bupivacaine has been researched along with Hypertrophy, Left Ventricular in 2 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Hypertrophy, Left Ventricular: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Local anesthetics, particularly potent long acting ones such as bupivacaine, can cause cardiotoxicity by inhibiting sodium ion channels; however, the impact of left ventricular hypertrophy on the cardiotoxicity and the underlying mechanisms remain undetermined." | 7.96 | Left Ventricular Hypertrophy Increases Susceptibility to Bupivacaine-induced Cardiotoxicity through Overexpression of Transient Receptor Potential Canonical Channels in Rats. ( Hino, H; Hori, K; Kuno, M; Matsuura, T; Mori, T; Nishikawa, K; Tsujikawa, S, 2020) |
| "Local anesthetics, particularly potent long acting ones such as bupivacaine, can cause cardiotoxicity by inhibiting sodium ion channels; however, the impact of left ventricular hypertrophy on the cardiotoxicity and the underlying mechanisms remain undetermined." | 3.96 | Left Ventricular Hypertrophy Increases Susceptibility to Bupivacaine-induced Cardiotoxicity through Overexpression of Transient Receptor Potential Canonical Channels in Rats. ( Hino, H; Hori, K; Kuno, M; Matsuura, T; Mori, T; Nishikawa, K; Tsujikawa, S, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hino, H | 1 |
| Matsuura, T | 1 |
| Kuno, M | 1 |
| Hori, K | 1 |
| Tsujikawa, S | 1 |
| Mori, T | 1 |
| Nishikawa, K | 1 |
| Fuzier, R | 1 |
| Murat, O | 1 |
| Gilbert, ML | 1 |
| Maguès, JP | 1 |
| Fourcade, O | 1 |
2 other studies available for bupivacaine and Hypertrophy, Left Ventricular
| Article | Year |
|---|---|
Left Ventricular Hypertrophy Increases Susceptibility to Bupivacaine-induced Cardiotoxicity through Overexpression of Transient Receptor Potential Canonical Channels in Rats.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiotoxins; Gene Expression; HEK293 Cells; Humans; Hyper | 2020 |
[Continuous spinal anesthesia for femoral fracture in two patients with severe aortic stenosis].
Topics: Aged, 80 and over; Anesthesia, Spinal; Aortic Valve Stenosis; Arthroplasty, Replacement, Hip; Bone N | 2006 |