bupivacaine has been researched along with Hypospadias in 28 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Hypospadias: A birth defect due to malformation of the URETHRA in which the urethral opening is below its normal location. In the male, the malformed urethra generally opens on the ventral surface of the PENIS or on the PERINEUM. In the female, the malformed urethral opening is in the VAGINA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spinal anesthesia provided by hyperbaric bupivacaine is adequate for distal hypospadias repair in children, but adding 2 microg x kg(-1) intrathecal morphine provides better postoperative pain control when compared to placebo in these children." | 9.14 | Efficacy of a low-dose spinal morphine with bupivacaine for postoperative analgesia in children undergoing hypospadias repair. ( Akillioglu, I; Apiliogullari, S; Ciftci, I; Duman, A; Gok, F, 2009) |
| "To compare the effects after caudal bupivacaine alone and bupivacaine-tramadol in young children with hypospadias repair." | 9.13 | Comparison of caudal bupivacaine and bupivacaine-tramadol for postoperative analgesia in children with hypospadias repair. ( Khan, S; Memon, MI, 2008) |
| " clonidine on postoperative analgesia produced by caudal bupivacaine after hypospadias repair." | 9.11 | Caudal bupivacaine supplemented with caudal or intravenous clonidine in children undergoing hypospadias repair: a double-blind study. ( Hansen, M; Hansen, TG; Henneberg, SW; Lund, J; Walther-Larsen, S, 2004) |
| "Caudal neostigmine 2 micro g/kg provides postoperative analgesia comparable to caudal bupivacaine in children undergoing hypospadias repair surgery." | 9.10 | Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children. ( Abdulatif, M; El-Sanabary, M, 2002) |
| "In a prospective double-blind study, 40 children scheduled for hypospadias repair were allocated randomly to receive either caudal tramadol (1 mg/kg) or 0." | 9.09 | Comparison of caudal tramadol vs bupivacaine for post-operative analgesia in children undergoing hypospadias surgery. ( Arya, VK; Batra, YK; Chari, P; Prasad, MK; Yaddanapudi, LN, 1999) |
| "To assess our study design and to obtain preliminary data for a dose-effect study on levobupivacaine for caudal analgesia in patients undergoing hypospadias repair." | 7.76 | Longer than expected-duration of caudal analgesia with two different doses of levobupivacaine in children undergoing hypospadias repair. ( de Gier, R; Driessen, J; Feitz, W; Kho, HG; Knoll, J; Kwak, K; Thies, KC, 2010) |
| "To compare the effectiveness of caudal bupivacaine and bupivacaine-tramadol for postoperative analgesia in children undergoing hypospadias surgery." | 7.75 | Comparison of caudal bupivacaine and bupivacaine-tramadol for postoperative analgesia in children undergoing hypospadias surgery. ( Gandapur, YK; Khan, MN; Khan, S; Laiq, N, 2009) |
| "Postoperative pain was assessed hourly for 12 h after injection using a modified TPPPS pain score and additional analgesia was administered to those children whose pain scores were > 3/10." | 6.68 | Caudal tramadol for postoperative analgesia in pediatric hypospadias surgery. ( Booker, PD; Davis, A; Murray, A; Prosser, DP, 1997) |
| "Spinal anesthesia provided by hyperbaric bupivacaine is adequate for distal hypospadias repair in children, but adding 2 microg x kg(-1) intrathecal morphine provides better postoperative pain control when compared to placebo in these children." | 5.14 | Efficacy of a low-dose spinal morphine with bupivacaine for postoperative analgesia in children undergoing hypospadias repair. ( Akillioglu, I; Apiliogullari, S; Ciftci, I; Duman, A; Gok, F, 2009) |
| "To compare the effects after caudal bupivacaine alone and bupivacaine-tramadol in young children with hypospadias repair." | 5.13 | Comparison of caudal bupivacaine and bupivacaine-tramadol for postoperative analgesia in children with hypospadias repair. ( Khan, S; Memon, MI, 2008) |
| " clonidine on postoperative analgesia produced by caudal bupivacaine after hypospadias repair." | 5.11 | Caudal bupivacaine supplemented with caudal or intravenous clonidine in children undergoing hypospadias repair: a double-blind study. ( Hansen, M; Hansen, TG; Henneberg, SW; Lund, J; Walther-Larsen, S, 2004) |
| "2 mg x kg(-1) x h(-1)) postoperative epidural infusions of bupivacaine (Group B; n = 28), levobupivacaine (Group L; n = 27), and ropivacaine (Group R; n = 26) in children after hypospadias repair." | 5.11 | A comparison of epidural bupivacaine, levobupivacaine, and ropivacaine on postoperative analgesia and motor blockade. ( De Negri, P; Eksborg, S; Ivani, G; Lonnqvist, PA; Modano, P; Reato, C; Tirri, T, 2004) |
| "Caudal neostigmine 2 micro g/kg provides postoperative analgesia comparable to caudal bupivacaine in children undergoing hypospadias repair surgery." | 5.10 | Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children. ( Abdulatif, M; El-Sanabary, M, 2002) |
| "In a prospective double-blind study, 40 children scheduled for hypospadias repair were allocated randomly to receive either caudal tramadol (1 mg/kg) or 0." | 5.09 | Comparison of caudal tramadol vs bupivacaine for post-operative analgesia in children undergoing hypospadias surgery. ( Arya, VK; Batra, YK; Chari, P; Prasad, MK; Yaddanapudi, LN, 1999) |
| "25% bupivacaine either before (group A) or after (group B) Mathieu repair of distal hypospadias." | 5.06 | Caudal epidural anesthesia reduces blood loss during hypospadias repair. ( Forestner, JE; Gunter, JB; Manley, CB, 1990) |
| "To assess our study design and to obtain preliminary data for a dose-effect study on levobupivacaine for caudal analgesia in patients undergoing hypospadias repair." | 3.76 | Longer than expected-duration of caudal analgesia with two different doses of levobupivacaine in children undergoing hypospadias repair. ( de Gier, R; Driessen, J; Feitz, W; Kho, HG; Knoll, J; Kwak, K; Thies, KC, 2010) |
| "To compare the effectiveness of caudal bupivacaine and bupivacaine-tramadol for postoperative analgesia in children undergoing hypospadias surgery." | 3.75 | Comparison of caudal bupivacaine and bupivacaine-tramadol for postoperative analgesia in children undergoing hypospadias surgery. ( Gandapur, YK; Khan, MN; Khan, S; Laiq, N, 2009) |
| "Postoperative pain was assessed hourly for 12 h after injection using a modified TPPPS pain score and additional analgesia was administered to those children whose pain scores were > 3/10." | 2.68 | Caudal tramadol for postoperative analgesia in pediatric hypospadias surgery. ( Booker, PD; Davis, A; Murray, A; Prosser, DP, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.14) | 18.7374 |
| 1990's | 8 (28.57) | 18.2507 |
| 2000's | 11 (39.29) | 29.6817 |
| 2010's | 7 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ayubi, E | 1 |
| Safiri, S | 1 |
| Haydar, B | 2 |
| Canning, DA | 1 |
| Ayob, F | 1 |
| Arnold, R | 1 |
| Lee, JH | 1 |
| Shin, SK | 1 |
| Kim, MH | 1 |
| Khan, S | 2 |
| Memon, MI | 1 |
| Chiang, D | 1 |
| Pout, K | 1 |
| Ben-Meir, D | 1 |
| Dewan, P | 1 |
| Apiliogullari, S | 1 |
| Duman, A | 1 |
| Gok, F | 1 |
| Akillioglu, I | 1 |
| Ciftci, I | 1 |
| Laiq, N | 1 |
| Khan, MN | 1 |
| Gandapur, YK | 1 |
| Thies, KC | 1 |
| Driessen, J | 1 |
| Kho, HG | 1 |
| Kwak, K | 1 |
| Knoll, J | 1 |
| de Gier, R | 1 |
| Feitz, W | 1 |
| Abdulatif, M | 1 |
| El-Sanabary, M | 1 |
| Hansen, TG | 1 |
| Henneberg, SW | 1 |
| Walther-Larsen, S | 1 |
| Lund, J | 1 |
| Hansen, M | 1 |
| De Negri, P | 1 |
| Ivani, G | 1 |
| Tirri, T | 1 |
| Modano, P | 1 |
| Reato, C | 1 |
| Eksborg, S | 1 |
| Lonnqvist, PA | 1 |
| Ozyuvaci, E | 1 |
| Altan, A | 1 |
| Yucel, M | 1 |
| Yenmez, K | 1 |
| Jensen, BH | 1 |
| Atallah, MM | 1 |
| Saied, MM | 1 |
| Yahya, R | 1 |
| Ghaly, AM | 1 |
| Kelleher, AA | 1 |
| Black, A | 1 |
| Penman, S | 1 |
| Howard, R | 1 |
| Chhibber, AK | 1 |
| Perkins, FM | 1 |
| Rabinowitz, R | 1 |
| Vogt, AW | 1 |
| Hulbert, WC | 1 |
| Prosser, DP | 1 |
| Davis, A | 1 |
| Booker, PD | 1 |
| Murray, A | 1 |
| Batra, YK | 1 |
| Prasad, MK | 1 |
| Arya, VK | 1 |
| Chari, P | 1 |
| Yaddanapudi, LN | 1 |
| De Mey, JC | 1 |
| Strobbet, J | 1 |
| Poelaert, J | 1 |
| Hoebeke, P | 1 |
| Mortier, E | 1 |
| Karmakar, MK | 1 |
| Aun, CS | 1 |
| Wong, EL | 1 |
| Wong, AS | 1 |
| Chan, SK | 1 |
| Yeung, CK | 1 |
| Samuel, M | 1 |
| Hampson-Evans, D | 1 |
| Cunnington, P | 1 |
| Bacon, AK | 1 |
| Malviya, S | 1 |
| Fear, DW | 1 |
| Roy, WL | 1 |
| Lerman, J | 1 |
| Girotra, S | 1 |
| Kumar, S | 1 |
| Rajendran, KM | 1 |
| Gunter, JB | 1 |
| Forestner, JE | 1 |
| Manley, CB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Intravenous Paracetamol in Combination With Caudal Ropivacaine on Quality of Postoperative Recovery in Paediatric Patients Undergoing Hypospadias Repair[NCT03781505] | Phase 4 | 64 participants (Anticipated) | Interventional | 2019-01-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 trials available for bupivacaine and Hypospadias
| Article | Year |
|---|---|
Comparison of caudal bupivacaine and bupivacaine-tramadol for postoperative analgesia in children with hypospadias repair.
Topics: Anesthesia, Caudal; Anesthetics, Local; Bupivacaine; Child, Preschool; Drug Therapy, Combination; Hu | 2008 |
Efficacy of a low-dose spinal morphine with bupivacaine for postoperative analgesia in children undergoing hypospadias repair.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Child; Child, P | 2009 |
Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; D | 2002 |
Caudal bupivacaine supplemented with caudal or intravenous clonidine in children undergoing hypospadias repair: a double-blind study.
Topics: Adrenergic alpha-Agonists; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Anesthetics, Local; | 2004 |
A comparison of epidural bupivacaine, levobupivacaine, and ropivacaine on postoperative analgesia and motor blockade.
Topics: Amides; Analgesia, Epidural; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Dose-Response | 2004 |
Evaluation of adding preoperative or postoperative rectal paracetamol to caudal bupivacaine for postoperative analgesia in children.
Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Anesthesia, Caudal; Anesthetics, Lo | 2004 |
Presurgical analgesia in children subjected to hypospadias repair.
Topics: Analgesia, Epidural; Bupivacaine; Child; Child, Preschool; Double-Blind Method; Hemodynamics; Humans | 1993 |
Comparison of caudal bupivacaine and diamorphine with caudal bupivacaine alone for repair of hypospadias.
Topics: Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Consciousness; Drug Th | 1996 |
Penile block timing for postoperative analgesia of hypospadias repair in children.
Topics: Analgesia; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Humans; Hypospadias; Infant; Ma | 1997 |
Caudal tramadol for postoperative analgesia in pediatric hypospadias surgery.
Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child, Preschool; Drug The | 1997 |
Comparison of caudal tramadol vs bupivacaine for post-operative analgesia in children undergoing hypospadias surgery.
Topics: Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Double-Blind Method; H | 1999 |
The influence of sufentanil and/or clonidine on the duration of analgesia after a caudal block for hypospadias repair surgery in children.
Topics: Adolescent; Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthesia, Caudal; Anesthetics, Local; B | 2000 |
Ropivacaine undergoes slower systemic absorption from the caudal epidural space in children than bupivacaine.
Topics: Absorption; Amides; Anesthesia, Caudal; Anesthesia, General; Anesthetics, Local; Bupivacaine; Child; | 2002 |
Prospective to a randomized double-blind controlled trial to assess efficacy of double caudal analgesia in hypospadias repair.
Topics: Analgesia; Anesthesia, Caudal; Bupivacaine; Cohort Studies; Double-Blind Method; Humans; Hypospadias | 2002 |
Adequacy of caudal analgesia in children after penoscrotal and inguinal surgery using 0.5 or 1.0 ml.kg-1 bupivacaine 0.125%.
Topics: Analgesia, Epidural; Bupivacaine; Child; Child, Preschool; Circumcision, Male; Double-Blind Method; | 1992 |
Caudal epidural anesthesia reduces blood loss during hypospadias repair.
Topics: Anesthesia, Caudal; Anesthesia, Epidural; Anesthesia, Inhalation; Bupivacaine; Child, Preschool; Hal | 1990 |
12 other studies available for bupivacaine and Hypospadias
| Article | Year |
|---|---|
The association between caudal anesthesia and increased risk of postoperative surgical complications in boys undergoing hypospadias repair: Comment on data sparsity.
Topics: Anesthesia, Caudal; Bupivacaine; Humans; Hypospadias; Infant; Male; Postoperative Complications; Pos | 2017 |
Judging causal associations in observational research on caudal anesthesia and hypospadias repair.
Topics: Anesthesia, Caudal; Bupivacaine; Humans; Hypospadias; Male; Urethra; Urinary Fistula | 2017 |
Re: Pudendal versus Caudal Block in Children Undergoing Hypospadias Surgery: A Randomized Controlled Trial.
Topics: Bupivacaine; Child; Humans; Hypospadias; Male; Pain, Postoperative | 2018 |
Do caudal blocks cause complications following hypospadias surgery in children?
Topics: Anesthetics, Local; Bupivacaine; Child; Humans; Hypospadias; Infant; Male; Pain, Postoperative; Post | 2016 |
Caudal anaesthesia safety for hypospadias repair.
Topics: Anesthesia, Caudal; Anesthetics, Local; Bupivacaine; Humans; Hypospadias; Infant; Male | 2016 |
Caudal anesthesia safety for hypospadias repair - a reply.
Topics: Anesthesia, Caudal; Bupivacaine; Humans; Hypospadias; Infant; Male; Postoperative Complications | 2016 |
Bupivacaine usage for post-operative bladder spasm.
Topics: Anesthetics, Local; Bupivacaine; Child; Female; Humans; Hypospadias; Male; Pain Measurement; Pain, P | 2004 |
Comparison of caudal bupivacaine and bupivacaine-tramadol for postoperative analgesia in children undergoing hypospadias surgery.
Topics: Analgesics, Opioid; Anesthesia, Caudal; Bupivacaine; Child; Child, Preschool; Humans; Hypospadias; M | 2009 |
Longer than expected-duration of caudal analgesia with two different doses of levobupivacaine in children undergoing hypospadias repair.
Topics: Anesthesia, Caudal; Anesthetics, Local; Bupivacaine; Child, Preschool; Humans; Hypospadias; Infant; | 2010 |
Caudal block for post-operative pain relief in children after genital operations. A comparison between bupivacaine and morphine.
Topics: Anesthesia, Caudal; Anesthesia, Epidural; Bupivacaine; Child; Child, Preschool; Circumcision, Male; | 1981 |
An alternative block for post circumcision analgesia.
Topics: Adolescent; Adult; Aged; Bupivacaine; Child; Child, Preschool; Circumcision, Male; Humans; Hypospadi | 1977 |
Postoperative analgesia in children who have genito-urinary surgery. A comparison between caudal buprenorphine and bupivacaine.
Topics: Analgesia; Bupivacaine; Buprenorphine; Child; Child, Preschool; Circumcision, Male; Female; Humans; | 1990 |