bupivacaine has been researched along with Muscle Contraction in 78 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The relative efficacies of a long- and medium-chain triglyceride (LCT/MCT) emulsion and an LCT emulsion for treatment of bupivacaine (BPV)-induced cardiac toxicity are poorly defined." | 7.96 | Lipid Emulsion Restoration of Myocardial Contractions After Bupivacaine-Induced Asystole In Vitro: A Benefit of Long- and Medium-Chain Triglyceride Over Long-Chain Triglyceride. ( Jung, JR; Kim, HJ; Kim, HS; Kim, HY; Lynch, C; Park, WK, 2020) |
| "Significant pain reduction was achieved one hour post-bupivacaine (mean difference as a percentage change 56." | 5.10 | Effect of pain reduction on postural sway, proprioception, and quadriceps strength in subjects with knee osteoarthritis. ( Doherty, M; Doherty, SA; Hassan, BS; Mockett, S, 2002) |
| "The relative efficacies of a long- and medium-chain triglyceride (LCT/MCT) emulsion and an LCT emulsion for treatment of bupivacaine (BPV)-induced cardiac toxicity are poorly defined." | 3.96 | Lipid Emulsion Restoration of Myocardial Contractions After Bupivacaine-Induced Asystole In Vitro: A Benefit of Long- and Medium-Chain Triglyceride Over Long-Chain Triglyceride. ( Jung, JR; Kim, HJ; Kim, HS; Kim, HY; Lynch, C; Park, WK, 2020) |
| "Nitric oxide (NO) plays a key role in muscle regeneration, which is the primary response, observed during bupivacaine-induced extraocular muscle (EOM) hypertrophy." | 3.79 | The effects of bupivacaine injection and oral nitric oxide on extraocular muscle in the rabbit. ( Basmak, H; Bilgin, B; Canaz, F; Colak, E; Gursoy, H; Isiksoy, S; Ozkurt, M; Tuncel, N, 2013) |
| "These findings suggest that lidocaine and bupivacaine depress adrenergic neurotransmission and inhibit smooth muscle contraction." | 3.68 | Inhibitory effects of bupivacaine and lidocaine on adrenergic neuroeffector junctions in rat tail artery. ( Gardner, CA; Szocik, JF; Webb, RC, 1993) |
| " An in vitro study, using helical preparations of human umbilical arteries and veins obtained from healthy women at term pregnancy, was designed to determine: (a) whether three local anaesthetics commonly utilized in obstetric anaesthesia (bupivacaine, 2-chloroprocaine, and lignocaine) can induce contraction or relaxation of resting umbilical vessels; (b) whether these agents can induce contraction or relaxation of umbilical vessels which have been previously induced to contract by a known activator, potassium chloride (KCl); and (c) the relative potency of these agents as compared to KCl." | 3.67 | Vasoactive actions of local anaesthetics on human isolated umbilical veins and arteries. ( Altura, B; Freese, K; Halevy, S; Liu-Barnett, M; Monuszko, E, 1989) |
| " However, its clinical efficacy relative to bupivacaine and its dose-response characteristics, in spinal anesthesia, must first be known." | 2.70 | Hyperbaric spinal levobupivacaine: a comparison to racemic bupivacaine in volunteers. ( Alley, EA; Kopacz, DJ; Liu, SS; McDonald, SB, 2002) |
| "A randomized double-blind study was performed to elucidate the interrelationships among volume, concentration, and dosage of bupivacaine administered intrathecally." | 2.65 | A dose-response study of bupivacaine for spinal anesthesia. ( Bizzarri-Schmid, M; Covino, BG; Edstrom, H; Francis, DM; Rocco, AG; Sheskey, MC, 1983) |
| "Levobupivacaine has been developed as a safer alternative to bupivacaine because of its reduced systemic toxicity." | 1.42 | Effects of levobupivacaine on isolated rat tracheal smooth muscle. ( Chang, HC; Chen, SY; Cherng, YG; Huang, YF; Liu, FL; Wang, HW, 2015) |
| "Bupivacaine is a widely used anaesthetic injected locally in clinical practice for short-term neurotransmission blockade." | 1.38 | Acute and chronic effects of bupivacaine on muscle energetics during contraction in vivo: a modular metabolic control analysis. ( Arsac, LM; Deschodt-Arsac, V; Diolez, P; Miraux, S; Nouette-Gaulain, K; Rossignol, R; Thiaudiere, E, 2012) |
| "Levobupivacaine is a long-acting local anesthetic with a clinical profile similar to that of racemic bupivacaine but with a greater margin of safety." | 1.36 | The direct effect of levobupivacaine in isolated rat aorta involves lipoxygenase pathway activation and endothelial nitric oxide release. ( Choi, YS; Hah, YS; Hwang, EM; Jeong, YS; Lee, SH; Ok, SH; Park, JY; Shin, IW; Sohn, JT, 2010) |
| "Glycerol treatment only reduced, but did not eliminate twitches developed by muscles 7 days after injection." | 1.29 | External calcium dependence of extensor digitorum longus muscle contractility during bupivacaine-induced regeneration. ( Fichter-Gagnepain, V; Louboutin, JP; Noireaud, J, 1996) |
| "Bupivacaine is a local anesthetic commonly used in obstetrical practice." | 1.28 | Effects of bupivacaine and calcium antagonists on human uterine arteries in pregnant and non-pregnant women. ( Källfelt, B; Lindblom, B; Norén, H, 1991) |
| "Bupivacaine assays were done by gas chromatography - mass spectrometry." | 1.27 | In vivo bupivacaine reduces the in vitro sensitivity of the human vas deferens to phenylephrine. ( Kawamoto, JH; Morales, A; Nakatsu, K; Owen, JA, 1986) |
| " A short pilot study was undertaken to determine the optimal dosage and concentration of bupivacaine." | 1.25 | Intravenous regional analgesia using bupivacaine. ( Ware, RJ, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (37.18) | 18.7374 |
| 1990's | 21 (26.92) | 18.2507 |
| 2000's | 16 (20.51) | 29.6817 |
| 2010's | 11 (14.10) | 24.3611 |
| 2020's | 1 (1.28) | 2.80 |
| Authors | Studies |
|---|---|
| Kalinin, DV | 1 |
| Pantsurkin, VI | 1 |
| Syropyatov, BY | 1 |
| Kalinina, SA | 1 |
| Rudakova, IP | 1 |
| Vakhrin, MI | 1 |
| Dolzhenko, AV | 1 |
| Kim, HJ | 1 |
| Kim, HS | 1 |
| Jung, JR | 1 |
| Kim, HY | 1 |
| Lynch, C | 1 |
| Park, WK | 1 |
| Dagli, R | 1 |
| Dadali, M | 1 |
| Emir, L | 1 |
| Bagbanci, S | 1 |
| Ates, H | 1 |
| Bilgin, B | 1 |
| Gursoy, H | 1 |
| Basmak, H | 1 |
| Ozkurt, M | 1 |
| Tuncel, N | 1 |
| Canaz, F | 1 |
| Isiksoy, S | 1 |
| Colak, E | 1 |
| Patel, SI | 1 |
| Joshi, MY | 1 |
| Chang, HC | 1 |
| Chen, SY | 1 |
| Huang, YF | 1 |
| Liu, FL | 1 |
| Cherng, YG | 1 |
| Wang, HW | 1 |
| Côte, CH | 1 |
| Tremblay, MH | 1 |
| Duchesne, E | 1 |
| Lapoite, BM | 1 |
| Nader, A | 1 |
| Kendall, MC | 1 |
| Candido, KD | 1 |
| Benzon, H | 1 |
| McCarthy, RJ | 1 |
| Bruns, TM | 1 |
| Bhadra, N | 1 |
| Gustafson, KJ | 1 |
| Lagerquist, O | 1 |
| Walsh, LD | 1 |
| Blouin, JS | 1 |
| Collins, DF | 1 |
| Gandevia, SC | 1 |
| Scott, AB | 1 |
| Miller, JM | 1 |
| Shieh, KR | 1 |
| Choi, YS | 1 |
| Jeong, YS | 1 |
| Ok, SH | 1 |
| Shin, IW | 1 |
| Lee, SH | 1 |
| Park, JY | 1 |
| Hwang, EM | 1 |
| Hah, YS | 1 |
| Sohn, JT | 1 |
| Kiuchi, MG | 1 |
| Zapata-Sudo, G | 1 |
| Trachez, MM | 1 |
| Ririe, D | 1 |
| Sudo, RT | 1 |
| Altermatt, FR | 1 |
| Corvetto, MA | 1 |
| Venegas, C | 1 |
| Echevarría, G | 1 |
| Bravo, P | 1 |
| De la Cuadra, JC | 1 |
| Irribarra, LA | 1 |
| Arsac, LM | 1 |
| Nouette-Gaulain, K | 1 |
| Miraux, S | 1 |
| Deschodt-Arsac, V | 1 |
| Rossignol, R | 1 |
| Thiaudiere, E | 1 |
| Diolez, P | 1 |
| Falcão, LF | 1 |
| Perez, MV | 1 |
| de Castro, I | 1 |
| Yamashita, AM | 1 |
| Tardelli, MA | 1 |
| Amaral, JL | 1 |
| Margarido, CB | 1 |
| Dlacic, A | 1 |
| Balki, M | 1 |
| Furtado, L | 1 |
| Carvalho, JC | 1 |
| Pette, D | 1 |
| Sketelj, J | 1 |
| Skorjanc, D | 1 |
| Leisner, E | 1 |
| Traub, I | 1 |
| Bajrović, F | 1 |
| Zink, W | 1 |
| Missler, G | 1 |
| Sinner, B | 1 |
| Martin, E | 1 |
| Fink, RH | 1 |
| Graf, BM | 1 |
| Ibarra M, CA | 1 |
| Ichihara, Y | 1 |
| Hikita, M | 1 |
| Yoshida, K | 1 |
| Junji, S | 1 |
| Maehara, Y | 1 |
| Kikuchi, H | 1 |
| Kanniah, S | 1 |
| Plant, DR | 2 |
| Colarossi, FE | 1 |
| Lynch, GS | 2 |
| Oksendahl, HL | 1 |
| Fleming, BC | 1 |
| Blanpied, PR | 1 |
| Ritter, M | 1 |
| Hulstyn, MJ | 1 |
| Fadale, PD | 1 |
| Sinha, SK | 1 |
| Abrams, JH | 1 |
| Weller, RS | 1 |
| Ryall, JG | 1 |
| Schertzer, JD | 1 |
| Alabakis, TM | 1 |
| Gehrig, SM | 1 |
| Ikeda, SR | 2 |
| Aronstam, RS | 1 |
| Daly, JW | 2 |
| Aracava, Y | 2 |
| Albuquerque, EX | 2 |
| Brookes, N | 1 |
| Scurlock, JE | 1 |
| Curtis, BM | 1 |
| Gissen, AJ | 1 |
| Covino, BG | 2 |
| Gregus, J | 1 |
| Sheskey, MC | 1 |
| Rocco, AG | 1 |
| Bizzarri-Schmid, M | 1 |
| Francis, DM | 1 |
| Edstrom, H | 1 |
| Carlson, BM | 4 |
| Faulkner, JA | 3 |
| Ikai, T | 2 |
| Takagi, A | 1 |
| Yonemoto, K | 1 |
| Tuvemo, T | 1 |
| Willdeck-Lund, G | 1 |
| Hall-Craggs, EC | 1 |
| Lewis, DM | 1 |
| Schmalbruch, H | 1 |
| Wang, ZY | 1 |
| Tung, SR | 1 |
| Strichartz, GR | 1 |
| Håkanson, R | 1 |
| Chilvers, CR | 1 |
| Igawa, Y | 1 |
| Andersson, KE | 1 |
| Post, C | 1 |
| Uvelius, B | 1 |
| Mattiasson, A | 1 |
| Takahashi, M | 1 |
| Miyamura, H | 1 |
| Eguchi, S | 1 |
| Homma, S | 1 |
| Szocik, JF | 1 |
| Gardner, CA | 1 |
| Webb, RC | 1 |
| Sharrock, NE | 1 |
| Hotchkiss, R | 1 |
| Ennis, WJ | 1 |
| Weiland, A | 1 |
| Louboutin, JP | 2 |
| Fichter-Gagnepain, V | 1 |
| Noireaud, J | 2 |
| Häkkinen, V | 1 |
| Eskola, H | 1 |
| Yli-Hankala, A | 1 |
| Nurmikko, T | 1 |
| Kolehmainen, S | 1 |
| Tamaki, T | 1 |
| Akatsuka, A | 1 |
| Uchiyama, S | 1 |
| Uchiyama, Y | 1 |
| Shiraishi, T | 1 |
| Nosaka, K | 1 |
| Sakamoto, K | 1 |
| Oh, SJ | 1 |
| Kim, SJ | 1 |
| Park, EC | 1 |
| Chung, HK | 1 |
| Kim, KW | 1 |
| Choi, H | 1 |
| Alley, EA | 1 |
| Kopacz, DJ | 1 |
| McDonald, SB | 1 |
| Liu, SS | 1 |
| Hassan, BS | 1 |
| Doherty, SA | 1 |
| Mockett, S | 1 |
| Doherty, M | 1 |
| Downes, H | 1 |
| Loehning, RW | 1 |
| Torrens, MJ | 1 |
| Griffith, HB | 1 |
| Gutmann, E | 1 |
| Sjövall, B | 1 |
| Radtke, H | 1 |
| Nolte, H | 3 |
| Fruhstorfer, H | 2 |
| Zenz, M | 2 |
| Phillips, G | 1 |
| Wencker, KH | 1 |
| Ware, RJ | 1 |
| Blunt, RJ | 1 |
| Vrbová, G | 1 |
| Rosenblatt, JD | 1 |
| Woods, RI | 1 |
| McInerney, PD | 1 |
| Grant, A | 1 |
| Chawla, J | 1 |
| Stephenson, TP | 1 |
| Norén, H | 1 |
| Lindblom, B | 1 |
| Källfelt, B | 1 |
| Kimura, M | 2 |
| Kimura, I | 2 |
| Kondoh, T | 2 |
| Tsuneki, H | 2 |
| Toft, P | 1 |
| Kirkegaard Nielsen, H | 1 |
| Severinsen, I | 1 |
| Helbo-Hansen, HS | 1 |
| Penning, JP | 1 |
| Nagasaka, H | 1 |
| Yaksh, TL | 1 |
| Monuszko, E | 1 |
| Halevy, S | 1 |
| Freese, K | 1 |
| Liu-Barnett, M | 1 |
| Altura, B | 1 |
| Nosaka, S | 1 |
| Kamaya, H | 1 |
| Ueda, I | 1 |
| Wong, KC | 1 |
| Ulrich, C | 1 |
| Burri, C | 1 |
| Wörsdörfer, O | 1 |
| Hoffmann, P | 1 |
| Thorén, P | 1 |
| Kawamoto, JH | 1 |
| Owen, JA | 1 |
| Morales, A | 1 |
| Nakatsu, K | 1 |
| Axelsson, K | 1 |
| Hallgren, S | 1 |
| Widman, B | 1 |
| Johansson, A | 1 |
| Olstrin, PO | 1 |
| Meyer, J | 1 |
| Köpf, B | 1 |
| Aberg, G | 1 |
| Wahlström, B | 1 |
| Jenssen, H | 1 |
| Chapman, GM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Bupivacaine Injection of Eye Muscles to Treat Strabismus[NCT01616108] | Phase 2/Phase 3 | 120 participants (Anticipated) | Interventional | 2012-04-30 | Recruiting | ||
| Determination of the Minimum Effective Volume of Local Anesthetic Using Ultrasound Guidance for Interscalene Brachial Plexus Block[NCT01244932] | Phase 2 | 33 participants (Anticipated) | Interventional | 2009-09-30 | Completed | ||
| Evaluation of Variation of Ventilation and Pulmonary Aeration Using Electrical Impedance Tomography in Patients With Interscalene Brachial Plexus Block for Shoulder Surgery[NCT03577860] | 40 participants (Anticipated) | Interventional | 2018-05-17 | Recruiting | |||
| Comparison of the Efficacy of 0.5% Bupivacaine, 0.5% Levobupivacaine, and 0.5% Hyperbaric Bupivacaine in Equal Volumes for Spinal Anesthesia in Lower Limb Surgeries[NCT05184465] | 111 participants (Actual) | Interventional | 2017-12-18 | Completed | |||
| Is There a Difference in the Analgesic Response to Intra-articular Bupivacaine Injection in People With Knee Osteoarthritis Pain With or Without Central Sensitisation?: a Feasibility Randomised Controlled Trial[NCT05561010] | 50 participants (Anticipated) | Interventional | 2022-10-31 | Not yet recruiting | |||
| Effect of Intravenous Infusion of Magnesium Sulfate Associated or Not to Lidocaine On the Neuromuscular Blockade Induced by Muscle Relaxant Cistracurium[NCT02483611] | Phase 4 | 48 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"The clinical duration is the elapsed time for T1 recovery = 25% (Dur25%) of the original value of T1 after the infusion of cisatracurium.~This outcome meansure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes
| Intervention | minutes (Median) |
|---|---|
| Group M | 82.68 |
| Group ML | 86.33 |
| Group C | 64.8 |
"The final recovery index is the elapsed time between the T1 recovery = 25% (Dur25%) and T4 / T1 = 80% (TOF = 80%) after the infusion of cisatracurium.~This outcome measure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes
| Intervention | minutes (Mean) |
|---|---|
| Group M | 27.97 |
| Group ML | 33.81 |
| Group C | 21.51 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The measure of heart rate was recorded and annotated at various times such as in the arrival of the patient in the operating room. This time point was named as moment '1'. (NCT02483611)
Timeframe: This measure of heart rate was performed when the patient arrived in the operating room
| Intervention | beats/min (Mean) |
|---|---|
| Group M | 79.94 |
| Group ML | 77.25 |
| Group C | 73.66 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as in the moment immediately before the anesthesia induction. This time point was named as moment '2'. (NCT02483611)
Timeframe: This measure of heart rate was performed immediately before induction of anesthesia
| Intervention | beats/min (Mean) |
|---|---|
| Group M | 74.69 |
| Group ML | 73.69 |
| Group C | 75.40 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution). This time point was named as moment '3'. (NCT02483611)
Timeframe: This measure of heart rate was performed immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution)
| Intervention | beats/min (Mean) |
|---|---|
| Group M | 72.94 |
| Group ML | 74.19 |
| Group C | 75.40 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as in the end of the study solutions infusion. This time point was named as moment '4'. (NCT02483611)
Timeframe: This measure of heart rate was performed five minutes after M3 (in the end of the X and Y solutions infusion)
| Intervention | beats/min (Mean) |
|---|---|
| Group M | 71.94 |
| Group ML | 72.25 |
| Group C | 65.07 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as immediately before the tracheal intubation. This time point was named as moment '5'. (NCT02483611)
Timeframe: This measure of heart rate was performed immediately before the tracheal intubation
| Intervention | beats/min (Mean) |
|---|---|
| Group M | 67.56 |
| Group ML | 69.31 |
| Group C | 64.27 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as one minute after the tracheal intubation. This time point was named as moment '6'. (NCT02483611)
Timeframe: This measure of heart rate was performed one minute after the tracheal intubation
| Intervention | beats/min (Mean) |
|---|---|
| Group M | 66.50 |
| Group ML | 68.19 |
| Group C | 65.13 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 15 minutes after the traqueal intubation.This time point was named as moment '7a'. (NCT02483611)
Timeframe: This measure of heart rate was performed 15 minutes after the traqueal intubation
| Intervention | beats/min (Mean) |
|---|---|
| Group M | 68.94 |
| Group ML | 68.19 |
| Group C | 67.13 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 30 minutes after the traqueal intubation. This time point was named as moment '7b'. (NCT02483611)
Timeframe: This measure of heart rate was performed 30 minutes after the traqueal intubation
| Intervention | beats/min (Mean) |
|---|---|
| Group M | 67.44 |
| Group ML | 68.38 |
| Group C | 64.00 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 45 minutes after the traqueal intubation. This time point was named as moment '7c'. (NCT02483611)
Timeframe: This measure of heart rate was performed 45 minutes after the traqueal intubation
| Intervention | beats/min (Mean) |
|---|---|
| Group M | 65.75 |
| Group ML | 65.75 |
| Group C | 62.33 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 60 minutes after the traqueal intubation. This time point was named as moment '7d'. (NCT02483611)
Timeframe: This measure of heart rate was performed 60 minutes after the traqueal intubation
| Intervention | beats/min (Mean) |
|---|---|
| Group M | 66.19 |
| Group ML | 65.31 |
| Group C | 61.93 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 75 minutes after the traqueal intubation. This time point was named as moment '7e'. (NCT02483611)
Timeframe: This measure of heart rate was performed 75 minutes after the traqueal intubation
| Intervention | beats/min (Median) |
|---|---|
| Group M | 66.50 |
| Group ML | 63.00 |
| Group C | 58.00 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 90 minutes after the traqueal intubation. This time point was named as moment '7f'. (NCT02483611)
Timeframe: This measure of heart rate was performed 90 minutes after the traqueal intubation
| Intervention | beats/min (Median) |
|---|---|
| Group M | 66.00 |
| Group ML | 61.00 |
| Group C | 61.00 |
"The latency is computed as the elapsed time to reduce the response of T1 to 5% of the initial contraction force after the infusion of cisatracurium.~This outcome meansure was presented in seconds." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes
| Intervention | seconds (Mean) |
|---|---|
| Group M | 139.70 |
| Group ML | 151.30 |
| Group C | 147.80 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as in the arrival of the patient in the operating room. This time point was named as moment '1'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed when the patient arrived in the operating room
| Intervention | mmHg (Mean) |
|---|---|
| Group M | 94.63 |
| Group ML | 88.75 |
| Group C | 100.10 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as in the moment immediately before the anesthesia induction. This time point was named as moment '2'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed immediately before induction of anesthesia
| Intervention | mmHg (Mean) |
|---|---|
| Group M | 87.63 |
| Group ML | 84.69 |
| Group C | 92.47 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution). This time point was named as moment '3'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution)
| Intervention | mmHg (Mean) |
|---|---|
| Group M | 75.88 |
| Group ML | 73.88 |
| Group C | 76.73 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as in the end of the study solutions infusion.This time point was named as moment '4'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed five minutes after M3 (in the end of the X and Y solutions infusion)
| Intervention | mmHg (Median) |
|---|---|
| Group M | 69.00 |
| Group ML | 63.00 |
| Group C | 74.00 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as immediately before the tracheal intubation. This time point was named as moment '5'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed immediately before the tracheal intubation
| Intervention | mmHg (Median) |
|---|---|
| Group M | 62.50 |
| Group ML | 61.50 |
| Group C | 67.00 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as one minute after the tracheal intubation. This time point was named as moment '6'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed one minute after the tracheal intubation
| Intervention | mmHg (Median) |
|---|---|
| Group M | 64.50 |
| Group ML | 64.00 |
| Group C | 69.00 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 15 minutes after the traqueal intubation. This time point was named as moment '7a'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 15 minutes after the traqueal intubation
| Intervention | mmHg (Median) |
|---|---|
| Group M | 66.00 |
| Group ML | 61.50 |
| Group C | 69.00 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 30 minutes after the traqueal intubation. This time point was named as moment '7b'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 30 minutes after the traqueal intubation
| Intervention | mmHg (Median) |
|---|---|
| Group M | 66.50 |
| Group ML | 63.50 |
| Group C | 68.00 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 45 minutes after the traqueal intubation. This time point was named as moment '7c'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 45 minutes after the traqueal intubation
| Intervention | mmHg (Mean) |
|---|---|
| Group M | 69.25 |
| Group ML | 63.00 |
| Group C | 69.00 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 60 minutes after the traqueal intubation. This time point was named as moment '7d'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 60 minutes after the traqueal intubation
| Intervention | mmHg (Median) |
|---|---|
| Group M | 68.00 |
| Group ML | 62.00 |
| Group C | 66.00 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 75 minutes after the traqueal intubation. This time point was named as moment '7e'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 75 minutes after the traqueal intubation
| Intervention | mmHg (Median) |
|---|---|
| Group M | 68.00 |
| Group ML | 66.00 |
| Group C | 69.00 |
In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 90 minutes after the traqueal intubation. This time point was named as moment '7f'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 90 minutes after the traqueal intubation
| Intervention | mmHg (Median) |
|---|---|
| Group M | 64.00 |
| Group ML | 64.50 |
| Group C | 72.00 |
"The recovery index is the elapsed time between the T1 recovery =25% (Dur25%) and T1 =75% (Dur75%) after the infusion of cisatracurium.~This outcome meansure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes
| Intervention | minutes (Mean) |
|---|---|
| Group M | 20.08 |
| Group ML | 20.26 |
| Group C | 14.53 |
"Spontaneous recovery is the elapsed time for the recovery of the TOF (T4 / T1) response to 90% of the original after infusion of cisatracurium.~This outcome measure was presented in minutes." (NCT02483611)
Timeframe: The participants were followed during the anesthetic - surgical procedure
| Intervention | minutes (Mean) |
|---|---|
| Group M | 120.20 |
| Group ML | 126.70 |
| Group C | 90.03 |
"The total duration is the elapsed time for T1 recovery of the response to reach 95% of the initial after the infusion of cisatracurium.~This outcome measure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes
| Intervention | minutes (Mean) |
|---|---|
| Group M | 113.20 |
| Group ML | 120.10 |
| Group C | 88.19 |
1 review available for bupivacaine and Muscle Contraction
| Article | Year |
|---|---|
The regeneration of skeletal muscle fibers following injury: a review.
Topics: Anesthetics, Local; Animals; Athletic Injuries; Bupivacaine; Cats; Humans; Ischemia; Muscle Contract | 1983 |
13 trials available for bupivacaine and Muscle Contraction
| Article | Year |
|---|---|
Comparison of Classic and Inguinal Obturator Nerve Blocks Applied for Preventing Adductor Muscle Contractions in Bladder Tumor Surgeries: A Prospective Randomized Trial.
Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Groin; Humans; Male; Midd | 2019 |
A randomized comparison of a modified intertendinous and classic posterior approach to popliteal sciatic nerve block.
Topics: Adult; Anesthetics, Local; Bupivacaine; Electric Stimulation; Female; Foot; Humans; Injections; Levo | 2009 |
Bupivacaine injection of the lateral rectus muscle to treat esotropia.
Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Esotropia; Humans; Injections, Intramuscular; Magnetic | 2009 |
Minimum effective volume of 0.5% bupivacaine with epinephrine in ultrasound-guided interscalene brachial plexus block.
Topics: Adult; Aged; Anesthetics, Local; Brachial Plexus; Bupivacaine; Epinephrine; Female; Humans; Male; Mi | 2013 |
Ultrasound-guided interscalene needle placement produces successful anesthesia regardless of motor stimulation above or below 0.5 mA.
Topics: Adult; Ambulatory Surgical Procedures; Anesthetics, Local; Brachial Plexus; Bupivacaine; Electric St | 2007 |
A dose-response study of bupivacaine for spinal anesthesia.
Topics: Adult; Aged; Anesthesia, Spinal; Bupivacaine; Clinical Trials as Topic; Dose-Response Relationship, | 1983 |
Warm local anaesthetic--effect on latency of onset of axillary brachial plexus block.
Topics: Adult; Axilla; Body Temperature; Brachial Plexus; Bupivacaine; Double-Blind Method; Epinephrine; Fem | 1993 |
Hyperbaric spinal levobupivacaine: a comparison to racemic bupivacaine in volunteers.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cross-Over Studies; Dose-Response Relati | 2002 |
Effect of pain reduction on postural sway, proprioception, and quadriceps strength in subjects with knee osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Bupivacaine; Cross-Over Studies; Double-Blind Method; El | 2002 |
A comparative study between etidocaine and bupivacaine in ulnar nerve block.
Topics: Acetanilides; Action Potentials; Adult; Autonomic Nerve Block; Bupivacaine; Clinical Trials as Topic | 1975 |
A double-blind trial of bupivacaine and etidocaine in epidural block for surgical induction of labour.
Topics: Acetanilides; Anesthesia, Epidural; Anesthesia, Obstetrical; Blood Pressure; Bupivacaine; Clinical T | 1975 |
Effect of epidurally administered bupivacaine on atracurium-induced neuromuscular blockade.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Epidural; Anesthesia, Intravenous; Atracurium; Blood | 1990 |
[Clinical and electrophysiological parameters for the differentiation of actions of local anaesthetics (author's transl)].
Topics: Action Potentials; Analgesia; Anesthetics, Local; Autonomic Nervous System; Body Temperature; Bupiva | 1974 |
64 other studies available for bupivacaine and Muscle Contraction
| Article | Year |
|---|---|
Synthesis, local anaesthetic and antiarrhythmic activities of N-alkyl derivatives of proline anilides.
Topics: Alkanes; Amides; Anesthetics, Local; Anilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac | 2013 |
Lipid Emulsion Restoration of Myocardial Contractions After Bupivacaine-Induced Asystole In Vitro: A Benefit of Long- and Medium-Chain Triglyceride Over Long-Chain Triglyceride.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiotoxicity; Drug Compounding; Energy Metabolism; Fat E | 2020 |
The effects of bupivacaine injection and oral nitric oxide on extraocular muscle in the rabbit.
Topics: Administration, Oral; Anesthetics, Local; Animals; Bupivacaine; Hypertrophy; Injections, Intramuscul | 2013 |
Neurostimulation with ultrasound guidance for intercostal nerve block.
Topics: Bupivacaine; Electric Stimulation; Glucocorticoids; Humans; Intercostal Nerves; Male; Middle Aged; M | 2013 |
Effects of levobupivacaine on isolated rat tracheal smooth muscle.
Topics: Animals; Bupivacaine; Electric Stimulation; Levobupivacaine; Methacholine Chloride; Muscle Contracti | 2015 |
Inflammation-induced leukocyte accumulation in injured skeletal muscle: role of mast cells.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cell Degranulation; Cytoplasmic Granules; Immunohistochemi | 2008 |
Intraurethral stimulation for reflex bladder activation depends on stimulation pattern and location.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cats; Electric Stimulation; Male; Muscle Contraction; Musc | 2009 |
Effect of a peripheral nerve block on torque produced by repetitive electrical stimulation.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Drug Combinations; Electric Stimulation; | 2009 |
The direct effect of levobupivacaine in isolated rat aorta involves lipoxygenase pathway activation and endothelial nitric oxide release.
Topics: Anesthetics, Local; Animals; Aorta, Thoracic; Benzoquinones; Bupivacaine; Calcium; Dose-Response Rel | 2010 |
The influence of age on bupivacaine cardiotoxicity.
Topics: Age Factors; Animals; Animals, Newborn; Bupivacaine; Calcium; Cardiotoxins; Dose-Response Relationsh | 2011 |
Brief report: The sensitivity of motor responses for detecting catheter-nerve contact during ultrasound-guided femoral nerve blocks with stimulating catheters.
Topics: Adult; Anesthetics, Local; Bupivacaine; Catheterization; Catheters; Electric Stimulation; Female; Fe | 2011 |
Acute and chronic effects of bupivacaine on muscle energetics during contraction in vivo: a modular metabolic control analysis.
Topics: Animals; Bupivacaine; Energy Metabolism; Female; Muscle Contraction; Muscle, Skeletal; Rats; Rats, W | 2012 |
The epidural electric stimulation test does not predict local anesthetic spread or consumption in labour epidural analgesia.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Anesthetics, Loca | 2013 |
Partial fast-to-slow conversion of regenerating rat fast-twitch muscle by chronic low-frequency stimulation.
Topics: Animals; Bupivacaine; Cell Death; Electric Stimulation; Male; Muscle Contraction; Muscle Fibers, Fas | 2002 |
Differential effects of bupivacaine and ropivacaine enantiomers on intracellular Ca2+ regulation in murine skeletal muscle fibers.
Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Caffeine; Calcium; Calcium Signaling; Central Nerv | 2005 |
Effect of bupivacaine enantiomers on Ca2+ release from sarcoplasmic reticulum in skeletal muscle.
Topics: Animals; Bupivacaine; Calcium; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; M | 2005 |
Anesthesia for Cesarean delivery in a parturient with rigid spine syndrome.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesth | 2006 |
Notexin causes greater myotoxic damage and slower functional repair in mouse skeletal muscles than bupivacaine.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cell Death; Cytotoxins; Disease Models, Animal; Elapid Ven | 2006 |
Intra-articular anesthesia and knee muscle response.
Topics: Adolescent; Adult; Anesthetics, Local; Bupivacaine; Female; Humans; Injections, Intra-Articular; Kne | 2007 |
Intramuscular beta2-agonist administration enhances early regeneration and functional repair in rat skeletal muscle after myotoxic injury.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Anesthetics, Local; Animals; Blotting | 2008 |
Interactions of bupivacaine with ionic channels of the nicotinic receptor. Electrophysiological and biochemical studies.
Topics: Animals; Bupivacaine; Electric Conductivity; Ion Channels; Membrane Potentials; Motor Endplate; Musc | 1984 |
Interactions of bupivacaine with ionic channels of the nicotinic receptor. Analysis of single-channel currents.
Topics: Acetylcholine; Animals; Animals, Newborn; Bupivacaine; Cells, Cultured; Ion Channels; Membrane Poten | 1984 |
Dextran-local anesthetic interactions.
Topics: Action Potentials; Anesthetics, Local; Animals; Anura; Bupivacaine; Dextrans; Dialysis; Drug Interac | 1980 |
Differential sensitivity of fast and slow fibers in mammalian nerve. III. Effect of etidocaine and bupivacaine on fast/slow fibers.
Topics: Acetanilides; Action Potentials; Animals; Bupivacaine; Etidocaine; In Vitro Techniques; Muscle Contr | 1982 |
[The influence of Marcaine on the function of the sarcoplasmic reticulum].
Topics: Anesthetics, Local; Animals; Bupivacaine; Calcium; In Vitro Techniques; Male; Muscle Contraction; Ra | 1984 |
Smooth muscle effects of lidocaine, prilocaine, bupivacaine and etiodocaine on the human umbilical artery.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Bupivacaine; Dose-Response Relati | 1982 |
Early ultrastructural changes in skeletal muscle exposed to the local anaesthetic bupivacaine (Marcaine).
Topics: Animals; Bupivacaine; Cell Membrane; Cell Nucleus; Connective Tissue; Female; Microscopy, Electron; | 1980 |
Contractile properties of aneurally regenerated compared with denervated muscles of rat.
Topics: Animals; Bupivacaine; Isometric Contraction; Male; Muscle Contraction; Muscle Denervation; Muscle, S | 1994 |
Non-specific actions of the non-peptide tachykinin receptor antagonists, CP-96,345, RP 67580 and SR 48968, on neurotransmission.
Topics: Action Potentials; Anesthetics, Local; Animals; Benzamides; Biphenyl Compounds; Bupivacaine; Electri | 1994 |
A rat model for investigation of spinal mechanisms in detrusor instability associated with infravesical outflow obstruction.
Topics: Animals; Bupivacaine; Disease Models, Animal; Female; Hypertrophy; Injections, Spinal; Morphine; Mus | 1993 |
The effect of bupivacaine hydrochloride on skeletal muscle fiber type transformation by low frequency electrical stimulation.
Topics: Animals; Biomarkers; Bupivacaine; Cell Differentiation; Electric Stimulation; Male; Muscle Contracti | 1993 |
Inhibitory effects of bupivacaine and lidocaine on adrenergic neuroeffector junctions in rat tail artery.
Topics: Animals; Arteries; Bupivacaine; Dose-Response Relationship, Drug; Electric Stimulation; Lidocaine; M | 1993 |
The regeneration of noninnervated muscle grafts and marcaine-treated muscles in young and old rats.
Topics: Aging; Animals; Bupivacaine; Male; Muscle Contraction; Muscles; Rats; Rats, Inbred F344; Regeneratio | 1996 |
Brachial plexus surgery through the infraclavicular approach using an interscalene block.
Topics: Adult; Arm; Brachial Plexus; Bupivacaine; Clavicle; Electric Stimulation; Female; Humans; Mepivacain | 1996 |
External calcium dependence of extensor digitorum longus muscle contractility during bupivacaine-induced regeneration.
Topics: Animals; Bupivacaine; Caffeine; Calcium; Glycerol; Male; Muscle Contraction; Muscles; Rats; Rats, Wi | 1996 |
Which structures are sensitive to painful transcranial electric stimulation?
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Drug Combinations; Electric Stimulation; | 1995 |
Muscle regeneration in young and old rats: effects of motor nerve transection with and without marcaine treatment.
Topics: Aging; Analysis of Variance; Anesthetics, Local; Animals; Axons; Bupivacaine; Linear Models; Male; M | 1998 |
Appearance of complex branched muscle fibers is associated with a shift to slow muscle characteristics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Hindlimb; Histocytochemistry; Male; Microscopy, Electron, | 1997 |
Sodium withdrawal contractures in developing and regenerating rat extensor digitorum longus muscles.
Topics: Anesthetics, Local; Animals; Bupivacaine; Calcium; Contracture; Male; Muscle Contraction; Muscle Dev | 1998 |
Changes in plasma enzyme activity after intramuscular injection of bupivacaine into the human biceps brachii.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Bupivacaine; Creatine Kinase; Humans; Inje | 1999 |
Effects of local anesthetics on the contractility of rat bladders.
Topics: Anesthetics, Local; Animals; Bupivacaine; Carbachol; Cholinergic Agonists; Female; Lidocaine; Male; | 2001 |
Local anesthetic contracture and relaxation of airway smooth muscle.
Topics: Aminobenzoates; Anesthetics, Local; Animals; Bronchodilator Agents; Bupivacaine; Carbachol; Guinea P | 1977 |
Management of the uninhibited bladder by selective sacral neurectomy.
Topics: Anesthesia, Caudal; Anesthesia, Local; Bupivacaine; Denervation; Enuresis; Female; Gastrointestinal | 1976 |
Free grafting of the extensor digitorum longus muscle in the rat after marcaine pretreatment.
Topics: Animals; Bupivacaine; Evoked Potentials; Male; Models, Biological; Muscle Contraction; Muscle Denerv | 1976 |
The effect of some local anaesthetics upon the electrical and mechanical activity of respiratory muscles in cats during pentobarbital anaesthesia.
Topics: Anesthetics, Local; Animals; Bupivacaine; Carbon Dioxide; Cats; Depression, Chemical; Diaphragm; Fem | 1975 |
Brachial plexus blockade for evaluation of local anaesthetic agents.
Topics: Action Potentials; Adult; Analgesia; Anesthetics, Local; Brachial Plexus; Bupivacaine; Epinephrine; | 1975 |
Intravenous regional analgesia using bupivacaine.
Topics: Adolescent; Anesthesia, Conduction; Anesthesia, Intravenous; Arm; Body Weight; Bupivacaine; Female; | 1975 |
The use of local anaesthetics to produce prolonged motor nerve block in the study of denervation hypersensitivity.
Topics: Acetylcholine; Animals; Bupivacaine; Hindlimb; Lidocaine; Muscle Contraction; Muscles; Myelin Sheath | 1975 |
Hypertrophy of rat extensor digitorum longus muscle injected with bupivacaine. A sequential histochemical, immunohistochemical, histological and morphometric study.
Topics: Animals; Bupivacaine; Histocytochemistry; Hypertrophy; Immunohistochemistry; Male; Muscle Contractio | 1992 |
The effect of intravesical Marcain instillation on hyperreflexic detrusor contractions.
Topics: Administration, Intravesical; Adolescent; Adult; Aged; Anesthesia, Local; Bupivacaine; Female; Human | 1992 |
Effects of bupivacaine and calcium antagonists on human uterine arteries in pregnant and non-pregnant women.
Topics: Arteries; Bupivacaine; Female; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vasc | 1991 |
Noncontractile acetylcholine receptor-operated Ca++ mobilization: suppression of activation by open channel blockers and acceleration of desensitization by closed channel blockers in mouse diaphragm muscle.
Topics: Aequorin; Animals; Anti-Ulcer Agents; Bupivacaine; Calcium; Calcium Channel Blockers; Chlorpromazine | 1991 |
Enhancing effect by nicotinic acetylcholine receptor channel blockers, including beta-eudesmol, on succinylcholine-induced inhibition of twitch tension and intracellular Ca++ in mouse diaphragm muscle.
Topics: Aequorin; Animals; Bupivacaine; Calcium; Chlorpromazine; Diaphragm; Dose-Response Relationship, Drug | 1991 |
Intrathecal morphine and bupivacaine in the rat; analgesic synergy without augmentation of motor dysfunction or hypotension.
Topics: Animals; Blood Pressure; Bupivacaine; Dose-Response Relationship, Drug; Drug Synergism; Heart Rate; | 1990 |
Vasoactive actions of local anaesthetics on human isolated umbilical veins and arteries.
Topics: Anesthetics, Local; Bupivacaine; Female; Humans; In Vitro Techniques; Lidocaine; Muscle Contraction; | 1989 |
Smooth muscle contraction and local anesthetics: calmodulin-dependent myosin light-chain kinase.
Topics: Bupivacaine; Calcium; Calmodulin; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide | 1989 |
[Postoperative knee joint mobilization in catheter peridural anesthesia following arthrolyses of the knee joint].
Topics: Adolescent; Adult; Aged; Anesthesia, Epidural; Arthritis, Infectious; Bupivacaine; Catheterization; | 1985 |
Electric muscle stimulation in the hind leg of the spontaneously hypertensive rat induces a long-lasting fall in blood pressure.
Topics: Afferent Pathways; Animals; Blood Pressure; Bupivacaine; Electric Stimulation; Fenclonine; Heart Rat | 1988 |
[An experimental study on acute rhabdomyolysis in vitro--the influence of a local anesthetic on whole muscle and single muscle fiber function].
Topics: Acute Disease; Anesthetics, Local; Animals; Bupivacaine; Calcium; Creatine Kinase; In Vitro Techniqu | 1986 |
In vivo bupivacaine reduces the in vitro sensitivity of the human vas deferens to phenylephrine.
Topics: Bupivacaine; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Kinetics; Male; Musc | 1986 |
A new method for measuring motor block in the lower extremities.
Topics: Aged; Anesthesia, Spinal; Bupivacaine; Humans; Isometric Contraction; Leg; Male; Middle Aged; Muscle | 1985 |
Mechanical and electrophysiological effects of some local anaesthetic agents and their isomers on the rat portal vein.
Topics: Action Potentials; Anesthetics, Local; Animals; Bupivacaine; In Vitro Techniques; Isomerism; Male; M | 1972 |
The effect of paracervical block on cervical dilatation and uterine activity.
Topics: Adult; Amnion; Anesthesia, Obstetrical; Apgar Score; Autonomic Nerve Block; Birth Weight; Bupivacain | 1973 |
Regional nerve block with the aid of a nerve stimulator.
Topics: Anesthesia, Conduction; Bupivacaine; Electric Stimulation; Humans; Lidocaine; Methods; Muscle Contra | 1972 |