bupivacaine has been researched along with Inflammation in 53 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Perineural or systemic dexamethasone had a protective effect against the neural inflammation induced by bupivacaine, and perineural dexamethasone attenuated delayed inflammation induced by perineural Exparel®." | 7.96 | Perineural dexamethasone attenuates liposomal bupivacaine-induced delayed neural inflammation in mice in vivo. ( Ancelin, D; Bennis, M; Brouchet, A; Cavaignac, E; Charre, A; Dray, C; Ferré, F; Krin, A; Kurrek, M; Marty, P; Minville, V; Sanchez, M, 2020) |
| "This study was designed to assess the correlation between the neuroprotective effect of dexmedetomidine and oxidative stress, neural inflammation and mast cell stability in rats with bupivacaine-induced sciatic nerve toxicity." | 7.79 | The protective effect of dexmedetomidine on bupivacaine-induced sciatic nerve inflammation is mediated by mast cells. ( Çelik, F; Evliyaoğlu, O; Firat, U; Karaman, H; Kaya, S; Tokgöz, O; Tüfek, A, 2013) |
| " The aim of this study was to compare the effects of bupivacaine via sciatic block with a systemic NSAID on oedema and hyperalgesia and on indices of systemic inflammation as measured by cytokines and prostaglandin E2 production in a model of peripheral inflammation in rats." | 7.76 | Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats. ( Beloeil, H; Benhamou, D; Combettes, E; Mazoit, JX, 2010) |
| " To elucidate potential mechanisms, the authors examined effects of bupivacaine or tetrodotoxin, administered to rats by ipsilateral or contralateral sciatic blockade or systemically, on carrageenan-induced hind paw hyperalgesia, edema, and stimulated cytokine production in circulating blood cells." | 7.73 | Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 1): hyperalgesia, edema, and systemic cytokines. ( Ababneh, Z; Beloeil, H; Berde, CB; Chung, R; Mulkern, RV; Zurakowski, D, 2006) |
| "The authors previously showed that bupivacaine and tetrodotoxin via contralateral or ipsilateral sciatic block, but not systemically, attenuate local edema and hyperalgesia induced by carrageenan hind paw injection in rats." | 7.73 | Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 2): cytokines and p38 mitogen-activated protein kinases in dorsal root ganglia and spinal cord. ( Beloeil, H; Berde, CB; Ji, RR, 2006) |
| "In both acute thermal- and inflammatory-induced pain, intrathecally administered midazolam and bupivacaine produced synergistic analgesia with decreased side effects in intrathecally catheterized rats." | 7.72 | Midazolam can potentiate the analgesic effects of intrathecal bupivacaine on thermal- or inflammatory-induced pain. ( Hanaoka, K; Nishiyama, T, 2003) |
| "We investigated the interaction between spinally administered bupivacaine and clonidine using an animal model of acute and inflammatory pain." | 7.72 | Intrathecal clonidine and bupivacaine have synergistic analgesia for acute thermally or inflammatory-induced pain in rats. ( Hanaoka, K; Nishiyama, T, 2004) |
| "Immunohistochemical analysis of the inflammatory cells and complement C3 in the rat skeletal muscle was performed chronologically in bupivacaine-induced myonecrosis." | 7.68 | Analysis of inflammatory cells and complement C3 in bupivacaine-induced myonecrosis. ( Arahata, K; Hiyamuta, E; Orimo, S; Sugita, H, 1991) |
| "Treatment with levobupivacaine inhibited the development of pain hypersensitivity for two hours." | 5.46 | Dexmedetomidine prolongs levobupivacaine analgesia via inhibition of inflammation and p38 MAPK phosphorylation in rat dorsal root ganglion. ( Amaya, F; Matsuda, M; Sawa, T; Yamaguchi, Y; Yamakita, S, 2017) |
| "Inflammation was induced by unilateral injection of either 50 or 100 microl of 1% carrageenan into the right paw." | 5.31 | Contralateral but not systemic administration of bupivacaine reduces acute inflammation in the rat hindpaw. ( Bileviciute-Ljungar, I; Lundeberg, T, 2000) |
| "The purpose of this study was to compare the extent of inflammation response in the middle carpal joints of healthy horses following intra-articular injection of 2% lidocaine, 0." | 4.31 | Effects of a Single Intra-Articular Injection of 2% Lidocaine or 0.5% Bupivacaine on Synovial Fluid Acute Phase Protein Concentrations in Healthy Horses. ( da Fonseca, LA; Di Filippo, PA; Dos Santos, GC; Quirino, CR, 2023) |
| "Both Bupivacaine concentrations effectively produced the desired muscle hypertrophy and fibrosis, so the lower concentration may be used for muscle strengthening to correct strabismus." | 4.12 | Histopathological changes in extraocular muscles of rabbits following injection of bupivacaine 5mg/Ml versus 7.5mg/Ml. ( Abdel-Salam, LO; Kassem, RR; Mohamed Abdel-Moneim El-Mofty, R, 2022) |
| "Perineural or systemic dexamethasone had a protective effect against the neural inflammation induced by bupivacaine, and perineural dexamethasone attenuated delayed inflammation induced by perineural Exparel®." | 3.96 | Perineural dexamethasone attenuates liposomal bupivacaine-induced delayed neural inflammation in mice in vivo. ( Ancelin, D; Bennis, M; Brouchet, A; Cavaignac, E; Charre, A; Dray, C; Ferré, F; Krin, A; Kurrek, M; Marty, P; Minville, V; Sanchez, M, 2020) |
| "This study was designed to assess the correlation between the neuroprotective effect of dexmedetomidine and oxidative stress, neural inflammation and mast cell stability in rats with bupivacaine-induced sciatic nerve toxicity." | 3.79 | The protective effect of dexmedetomidine on bupivacaine-induced sciatic nerve inflammation is mediated by mast cells. ( Çelik, F; Evliyaoğlu, O; Firat, U; Karaman, H; Kaya, S; Tokgöz, O; Tüfek, A, 2013) |
| "There were no significant differences between the levobupivacaine and control groups with respect to inflammation in the articular and periarticular tissues and the synovium." | 3.78 | Effect of intra-articular injection of levobupivacaine on articular cartilage and synovium in rats. ( Akinci, SB; Altinel, S; Asan, E; Aypar, U; Erden, IA; Saricaoglu, F; Zeybek, ND, 2012) |
| " The aim of this study was to compare the effects of bupivacaine via sciatic block with a systemic NSAID on oedema and hyperalgesia and on indices of systemic inflammation as measured by cytokines and prostaglandin E2 production in a model of peripheral inflammation in rats." | 3.76 | Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats. ( Beloeil, H; Benhamou, D; Combettes, E; Mazoit, JX, 2010) |
| " In this study, we evaluated the effect of bupivacaine administered via a nerve block or via a systemic route on the spinal expression of PGE2 and COX in a model of peripheral inflammation in rats." | 3.75 | The effect of a peripheral block on inflammation-induced prostaglandin E2 and cyclooxygenase expression in rats. ( Beloeil, H; Benhamou, D; Gentili, M; Mazoit, JX, 2009) |
| " To elucidate potential mechanisms, the authors examined effects of bupivacaine or tetrodotoxin, administered to rats by ipsilateral or contralateral sciatic blockade or systemically, on carrageenan-induced hind paw hyperalgesia, edema, and stimulated cytokine production in circulating blood cells." | 3.73 | Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 1): hyperalgesia, edema, and systemic cytokines. ( Ababneh, Z; Beloeil, H; Berde, CB; Chung, R; Mulkern, RV; Zurakowski, D, 2006) |
| "The authors previously showed that bupivacaine and tetrodotoxin via contralateral or ipsilateral sciatic block, but not systemically, attenuate local edema and hyperalgesia induced by carrageenan hind paw injection in rats." | 3.73 | Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 2): cytokines and p38 mitogen-activated protein kinases in dorsal root ganglia and spinal cord. ( Beloeil, H; Berde, CB; Ji, RR, 2006) |
| "In both acute thermal- and inflammatory-induced pain, intrathecally administered midazolam and bupivacaine produced synergistic analgesia with decreased side effects in intrathecally catheterized rats." | 3.72 | Midazolam can potentiate the analgesic effects of intrathecal bupivacaine on thermal- or inflammatory-induced pain. ( Hanaoka, K; Nishiyama, T, 2003) |
| "We investigated the interaction between spinally administered bupivacaine and clonidine using an animal model of acute and inflammatory pain." | 3.72 | Intrathecal clonidine and bupivacaine have synergistic analgesia for acute thermally or inflammatory-induced pain in rats. ( Hanaoka, K; Nishiyama, T, 2004) |
| "The analgesic and anti-inflammatory effects of subcutaneously administered bupivacaine, morphine and tramadol on formalin-induced inflammation were compared." | 3.72 | The analgesic and anti-inflammatory effects of subcutaneous bupivacaine, morphine and tramadol in rats. ( Eti, Z; Gerçek, A; Göğüş, FY; Sav, A, 2004) |
| "We have assessed the effects of intraplantar local anaesthetics (bupivacaine and lignocaine) on carrageenan-induced oedema, mechanical allodynia and spinal c-fos protein expression." | 3.69 | Effects of local anaesthetics on carrageenan-evoked inflammatory nociceptive processing in the rat. ( Besson, JM; Buritova, J; Fletcher, D; Honoré, P, 1996) |
| "Immunohistochemical analysis of the inflammatory cells and complement C3 in the rat skeletal muscle was performed chronologically in bupivacaine-induced myonecrosis." | 3.68 | Analysis of inflammatory cells and complement C3 in bupivacaine-induced myonecrosis. ( Arahata, K; Hiyamuta, E; Orimo, S; Sugita, H, 1991) |
| "Treatment with levobupivacaine inhibited the development of pain hypersensitivity for two hours." | 1.46 | Dexmedetomidine prolongs levobupivacaine analgesia via inhibition of inflammation and p38 MAPK phosphorylation in rat dorsal root ganglion. ( Amaya, F; Matsuda, M; Sawa, T; Yamaguchi, Y; Yamakita, S, 2017) |
| "Subsequently, sufentanil induced hyperalgesia in diabetic and non-diabetic mice." | 1.42 | Beneficial effects of levobupivacaine regional anaesthesia on postoperative opioid induced hyperalgesia in diabetic mice. ( Blaes, N; Fourcade, O; Francès, B; Girolami, JP; Gomez-Brouchet, A; Minville, V; Mouledous, L; Tack, I, 2015) |
| "Because inflammation is critical to both the development and resolution of VT, analgesic medications have the potential to adversely affect multiple parameters of interest in VT research." | 1.40 | Effects of analgesic use on inflammation and hematology in a murine model of venous thrombosis. ( Diaz, JA; Hawley, AE; Hish, GA; Lester, PA; Myers, DD, 2014) |
| "Inflammation was induced by unilateral injection of either 50 or 100 microl of 1% carrageenan into the right paw." | 1.31 | Contralateral but not systemic administration of bupivacaine reduces acute inflammation in the rat hindpaw. ( Bileviciute-Ljungar, I; Lundeberg, T, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (18.87) | 18.2507 |
| 2000's | 22 (41.51) | 29.6817 |
| 2010's | 17 (32.08) | 24.3611 |
| 2020's | 4 (7.55) | 2.80 |
| Authors | Studies |
|---|---|
| Weinschenk, S | 1 |
| Weiss, C | 1 |
| Benrath, J | 1 |
| von Baehr, V | 1 |
| Strowitzki, T | 1 |
| Feißt, M | 1 |
| Mohamed Abdel-Moneim El-Mofty, R | 1 |
| Kassem, RR | 1 |
| Abdel-Salam, LO | 1 |
| Dos Santos, GC | 1 |
| Di Filippo, PA | 1 |
| da Fonseca, LA | 1 |
| Quirino, CR | 1 |
| Ferré, F | 1 |
| Krin, A | 1 |
| Sanchez, M | 1 |
| Ancelin, D | 1 |
| Cavaignac, E | 1 |
| Charre, A | 1 |
| Bennis, M | 1 |
| Marty, P | 1 |
| Dray, C | 1 |
| Brouchet, A | 1 |
| Kurrek, M | 1 |
| Minville, V | 2 |
| Yamakita, S | 1 |
| Matsuda, M | 1 |
| Yamaguchi, Y | 1 |
| Sawa, T | 1 |
| Amaya, F | 1 |
| Tüfek, A | 1 |
| Kaya, S | 1 |
| Tokgöz, O | 1 |
| Firat, U | 1 |
| Evliyaoğlu, O | 1 |
| Çelik, F | 1 |
| Karaman, H | 1 |
| Binczak, M | 1 |
| Tournay, E | 1 |
| Billard, V | 1 |
| Rey, A | 1 |
| Jayr, C | 1 |
| De Andres, J | 1 |
| Asensio-Samper, JM | 1 |
| Fabregat-Cid, G | 1 |
| Leite, PE | 1 |
| Gandía, L | 1 |
| de Pascual, R | 1 |
| Nanclares, C | 1 |
| Colmena, I | 1 |
| Santos, WC | 1 |
| Lagrota-Candido, J | 1 |
| Quirico-Santos, T | 1 |
| Huang, YH | 1 |
| Yen, JC | 1 |
| Lee, JJ | 1 |
| Liao, JF | 1 |
| Liaw, WJ | 1 |
| Huang, CJ | 1 |
| Lirk, P | 1 |
| Picardi, S | 1 |
| Hollmann, MW | 1 |
| Hish, GA | 1 |
| Diaz, JA | 1 |
| Hawley, AE | 1 |
| Myers, DD | 1 |
| Lester, PA | 1 |
| Gomez-Brouchet, A | 1 |
| Blaes, N | 1 |
| Mouledous, L | 1 |
| Fourcade, O | 1 |
| Tack, I | 1 |
| Francès, B | 1 |
| Girolami, JP | 1 |
| Dort, J | 1 |
| Leblanc, N | 1 |
| Bryl, P | 1 |
| Fortin, MG | 1 |
| Carbonneau, ME | 1 |
| Lavigne, C | 1 |
| Jacques, H | 1 |
| Côte, CH | 1 |
| Tremblay, MH | 1 |
| Duchesne, E | 1 |
| Lapoite, BM | 1 |
| Campos, CR | 1 |
| Ocheltree, SM | 1 |
| Hom, S | 1 |
| Egleton, RD | 1 |
| Davis, TP | 1 |
| Brummett, CM | 1 |
| Norat, MA | 1 |
| Palmisano, JM | 1 |
| Lydic, R | 1 |
| Hoare, T | 1 |
| Bellas, E | 1 |
| Zurakowski, D | 2 |
| Kohane, DS | 2 |
| Persec, J | 1 |
| Persec, Z | 1 |
| Buković, D | 1 |
| Merc, V | 1 |
| Pavelić, J | 1 |
| Zupić, T | 1 |
| Beloeil, H | 5 |
| Gentili, M | 1 |
| Benhamou, D | 3 |
| Mazoit, JX | 3 |
| Türe, H | 1 |
| Eti, Z | 2 |
| Göğüş, FY | 2 |
| Düzgün, O | 1 |
| Mutlu, Z | 1 |
| Karabağli, P | 1 |
| Combettes, E | 1 |
| Bai, ZT | 1 |
| Liu, T | 1 |
| Jiang, F | 1 |
| Cheng, M | 1 |
| Pang, XY | 1 |
| Hua, LM | 1 |
| Shi, J | 1 |
| Zhou, JJ | 1 |
| Shu, XQ | 1 |
| Zhang, JW | 1 |
| Ji, YH | 1 |
| Gordon, SM | 1 |
| Mischenko, AV | 1 |
| Dionne, RA | 1 |
| Bedirli, N | 1 |
| Akyürek, N | 1 |
| Kurtipek, O | 1 |
| Kavutcu, M | 1 |
| Kartal, S | 1 |
| Bayraktar, AC | 1 |
| Erden, IA | 1 |
| Altinel, S | 1 |
| Saricaoglu, F | 1 |
| Zeybek, ND | 1 |
| Akinci, SB | 1 |
| Asan, E | 1 |
| Aypar, U | 1 |
| Horiguchi, T | 1 |
| Shibata, MA | 1 |
| Ito, Y | 1 |
| Eid, NA | 1 |
| Abe, M | 1 |
| Otsuki, Y | 1 |
| Sutherland, MA | 1 |
| Mellor, DJ | 1 |
| Stafford, KJ | 1 |
| Gregory, NG | 1 |
| Bruce, RA | 1 |
| Ward, RN | 1 |
| Leduc, C | 1 |
| Gentili, ME | 1 |
| Estèbe, JP | 1 |
| Le Corre, P | 2 |
| Moulinoux, JP | 1 |
| Ecoffey, C | 1 |
| Nishiyama, T | 2 |
| Hanaoka, K | 2 |
| Gerçek, A | 1 |
| Sav, A | 1 |
| Asehnoune, K | 1 |
| Moine, P | 1 |
| Mukherji, S | 1 |
| Esakowitz, L | 1 |
| Hill, SE | 1 |
| Keller, RA | 1 |
| Stafford-Smith, M | 1 |
| Grichnik, K | 1 |
| White, WD | 1 |
| D'Amico, TA | 1 |
| Newman, MF | 1 |
| Ababneh, Z | 1 |
| Chung, R | 1 |
| Mulkern, RV | 1 |
| Berde, CB | 2 |
| Ji, RR | 1 |
| Greenbaum, S | 1 |
| Kiliçkan, L | 1 |
| Yumuk, Z | 1 |
| Bayindir, O | 1 |
| Buritova, J | 1 |
| Fletcher, D | 3 |
| Honoré, P | 1 |
| Besson, JM | 1 |
| Guilbaud, G | 2 |
| Le Verge, R | 1 |
| Kayser, V | 1 |
| Giordano, J | 1 |
| Sacks, SM | 1 |
| McLoon, LK | 1 |
| Nguyen, LT | 1 |
| Wirtschafter, J | 1 |
| Rasmussen, S | 1 |
| Larsen, AS | 1 |
| Thomsen, ST | 1 |
| Kehlet, H | 1 |
| Bengtsson, A | 1 |
| Avall, A | 1 |
| Hyllner, M | 1 |
| Bengtson, JP | 1 |
| Bileviciute-Ljungar, I | 1 |
| Lundeberg, T | 1 |
| Goto, Y | 1 |
| Ho, SL | 1 |
| McAdoo, J | 1 |
| Fanning, NF | 1 |
| Wang, J | 1 |
| Redmond, HP | 1 |
| Shorten, GD | 1 |
| Howard, RF | 1 |
| Hatch, DJ | 1 |
| Cole, TJ | 1 |
| Fitzgerald, M | 1 |
| Lipp, M | 1 |
| Kinney, RC | 1 |
| Anthony, DC | 1 |
| Louis, DN | 1 |
| Lotan, N | 1 |
| Langer, R | 1 |
| Orimo, S | 1 |
| Hiyamuta, E | 1 |
| Arahata, K | 1 |
| Sugita, H | 1 |
| Levine, JD | 1 |
| Coderre, TJ | 1 |
| White, DM | 1 |
| Finkbeiner, WE | 1 |
| Basbaum, AI | 1 |
| Guttu, RL | 1 |
| Page, DG | 1 |
| Laskin, DM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Dexmedetomidine Combined With Ropivacaine for Postoperative Continuous Femoral Nerve Block on Postoperative Delirium and Long-term Oucomes in Elderly Patients After Single Knee Arthroplasty[NCT03629483] | Phase 4 | 736 participants (Anticipated) | Interventional | 2018-12-10 | Suspended (stopped due to Trial stopped by the sponsor because of no funding.) | ||
| Dexmedetomidine Versus Triamcinolone Local Injection for Pain Alleviation in Patients With Carpal Tunnel Syndrome; A Randomized Clinical Trial[NCT04961281] | 60 participants (Actual) | Interventional | 2021-07-22 | Completed | |||
| The Effect of Dexamedetomidine for Interscalene Brachial Plexus Block on Plasma Cortisol and IL-6 After Rotator Cuff Repair: a Prospective Randomized Study[NCT02766556] | 50 participants (Actual) | Interventional | 2014-08-31 | Completed | |||
| Efficacy of Two Dental Local Anesthetics on the Oral Health-Related Quality of Life After Endodontic Treatment in the Symptomatic Mandibular Molars: A Double Blind Randomized Controlled Trial[NCT04787731] | Phase 4 | 100 participants (Anticipated) | Interventional | 2019-07-29 | Suspended (stopped due to COVID-19 and Personnel changes) | ||
| Radiological Evaluation of Thoracic Paravertebral Catheters: A Prospective Clinical Trial[NCT01009398] | 30 participants (Actual) | Observational | 2009-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for bupivacaine and Inflammation
| Article | Year |
|---|---|
Intrathecal delivery of analgesics.
Topics: Analgesics, Opioid; Baclofen; Bupivacaine; Catheters, Indwelling; Chronic Pain; Clonidine; Drug Deli | 2014 |
Local anaesthetics: 10 essentials.
Topics: Anesthetics, Local; Animals; Bupivacaine; Dose-Response Relationship, Drug; Humans; Inflammation; Li | 2014 |
Long-acting local anesthetics and perioperative pain management.
Topics: Anesthesia, Dental; Anesthetics, Local; Bupivacaine; Humans; Inflammation; Nociceptors; Pain Percept | 2010 |
7 trials available for bupivacaine and Inflammation
| Article | Year |
|---|---|
Preoperative clonidine or levobupivacaine--effect on systemic inflammatory stress response.
Topics: Adrenergic alpha-Agonists; Analgesia, Epidural; Anesthetics, Local; Biomarkers; Bupivacaine; Clonidi | 2009 |
Cortisol responses to dehorning of calves given a 5-h local anaesthetic regimen plus phenylbutazone, ketoprofen, or adrenocorticotropic hormone prior to dehorning.
Topics: Adrenocorticotropic Hormone; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; B | 2002 |
Efficacy of single-dose, multilevel paravertebral nerve blockade for analgesia after thoracoscopic procedures.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Fem | 2006 |
The effect of combined preinduction thoracic epidural anaesthesia and glucocorticoid administration on perioperative interleukin-10 levels and hyperglycemia. A randomized controlled trial.
Topics: Aged; Anesthesia, Epidural; Anesthetics, Local; Blood Glucose; Bupivacaine; Cardiopulmonary Bypass; | 2008 |
Intra-articular glucocorticoid, bupivacaine and morphine reduces pain, inflammatory response and convalescence after arthroscopic meniscectomy.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents; Arthroscopy; Bu | 1998 |
Formation of complement split products and proinflammatory cytokines by reinfusion of shed autologous blood.
Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Blood Pressure; Blood Transfusion, | 1998 |
General versus regional anaesthesia for cataract surgery: effects on neutrophil apoptosis and the postoperative pro-inflammatory state.
Topics: Aged; Analysis of Variance; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Inhalation; Anes | 2000 |
43 other studies available for bupivacaine and Inflammation
| Article | Year |
|---|---|
Anti-Inflammatory Characteristics of Local Anesthetics: Inhibition of TNF-α Secretion of Lipopolysaccharide-Stimulated Leucocytes in Human Blood Samples.
Topics: Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Humans; Inflammation; Lidocaine; Lipopoly | 2022 |
Histopathological changes in extraocular muscles of rabbits following injection of bupivacaine 5mg/Ml versus 7.5mg/Ml.
Topics: Bupivacaine; Fibrosis; Humans; Hyperemia; Hypertrophy; Inflammation; Oculomotor Muscles; Strabismus; | 2022 |
Effects of a Single Intra-Articular Injection of 2% Lidocaine or 0.5% Bupivacaine on Synovial Fluid Acute Phase Protein Concentrations in Healthy Horses.
Topics: Acute-Phase Proteins; Animals; Bupivacaine; Horse Diseases; Horses; Inflammation; Injections, Intra- | 2023 |
Perineural dexamethasone attenuates liposomal bupivacaine-induced delayed neural inflammation in mice in vivo.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents; Bupivacaine; Dexamethasone; Disease Models, A | 2020 |
Dexmedetomidine prolongs levobupivacaine analgesia via inhibition of inflammation and p38 MAPK phosphorylation in rat dorsal root ganglion.
Topics: Animals; Bupivacaine; Dexmedetomidine; Ganglia, Spinal; Inflammation; Levobupivacaine; Male; Neurons | 2017 |
The protective effect of dexmedetomidine on bupivacaine-induced sciatic nerve inflammation is mediated by mast cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Local; Animals; Antioxidants; Aryldialkylphosphat | 2013 |
Major abdominal surgery for cancer: does epidural analgesia have a long-term effect on recurrence-free and overall survival?
Topics: Abdominal Neoplasms; Adult; Aged; Analgesia, Epidural; Anesthesia, Conduction; Anesthesia, General; | 2013 |
Selective activation of α7 nicotinic acetylcholine receptor (nAChRα7) inhibits muscular degeneration in mdx dystrophic mice.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; | 2014 |
P2X7 is involved in the anti-inflammation effects of levobupivacaine.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cell Communication; Cell Line, Transformed; Cell Survival; | 2015 |
Effects of analgesic use on inflammation and hematology in a murine model of venous thrombosis.
Topics: Analgesics; Anesthetics, Local; Animals; Bupivacaine; Buprenorphine; Carbazoles; Disease Models, Ani | 2014 |
Beneficial effects of levobupivacaine regional anaesthesia on postoperative opioid induced hyperalgesia in diabetic mice.
Topics: Analgesics, Opioid; Anesthesia, Conduction; Animals; Bupivacaine; Diabetes Mellitus, Experimental; H | 2015 |
Shrimp Protein Hydrolysate Modulates the Timing of Proinflammatory Macrophages in Bupivacaine-Injured Skeletal Muscles in Rats.
Topics: Animals; Bupivacaine; Caseins; Inflammation; Macrophages; Muscle, Skeletal; Pandalidae; Protein Hydr | 2016 |
Inflammation-induced leukocyte accumulation in injured skeletal muscle: role of mast cells.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cell Degranulation; Cytoplasmic Granules; Immunohistochemi | 2008 |
Nociceptive inhibition prevents inflammatory pain induced changes in the blood-brain barrier.
Topics: Anesthetics, Local; Animals; Blood-Brain Barrier; Brain Edema; Bupivacaine; Carrageenan; Claudin-5; | 2008 |
Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Bupivacaine; Dexmedetomidine; Dose-Response R | 2008 |
Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Bupivacaine; Dexmedetomidine; Dose-Response R | 2008 |
Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Bupivacaine; Dexmedetomidine; Dose-Response R | 2008 |
Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Bupivacaine; Dexmedetomidine; Dose-Response R | 2008 |
Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Bupivacaine; Dexmedetomidine; Dose-Response R | 2008 |
Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Bupivacaine; Dexmedetomidine; Dose-Response R | 2008 |
Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Bupivacaine; Dexmedetomidine; Dose-Response R | 2008 |
Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Bupivacaine; Dexmedetomidine; Dose-Response R | 2008 |
Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Bupivacaine; Dexmedetomidine; Dose-Response R | 2008 |
Rheological blends for drug delivery. II. Prolongation of nerve blockade, biocompatibility, and in vitro-in vivo correlations.
Topics: Anesthetics, Local; Animals; Biocompatible Materials; Bupivacaine; Cell Line; Coloring Agents; Drug | 2010 |
The effect of a peripheral block on inflammation-induced prostaglandin E2 and cyclooxygenase expression in rats.
Topics: Animals; Bupivacaine; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Edema; Gene Expression Regul | 2009 |
Histopathological effects on epidural tissue of bolus or continuous infusions through an epidural catheter in ewes.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Bupivacaine; Drug Administration Schedule; Epidural | 2010 |
Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Dinoprostone; Dis | 2010 |
Phenotypes and peripheral mechanisms underlying inflammatory pain-related behaviors induced by BmK I, a modulator of sodium channels.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, | 2010 |
Thoracic epidural bupivacaine attenuates inflammatory response, intestinal lipid peroxidation, oxidative injury, and mucosal apoptosis induced by mesenteric ischemia/reperfusion.
Topics: Anesthesia, Epidural; Anesthetics, Local; Animals; Apoptosis; Bupivacaine; Catalase; Catheterization | 2011 |
Effect of intra-articular injection of levobupivacaine on articular cartilage and synovium in rats.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cartilage, Articular; Inflammation; Injections, Intra-Arti | 2012 |
Macrophage apoptosis in rat skeletal muscle treated with bupivacaine hydrochloride: possible role of MCP-1.
Topics: Anesthetics, Local; Animals; Apoptosis; Bupivacaine; Chemokine CCL2; Immunohistochemistry; In Situ N | 2002 |
The effect of local anesthetics and amitriptyline on peroxidation in vivo in an inflammatory rat model: preliminary reports.
Topics: Amides; Amitriptyline; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Bupivacaine; C | 2002 |
Midazolam can potentiate the analgesic effects of intrathecal bupivacaine on thermal- or inflammatory-induced pain.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Animals; Behavior, Animal; Bupivacaine; Dose-Response | 2003 |
Intrathecal clonidine and bupivacaine have synergistic analgesia for acute thermally or inflammatory-induced pain in rats.
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Animals; Behavior, Animal; Bupivacaine; Clonidine; Do | 2004 |
The analgesic and anti-inflammatory effects of subcutaneous bupivacaine, morphine and tramadol in rats.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Bupivacaine; Formaldehyde; Inflammation; Injections | 2004 |
Bupivacaine's action on the carrageenan-induced inflammatory response in mice: cytokine production by leukocytes after ex-vivo stimulation.
Topics: Anesthetics, Local; Animals; Bupivacaine; Carrageenan; Cytokines; Inflammation; Interleukin-1; Inter | 2005 |
Orbital inflammation after sub-Tenon's anesthesia.
Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Fascia; Female; Glu | 2005 |
Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 1): hyperalgesia, edema, and systemic cytokines.
Topics: Animals; Bupivacaine; Carrageenan; Drug Therapy, Combination; Edema; Hindlimb; Inflammation; Male; R | 2006 |
Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 2): cytokines and p38 mitogen-activated protein kinases in dorsal root ganglia and spinal cord.
Topics: Animals; Bupivacaine; Carrageenan; Cytokines; Drug Therapy, Combination; Edema; Ganglia, Spinal; Hin | 2006 |
Orbital inflammation after posterior sub-Tenon's anesthesia.
Topics: Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Fascia; Glucocorticoids; | 2006 |
Effects of local anaesthetics on carrageenan-evoked inflammatory nociceptive processing in the rat.
Topics: Anesthetics, Local; Animals; Bupivacaine; Carrageenan; Edema; Inflammation; Lidocaine; Male; Nocicep | 1996 |
Antinociceptive effect of bupivacaine encapsulated in poly(D,L)-lactide-co-glycolide microspheres in the acute inflammatory pain model of carrageenin-injected rats.
Topics: Acute Disease; Anesthetics, Local; Animals; Bupivacaine; Carrageenan; Drug Compounding; Inflammation | 1997 |
The influence of the timing of bupivacaine infiltration on the time course of inflammation induced by two carrageenin injections seven days apart.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Bupivacaine; Carrageenan; Drug Administration Sch | 1997 |
Sub-anesthetic doses of bupivacaine or lidocaine increase peripheral ICS-205 930-induced analgesia against inflammatory pain in rats.
Topics: Analgesia; Anesthetics, Local; Animals; Bupivacaine; Drug Synergism; Indoles; Inflammation; Lidocain | 1997 |
Time course of the regenerative response in bupivacaine injured orbicularis oculi muscle.
Topics: Animals; Bupivacaine; Cell Movement; Eyelids; Facial Muscles; Hyaluronoglucosaminidase; Inflammation | 1998 |
Contralateral but not systemic administration of bupivacaine reduces acute inflammation in the rat hindpaw.
Topics: Anesthetics, Local; Animals; Bupivacaine; Carrageenan; Functional Laterality; Hot Temperature; Infla | 2000 |
Inflammatory pain and hypersensitivity are selectively reversed by epidural bupivacaine and are developmentally regulated.
Topics: Aging; Analgesia, Epidural; Anesthetics, Local; Animals; Bupivacaine; Carrageenan; Dose-Response Rel | 2001 |
Biocompatibility of lipid-protein-sugar particles containing bupivacaine in the epineurium.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Anesthetics, Local; Animals; Biocompatible Materials; Bupivacain | 2002 |
Analysis of inflammatory cells and complement C3 in bupivacaine-induced myonecrosis.
Topics: Animals; Antibodies, Monoclonal; Bupivacaine; Complement C3; Hindlimb; Immunohistochemistry; Inflamm | 1991 |
Denervation-induced inflammation in the rat.
Topics: Animals; Bupivacaine; Capsaicin; Denervation; Electric Stimulation; Foot; Hindlimb; Inflammation; Ma | 1990 |
Delayed healing of muscle after injection of bupivicaine and steroid.
Topics: Animals; Bupivacaine; Drug Combinations; Hindlimb; Inflammation; Injections, Intramuscular; Male; Mu | 1990 |