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bupivacaine and Inflammation, Endodontic

bupivacaine has been researched along with Inflammation, Endodontic in 8 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Research Excerpts

ExcerptRelevanceReference
"Although liposomal bupivacaine had some effect on soft tissue anesthesia, it did not reduce pain to manageable clinical levels in patients presenting with untreated, symptomatic irreversible pulpitis."9.22Pain Reduction in Untreated Symptomatic Irreversible Pulpitis Using Liposomal Bupivacaine (Exparel): A Prospective, Randomized, Double-blind Trial. ( Beck, M; Bultema, K; Drum, M; Fowler, S; Nusstein, J; Reader, A, 2016)
"5% bupivacaine with 1:200,000 epinephrine with that of 2% lidocaine with 1:100,000 epinephrine during pulpectomy in patients with irreversible pulpitis in mandibular posterior teeth."9.16Comparison of the anesthetic efficacy between bupivacaine and lidocaine in patients with irreversible pulpitis of mandibular molar. ( Carnaval, TG; Horliana, AC; Lanfredi, CB; Rocha, RG; Sampaio, RM; Tortamano, IP, 2012)
"Patients who received bupivacaine as the anesthetic agent for single-visit endodontic treatment of irreversible pulpitis in mandibular molars had significantly less early postoperative pain and used fewer analgesics than those who had lidocaine as the anesthetic."9.16Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis. ( Abbott, PV; Manochehrifar, H; Nakhaee, N; Parirokh, M; Reza Forghani, F; Yosefi, MH, 2012)
" Five RCTs suggest that both benzocaine 10% and 20% may increase the number of people experiencing pain reduction compared with placebo when managing acute irreversible pulpitis (low certainty)."5.41Injectable and topical local anesthetics for acute dental pain: 2 systematic reviews. ( Azab, M; Brignardello-Petersen, R; Carrasco-Labra, A; Diaz Martinez, JP; He, L; Hersh, EV; Ibrahim, S; Miroshnychenko, A; Moore, PA; Polk, DE; Roldan, Y; Tamilselvan, D; Tampi, M; Urquhart, O, 2023)
"5% Bupivacaine with 1:200,000 epinephrine in one-visit root canal treatment in patients with symptomatic irreversible pulpitis."5.34Determination of Anesthetic Efficacy of Lidocaine Versus Bupivacaine in Single Visit Root Canal Treatment. ( Ahmed, MA; Ghani, B; Jouhar, R, 2020)
"Although liposomal bupivacaine had some effect on soft tissue anesthesia, it did not reduce pain to manageable clinical levels in patients presenting with untreated, symptomatic irreversible pulpitis."5.22Pain Reduction in Untreated Symptomatic Irreversible Pulpitis Using Liposomal Bupivacaine (Exparel): A Prospective, Randomized, Double-blind Trial. ( Beck, M; Bultema, K; Drum, M; Fowler, S; Nusstein, J; Reader, A, 2016)
"5% bupivacaine with 1:200,000 epinephrine with that of 2% lidocaine with 1:100,000 epinephrine during pulpectomy in patients with irreversible pulpitis in mandibular posterior teeth."5.16Comparison of the anesthetic efficacy between bupivacaine and lidocaine in patients with irreversible pulpitis of mandibular molar. ( Carnaval, TG; Horliana, AC; Lanfredi, CB; Rocha, RG; Sampaio, RM; Tortamano, IP, 2012)
"Patients who received bupivacaine as the anesthetic agent for single-visit endodontic treatment of irreversible pulpitis in mandibular molars had significantly less early postoperative pain and used fewer analgesics than those who had lidocaine as the anesthetic."5.16Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis. ( Abbott, PV; Manochehrifar, H; Nakhaee, N; Parirokh, M; Reza Forghani, F; Yosefi, MH, 2012)
" There was no statistically significance in adverse events between two groups."2.50Efficacy and safety of bupivacaine versus lidocaine in dental treatments: a meta-analysis of randomised controlled trials. ( Huang, Y; Liao, S; Su, N; Wang, H; Yang, S; Zhang, S, 2014)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Miroshnychenko, A1
Ibrahim, S1
Azab, M1
Roldan, Y1
Diaz Martinez, JP1
Tamilselvan, D1
He, L1
Urquhart, O1
Tampi, M1
Polk, DE1
Moore, PA1
Hersh, EV1
Carrasco-Labra, A1
Brignardello-Petersen, R1
Jouhar, R1
Ahmed, MA1
Ghani, B1
Su, N1
Wang, H1
Zhang, S1
Liao, S1
Yang, S1
Huang, Y1
Bultema, K1
Fowler, S1
Drum, M1
Reader, A1
Nusstein, J1
Beck, M1
Sampaio, RM1
Carnaval, TG1
Lanfredi, CB1
Horliana, AC1
Rocha, RG1
Tortamano, IP1
Parirokh, M1
Yosefi, MH1
Nakhaee, N1
Manochehrifar, H1
Abbott, PV1
Reza Forghani, F1
Hsiao-Wu, GW1
Susarla, SM1
White, RR1
Walton, RE1
Torabinejad, M1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Two Dental Local Anesthetics on the Oral Health-Related Quality of Life After Endodontic Treatment in the Symptomatic Mandibular Molars: A Double Blind Randomized Controlled Trial[NCT04787731]Phase 4100 participants (Anticipated)Interventional2019-07-29Suspended (stopped due to COVID-19 and Personnel changes)
Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment[NCT05338671]Phase 440 participants (Anticipated)Interventional2021-09-29Active, not recruiting
Evaluation of the Efficiency of Intraligamentary + Buccal Infiltration Anesthesia and Inferior Alveolar Nerve Block + Buccal Infiltration Anesthesia in Symptomatic Mandibular Molars With Irreversible Pulpitis[NCT05839093]210 participants (Actual)Interventional2021-12-21Completed
Efficacy of the Combination Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis: a Randomized Clinical Trial.[NCT02110966]Phase 456 participants (Actual)Interventional2014-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for bupivacaine and Inflammation, Endodontic

ArticleYear
Injectable and topical local anesthetics for acute dental pain: 2 systematic reviews.
    Journal of the American Dental Association (1939), 2023, Volume: 154, Issue:1

    Topics: Acute Pain; Anesthesia, Local; Anesthetics, Local; Benzocaine; Bupivacaine; Epinephrine; Humans; Lid

2023
Efficacy and safety of bupivacaine versus lidocaine in dental treatments: a meta-analysis of randomised controlled trials.
    International dental journal, 2014, Volume: 64, Issue:1

    Topics: Analgesics; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Dental Pulp; Epi

2014

Trials

5 trials available for bupivacaine and Inflammation, Endodontic

ArticleYear
Determination of Anesthetic Efficacy of Lidocaine Versus Bupivacaine in Single Visit Root Canal Treatment.
    European endodontic journal, 2020, Volume: 5, Issue:2

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Female; Follow-Up Studies; Humans; Inject

2020
Pain Reduction in Untreated Symptomatic Irreversible Pulpitis Using Liposomal Bupivacaine (Exparel): A Prospective, Randomized, Double-blind Trial.
    Journal of endodontics, 2016, Volume: 42, Issue:12

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Dental; Anesthesia,

2016
Comparison of the anesthetic efficacy between bupivacaine and lidocaine in patients with irreversible pulpitis of mandibular molar.
    Journal of endodontics, 2012, Volume: 38, Issue:5

    Topics: Adolescent; Adult; Anesthetics, Local; Bupivacaine; Dental Pulp; Dental Pulp Test; Double-Blind Meth

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
    Journal of endodontics, 2012, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

2012
Use of the cold test as a measure of pulpal anesthesia during endodontic therapy: a randomized, blinded, placebo-controlled clinical trial.
    Journal of endodontics, 2007, Volume: 33, Issue:4

    Topics: Adult; Age Factors; Anesthesia, Dental; Anesthetics, Local; Bupivacaine; Cold Temperature; Dental Pu

2007

Other Studies

1 other study available for bupivacaine and Inflammation, Endodontic

ArticleYear
Managing local anesthesia problems in the endodontic patient.
    Journal of the American Dental Association (1939), 1992, Volume: 123, Issue:5

    Topics: Anesthesia, Dental; Anesthesia, Local; Bupivacaine; Dental Pulp; Injections; Lidocaine; Mandible; Mo

1992