bupivacaine has been researched along with Malignant Melanoma in 9 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human colon cancer cells and human melanoma cells were cultured and then treated with 1 mM bupivacaine or levobupivacaine for up to 24 or 48 h." | 7.91 | Both Bupivacaine and Levobupivacaine inhibit colon cancer cell growth but not melanoma cells in vitro. ( Chen, L; Han, C; Hirota, K; Li, T; Ma, D; Masters, J; Wu, L; Zhao, H, 2019) |
| "The effect of hyperthermia and bupivacaine, alone and in combination, on the clonogenic activity of a human melanoma cell line was investigated." | 7.70 | Thermal behavior of human melanoma cell line in vitro and enhancement of hyperthermic response by bupivacaine. ( Antonucci, E; Bruno, T; Di Padova, M; Dolo, V; Floridi, A; Gentile, FP; Pavan, A; Rubiu, O, 1998) |
| "To test whether prophylactic neural blockade of noziceptive afferents or antiemetics diminutes postoperative nausea and vomiting (PONV) we studied in a randomised, prospective, and ouble-blind fashion 102 patients receiving implantation of an episcleral radioactive applicator for treatment of ocular malignant melanoma during remifentanil-propofol-anaesthesia." | 5.10 | [Blocking nociceptive afferents by retrobulbar bupivacaine does not decrease nausea and vomiting after propofol-remifentanil anaesthesia]. ( Apfel, CC; Armbruster, W; Bornfeld, N; Müller, D; Peters, J; Unkel, W, 2003) |
| "Ropivacaine and lidocaine but not bupivacaine inhibited migration and proliferation, and induced apoptosis in melanoma cells." | 3.96 | Cytotoxicity of amide-linked local anesthetics on melanoma cells via inhibition of Ras and RhoA signaling independent of sodium channel blockade. ( Peng, X; Zhang, Y; Zheng, Q, 2020) |
| "Human colon cancer cells and human melanoma cells were cultured and then treated with 1 mM bupivacaine or levobupivacaine for up to 24 or 48 h." | 3.91 | Both Bupivacaine and Levobupivacaine inhibit colon cancer cell growth but not melanoma cells in vitro. ( Chen, L; Han, C; Hirota, K; Li, T; Ma, D; Masters, J; Wu, L; Zhao, H, 2019) |
| "The effect of hyperthermia and bupivacaine, alone and in combination, on the clonogenic activity of a human melanoma cell line was investigated." | 3.70 | Thermal behavior of human melanoma cell line in vitro and enhancement of hyperthermic response by bupivacaine. ( Antonucci, E; Bruno, T; Di Padova, M; Dolo, V; Floridi, A; Gentile, FP; Pavan, A; Rubiu, O, 1998) |
| "Up to 90% of patients with advanced cancer experience intractable pain." | 2.50 | Treatment of medically refractory cancer pain with a combination of intrathecal neuromodulation and neurosurgical ablation: case series and literature review. ( Bentley, JN; Patil, PG; Rosenberg, WS; Viswanathan, A, 2014) |
| "Bupivacaine was more potent than lidocaine both on the glycolytic enzymes and on cell viability." | 1.31 | Detachment of the glycolytic enzymes, phosphofructokinase and aldolase, from cytoskeleton of melanoma cells, induced by local anesthetics. ( Beitner, R; Schwartz, D, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, Q | 1 |
| Peng, X | 1 |
| Zhang, Y | 1 |
| Li, T | 1 |
| Chen, L | 1 |
| Zhao, H | 1 |
| Wu, L | 1 |
| Masters, J | 1 |
| Han, C | 1 |
| Hirota, K | 1 |
| Ma, D | 1 |
| Bentley, JN | 1 |
| Viswanathan, A | 1 |
| Rosenberg, WS | 1 |
| Patil, PG | 1 |
| Müller, D | 1 |
| Armbruster, W | 1 |
| Unkel, W | 1 |
| Apfel, CC | 1 |
| Bornfeld, N | 1 |
| Peters, J | 1 |
| Bowyer, J | 1 |
| Jones, A | 1 |
| Damato, B | 1 |
| Leach, A | 1 |
| Shankar, J | 1 |
| Tripathi, A | 1 |
| Holmfred, A | 1 |
| Jastrzebski, T | 1 |
| Sommer, A | 1 |
| Swierblewski, M | 1 |
| Lass, P | 1 |
| Rogowski, J | 1 |
| Drucis, K | 1 |
| Kopacz, A | 1 |
| Bruno, T | 1 |
| Gentile, FP | 1 |
| Di Padova, M | 1 |
| Antonucci, E | 1 |
| Rubiu, O | 1 |
| Dolo, V | 1 |
| Pavan, A | 1 |
| Floridi, A | 1 |
| Schwartz, D | 1 |
| Beitner, R | 1 |
1 review available for bupivacaine and Malignant Melanoma
| Article | Year |
|---|---|
Treatment of medically refractory cancer pain with a combination of intrathecal neuromodulation and neurosurgical ablation: case series and literature review.
Topics: Adolescent; Aged; Bone Neoplasms; Bupivacaine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell | 2014 |
1 trial available for bupivacaine and Malignant Melanoma
| Article | Year |
|---|---|
[Blocking nociceptive afferents by retrobulbar bupivacaine does not decrease nausea and vomiting after propofol-remifentanil anaesthesia].
Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Double-Bli | 2003 |
7 other studies available for bupivacaine and Malignant Melanoma
| Article | Year |
|---|---|
Cytotoxicity of amide-linked local anesthetics on melanoma cells via inhibition of Ras and RhoA signaling independent of sodium channel blockade.
Topics: Anesthetics, Local; Bupivacaine; Cell Death; Cell Line, Tumor; Humans; In Vitro Techniques; Lidocain | 2020 |
Both Bupivacaine and Levobupivacaine inhibit colon cancer cell growth but not melanoma cells in vitro.
Topics: Anesthetics, Local; Apoptosis; Bupivacaine; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; | 2019 |
The subjective experience of early postoperative pain following retrobulbar anaesthesia for enucleation and primary orbital implant.
Topics: Adult; Aged; Aged, 80 and over; Bupivacaine; Female; Humans; Male; Melanoma; Middle Aged; Nerve Bloc | 2003 |
Failed intrathecal analgesia following severe, terminal cancer pain.
Topics: Amines; Analgesics; Anesthetics, Local; Back Pain; Bupivacaine; Catheterization; Clonidine; Cyclohex | 2004 |
Possibilities of improving the parameters of hyperthermia in regional isolated limb perfusion using epidural bupivacaine and accurate temperature measurement of the three layers of limb tissue.
Topics: Adult; Aged; Bupivacaine; Chemotherapy, Cancer, Regional Perfusion; Combined Modality Therapy; Femal | 2006 |
Thermal behavior of human melanoma cell line in vitro and enhancement of hyperthermic response by bupivacaine.
Topics: Bupivacaine; Cell Survival; Hot Temperature; Humans; Hyperthermia, Induced; Melanoma; Thermodynamics | 1998 |
Detachment of the glycolytic enzymes, phosphofructokinase and aldolase, from cytoskeleton of melanoma cells, induced by local anesthetics.
Topics: Anesthetics, Local; Animals; Antineoplastic Agents; Bupivacaine; Cell Death; Cell Survival; Cytoskel | 2000 |