bupivacaine has been researched along with Muscle Disorders in 44 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "LLLT, at the dose used, reduced fibrosis and myonecrosis in the sternomastoid muscle triggered by bupivacaine, accelerating the muscle regeneration process." | 7.85 | Low-level laser therapy (LLLT) accelerates the sternomastoid muscle regeneration process after myonecrosis due to bupivacaine. ( Alessi Pissulin, CN; Henrique Fernandes, AA; Michelin Matheus, SM; Rossi E Silva, RC; Sanchez Orellana, AM, 2017) |
| "To determine how and when the satellite cells are stimulated to replicate in muscle regeneration, the rat soleus muscle was examined chronologically after bupivacaine-induced myonecrosis." | 7.69 | Initiation of satellite cell replication in bupivacaine-induced myonecrosis. ( Nonaka, I; Saito, Y, 1994) |
| "Immunohistochemical analysis of the inflammatory cells and complement C3 in the rat skeletal muscle was performed chronologically in bupivacaine-induced myonecrosis." | 7.68 | Analysis of inflammatory cells and complement C3 in bupivacaine-induced myonecrosis. ( Arahata, K; Hiyamuta, E; Orimo, S; Sugita, H, 1991) |
| "LLLT, at the dose used, reduced fibrosis and myonecrosis in the sternomastoid muscle triggered by bupivacaine, accelerating the muscle regeneration process." | 3.85 | Low-level laser therapy (LLLT) accelerates the sternomastoid muscle regeneration process after myonecrosis due to bupivacaine. ( Alessi Pissulin, CN; Henrique Fernandes, AA; Michelin Matheus, SM; Rossi E Silva, RC; Sanchez Orellana, AM, 2017) |
| "In a period of 4 wk after peripheral nerve block, both long-acting local anesthetics, bupivacaine and ropivacaine, produced calcific myonecrosis suggestive of irreversible skeletal muscle damage." | 3.73 | The long term myotoxic effects of bupivacaine and ropivacaine after continuous peripheral nerve blocks. ( Bohl, JRE; Graf, BM; Hacke, N; Martin, E; Sinner, B; Zink, W, 2005) |
| "The aim of the study was to observe the effect of coenzyme Q10 and vitamin E supplementation on the course of the regeneration process of the longissimus lumborum muscle after bupivacaine-induced myonecrosis as well as to determine the correlation between the level of those substances in plasma and their levels in damaged and non-damaged muscular tissue in pigs." | 3.72 | The effect of coenzyme Q10 and vitamin E on the regeneration of skeletal muscles in pigs. ( Babińska, I; Karpińska, J; Kasperowicz, B; Mikołajczyk, A; Otrocka-Domagała, I; Purzyńska-Pugacewicz, A; Rotkiewicz, T, 2004) |
| "To determine how and when the satellite cells are stimulated to replicate in muscle regeneration, the rat soleus muscle was examined chronologically after bupivacaine-induced myonecrosis." | 3.69 | Initiation of satellite cell replication in bupivacaine-induced myonecrosis. ( Nonaka, I; Saito, Y, 1994) |
| "Immunohistochemical analysis of the inflammatory cells and complement C3 in the rat skeletal muscle was performed chronologically in bupivacaine-induced myonecrosis." | 3.68 | Analysis of inflammatory cells and complement C3 in bupivacaine-induced myonecrosis. ( Arahata, K; Hiyamuta, E; Orimo, S; Sugita, H, 1991) |
| "To examine the behavior of transverse (T)-tubule formation in experimentally-induced regenerating fibers, a local anesthetic, bupivacaine hydrochloride, was injected directly into the rat soleus muscle to cause myonecrosis." | 3.67 | Behavior of sarcotubular system formation in experimentally induced regeneration of muscle fibers. ( Ishitsu, T; Miike, T; Nonaka, I; Ohtani, Y; Tamari, H, 1984) |
| "The guanethidine blockade was evaluated 24 h after the injection by counting TePs and by assessment of rest pain in the hand and forearm." | 2.66 | Regional sympathetic blockade in primary fibromyalgia. ( Bengtsson, A; Bengtsson, M, 1988) |
| "The duration of postsurgical pain greatly outlasts the duration of analgesia (typically < 12 h) following single administration of traditional formulations of local anesthetics." | 2.49 | Liposome bupivacaine in peripheral nerve blocks and epidural injections to manage postoperative pain. ( Ilfeld, BM, 2013) |
| "Bupivacaine was more myotoxic than other anesthetic agents and increased apoptosis." | 1.51 | Comparison of myotoxic effects of levobupivacaine, bupivacaine and ropivacaine: apoptotic activity and acute effect on pro-inflammatory cytokines. ( Aksu, R; Balcıoglu, E; Bayram, A; Coşkun, G; Gergin, IS; Oz Gergin, O; Polat, S; Soyer Sarıca, Z; Yay, A; Yıldız, K, 2019) |
| "Bupivacaine treatment caused severe tissue damage (score, 2." | 1.32 | The acute myotoxic effects of bupivacaine and ropivacaine after continuous peripheral nerve blockades. ( Bohl, JRE; Braun, PM; Fink, RHA; Graf, BM; Hacke, N; Martin, E; Seif, C; Sinner, B; Zink, W, 2003) |
| "Cycloheximide inhibited the increase in lysosomal enzymes in bupivacaine-treated muscle." | 1.27 | Effect of cycloheximide administration on bupivacaine-induced acute muscle degradation. ( Fujita, T; Ishiura, S; Nonaka, I; Sugita, H, 1983) |
| "Immediate relief of pain is experienced after the solution of local anaesthetic and steroid has been deposited deep within the fleshy portion of the muscle." | 1.26 | Chronic pain syndromes and their treatment. III. The piriformis syndrome. ( Wyant, GM, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (29.55) | 18.7374 |
| 1990's | 5 (11.36) | 18.2507 |
| 2000's | 10 (22.73) | 29.6817 |
| 2010's | 13 (29.55) | 24.3611 |
| 2020's | 3 (6.82) | 2.80 |
| Authors | Studies |
|---|---|
| Mao, Q | 1 |
| Yu, W | 1 |
| Liu, S | 1 |
| Cao, X | 1 |
| Dai, Y | 1 |
| Zhang, X | 1 |
| Min, X | 1 |
| Liu, L | 1 |
| Ding, Z | 1 |
| Fukuda, K | 1 |
| Kuroda, T | 1 |
| Tamura, N | 1 |
| Mita, H | 1 |
| Miyata, H | 1 |
| Kasashima, Y | 1 |
| Li, X | 1 |
| Zhao, J | 1 |
| Lv, Q | 1 |
| Tian, Y | 1 |
| Zhang, L | 3 |
| Liu, T | 3 |
| Zou, D | 2 |
| Chen, Y | 2 |
| Lu, Z | 1 |
| Yan, J | 1 |
| Chen, D | 1 |
| Xu, Y | 1 |
| Zhang, J | 1 |
| Bai, Y | 1 |
| Huo, Z | 1 |
| Cooke, MB | 1 |
| Rybalka, E | 1 |
| Stathis, CG | 1 |
| Hayes, A | 1 |
| Oz Gergin, O | 1 |
| Bayram, A | 1 |
| Gergin, IS | 1 |
| Aksu, R | 1 |
| Yay, A | 1 |
| Balcıoglu, E | 1 |
| Polat, S | 1 |
| Coşkun, G | 1 |
| Soyer Sarıca, Z | 1 |
| Yıldız, K | 1 |
| Shibaguchi, T | 1 |
| Hoshi, M | 1 |
| Yoshihara, T | 1 |
| Naito, H | 1 |
| Goto, K | 1 |
| Yoshioka, T | 1 |
| Sugiura, T | 1 |
| Hofmann, P | 2 |
| Metterlein, T | 2 |
| Bollwein, G | 2 |
| Gruber, M | 2 |
| Plank, C | 2 |
| Graf, BM | 4 |
| Zink, W | 4 |
| Ilfeld, BM | 1 |
| Otrocka-Domagała, I | 3 |
| Mikołajczyk, A | 2 |
| Paździor-Czapula, K | 1 |
| Gesek, M | 1 |
| Rotkiewicz, T | 3 |
| Mikiewicz, M | 1 |
| Peng, Y | 1 |
| Alessi Pissulin, CN | 1 |
| Henrique Fernandes, AA | 1 |
| Sanchez Orellana, AM | 1 |
| Rossi E Silva, RC | 1 |
| Michelin Matheus, SM | 1 |
| Sethuraman, M | 1 |
| Neema, PK | 1 |
| Rathod, RC | 1 |
| Podbielski, M | 1 |
| Wiśniewska, A | 1 |
| Drzewiecka, A | 1 |
| Danieli-Betto, D | 1 |
| Peron, S | 1 |
| Germinario, E | 1 |
| Zanin, M | 1 |
| Sorci, G | 1 |
| Franzoso, S | 1 |
| Sandonà, D | 1 |
| Betto, R | 1 |
| Nouette-Gaulain, K | 1 |
| Bringuier, S | 1 |
| Canal-Raffin, M | 1 |
| Bernard, N | 1 |
| Lopez, S | 1 |
| Dadure, C | 1 |
| Masson, F | 1 |
| Mercier, J | 1 |
| Sztark, F | 1 |
| Rossignol, R | 1 |
| Capdevila, X | 1 |
| Cereda, CM | 1 |
| Tofoli, GR | 1 |
| Maturana, LG | 1 |
| Pierucci, A | 1 |
| Nunes, LA | 1 |
| Franz-Montan, M | 1 |
| de Oliveira, AL | 1 |
| Arana, S | 1 |
| de Araujo, DR | 1 |
| de Paula, E | 1 |
| Seif, C | 1 |
| Bohl, JRE | 2 |
| Hacke, N | 2 |
| Braun, PM | 1 |
| Sinner, B | 2 |
| Martin, E | 2 |
| Fink, RHA | 1 |
| Karpińska, J | 1 |
| Purzyńska-Pugacewicz, A | 1 |
| Kasperowicz, B | 1 |
| Babińska, I | 1 |
| Plant, DR | 2 |
| Colarossi, FE | 1 |
| Lynch, GS | 2 |
| Hirata, M | 1 |
| Sakuma, K | 1 |
| Okajima, S | 1 |
| Fujiwara, H | 1 |
| Inashima, S | 1 |
| Yasuhara, M | 1 |
| Kubo, T | 1 |
| Vignaud, A | 1 |
| Hourdé, C | 1 |
| Butler-Browne, G | 1 |
| Ferry, A | 1 |
| Knab, J | 1 |
| Heupel, EW | 1 |
| Steinmann, D | 1 |
| Ryall, JG | 1 |
| Schertzer, JD | 1 |
| Alabakis, TM | 1 |
| Gehrig, SM | 1 |
| Miike, T | 1 |
| Nonaka, I | 4 |
| Ohtani, Y | 1 |
| Tamari, H | 1 |
| Ishitsu, T | 1 |
| Nolte, H | 1 |
| Ishiura, S | 2 |
| Nakase, H | 1 |
| Tsuchiya, K | 1 |
| Okada, S | 1 |
| Sugita, H | 3 |
| Fujita, T | 1 |
| Kalso, EA | 1 |
| Lalla, ML | 1 |
| Rosenberg, PH | 1 |
| Tuominen, MK | 1 |
| Santavirta, S | 1 |
| Gripenberg, J | 1 |
| Holmboe, J | 1 |
| Kongsrud, F | 1 |
| Saito, Y | 1 |
| Hogan, Q | 1 |
| Dotson, R | 1 |
| Erickson, S | 1 |
| Kettler, R | 1 |
| Hogan, K | 1 |
| Mizel, MS | 1 |
| Michelson, JD | 1 |
| Newberg, A | 1 |
| Wyant, GM | 1 |
| Jirmanová, I | 1 |
| Orimo, S | 1 |
| Hiyamuta, E | 1 |
| Arahata, K | 1 |
| Kamińska, A | 1 |
| Fidziańska, A | 1 |
| Sadeh, M | 1 |
| Czyewski, K | 1 |
| Stern, LZ | 1 |
| Bengtsson, A | 1 |
| Bengtsson, M | 1 |
| Steer, JH | 1 |
| Mastaglia, FL | 1 |
| Papadimitriou, JM | 1 |
| Van Bruggen, I | 1 |
| Wakayama, Y | 1 |
| Shibuya, S | 1 |
| Roy-Shapira, A | 1 |
| Amoury, RA | 1 |
| Ashcraft, KW | 1 |
| Holder, TM | 1 |
| Sharp, RJ | 1 |
2 reviews available for bupivacaine and Muscle Disorders
| Article | Year |
|---|---|
Liposome bupivacaine in peripheral nerve blocks and epidural injections to manage postoperative pain.
Topics: Anesthetics, Local; Animals; Bupivacaine; Humans; Injections, Epidural; Liposomes; Muscular Diseases | 2013 |
Local anesthetic myotoxicity: a case and review.
Topics: Adult; Anesthesia, Local; Bupivacaine; Female; Humans; Infant, Newborn; Muscular Diseases | 1994 |
2 trials available for bupivacaine and Muscle Disorders
| Article | Year |
|---|---|
Effect of butaphosphane and cyanocobalamin on regeneration of muscle fibres in pigs.
Topics: Animals; Bupivacaine; Muscle Fibers, Skeletal; Muscular Diseases; Necrosis; Organophosphonates; Orga | 2009 |
Regional sympathetic blockade in primary fibromyalgia.
Topics: Adult; Autonomic Nerve Block; Bupivacaine; Female; Ganglia, Sympathetic; Guanethidine; Humans; Injec | 1988 |
40 other studies available for bupivacaine and Muscle Disorders
| Article | Year |
|---|---|
Downregulation of HSPA12A underlies myotoxicity of local anesthetic agent bupivacaine through inhibiting PGC1α-mediated mitochondrial integrity.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cell Line; Cell Survival; Down-Regulation; Gene Expression | 2022 |
Platelet Lysate Enhances Equine Skeletal Muscle Regeneration in A Bupivacaine-Induced Muscle Injury Model
Topics: Animals; Bupivacaine; Euthanasia, Animal; Horse Diseases; Horses; Muscle, Skeletal; Muscular Disease | 2022 |
Electroacupuncture alleviates multifidus muscle injury by modulating mitochondrial function and Ca
Topics: Adenosine Triphosphate; Animals; Bupivacaine; Calcium; Electroacupuncture; Mitochondria; Muscular Di | 2023 |
[Effects of electroacupuncture at "Weizhong" (BL 40) on morphology and expression of CK and IL-17 in rats with bupivacaine-induced multifidus muscle injury].
Topics: Acupuncture Points; Anesthetics, Local; Animals; Bupivacaine; Creatine Kinase; Electroacupuncture; I | 2017 |
Myoprotective Potential of Creatine Is Greater than Whey Protein after Chemically-Induced Damage in Rat Skeletal Muscle.
Topics: Animals; Bupivacaine; Creatine; Cytoprotection; Dietary Supplements; Disease Models, Animal; Isometr | 2018 |
Comparison of myotoxic effects of levobupivacaine, bupivacaine and ropivacaine: apoptotic activity and acute effect on pro-inflammatory cytokines.
Topics: Anesthetics, Local; Animals; Apoptosis; Bupivacaine; Cytokines; Gene Expression Regulation; Immunohi | 2019 |
Impact of different temperature stimuli on the expression of myosin heavy chain isoforms during recovery from bupivacaine-induced muscle injury in rats.
Topics: Animals; Bupivacaine; Heat Stress Disorders; Male; Muscle Fibers, Skeletal; Muscular Diseases; Myosi | 2019 |
The myotoxic effect of bupivacaine and ropivacaine on myotubes in primary mouse cell culture and an immortalized cell line.
Topics: Amides; Anesthetics, Local; Animals; Apoptosis; Bupivacaine; Cell Death; Cell Line; Cell Survival; C | 2013 |
Modification of Bupivacaine-Induced Myotoxicity with Dantrolene and Caffeine In Vitro.
Topics: Anesthetics, Local; Animals; Annexins; Bupivacaine; Caffeine; Central Nervous System Stimulants; Dan | 2016 |
Effect of low-energy laser irradiation and antioxidant supplementation on cell apoptosis during skeletal muscle post-injury regeneration in pigs.
Topics: Animals; Antioxidants; Apoptosis; Bupivacaine; Dose-Response Relationship, Radiation; Drug Therapy, | 2015 |
[Effects of electroacupuncture at "Weizhong" (BL 40) on regeneration and morphology in rats with bupivacaine-induced multifidus muscle injury].
Topics: Acupuncture Points; Anesthetics, Local; Animals; Bupivacaine; Electroacupuncture; Humans; Male; Musc | 2016 |
Low-level laser therapy (LLLT) accelerates the sternomastoid muscle regeneration process after myonecrosis due to bupivacaine.
Topics: Animals; Bupivacaine; Fibrosis; Low-Level Light Therapy; Muscular Diseases; Neck Muscles; Necrosis; | 2017 |
Combined monitored anesthesia care and femoral nerve block for muscle biopsy in children with myopathies.
Topics: Adjuvants, Anesthesia; Anesthesia; Anesthetics, Combined; Anesthetics, Local; Atropine; Biopsy; Bupi | 2008 |
Sphingosine 1-phosphate signaling is involved in skeletal muscle regeneration.
Topics: Animals; Bupivacaine; Cell Membrane; Cell Proliferation; Cells, Cultured; Disease Models, Animal; In | 2010 |
Time course of mitochondrial metabolism alterations to repeated injections of bupivacaine in rat muscle.
Topics: Adenosine Diphosphate; Anesthetics, Local; Animals; Bupivacaine; Citrate (si)-Synthase; Electron Tra | 2010 |
Local neurotoxicity and myotoxicity evaluation of cyclodextrin complexes of bupivacaine and ropivacaine.
Topics: Amides; Animals; Animals, Newborn; Bupivacaine; Cells, Cultured; Cyclodextrins; Drug Evaluation, Pre | 2012 |
The acute myotoxic effects of bupivacaine and ropivacaine after continuous peripheral nerve blockades.
Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Edema; Female; In Situ Nick-End Labeling; Microsco | 2003 |
The effect of coenzyme Q10 and vitamin E on the regeneration of skeletal muscles in pigs.
Topics: Anesthetics, Local; Animal Feed; Animals; Antioxidants; Bupivacaine; Coenzymes; Female; Muscle, Skel | 2004 |
The long term myotoxic effects of bupivacaine and ropivacaine after continuous peripheral nerve blocks.
Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Muscle Cells; Muscle Fibers, Skeletal; Muscle, Ske | 2005 |
Notexin causes greater myotoxic damage and slower functional repair in mouse skeletal muscles than bupivacaine.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cell Death; Cytotoxins; Disease Models, Animal; Elapid Ven | 2006 |
Increased expression of neuregulin-1 in differentiating muscle satellite cells and in motoneurons during muscle regeneration.
Topics: Anesthetics, Local; Animals; Bromodeoxyuridine; Bungarotoxins; Bupivacaine; Cell Differentiation; Dy | 2007 |
Differential recovery of neuromuscular function after nerve/muscle injury induced by crude venom from Notechis scutatus, cardiotoxin from Naja atra and bupivacaine treatments in mice.
Topics: Analysis of Variance; Animals; Bupivacaine; Cobra Cardiotoxin Proteins; Elapid Venoms; Male; Mice; M | 2007 |
Anesthesia for orthopedic surgery in Pallister-Killian syndrome.
Topics: Abnormalities, Multiple; Alfentanil; Androstanols; Anesthesia; Anesthesia, Epidural; Anesthetics, Co | 2008 |
Intramuscular beta2-agonist administration enhances early regeneration and functional repair in rat skeletal muscle after myotoxic injury.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Anesthetics, Local; Animals; Blotting | 2008 |
Behavior of sarcotubular system formation in experimentally induced regeneration of muscle fibers.
Topics: Animals; Bupivacaine; Microscopy, Electron; Microtubules; Muscles; Muscular Diseases; Myofibrils; Ne | 1984 |
The role of spinal anesthesia today.
Topics: Anesthesia, Spinal; Bupivacaine; Headache; Humans; Intestinal Diseases; Muscular Diseases; Nerve Blo | 1984 |
Immunocytochemical localization of cathepsin B in degenerating rat skeletal muscle induced by a local anesthetic, bupivacaine.
Topics: Animals; Bupivacaine; Cathepsin B; Cathepsins; Histocytochemistry; Immunochemistry; Muscular Disease | 1983 |
Effect of cycloheximide administration on bupivacaine-induced acute muscle degradation.
Topics: Animals; Bupivacaine; Cathepsin B; Cathepsin L; Cathepsins; Cycloheximide; Cysteine Endopeptidases; | 1983 |
Evaluation of the myotoxicity of bupivacaine in bier blocks--a biochemical and electron microscopic study.
Topics: Adult; Aged; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Intravenous; Arm; Bupivacaine; | 1983 |
Delayed respiratory arrest after bupivacaine.
Topics: Anesthesia, Epidural; Bupivacaine; Hernia, Inguinal; Humans; Male; Middle Aged; Muscular Diseases; P | 1982 |
Initiation of satellite cell replication in bupivacaine-induced myonecrosis.
Topics: Animals; Bromodeoxyuridine; Bupivacaine; Cell Division; Desmin; Muscles; Muscular Diseases; Necrosis | 1994 |
Peroneal tendon bupivacaine injection: utility of concomitant injection of contrast material.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Bupivacaine; Contrast Media; Drug Combinations; Female; | 1996 |
Chronic pain syndromes and their treatment. III. The piriformis syndrome.
Topics: Adult; Anesthetics, Local; Back Pain; Bupivacaine; Chronic Disease; Diagnosis, Differential; Female; | 1979 |
Ultrastructure of motor end-plates during pharmacologically-induced degeneration and subsequent regeneration of skeletal muscle.
Topics: Animals; Bupivacaine; Cell Differentiation; Male; Mice; Microscopy, Electron; Microtubules; Motor En | 1975 |
Analysis of inflammatory cells and complement C3 in bupivacaine-induced myonecrosis.
Topics: Animals; Antibodies, Monoclonal; Bupivacaine; Complement C3; Hindlimb; Immunohistochemistry; Inflamm | 1991 |
Basement membrane component changes during experimental skeletal muscle degeneration and regeneration.
Topics: Animals; Basement Membrane; Bupivacaine; Extracellular Matrix Proteins; Male; Muscles; Muscular Dise | 1990 |
Chronic myopathy induced by repeated bupivacaine injections.
Topics: Adenosine Triphosphatases; Animals; Bupivacaine; Cholinesterases; Histocytochemistry; Male; Muscles; | 1985 |
Bupivacaine-induced muscle injury. The role of extracellular calcium.
Topics: Animals; Bupivacaine; Calcium; Calcium Channel Blockers; Creatine Kinase; Extracellular Space; Femal | 1986 |
Quantitative freeze-fracture electron-microscopic analysis of muscle plasma membrane of bupivacaine-induced myopathy.
Topics: Animals; Bupivacaine; Cell Membrane; Freeze Fracturing; Microscopy, Electron; Muscles; Muscular Dise | 1986 |
Transient quadriceps paresis following local inguinal block for postoperative pain control.
Topics: Bupivacaine; Child; Child, Preschool; Femoral Nerve; Hernia, Inguinal; Humans; Male; Muscular Diseas | 1985 |