bupivacaine has been researched along with Hyperkalemia in 6 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Hyperkalemia: Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intraventricular conduction disorders and reentrant arrhythmias in dogs can be produced by high plasma bupivacaine concentrations." | 7.68 | Enhancement by hyponatremia and hyperkalemia of ventricular conduction and rhythm disorders caused by bupivacaine. ( Bertix, L; Couzon, P; Faucon, G; Freysz, M; Mazze, R; Timour, Q, 1990) |
| "Intraventricular conduction disorders and reentrant arrhythmias in dogs can be produced by high plasma bupivacaine concentrations." | 3.68 | Enhancement by hyponatremia and hyperkalemia of ventricular conduction and rhythm disorders caused by bupivacaine. ( Bertix, L; Couzon, P; Faucon, G; Freysz, M; Mazze, R; Timour, Q, 1990) |
| "The influence of hyperkalemia on the central nervous system and cardiac toxicity of bupivacaine and lidocaine was studied in open-chested mechanically ventilated dogs." | 3.67 | The influence of serum potassium on the cerebral and cardiac toxicity of bupivacaine and lidocaine. ( Avery, P; Redon, D; Rusy, B; Schaenzer, G, 1984) |
| "Bradycardia and hypotension were the first major signs of toxicity from a 250 mg bupivacaine axillary brachial plexus block experienced by a patient with chronic renal failure, who had an anion gap acidosis and hyperkalaemia." | 3.66 | Bupivacaine cardiotoxicity in a patient with renal failure. ( Aldrete, JA; Gould, DB, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Avery, P | 1 |
| Redon, D | 1 |
| Schaenzer, G | 1 |
| Rusy, B | 1 |
| Gould, DB | 1 |
| Aldrete, JA | 1 |
| Komai, H | 1 |
| Rusy, BF | 1 |
| Moore, DC | 2 |
| Timour, Q | 1 |
| Freysz, M | 1 |
| Mazze, R | 1 |
| Couzon, P | 1 |
| Bertix, L | 1 |
| Faucon, G | 1 |
| Bridenbaugh, LD | 1 |
6 other studies available for bupivacaine and Hyperkalemia
| Article | Year |
|---|---|
The influence of serum potassium on the cerebral and cardiac toxicity of bupivacaine and lidocaine.
Topics: Animals; Bupivacaine; Cardiac Output; Dogs; Electrocardiography; Electroencephalography; Female; Hea | 1984 |
Bupivacaine cardiotoxicity in a patient with renal failure.
Topics: Acidosis; Brachial Plexus; Bradycardia; Bupivacaine; Heart; Humans; Hyperkalemia; Hypotension; Kidne | 1983 |
Effects of bupivacaine and lidocaine on AV conduction in the isolated rat heart: modification by hyperkalemia.
Topics: Animals; Atrioventricular Node; Bupivacaine; Drug Synergism; Female; Heart Conduction System; Hyperk | 1981 |
If ventricular conduction and rhythm disorders are caused by bupivacaine, it is doubtful that intraoperative hyponatremia and hyperkalemia enhance them.
Topics: Animals; Arrhythmias, Cardiac; Bupivacaine; Humans; Hyperkalemia; Hyponatremia; Intraoperative Perio | 1991 |
Enhancement by hyponatremia and hyperkalemia of ventricular conduction and rhythm disorders caused by bupivacaine.
Topics: Animals; Arrhythmias, Cardiac; Bupivacaine; Dogs; Electrocardiography; Female; Glycine; Heart Conduc | 1990 |
Does hyperkalemia contraindicate the use of bupivacaine or the use of succinylcholine to treat bupivacaine-induced toxicity in humans?
Topics: Arteriovenous Shunt, Surgical; Brachial Plexus; Bupivacaine; Heart; Humans; Hyperkalemia; Nerve Bloc | 1985 |