Page last updated: 2024-10-24

bupivacaine and Long QT Syndrome

bupivacaine has been researched along with Long QT Syndrome in 7 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.

Research Excerpts

ExcerptRelevanceReference
"We describe the case of a 9-yr-old child with undiagnosed long QT syndrome who experienced an intraoperative cardiac arrest after accidental intravascular injection of bupivacaine with epinephrine via a misplaced epidural catheter."3.72Unusual presentation of long QT syndrome. ( Cucchiaro, G; Rhodes, LA, 2003)
"Levobupivacaine was substituted for routine racemic bupivacaine to decrease the risk of drug-induced cardiotoxicity."1.33Long QT syndrome: anaesthetic management at delivery. ( Behl, S; Wauchob, TD, 2005)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dogan, Z1
Yildiz, H1
Akcay, A1
Coskuner, I1
Arikan, DC1
Silay, E1
Akbudak, IH1
Kaya, H1
Oksuz, H1
Grilo, LS1
Carrupt, PA1
Daina, A1
Naseem, A1
Harada, T1
Wang, D1
Arezina, R1
Lorch, U1
Onel, E1
Camm, AJ1
Taubel, J1
Cucchiaro, G1
Rhodes, LA1
Kameyama, E1
Ito, Y1
Ito, J1
Saito, K1
Murakami, N1
Horinouchi, T1
Kato, M1
Al-Refai, A1
Gunka, V1
Douglas, J1
Behl, S1
Wauchob, TD1

Trials

2 trials available for bupivacaine and Long QT Syndrome

ArticleYear
The effect of intraspinal bupivacaine versus levobupivacaine on the QTc intervals during caesarean section: a randomized, double-blind, prospective study.
    Basic & clinical pharmacology & toxicology, 2014, Volume: 114, Issue:3

    Topics: Adult; Anesthetics, Local; Bupivacaine; Cesarean Section; Double-Blind Method; Electrocardiography;

2014
Bupivacaine extended release liposome injection does not prolong QTc interval in a thorough QT/QTc study in healthy volunteers.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:9

    Topics: Adult; Anesthetics, Local; Anti-Infective Agents; Aza Compounds; Bupivacaine; Cross-Over Studies; De

2012

Other Studies

5 other studies available for bupivacaine and Long QT Syndrome

ArticleYear
Stereoselective block of hERG channel by bupivacaine scrutinized at molecular level.
    Chimia, 2010, Volume: 64, Issue:3

    Topics: Bupivacaine; Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Models

2010
Unusual presentation of long QT syndrome.
    British journal of anaesthesia, 2003, Volume: 90, Issue:6

    Topics: Anesthetics, Local; Bupivacaine; Child; Epinephrine; Heart Arrest; Humans; Intraoperative Complicati

2003
[Anesthetic management of caesarean section in a patient with asymptomatic idiopathic prolonged QT interval syndrome].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:10

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Bupivacaine; Cesarean Sect

2004
Spinal anesthesia for Cesarean section in a parturient with long QT syndrome.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:10

    Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Blood Pr

2004
Long QT syndrome: anaesthetic management at delivery.
    International journal of obstetric anesthesia, 2005, Volume: 14, Issue:4

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Anti-Arr

2005