1
Chong, JL2
Grattidge, P1
Chia, YY1
Liu, K1
Liu, YC1
Chang, HC1
Wong, CS1
Chung, CJ1
Kim, JS1
Park, HS1
Chin, YJ1
Rundshagen, I1
Kochs, E1
Standl, T1
Schnabel, K1
Schulte am Esch, J1
Tetzlaff, JE1
Dilger, JA1
Kodsy, M1
al-Bataineh, J1
Yoon, HJ1
Bell, GR1
Choi, JH2
Lee, J1
Bishop, MJ1
Lo, WK1
Chen, LH1
Bernard, JM1
Le Roux, D1
Barthe, A1
Jourdain, O1
Vizquel, L1
Michel, C1
Vercauteren, MP1
Van de Velde, M1
Sánchez-Conde, P1
Nicolás, J1
Rodríguez, J1
García-Castaño, M1
del Barrio, E1
Muriel, C1
Gómez, P1
Calderón, J1
Martínez, A1
Ehikhametalor, KO1
Nelson, M1
Brownridge, P1
Moine, P1
Ecoffey, C1
Chestnut, DH1
Choi, WW1
Isbell, TJ1
Lewis, RA1
Landers, MB1
Abouleish, EI1
Moore, J1
Murnaghan, GA1
Lewis, MA1
Ramaioli, F2
Pagani, I2
Panwala, NM1
Purandare, VN1
Mapelli, A1
Milne, MK1
Lawson, JI1
Brown, PR1
Arthurs, GJ1
Glashan, RW1

Clinical Trials (12)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of an Ultrasound Guided Bilateral Transversus Abdominis Plane Block With Dexamethasone and Preperitoneal Instillation of Local Anesthetic With Dexamethasone to a Standard Anesthetic Technique for Analgesic Efficacy and Patient Satisfaction Foll[NCT02036983]75 participants (Actual)Interventional2013-11-30Completed
Comparison of the Effect of Intra-articular Administration of 2% Ropivacaine vs. 7.5% Ropivacaine as an Analgesic in the Immediate Postoperative Period of Knee Arthroscopy in Acute Injuries at the ABC Medical Center[NCT05807945]Phase 468 participants (Actual)Interventional2020-04-01Completed
A Comparison of Tumescence in Breast Reduction Surgery[NCT01602692]Phase 440 participants (Actual)Interventional2012-08-31Completed
Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty[NCT05898087]Phase 4128 participants (Anticipated)Interventional2022-04-01Recruiting
Low Dose, Low Concentration Different Baricity Bupivacaine for Transuretral Prostatectomy.[NCT01861041]Phase 452 participants (Anticipated)Interventional2013-05-31Not yet recruiting
Randomized Control Trial of Ultrasound-Guided Erector Spinae Block Versus Shoulder Periarticular Anesthetic Infiltration for Pain Control After Arthroscopic Shoulder Surgery[NCT03691922]62 participants (Actual)Interventional2019-07-06Completed
Ultrasound-guided Transversus Abdominis Plane Block After Abdominal Hysterectomy: a Prospective Randomized Controlled Trial[NCT01153503]75 participants (Actual)Interventional2010-04-30Completed
Bilateral Transversus Abdominis Plane Block With or Without Magnesium for Total Abdominal Hysterectomy With or Without Salpingo-oophorectomy: a Randomized Controlled Trial[NCT02680626]Phase 486 participants (Actual)Interventional2016-01-31Terminated (stopped due to Pfannenstiel hysterectomies are now rarely performed so cannot recruit eligible patients)
Pain Control After VATS Anatomical Pulmonary Resections: Randomized Comparison Between Cryoanalgesia, Erector Spinae Plane Block and Epidural Catheter[NCT05993273]75 participants (Anticipated)Interventional2023-04-05Recruiting
Cryoanalgesia and Post-thoracotomy Pain in Minimally Invasive Cardiothoracic Surgery[NCT05255146]100 participants (Anticipated)Interventional2023-12-31Not yet recruiting
The Effect of Cryoneurolysis for the Treatment of Acute Postoperative Pain Following Total Knee Arthroplasty in High Pain Responders - A Randomized, Participant- and Observer-masked, Sham-controlled Trial[NCT06088602]44 participants (Anticipated)Interventional2023-11-30Not yet recruiting
Phase II Multi-center Randomized Double-blind Placebo-controlled Efficacy and Dose Ranging Trial of the Drug Product Seroguard, Solution (JSC Pharmasyntez, Russia) Used for the Prevention of Pelvic Adhesions[NCT03660787]Phase 2114 participants (Actual)Interventional2017-05-04Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Anti-emetic / Intraoperative Fentanyl Administered (Measured in Micrograms)

The secondary outcomes that will be measured in this study include the amount of anti-emetic medication used in the first 24 hours post-op. This data will be attained by reviewing the medical record and through the validated survey questions. (NCT01602692)
Timeframe: Up to 24 hours following surgery

Interventionmicrograms (Mean)
Tumescent Solution With Dilute Epinephrine131.30
Tumescent Solution With Dilute Lidocaine and Epinephrine120.00

Time to Discharge

The patient's medical record will be reviewed to determine the time it took for the patient to be transitioned from the PACU (post anesthesia care unit) till discharge. This includes the time spent in the PACU, time spent in phase 2 and the total time to discharge. (NCT01602692)
Timeframe: Up to 24 hours following surgery

Interventionminutes (Mean)
Tumescent Solution With Dilute Epinephrine158
Tumescent Solution With Dilute Lidocaine and Epinephrine153

Unplanned Hospital Readmission

The patient's medical record will be reviewed to see if the patient was readmitted to the hospital (unplanned) due to complications related to this surgery. (NCT01602692)
Timeframe: Up to 1 week following surgery

InterventionParticipants (Count of Participants)
Tumescent Solution With Dilute Epinephrine0
Tumescent Solution With Dilute Lidocaine and Epinephrine0

Amount of Post-Operative Narcotic Medication Administered

Aim 1 is to determine the effect of dilute lidocaine in tumescent solution on post-operative pain following breast reduction surgery. The amount of narcotic medication administered (in Postanesthesia Care Unit (PACU), phase 2 and up to 24 hours post-op) determined by reviewing the medical record. (NCT01602692)
Timeframe: Up to 24 hours following surgery

,
Interventionmg (Mean)
PACU IV hydromorphoneFirst 24 hr Post-op oxycodone
Tumescent Solution With Dilute Epinephrine0.8932.19
Tumescent Solution With Dilute Lidocaine and Epinephrine0.5529.47

Anti-emetic / Intraoperative Medication Administered (mg)

The secondary outcomes that will be measured in this study include the amount of anti-emetic medication used in the first 24 hours post-op. This data will be attained by reviewing the medical record and through the validated survey questions. (NCT01602692)
Timeframe: Up to 24 hours following surgery

,
Interventionmg (Mean)
Mean Intraoperative hydromorphoneMean Intraoperative midazolamMean Intraoperative ketorolacMean Intraoperative dexamethasoneMean Intraoperative ondansetron
Tumescent Solution With Dilute Epinephrine0.982.0011.256.403.60
Tumescent Solution With Dilute Lidocaine and Epinephrine1.061.9016.506.004.05

Post Operative Nausea and Vomiting

The secondary outcomes that will be measured in this study include number of episodes of post-operative nausea (subjective feeling vs. emesis). This data will be attained by reviewing the medical record and through the validated survey questions. (NCT01602692)
Timeframe: Up to 24 hours following surgery

,
Interventionepisodes (Number)
NauseaVomiting
Tumescent Solution With Dilute Epinephrine82
Tumescent Solution With Dilute Lidocaine and Epinephrine104

Post-operative Pain

Aim 1 is to determine the effect of dilute lidocaine in tumescent solution on post-operative pain following breast reduction surgery. The data points that will be statistically compared will be pain scores determined via a validated pain survey (pain levels on a scale of 0-10 where 10 is the worst pain) and the amount of narcotic medication administered (in Postanesthesia Care Unit (PACU), phase 2 and up to 24 hours post-op) determined from responses to survey questions and by reviewing the medical record. (NCT01602692)
Timeframe: Up to 24 hours following surgery

,
Interventionscore on a scale (Mean)
End of PACU Mean Pain LevelFirst 24 hrs Post-op Mean Current PainFirst 24 hrs Post-op Mean Worst PainFirst 24 hrs Post-op Mean Least Pain
Tumescent Solution With Dilute Epinephrine5.474.006.442.00
Tumescent Solution With Dilute Lidocaine and Epinephrine4.474.286.682.53

Morphine Consumption

Morphine consumption over the first 24 hours (NCT01153503)
Timeframe: 24 hours post surgery

Interventionmg (Mean)
Ketorolac 30 mg, IV + TAP Block38.4
TAP Block38.6
Ketorolac 30 mg42.6

Change in Number of Participants in Detecting Pelvic Organs Limited Mobility

Absolute change of count of participants was measured with detecting pelvic organs limited mobility from the baseline (NCT03660787)
Timeframe: 30±4 days after surgery

Interventionparticipants (Number)
Placebo, 1.5 mL/kg-17
Placebo, 2.4 mL/kg-17
Seroguard, 1.5 mL/kg-21
Seroguard, 2.4 mL/kg-21

Change in Thickness of Pelvic Adhesions

The change from baseline was defined. It was evaluated by comparing baseline MRI data and repeated MRI data. Results were estimated according to scale from 0 to 3 where 0 - no adhesions, 1 - thin (filmy or filiform), 2 - marked, 3 - marked with an impaired passage through organs involved. (NCT03660787)
Timeframe: 30±4 days after surgery

Interventionscore on a scale (Median)
Placebo, 1.5 mL/kg0
Placebo, 2.4 mL/kg0
Seroguard, 1.5 mL/kg0
Seroguard, 2.4 mL/kg0

Change Number of Participants in Detecting Hyperechoic Linear Lesions

Frequency of detecting after repeated transvaginal ultrasound results was compared to baseline indications (4 or more) (NCT03660787)
Timeframe: 30±4 days after surgery

Interventionparticipants (Number)
Placebo, 1.5 mL/kg-17
Placebo, 2.4 mL/kg-16
Seroguard, 1.5 mL/kg-19
Seroguard, 2.4 mL/kg-18

Number of Participants With Detection of Hyperechoic Linear Lesions Post Surgery

The frequency was estimated based on transvaginal ultrasound results (NCT03660787)
Timeframe: 30±4 days after surgery

Interventionparticipants (Number)
Placebo, 1.5 mL/kg3
Placebo, 2.4 mL/kg2
Seroguard, 1.5 mL/kg1
Seroguard, 2.4 mL/kg3

Number of Participants With Detection of no Ultrasound Signs of Pelvic Adhesive Disease Post Surgery

No limited mobility of pelvic organs and no hyperechoic linear lesions should be shown (NCT03660787)
Timeframe: 30±4 days after surgery

InterventionParticipants (Count of Participants)
Placebo, 1.5 mL/kg19
Placebo, 2.4 mL/kg19
Seroguard, 1.5 mL/kg23
Seroguard, 2.4 mL/kg20

Number of Participants With Detection of Pelvic Organs Limited Mobility

The frequency was estimated based on transvaginal ultrasound results (NCT03660787)
Timeframe: 30±4 days after surgery

Interventionparticipants (Number)
Placebo, 1.5 mL/kg4
Placebo, 2.4 mL/kg4
Seroguard, 1.5 mL/kg0
Seroguard, 2.4 mL/kg2

Number of Participants With Reduction of Adhesions Number by 3 or More

The number of adhesions according to the first MRI data was compared to the number according to the data of second MRI (NCT03660787)
Timeframe: 30±4 days after surgical intervention

InterventionParticipants (Count of Participants)
Placebo, 1.5 mL/kg1
Placebo, 2.4 mL/kg1
Seroguard, 1.5 mL/kg10
Seroguard, 2.4 mL/kg10

Trials

60 trials available for bupivacaine and Nausea

ArticleYear
Comparing the efficacy of peritonsillar injection of bupivacaine and intravenous acetaminophen on post-tonsillectomy pain in children.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2022, Volume: 279, Issue:5

    Topics: Acetaminophen; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Double-Blind Method; Female

2022
Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Postoperative Pain Relief and Decrease Opioid Consumption: A Prospective Randomized Controlled Trial.
    The Clinical journal of pain, 2022, 06-01, Volume: 38, Issue:6

    Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; Humans;

2022
Comparison of low-dose morphine intrathecal analgesia and sufentanil PCIA in elderly patients with hip fracture undergoing single spinal anesthesia - a randomized clinical trial.
    BMC anesthesiology, 2022, 04-27, Volume: 22, Issue:1

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Spinal; Bupivacaine; Delirium;

2022
Addition of magnesium sulfate to bupivacaine improves analgesic efficacy after tonsillectomy: A randomized trial and a CONSORT analysis.
    European annals of otorhinolaryngology, head and neck diseases, 2022, Volume: 139, Issue:6

    Topics: Analgesics; Anesthetics, Local; Bupivacaine; Child; Double-Blind Method; Humans; Laryngismus; Magnes

2022
Randomized Clinical Trial Comparing Quadratus Lumborum Block and Intrathecal Morphine for Postcesarean Analgesia.
    Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2022, Volume: 44, Issue:12

    Topics: Analgesia; Anesthetics, Local; Bupivacaine; Cesarean Section; Double-Blind Method; Female; Humans; M

2022
Transmuscular Quadratus Lumborum Block Does Not Provide Significant Benefit for Primary Hip Arthroscopy with Pericapsular Infiltration: A Randomized Control Trial.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2023, Volume: 39, Issue:12

    Topics: Analgesics, Opioid; Anesthetics, Local; Arthroscopy; Bupivacaine; Femoracetabular Impingement; Human

2023
Dexmedetomidine as an Adjuvant to Bupivacaine in Caudal Analgesia in Children Undergoing Infra-Umbilical Surgery.
    Mymensingh medical journal : MMJ, 2023, Volume: 32, Issue:3

    Topics: Analgesia; Bangladesh; Bupivacaine; Child; Child, Preschool; Dexmedetomidine; Drug-Related Side Effe

2023
The Effect of Perianal Tramadol Infiltration on Postoperative Pain Following Hemorrhoidectomy.
    The American surgeon, 2022, Volume: 88, Issue:1

    Topics: Adult; Aged; Analgesics, Opioid; Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents, No

2022
Maintenance of the parturient in the left lateral position after spinal anesthesia with plain levobupivacaine for cesarean section reduces hypotension: a randomized study.
    Clinical and experimental obstetrics & gynecology, 2017, Volume: 44, Issue:1

    Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Section; Female; Humans; Hypote

2017
Comparison of intrathecal bupivacaine, levobupivacaine for cesarean section.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2014, Volume: 97, Issue:7

    Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Section; Double-Blind Method; F

2014
Efficacy of Local Anesthetic With Dexamethasone on the Quality of Recovery Following Total Extraperitoneal Bilateral Inguinal Hernia Repair: A Randomized Clinical Trial.
    JAMA surgery, 2016, 12-01, Volume: 151, Issue:12

    Topics: Aged; Analgesics, Opioid; Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacai

2016
Comparison of ropivacaine with and without fentanyl vs bupivacaine with fentanyl for postoperative epidural analgesia in bilateral total knee replacement surgery.
    Journal of clinical anesthesia, 2017, Volume: 37

    Topics: Aged; Amides; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, L

2017
The effect of peri-stomal infiltration with bupivacaine/epinephrine on post-operative pain, nausea and ease of surgery in reversal of loop ileostomies.
    International journal of colorectal disease, 2009, Volume: 24, Issue:12

    Topics: Adult; Aged; Bupivacaine; Demography; Epinephrine; Female; Humans; Ileostomy; Male; Middle Aged; Nau

2009
Antishivering effects of two different doses of intrathecal meperidine in caesarean section: a prospective randomised blinded study.
    European journal of anaesthesiology, 2011, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Loc

2011
Does the baricity of bupivacaine influence intrathecal spread in the prolonged sitting position before elective cesarean delivery? A prospective randomized controlled study.
    Anesthesia and analgesia, 2011, Volume: 113, Issue:4

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Sectio

2011
Three-in-one nerve block with different concentrations of bupivacaine in total knee arthroplasty: randomized, placebo-controlled, double-blind trial.
    The Journal of arthroplasty, 2012, Volume: 27, Issue:5

    Topics: Aged; Aged, 80 and over; Arthralgia; Arthroplasty, Replacement, Knee; Bupivacaine; Dose-Response Rel

2012
The analgesic effect of continuous subacromial bupivacaine infusion after arthroscopic shoulder surgery: a randomized controlled trial.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:2

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Arthro

2012
Ultrasound-guided transversus abdominal plane block with multimodal analgesia for pain management after total abdominal hysterectomy.
    Archives of gynecology and obstetrics, 2013, Volume: 288, Issue:1

    Topics: Abdominal Muscles; Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; An

2013
Ultrasound-guided transversus abdominal plane block with multimodal analgesia for pain management after total abdominal hysterectomy.
    Archives of gynecology and obstetrics, 2013, Volume: 288, Issue:1

    Topics: Abdominal Muscles; Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; An

2013
Ultrasound-guided transversus abdominal plane block with multimodal analgesia for pain management after total abdominal hysterectomy.
    Archives of gynecology and obstetrics, 2013, Volume: 288, Issue:1

    Topics: Abdominal Muscles; Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; An

2013
Ultrasound-guided transversus abdominal plane block with multimodal analgesia for pain management after total abdominal hysterectomy.
    Archives of gynecology and obstetrics, 2013, Volume: 288, Issue:1

    Topics: Abdominal Muscles; Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; An

2013
[The effect of intrathecal fentanyl added to hyperbaric bupivacaine for caesarean section].
    Masui. The Japanese journal of anesthesiology, 2003, Volume: 52, Issue:4

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Endotracheal; Anesthesia, Obstetrical; Anesthesia, Spinal;

2003
Analgesic effects of intrathecal neostigmine in perianal surgery.
    European journal of anaesthesiology, 2003, Volume: 20, Issue:5

    Topics: Anal Canal; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bradycardia; Bupivacaine;

2003
[Effect of different methods for postoperative pain management on catecholamine response to abdominal surgery].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2003, Apr-18, Volume: 35, Issue:2

    Topics: Abdomen; Amides; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid;

2003
Epidural levobupivacaine 0.1% or ropivacaine 0.1% combined with morphine provides comparable analgesia after abdominal surgery.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:2

    Topics: Abdomen; Aged; Amides; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, General; Anesthetics, Lo

2004
Perispinal analgesia for labour followed by patient-controlled infusion with bupivacaine and sufentanil: combined spinal-epidural vs. epidural analgesia alone.
    European journal of anaesthesiology, 2004, Volume: 21, Issue:3

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioi

2004
Efficacy and adverse effects of patient-controlled epidural or intravenous analgesia after major surgery.
    Chang Gung medical journal, 2004, Volume: 27, Issue:12

    Topics: Aged; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Intraveno

2004
[Low-dose 0.25% spinal levobupivacaine with epidural extension for cesarean section: comparison with 0.5% hyperbaric bupivacaine].
    Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:1

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local

2006
[Comparison of levobupivacaine, ropivacaine and racemic bupivacaine in patient-controlled epidural analgesia after cesarean section].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2006, Volume: 26, Issue:2

    Topics: Adult; Amides; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Bupivacai

2006
Oral sodium citrate increases nausea amongst elective Cesarean delivery patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:8

    Topics: Administration, Oral; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Intravenous;

2006
A randomized trial of crystalloid versus colloid solution for prevention of hypotension during spinal or low-dose combined spinal-epidural anesthesia for elective cesarean delivery.
    International journal of obstetric anesthesia, 2007, Volume: 16, Issue:1

    Topics: Adult; Analysis of Variance; Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics, Combined; Bupiva

2007
Intrathecal morphine reduces breakthrough pain during labour epidural analgesia.
    British journal of anaesthesia, 2007, Volume: 98, Issue:2

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthet

2007
Influence of injection rate of hyperbaric bupivacaine on spinal block in parturients: a randomized trial.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2007, Volume: 54, Issue:4

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Sectio

2007
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
    European journal of pain (London, England), 2008, Volume: 12, Issue:3

    Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;

2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
    European journal of pain (London, England), 2008, Volume: 12, Issue:3

    Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;

2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
    European journal of pain (London, England), 2008, Volume: 12, Issue:3

    Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;

2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
    European journal of pain (London, England), 2008, Volume: 12, Issue:3

    Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;

2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
    European journal of pain (London, England), 2008, Volume: 12, Issue:3

    Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;

2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
    European journal of pain (London, England), 2008, Volume: 12, Issue:3

    Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;

2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
    European journal of pain (London, England), 2008, Volume: 12, Issue:3

    Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;

2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
    European journal of pain (London, England), 2008, Volume: 12, Issue:3

    Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;

2008
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
    European journal of pain (London, England), 2008, Volume: 12, Issue:3

    Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female;

2008
Caudal analgesia with buprenorphine for postoperative pain relief in children.
    Paediatric anaesthesia, 1995, Volume: 5, Issue:2

    Topics: Abdomen; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Bupivaca

1995
Reduction of pain and nausea after laparoscopic sterilization with bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning.
    Obstetrics and gynecology, 1995, Volume: 85, Issue:5 Pt 1

    Topics: Analgesics, Non-Narcotic; Bupivacaine; Combined Modality Therapy; Female; Humans; Ketorolac; Laparos

1995
Technical problems and side effects associated with continuous intrathecal or epidural post-operative analgesia in patients undergoing hip arthroplasty.
    European journal of anaesthesiology, 1994, Volume: 11, Issue:6

    Topics: Aged; Aged, 80 and over; Analgesia; Analgesia, Epidural; Anesthesia, Spinal; Bupivacaine; Catheteriz

1994
Posture and the spread of hyperbaric bupivacaine in parturients using the combined spinal epidural technique.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:10

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthesia, Epidural; Anesthesia, Obstetrical; A

1993
Effects of retrobulbar bupivacaine on post-operative pain and nausea in retinal detachment surgery.
    Acta ophthalmologica, 1993, Volume: 71, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, General; Bupivacaine; Double-Blind Method; F

1993
Effect of tropisetron, a 5-HT3 receptor antagonist, on analgesia and nausea after intrathecal morphine.
    British journal of anaesthesia, 1993, Volume: 71, Issue:5

    Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Bupivacaine; Double-Blind Method; Female; Humans; Indol

1993
The influence of adrenaline on postoperative analgesia after subarachnoid morphine.
    Anaesthesia and intensive care, 1993, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, Intravenous; Anesthesia, Spinal; Bu

1993
Peribulbar injection of bupivacaine for the control of pain and nausea in vitreoretinal surgery.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1995, Volume: 30, Issue:6

    Topics: Anesthesia, General; Anesthetics, Local; Bupivacaine; Humans; Injections; Intraoperative Care; Middl

1995
A double-blinded evaluation of intraperitoneal bupivacaine vs saline for the reduction of postoperative pain and nausea after laparoscopic cholecystectomy.
    Surgical endoscopy, 1996, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupi

1996
Extraconal bupivacaine in scleral buckling procedures.
    Retina (Philadelphia, Pa.), 1996, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Anesthetics, Local; Bupivacaine; Female; Huma

1996
[Effect of the local anesthetic on visceral pain in cesarean sections done under intradural anesthesia].
    Revista espanola de anestesiologia y reanimacion, 1996, Volume: 43, Issue:1

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Sectio

1996
Bupivacaine decreases epidural meperidine requirements after abdominal surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:4

    Topics: Abdomen; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacai

1997
Intrathecal infusion of bupivacaine with or without morphine for postoperative analgesia after hip and knee arthroplasty.
    British journal of anaesthesia, 1997, Volume: 78, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind Me

1997
Epidural infusion of bupivacaine 0.0625% plus fentanyl 3.3 micrograms/ml provides better postoperative analgesia than patient-controlled analgesia with intravenous morphine after gynaecological laparotomy.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:5

    Topics: Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Bupivaca

1997
Patient-controlled analgesia after major shoulder surgery: patient-controlled interscalene analgesia versus patient-controlled analgesia.
    Anesthesiology, 1997, Volume: 87, Issue:6

    Topics: Analgesia, Patient-Controlled; Anesthetics, Local; Bupivacaine; Female; Humans; Male; Middle Aged; M

1997
Intrathecal pethidine: an alternative anaesthetic for transurethral resection of prostate?
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:6

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Do

1997
Nausea and vomiting after major arthroplasty with spinal anaesthesia including morphine: a randomised trial of subhypnotic propofol infusion as prophylaxis.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:1

    Topics: Aged; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Antiemetics; Arthroplasty, Replace

1998
Adding ketamine in a multimodal patient-controlled epidural regimen reduces postoperative pain and analgesic consumption.
    Anesthesia and analgesia, 1998, Volume: 86, Issue:6

    Topics: Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissociative; A

1998
The efficacy of intrathecal neostigmine, intrathecal morphine, and their combination for post-cesarean section analgesia.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:2

    Topics: Adult; Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cesarean Section; Female; Hu

1998
Subarachnoid and intravenous PCA versus bolus administration for postoperative pain relief in orthopaedic patients.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:10

    Topics: Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Inhalation; Anesthes

1998
Epidural naloxone reduces pruritus and nausea without affecting analgesia by epidural morphine in bupivacaine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2000, Volume: 47, Issue:1

    Topics: Adult; Analgesia, Epidural; Analgesics, Opioid; Bupivacaine; Dose-Response Relationship, Drug; Femal

2000
Combined spinal epidural for labour analgesia--duration, efficacy and side effects of adding sufentanil or fentanyl to bupivacaine intrathecally vs plain bupivacaine.
    Singapore medical journal, 1999, Volume: 40, Issue:10

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Female; Fentany

1999
The dose-range effects of sufentanil added to 0.125% bupivacaine on the quality of patient-controlled epidural analgesia during labor.
    Anesthesia and analgesia, 2001, Volume: 92, Issue:1

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioi

2001
[Comparison of ropivacaine and bupivacaine for epidural analgesia during labor].
    Revista espanola de anestesiologia y reanimacion, 2001, Volume: 48, Issue:5

    Topics: Adolescent; Adult; Amides; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Apgar Sc

2001
[The efficacy and safety of continuous epidural analgesia versus intradural-epidural analgesia during labor].
    Revista espanola de anestesiologia y reanimacion, 2001, Volume: 48, Issue:5

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthesia Recovery Period; Bupivacaine; Cesarea

2001
Intrathecal pethidine as sole anaesthetic agent for operative procedures of the lower limb, inguinal area and perineum.
    The West Indian medical journal, 2001, Volume: 50, Issue:4

    Topics: Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Lo

2001
[Caudal block in children: analgesia and respiratory effect of the combination bupivacaine-fentanyl].
    Annales francaises d'anesthesie et de reanimation, 1992, Volume: 11, Issue:2

    Topics: Anesthesia, Caudal; Bupivacaine; Child; Child, Preschool; Drug Combinations; Fentanyl; Humans; Nause

1992
Epidural hydromorphone for postcesarean analgesia.
    Obstetrics and gynecology, 1986, Volume: 68, Issue:1

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Cesarean Section; Double-Blind Me

1986
[Our experience in the use of hyperbaric 1 percent bupivacaine in 321 cases of spinal anesthesia in orthopedic and traumatologic surgery].
    Minerva anestesiologica, 1972, Volume: 38, Issue:1

    Topics: Adult; Aged; Anesthesia, Spinal; Blood Pressure; Bradycardia; Bupivacaine; Clinical Trials as Topic;

1972

Other Studies

26 other studies available for bupivacaine and Nausea

ArticleYear
Compression Regression: A Rare but Curable Cause of Postprandial Abdominal Pain.
    Digestive diseases and sciences, 2020, Volume: 65, Issue:2

    Topics: Abdominal Pain; Adult; Anesthetics, Local; Aortography; Bupivacaine; Celiac Plexus; Digestive System

2020
Quality of labour neuraxial analgesia and maternal satisfaction at a tertiary care teaching hospital: a prospective observational study.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:8

    Topics: Adjuvants, Anesthesia; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Contro

2013
The efficacy of continuous subcostal transversus abdominis plane block for analgesia after living liver donation: a retrospective study.
    Journal of anesthesia, 2016, Volume: 30, Issue:1

    Topics: Adult; Analgesia; Analgesics, Opioid; Bupivacaine; Female; Humans; Levobupivacaine; Liver Transplant

2016
Intrathecal hyperbaric versus isobaric bupivacaine for adult non-caesarean-section surgery: systematic review protocol.
    BMJ open, 2016, 05-18, Volume: 6, Issue:5

    Topics: Adult; Anesthesia, General; Anesthesia, Spinal; Bupivacaine; Databases, Bibliographic; Humans; Hypot

2016
Decreased postoperative pain, narcotic, and antiemetic use after breast reduction using a local anesthetic pain pump.
    Annals of plastic surgery, 2008, Volume: 61, Issue:2

    Topics: Adult; Antiemetics; Bupivacaine; Drug Delivery Systems; Female; Humans; Infusion Pumps, Implantable;

2008
Decreased postoperative pain, narcotic, and antiemetic use after breast reduction using a local anesthetic pain pump.
    Annals of plastic surgery, 2008, Volume: 61, Issue:2

    Topics: Adult; Antiemetics; Bupivacaine; Drug Delivery Systems; Female; Humans; Infusion Pumps, Implantable;

2008
Decreased postoperative pain, narcotic, and antiemetic use after breast reduction using a local anesthetic pain pump.
    Annals of plastic surgery, 2008, Volume: 61, Issue:2

    Topics: Adult; Antiemetics; Bupivacaine; Drug Delivery Systems; Female; Humans; Infusion Pumps, Implantable;

2008
Decreased postoperative pain, narcotic, and antiemetic use after breast reduction using a local anesthetic pain pump.
    Annals of plastic surgery, 2008, Volume: 61, Issue:2

    Topics: Adult; Antiemetics; Bupivacaine; Drug Delivery Systems; Female; Humans; Infusion Pumps, Implantable;

2008
A rare case of epidural catheter migration?
    Minerva anestesiologica, 2012, Volume: 78, Issue:7

    Topics: Adult; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Catheters; Cesarean Section; Female; F

2012
Can early post-spinal heart rate predict subsequent nausea during anaesthesia for caesarean section?
    International journal of obstetric anesthesia, 2012, Volume: 21, Issue:4

    Topics: Adrenergic alpha-1 Receptor Agonists; Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia

2012
Analgesic effects of intrathecal neostigmine.
    European journal of anaesthesiology, 2003, Volume: 20, Issue:12

    Topics: Analgesia; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Cholinesterase Inhibitors; Drug S

2003
Retrobulbar hemorrhage after sub-Tenon's anesthesia.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:9

    Topics: Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Connective Tissue; Diabet

2007
Prevention of retrobulbar hemorrhage after sub-Tenon anesthesia.
    Journal of cataract and refractive surgery, 2008, Volume: 34, Issue:3

    Topics: Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Connective Tissue; Diabet

2008
Postoperative epidural bupivacaine-morphine therapy. Experience with 4,227 surgical cancer patients.
    Anesthesiology, 1994, Volume: 81, Issue:2

    Topics: Adult; Aged; Analgesia, Epidural; Bupivacaine; Catheters, Indwelling; Drug Combinations; Female; Hum

1994
Pain management for children following selective dorsal rhizotomy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Bupiva

1994
Postoperative analgesia in children using continuous s.c. morphine.
    British journal of anaesthesia, 1993, Volume: 71, Issue:5

    Topics: Anesthesia, Epidural; Anesthesia, General; Bupivacaine; Child; Child, Preschool; Female; Humans; Inf

1993
[Continuous epidural buprenorphine for postoperative pain relief in patients after lower abdominal surgery].
    Masui. The Japanese journal of anesthesiology, 1993, Volume: 42, Issue:11

    Topics: Abdomen; Analgesia, Epidural; Bupivacaine; Buprenorphine; Female; Humans; Male; Middle Aged; Nausea;

1993
Intravenous ketamine or fentanyl prolongs postoperative analgesia after intrathecal neostigmine.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:4

    Topics: Analgesia; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Dissociative; Anesthetics, Intraveno

1996
Ambulatory laparoscopic fundoplication.
    Surgical endoscopy, 1997, Volume: 11, Issue:12

    Topics: Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anestheti

1997
Spinal anesthesia for elective lumbar spine surgery.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:8

    Topics: Anesthesia, General; Anesthesia, Spinal; Anesthetics, Local; Body Height; Body Weight; Bupivacaine;

1998
Neostigmine as the fourth spinal component for labor analgesia?
    Anesthesiology, 2000, Volume: 93, Issue:6

    Topics: Analgesia, Obstetrical; Analgesics; Bupivacaine; Clonidine; Drug Compounding; Drug Therapy, Combinat

2000
Central neural blockade and caesarian section. Part 1: Review and case series.
    Anaesthesia and intensive care, 1979, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Apgar Score; Bupivacaine; Cesarean

1979
The use of a retrobulbar anesthetic in managing pain and nausea from elevated intraocular pressure.
    Ophthalmic surgery, 1987, Volume: 18, Issue:7

    Topics: Anesthesia, Local; Bupivacaine; Female; Humans; Male; Middle Aged; Nausea; Ocular Hypertension; Pain

1987
Postpartum tubal ligation requires more bupivacaine for spinal anesthesia than does cesarean section.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:8

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Bupivacaine; Cesarean Section; Dose-Response Rel

1986
A clinical evaluation of the maternal effects of lumbar extradural analgesia for labour.
    Anaesthesia, 1974, Volume: 29, Issue:5

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Cesarean Section; Epinephrine; Extractio

1974
Continuous caudal block with the use of marcaine adrenaline 0.5 per cent for painless labour.
    Journal of postgraduate medicine, 1972, Volume: 18, Issue:3

    Topics: Analgesia; Anesthesia, Obstetrical; Apgar Score; Bupivacaine; Female; Fetus; Humans; Hypotension; La

1972
[Clinical study of the use of hyperbaric 1 per cent Bupivacaine in orthopedic and traumatologic interventions].
    Minerva anestesiologica, 1973, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthesia, Spinal; Bupivacaine; Female; Headache; Humans; Male; Middle Age

1973
Epidural analgesia for Caesarean section. A review of 182 cases.
    British journal of anaesthesia, 1973, Volume: 45, Issue:12

    Topics: Anesthesia, Epidural; Blood Pressure; Bupivacaine; Cesarean Section; Epinephrine; Ergonovine; Female

1973
Epidural analgesia in the treatment of bladder carcinoma. A technique using two catheters.
    Anaesthesia, 1974, Volume: 29, Issue:4

    Topics: Aged; Anesthesia, Epidural; Blood Pressure; Bupivacaine; Catheterization; Diazepam; Female; Humans;

1974