bupivacaine has been researched along with Hypesthesia in 19 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Hypesthesia: Absent or reduced sensitivity to cutaneous stimulation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Postoperative pain is common in hemorrhoidectomy patients." | 3.11 | Pudendal Nerve Block for Posthemorrhoidectomy Pain: A Prospective, Single-Blinded Randomized Control Trial. ( An, V; Chandra, R; Chua, JYJ; Keck, JO; Lam, D; Steen, CJ, 2022) |
| "The time until the numbness wore off was 37 vs 21 hours (mean difference = 16 hours, 95% CI = 8 to 23)." | 2.94 | Extended Perineural Analgesia After Hip and Knee Replacement When Buprenorphine-Clonidine-Dexamethasone Is Added to Bupivacaine: Preliminary Report from a Randomized Clinical Trial. ( Ezaru, CS; Gilbert, KL; Ibinson, JW; Mikolic, JM; Muluk, VS; Paiste, HJ; Piva, SR; Rakesh, HR; Ritter, ME; Williams, BA, 2020) |
| "Patients recorded their level of numbness, pain, and medication use the night of the appointment and over the next 5 days." | 2.82 | Does Liposomal Bupivacaine (Exparel) Significantly Reduce Postoperative Pain/Numbness in Symptomatic Teeth with a Diagnosis of Necrosis? A Prospective, Randomized, Double-blind Trial. ( Beck, M; Drum, M; Fowler, S; Glenn, B; Nusstein, J; Reader, A, 2016) |
| " Primary outcome measures were safety and adverse events associated with NeoSTX." | 2.80 | A Phase 1, Dose-escalation, Double-blind, Block-randomized, Controlled Trial of Safety and Efficacy of Neosaxitoxin Alone and in Combination with 0.2% Bupivacaine, with and without Epinephrine, for Cutaneous Anesthesia. ( Alexander, ME; Berde, CB; Bilge, A; Boretsky, K; Cornelissen, L; Cravero, J; Donado, C; Kellogg, M; Kim, J; Kurgansky, KE; Lobo, K; McCann, ME; Ortiz, R; Peake, RW; Peyton, J; Zurakowski, D, 2015) |
| "Persistent pain after breast cancer surgery (PPBCS) affects 25 - 60% of breast cancer survivors and damage to the intercostobrachial nerve (ICBN) has been implicated as the cause of this predominantly neuropathic pain." | 1.43 | Ultrasound Guided Intercostobrachial Nerve Blockade in Patients with Persistent Pain after Breast Cancer Surgery: A Pilot Study. ( Andersen, KG; Anderson, KG; Duriaud, HM; Kehlet, H; Wijayasinghe, N, 2016) |
| "The numb chin syndrome is a rare manifestation of intractable pain in the palliative care setting and represents a major therapeutic challenge." | 1.43 | Spontaneous Osteonecrosis of the Jaw During Bisphosphonate Therapy: An Unusual Etiology of the Numb Chin Syndrome. ( Bardelli, D; Fusi-Schmidhauser, T, 2016) |
| "Seven patients developed hypesthesia in the blocked nerve distribution lasting from 1 week to 4 months." | 1.27 | Neuropathy after bupivacaine (Marcaine) wrist and metacarpal nerve blocks. ( Born, G, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 8 (42.11) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Steen, CJ | 1 |
| Lam, D | 1 |
| Chandra, R | 1 |
| Chua, JYJ | 1 |
| An, V | 1 |
| Keck, JO | 1 |
| Williams, BA | 1 |
| Ibinson, JW | 1 |
| Ritter, ME | 1 |
| Ezaru, CS | 1 |
| Rakesh, HR | 1 |
| Paiste, HJ | 1 |
| Gilbert, KL | 1 |
| Mikolic, JM | 1 |
| Muluk, VS | 1 |
| Piva, SR | 1 |
| Mont, MA | 1 |
| Beaver, WB | 1 |
| Dysart, SH | 1 |
| Barrington, JW | 1 |
| Del Gaizo, DJ | 1 |
| Calder, K | 1 |
| Chung, B | 1 |
| O'Brien, C | 1 |
| Lalonde, DH | 1 |
| Lobo, K | 1 |
| Donado, C | 1 |
| Cornelissen, L | 1 |
| Kim, J | 1 |
| Ortiz, R | 1 |
| Peake, RW | 1 |
| Kellogg, M | 1 |
| Alexander, ME | 1 |
| Zurakowski, D | 1 |
| Kurgansky, KE | 1 |
| Peyton, J | 1 |
| Bilge, A | 1 |
| Boretsky, K | 1 |
| McCann, ME | 1 |
| Berde, CB | 1 |
| Cravero, J | 1 |
| Wijayasinghe, N | 1 |
| Duriaud, HM | 1 |
| Kehlet, H | 1 |
| Andersen, KG | 1 |
| Anderson, KG | 1 |
| Glenn, B | 1 |
| Drum, M | 1 |
| Reader, A | 1 |
| Fowler, S | 1 |
| Nusstein, J | 1 |
| Beck, M | 1 |
| Gross, H | 1 |
| Fusi-Schmidhauser, T | 1 |
| Bardelli, D | 1 |
| Gozdemir, M | 1 |
| Muslu, B | 1 |
| Sert, H | 1 |
| Usta, B | 1 |
| Demircioglu, RI | 1 |
| Karatas, OF | 1 |
| Surgit, O | 1 |
| Nayyar, MS | 1 |
| Yates, C | 1 |
| Branco, FP | 1 |
| Ranali, J | 1 |
| Ambrosano, GM | 1 |
| Volpato, MC | 1 |
| Rabadán Díaz, JV | 1 |
| López Moreno, JA | 1 |
| Soria Quiles, A | 1 |
| Del Pino Moreno, AL | 1 |
| Rees, SG | 1 |
| Collis, RE | 1 |
| Dickson, DR | 1 |
| Thornton, DJ | 1 |
| Born, G | 1 |
| Hampl, KF | 1 |
| Schneider, MC | 1 |
| Ummenhofer, W | 1 |
| Drewe, J | 1 |
| Goulden, V | 1 |
| Toomey, PJ | 1 |
| Highet, AS | 1 |
| Atchabahian, A | 1 |
| Brown, AR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Comparative Study of Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative Analgesia in Perianal Surgery[NCT05990569] | 60 participants (Anticipated) | Interventional | 2023-08-12 | Recruiting | |||
| The Efficacy of Local Infiltration Analgesia for Postoperative Pain Management and Functional Recovery After Total Knee Arthroplasty: Peripheral Nerve Blocks With and Without Local Infiltration Analgesia[NCT04258241] | 80 participants (Anticipated) | Interventional | 2020-03-06 | Recruiting | |||
| Impact of Integrated Care Pathways for Prevention of Post-operative Urinary Retention in Primary Total Knee or Total Hip Replacement: Prospective Randomized Control Trial[NCT03863743] | 164 participants (Anticipated) | Interventional | 2019-02-05 | Recruiting | |||
| Pain Outcomes Following Hip Arthroscopy: A Prospective Randomized Control Study Comparing Fascia Iliaca Blockade vs Extracapsular Local Field Infiltration With Liposomal Bupivacaine[NCT04114058] | Phase 4 | 37 participants (Actual) | Interventional | 2019-10-29 | Completed | ||
| Preemptive Local Analgesia With Liposomal Bupivacaine in Vaginal Hysterectomy: A Randomized Controlled Study[NCT03907033] | Phase 4 | 28 participants (Actual) | Interventional | 2019-09-03 | Terminated (stopped due to Insufficient funding to continue with study activities) | ||
| A Multicenter, Randomized, Double-Blind, Controlled Trial Comparing Local Infiltration Analgesia With EXPAREL to Local Infiltration Analgesia Without EXPAREL to Manage Postsurgical Pain Following Total Knee Arthroplasty[NCT02713490] | Phase 4 | 140 participants (Actual) | Interventional | 2016-04-18 | Completed | ||
| Assessment of the Operative Course in Connection With Removal of Lower Third Molars With Particular Consideration to the Occurence of Pain and Swelling[NCT00805298] | 154 participants (Actual) | Interventional | 2008-08-31 | Completed | |||
| MORphine Use in the Fascia Iliaca Compartment Block With UltraSound[NCT03846102] | Phase 4 | 55 participants (Actual) | Interventional | 2019-01-28 | Terminated (stopped due to COVID-19 crisis.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Record of number of narcotic pain pills utilized by patients . This was reported as a total from post op day 1 to 4. The number listed is an average from each patient, from the total pills taken at home. (NCT04114058)
Timeframe: total pill taken over the course of days 1-4 post op.
| Intervention | number of pills (Mean) |
|---|---|
| Liposomal Bupivicaine | 7.6 |
| Fascia Iliaca Blockade | 7.8 |
number of falls occurring at home after discharge. This is the total number of falls of all patients in each group, over the first 7 days post op. This is not reported as a mean. (NCT04114058)
Timeframe: Post op days 1-7
| Intervention | total number of falls (Number) |
|---|---|
| Liposomal Bupivicaine | 0 |
| Fascia Iliaca Blockade | 6 |
pain scale Questionnaire 0 equals no pain at all and 10 equals the worst. The out come measure time frame is reported as the average VAS score of the first 4 day post op. (NCT04114058)
Timeframe: post op days 1-4 (Average VAS score of first 4 days of post op)
| Intervention | cm (Mean) |
|---|---|
| Liposomal Bupivicaine | 2.4 |
| Fascia Iliaca Blockade | 2.7 |
Number of patients who had post-void residual (PVR) >150cc's at voiding trial prior to discharge (NCT03907033)
Timeframe: At voiding trial prior to discharge from hospital, approximately 72 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Standard Bupivacaine | 1 |
| Liposomal Bupivacaine | 1 |
Number of times the patient vomited (NCT03907033)
Timeframe: 24, 48, and 72 hours post-surgery
| Intervention | events (Median) | ||
|---|---|---|---|
| 24 hours post-surgery | 48 hours post-surgery | 72 hours post-surgery | |
| Liposomal Bupivacaine | 0.0 | 0.0 | 0.0 |
| Standard Bupivacaine | 0.0 | 0.0 | 0.0 |
Number of times patient reported feeling nauseous (NCT03907033)
Timeframe: 24, 48, and 72 hours post-surgery
| Intervention | events (Median) | ||
|---|---|---|---|
| 24 hours post-surgery | 48 hours post-surgery | 72 hours post-surgery | |
| Liposomal Bupivacaine | 0.0 | 0.0 | 0.0 |
| Standard Bupivacaine | 0.0 | 0.0 | 0.0 |
Assessed on 0-10 scale (0 being worst level of satisfaction, 10 being best level) (NCT03907033)
Timeframe: 72 hours and 7-10 days post surgery
| Intervention | score on a scale (Median) | |
|---|---|---|
| 72 hours post-surgery | 7-10 days post-surgery | |
| Liposomal Bupivacaine | 9.5 | 9.0 |
| Standard Bupivacaine | 10.0 | 10.00 |
Participants post-surgical analgesic medication use of Ibuprofen and acetaminophen measured in milligrams (mg) (NCT03907033)
Timeframe: First 72 hours following surgery completion
| Intervention | mg (Median) | |
|---|---|---|
| Ibuprofen | Tylenol | |
| Liposomal Bupivacaine | 4800.0 | 6500.0 |
| Standard Bupivacaine | 5400.0 | 6500.0 |
Participants post-surgical analgesic medication use of IV hydrocodone and oxycodone measured in morphine equivalents (ME) (NCT03907033)
Timeframe: First 72 hours following surgery completion
| Intervention | Morphine Equivalents (ME) (Median) | |
|---|---|---|
| Hydrocodone | Oxycodone | |
| Liposomal Bupivacaine | 0 | 30.0 |
| Standard Bupivacaine | 0 | 30.0 |
Scale Ranges from 0 (no pain) to 10 (extreme pain) (NCT03907033)
Timeframe: 24, 48, and 72 hours post-surgery completion
| Intervention | score on a scale (Median) | ||
|---|---|---|---|
| 24 hours post-surgery | 48 hours post-surgery | 72 hours post-surgery | |
| Liposomal Bupivacaine | 3.5 | 3.6 | 2.4 |
| Standard Bupivacaine | 3.1 | 2.5 | 1.6 |
"AUC of VAS pain intensity scores from 12 to 48 hours, which represents total pain experienced from 12 to 48 hours. Visual Analog Scale (VAS) is a pain scale. The VAS was presented as a straight 10 cm line, where 0 cm is no pain and 10 cm is the worst pain possible. Patients were asked, How much pain are you experiencing right now? Please place a vertical mark on the line below to indicate the level of pain you are experiencing right now." (NCT02713490)
Timeframe: From 12-48 hours
| Intervention | cm*hr (Least Squares Mean) |
|---|---|
| EXPAREL | 181.523 |
| Bupivacaine | 208.407 |
"The overall benefit of analgesic score (OBAS) comprises seven questions to assess pain intensity, adverse effects, and patients' satisfaction with analgesia (eg, Please rate your current pain at rest on a scale between 0=minimal pain and 4=maximum imaginable pain). Overall scores ranged between 0- 28. OBAS measures patients' benefit from postoperative pain therapy. A lower composite score indicates greater benefit from the therapy." (NCT02713490)
Timeframe: 48 hours
| Intervention | score on a scale (Mean) |
|---|---|
| EXPAREL | 4.1 |
| Bupivacaine | 4.6 |
(NCT02713490)
Timeframe: 48 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| EXPAREL | 7 |
| Bupivacaine | 0 |
Total postsurgical opioid consumption (converted to oral morphine equivalents) through 48 hours (NCT02713490)
Timeframe: 0-48 hours
| Intervention | mg (Least Squares Mean) |
|---|---|
| EXPAREL | 16.321 |
| Bupivacaine | 80.328 |
Time to first opioid rescue was estimated from Kaplan-Meier analysis and presented as quartiles (ie, time to rescue for the first 25% / 50% / 75% of subjects within each treatment group). (NCT02713490)
Timeframe: 48 hours
| Intervention | h (Number) | ||
|---|---|---|---|
| First quartile | Median quartile | Third quartile | |
| Bupivacaine | 1.00 | 2.917 | 7.200 |
| EXPAREL | 2.617 | 4.125 | 9.667 |
11 trials available for bupivacaine and Hypesthesia
| Article | Year |
|---|---|
Pudendal Nerve Block for Posthemorrhoidectomy Pain: A Prospective, Single-Blinded Randomized Control Trial.
Topics: Analgesics, Opioid; Anesthetics, Local; Australia; Bupivacaine; Humans; Hypesthesia; Pain, Postopera | 2022 |
Extended Perineural Analgesia After Hip and Knee Replacement When Buprenorphine-Clonidine-Dexamethasone Is Added to Bupivacaine: Preliminary Report from a Randomized Clinical Trial.
Topics: Analgesia; Anesthetics, Local; Bupivacaine; Buprenorphine; Clonidine; Dexamethasone; Double-Blind Me | 2020 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Local Infiltration Analgesia With Liposomal Bupivacaine Improves Pain Scores and Reduces Opioid Use After Total Knee Arthroplasty: Results of a Randomized Controlled Trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Area Under Curve; Arthroplasty, Replacement | 2018 |
Bupivacaine digital blocks: how long is the pain relief and temperature elevation?
Topics: Acute Pain; Adult; Anesthetics, Local; Body Temperature; Bupivacaine; Epinephrine; Female; Fingers; | 2013 |
A Phase 1, Dose-escalation, Double-blind, Block-randomized, Controlled Trial of Safety and Efficacy of Neosaxitoxin Alone and in Combination with 0.2% Bupivacaine, with and without Epinephrine, for Cutaneous Anesthesia.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Dose-Response Relationship, Drug; Double- | 2015 |
Does Liposomal Bupivacaine (Exparel) Significantly Reduce Postoperative Pain/Numbness in Symptomatic Teeth with a Diagnosis of Necrosis? A Prospective, Randomized, Double-blind Trial.
Topics: Adult; Anesthetics, Local; Bupivacaine; Delayed-Action Preparations; Dental Pulp Necrosis; Double-Bl | 2016 |
[Not Available].
Topics: Adult; Anesthesia, Local; Bupivacaine; Dose-Response Relationship, Drug; Double-Blind Method; Drug T | 2016 |
Transient neurological symptoms after spinal anaesthesia with levobupivacaine 5 mg/ml or lidocaine 20 mg/ml.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Double-Blind Me | 2010 |
Bupivacaine as pre-emptive analgesia in third molar surgery: Randomised controlled trial.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Local; Bupivacaine; Female; Follow-Up Studies; H | 2006 |
A double-blind comparison of 0.5% bupivacaine with 1:200,000 epinephrine and 0.5% levobupivacaine with 1:200,000 epinephrine for the inferior alveolar nerve block.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Local; Bupivacaine; Cross-Over Studies; Dental P | 2006 |
Transient neurologic symptoms after spinal anesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivacain | 1995 |
8 other studies available for bupivacaine and Hypesthesia
| Article | Year |
|---|---|
Ultrasound Guided Intercostobrachial Nerve Blockade in Patients with Persistent Pain after Breast Cancer Surgery: A Pilot Study.
Topics: Adult; Aged; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Denmark; Double-Blind Method; Female | 2016 |
Spontaneous Osteonecrosis of the Jaw During Bisphosphonate Therapy: An Unusual Etiology of the Numb Chin Syndrome.
Topics: Aged; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Bupivaca | 2016 |
[Neurological deficit during recovery from cesarean section under spinal anesthesia after the appearance of undiagnosed multiple sclerosis].
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Sectio | 2006 |
Spinal cord injury after accidental dural puncture for labour analgesia.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Intravenous; Anesthetics, Local; Ba | 2007 |
A postoperative cup of tea--the patient's best friend?
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Burns; Carpal | 2007 |
Neuropathy after bupivacaine (Marcaine) wrist and metacarpal nerve blocks.
Topics: Adult; Bupivacaine; Female; Fingers; Humans; Hypesthesia; Male; Metacarpus; Middle Aged; Nerve Block | 1984 |
Successful treatment of notalgia paresthetica with a paravertebral local anesthetic block.
Topics: Adult; Anesthetics, Local; Back Pain; Bupivacaine; Female; Follow-Up Studies; Humans; Hypesthesia; N | 1998 |
Postoperative neuropathy following fascia iliaca compartment blockade.
Topics: Aged; Anesthesia, Spinal; Arthroplasty, Replacement, Hip; Bupivacaine; Female; Femoral Nerve; Humans | 2001 |