bupivacaine has been researched along with Myofascial Trigger Point Pain in 18 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ten patients with myofascial trigger point pain were entered into a double-blind cross-over study of the reversibility of myofascial trigger point injection (TPI) effects with naloxone versus placebo in order to test the hypothesis that the benefits of TPI are mediated, at least in part, through activation of an endogenous opioid system." | 5.06 | The effects of myofascial trigger point injections are naloxone reversible. ( Fine, PG; Hare, BD; Milano, R, 1988) |
| " In this report, we present the case of a 39-year-old man who experienced severe, transient hypokalemic paralysis in the context of TPI therapy with methylprednisolone, bupivacaine, and epinephrine." | 3.85 | A Case of Trigger-Point Injection-Induced Hypokalemic Paralysis. ( Bhattarai, M; Hudali, TH; Soriano, PK; Vogler, CN, 2017) |
| "Pain was assessed and 1 month posttreatment completion." | 2.80 | A pilot randomized trial of levator injections versus physical therapy for treatment of pelvic floor myalgia and sexual pain. ( Karram, M; Maxwell, R; Shah, A; South, M; Sroga, J; Whiteside, J; Zoorob, D, 2015) |
| "Lidocaine patches were effective in, and highly acceptable to, these patients with MPS and high tissue hypersensitivity." | 2.74 | A randomized, controlled study comparing a lidocaine patch, a placebo patch, and anesthetic injection for treatment of trigger points in patients with myofascial pain syndrome: evaluation of pain and somatic pain thresholds. ( Affaitati, G; Costantini, R; Fabrizio, A; Giamberardino, MA; Lapenna, D; Lerza, R; Savini, A; Tafuri, E, 2009) |
| "Myofascial pain syndromes are characterized by the presence of painful loci within muscles, tendons or ligaments, called trigger points." | 2.73 | Comparison between newer local anesthetics for myofascial pain syndrome management. ( Amaniti, EN; Gorgias, NK; Maidatsi, PG; Vasilakos, DF; Zaralidou, AT, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (33.33) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bautista, A | 1 |
| Webb, C | 1 |
| Rosenquist, R | 1 |
| Soriano, PK | 1 |
| Bhattarai, M | 1 |
| Vogler, CN | 1 |
| Hudali, TH | 1 |
| Metin Ökmen, B | 1 |
| Ökmen, K | 1 |
| Altan, L | 1 |
| Zoorob, D | 1 |
| South, M | 1 |
| Karram, M | 1 |
| Sroga, J | 1 |
| Maxwell, R | 1 |
| Shah, A | 1 |
| Whiteside, J | 1 |
| Affaitati, G | 1 |
| Fabrizio, A | 1 |
| Savini, A | 1 |
| Lerza, R | 1 |
| Tafuri, E | 1 |
| Costantini, R | 1 |
| Lapenna, D | 1 |
| Giamberardino, MA | 1 |
| Langford, CF | 1 |
| Udvari Nagy, S | 1 |
| Ghoniem, GM | 1 |
| Jordá Sanz, L | 1 |
| Gallego García, J | 1 |
| León Carsí, I | 1 |
| Abengochea Cotaina, A | 1 |
| Zaralidou, AT | 1 |
| Amaniti, EN | 1 |
| Maidatsi, PG | 1 |
| Gorgias, NK | 1 |
| Vasilakos, DF | 1 |
| Ju, H | 1 |
| Feng, Y | 1 |
| Yang, BX | 1 |
| Wang, J | 1 |
| Minty, R | 1 |
| Kelly, L | 1 |
| Minty, A | 1 |
| Slocumb, JC | 1 |
| Hendler, N | 1 |
| Fink, H | 1 |
| Long, D | 1 |
| Weed, ND | 1 |
| Hameroff, SR | 1 |
| Crago, BR | 1 |
| Blitt, CD | 1 |
| Womble, J | 1 |
| Kanel, J | 1 |
| Hopwood, MB | 1 |
| Abram, SE | 1 |
| Pippa, P | 1 |
| Allegra, A | 1 |
| Cirillo, L | 1 |
| Doni, L | 1 |
| Rivituso, C | 1 |
| Fine, PG | 2 |
| Milano, R | 1 |
| Hare, BD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intratissue Percutaneous Electrolysis Technique vs. Manual Therapy in Women With Dyspareunia and Pelvic Pain[NCT03163160] | 60 participants (Actual) | Interventional | 2017-06-20 | Completed | |||
| A Randomized Controlled Study Comparing Trigger Point Injections With 1% Lidocaine Versus 5% Lidocaine Patch for Myofascial Pain in the Emergency Department[NCT05151510] | Phase 4 | 110 participants (Anticipated) | Interventional | 2021-11-01 | Recruiting | ||
| Assessment Of Pain Subsidence And Sexual Function Amelioration Using Either Pelvic Rehabilitation Or Trigger Point Injections[NCT02022722] | Phase 4 | 36 participants (Anticipated) | Interventional | 2013-08-31 | Recruiting | ||
| Pain Control After VATS Anatomical Pulmonary Resections: Randomized Comparison Between Cryoanalgesia, Erector Spinae Plane Block and Epidural Catheter[NCT05993273] | 75 participants (Anticipated) | Interventional | 2023-04-05 | Recruiting | |||
| Cryoanalgesia and Post-thoracotomy Pain in Minimally Invasive Cardiothoracic Surgery[NCT05255146] | 100 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting | |||
| The Effect of Cryoneurolysis for the Treatment of Acute Postoperative Pain Following Total Knee Arthroplasty in High Pain Responders - A Randomized, Participant- and Observer-masked, Sham-controlled Trial[NCT06088602] | 44 participants (Anticipated) | Interventional | 2023-11-30 | Not yet recruiting | |||
| Double-blind, Prospective Comparison of Medications Used in Trigger Point Injections - Ketorolac, Lidocaine, or Dexamethasone[NCT03028012] | Phase 4 | 10 participants (Actual) | Interventional | 2017-05-02 | Terminated (stopped due to Poor enrollment.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Participants in this study underwent TPIs by the following method. The needle was inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. This was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain, one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Post Injections Up to Three Months
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketorolac | 1 |
| Lidocaine | 0 |
| Dexamethasone | 0 |
The BPI was evaluated on a scale from 0-10. Zero would mean no interference and 10 would be calculated at complete interferences. We used a 7-point questionnaire about pain. All scores were calculated at baseline and three months. (NCT03028012)
Timeframe: Baseline and Three Months
| Intervention | score on a scale (Number) | |||
|---|---|---|---|---|
| Participant Number #3 at Baseline | Participant Number #3 at 3 Months | Participant Number #8 at Baseline | Participant #8 at 3 Months | |
| Ketorolac | 8 | 3 | 5 | 3 |
TPI were treated with a needle inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. Such was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain,one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Injection and Three Month Post Injection(s)
| Intervention | score on a scale (Number) | |||
|---|---|---|---|---|
| Participant Number 3 at Baseline | Participant Number 3 at 3 Months | Participant Number 8 at Baseline | Participant Number 8 at 3 Months | |
| Ketorolac | 8 | 3 | 5 | 3 |
1 review available for bupivacaine and Myofascial Trigger Point Pain
| Article | Year |
|---|---|
The occasional trigger point injection.
Topics: Anesthetics, Local; Bupivacaine; Humans; Injections, Intramuscular; Myofascial Pain Syndromes | 2007 |
9 trials available for bupivacaine and Myofascial Trigger Point Pain
| Article | Year |
|---|---|
Comparison of the Efficiency of Ultrasound-Guided Injections of the Rhomboid Major and Trapezius Muscles in Myofascial Pain Syndrome: A Prospective Randomized Controlled Double-blind Study.
Topics: Adult; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Injections; Male; Myofa | 2018 |
A pilot randomized trial of levator injections versus physical therapy for treatment of pelvic floor myalgia and sexual pain.
Topics: Adult; Anesthetics, Local; Anus Diseases; Bupivacaine; Female; Glucocorticoids; Humans; Injections; | 2015 |
A randomized, controlled study comparing a lidocaine patch, a placebo patch, and anesthetic injection for treatment of trigger points in patients with myofascial pain syndrome: evaluation of pain and somatic pain thresholds.
Topics: Administration, Cutaneous; Adult; Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female | 2009 |
Levator ani trigger point injections: An underutilized treatment for chronic pelvic pain.
Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Anus Diseases; Bupivacaine; Chronic Disea | 2007 |
Comparison between newer local anesthetics for myofascial pain syndrome management.
Topics: Adult; Amides; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Injections, Int | 2007 |
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female; | 2008 |
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female; | 2008 |
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female; | 2008 |
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female; | 2008 |
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female; | 2008 |
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female; | 2008 |
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female; | 2008 |
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female; | 2008 |
Comparison of epidural analgesia and intercostal nerve cryoanalgesia for post-thoracotomy pain control.
Topics: Aged; Analgesia; Analgesia, Epidural; Analgesics; Bupivacaine; Chronic Disease; Cryotherapy; Female; | 2008 |
Comparison of bupivacaine, etidocaine, and saline for trigger-point therapy.
Topics: Acetanilides; Bupivacaine; Clinical Trials as Topic; Double-Blind Method; Etidocaine; Humans; Inject | 1981 |
Factors associated with failure of trigger point injections.
Topics: Adult; Bupivacaine; Female; Humans; Injections; Lidocaine; Male; Middle Aged; Myofascial Pain Syndro | 1994 |
The effects of myofascial trigger point injections are naloxone reversible.
Topics: Adult; Bupivacaine; Double-Blind Method; Endorphins; Female; Humans; Male; Myofascial Pain Syndromes | 1988 |
8 other studies available for bupivacaine and Myofascial Trigger Point Pain
| Article | Year |
|---|---|
Serratus Anterior Muscle Pain Syndrome: A Diagnostic Conundrum.
Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Chest Pain; Female; Humans; Inject | 2017 |
A Case of Trigger-Point Injection-Induced Hypokalemic Paralysis.
Topics: Adult; Anesthetics, Local; Bupivacaine; Glucocorticoids; Humans; Hypokalemia; Injections, Intramuscu | 2017 |
[Blood patch in a patient with postdural puncture headache].
Topics: Accidents; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Bed Rest; Betamet | 2006 |
Neurological factors in chronic pelvic pain: trigger points and the abdominal pelvic pain syndrome.
Topics: Abdomen; Abdominal Muscles; Adolescent; Adult; Aged; Anesthesia, Local; Bupivacaine; Chronic Disease | 1984 |
Myofascial syndrome: response to trigger-point injections.
Topics: Adult; Bupivacaine; Electromyography; Female; Humans; Male; Middle Aged; Myofascial Pain Syndromes | 1983 |
When shoulder pain isn't bursitis. The myofascial pain syndrome.
Topics: Bupivacaine; Bursitis; Diagnosis, Differential; Feedback; Humans; Lidocaine; Muscles; Myofascial Pai | 1983 |
[Fibromyalgia and trigger points].
Topics: Adolescent; Bupivacaine; Female; Fibromyalgia; Humans; Myofascial Pain Syndromes | 1994 |
Myofascial trigger point pain in children.
Topics: Anesthesia, Local; Bupivacaine; Child; Diagnosis, Differential; Groin; Humans; Male; Myofascial Pain | 1987 |