bupivacaine and Hallux Valgus

bupivacaine has been researched along with Hallux Valgus in 14 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Hallux Valgus: Lateral displacement of the great toe (HALLUX), producing deformity of the first METATARSOPHALANGEAL JOINT with callous, bursa, or BUNION formation over the bony prominence.

Research

Studies (14)

Authors

Clinical Trials (9)

Trial Overview

Trial Outcomes

Pain Levels on a Visual Analog Scale ( VAS)

A Visual Analog Scale (VAS) ranging from 0 to 10 in increments of 1 was used to both qualitatively and quantitatively assess the level and severity of pain during the time points ranging from the immediate post-operative period through 72 hours post-operative. Each number on the scale is accompanied by a visual facial expression that indicates the level of pain, discomfort, and distress appropriate to the number on the scale. The more severe the level of pain, the higher the corresponding number and more distressing the accompanying facial expression. A VAS score of 0 indicates no active pain level and is accompanied by a pleasantly smiling face whereas a VAS score of 10 indicates the most severe active pain level and is accompanied by a visibly-distraught face that is frowning, grimacing, and sweating. The combination of facial expressions and numbers is supposed to provide a language-independent, validated means of assessing pain levels. (NCT02480621)
Timeframe: Immediate post-operative period until 72 hours post-operatively

Hospital Readmission

Readmission to hospital will be noted (NCT03270514)
Timeframe: From end of surgery assessed up to 30 days post-operatively

Mortality

Mortality will be noted at specific timepoints (NCT03270514)
Timeframe: From end of surgery assessed up to 30 days post-operatively

Non-invasive Ventilation (NIV) Requirement

Episodes of NIV such as upper airway masks or similar devices will be quantified (NCT03270514)
Timeframe: From time of end of surgery to 72 hours post-operatively or until hospital discharge

Patient Satisfaction

Patient will give an assessment regarding pain management on a scale of 0 - 10 with 0 indicating the lowest satisfaction with pain management and 10 indicating the highest satisfaction with pain management (NCT03270514)
Timeframe: Given at the time of discharge up to 30 days post-operatively

Patient Time to Mobilization

The time it takes until patient ambulates will be measured (NCT03270514)
Timeframe: From time of end of surgery to time of mobilization up to 72 hours or discharge, *assessed up to 120 hours*

Patient Time to Oral Intake

The time it takes until the patient is able to/medically cleared to consume food or liquid will be measured (NCT03270514)
Timeframe: From time of end of surgery to time of oral intake up to 72 hours post-operatively or until hospital discharge

Patient Time to Out of Bed to Chair

The time it takes until the patient advances from bedrest to out of bed (OOB) to chair will be measured (NCT03270514)
Timeframe: From time of end of surgery to time of mobilization up to 72 hours post-operatively

Post-operative Nausea and Vomiting

Whether a patient experiences at least one episode of nausea and emesis will be measured (NCT03270514)
Timeframe: From time of end of surgery to 72 hours post-operatively

Re-intubation

Instances of re-intubation will be recorded (NCT03270514)
Timeframe: From time of end of surgery to patient discharge up to one week

Time to Extubation

The time it takes until the patient is extubated post-operatively will be measured (NCT03270514)
Timeframe: From the end of surgery until the patient is extubated up to 72 hours post-operatively

Use of Incentive Spirometry

Frequency of incentive spirometry will be measured (NCT03270514)
Timeframe: From time of end of surgery to 72 hours post-operatively

Length of Hospital and ICU Stay

Length of both hospital and ICU stay will be measured (NCT03270514)
Timeframe: From date of surgery assessed up to 30 day post-operatively

Post-operative Pain Intensity

Postoperative pain scores evaluated by numeric rating scale or (NRS) where 0- no pain and 10- worst pain, at rest and at movement (NCT03270514)
Timeframe: NRS scores will be evaluated every 4 hours until 24 hours post-operatively, every 8 hours until 48 hours post-operatively, and every 12 hours for 72 hours post-operatively

Serum Cortisol Levels

Stress response suppression as a result of treatment will be evaluated by comparing hormone levels between the groups. Serum cortisol levels will be taken to measure this. (NCT03270514)
Timeframe: Measured 8, 48, and 72 hours post-operatively

Total Narcotic Consumption

All narcotics administered in the first 0-8, 8-24, 24-48, and 48-72 hours and the total narcotics administered in the 0-72 hours postoperative period(PCA narcotics, nurse-administered IV narcotics, and oral narcotics). All narcotics will be converted to total IV morphine equivalent for comparison between two groups. (NCT03270514)
Timeframe: 0-72 hours post-operative period

AM-PAC Score to Measure Patients Fitness for Discharge

AM-PAC (activity measure for post-acute care) will be used to determine if a patient is fit to discharge based on mobility with 6 being unable to mobilize up to 24 being independent. Patients who scored above 20 were considered fit to discharge. (NCT03303794)
Timeframe: Post-Operation Day 1

Opioid Consumption During the First 48 Hours After TKA Surgery

Monitor how much opioid patient consumes (NCT03303794)
Timeframe: During the first 48 hours after surgery

Pain Scores During 48 Hrs Postoperatively

Will use Numeric Pain Rating Scale (NPRS) to measure pain with 0 being no pain and 10 being the worst pain. (NCT03303794)
Timeframe: 48 hours postoperatively

Area Under the Curve (AUC) of the Numeric Rating Scale at Rest (NRS-R) Pain Intensity Scores

"The AUC of the NRS-R pain intensity scores from time 0 through 24 hours~The subject was to rest for at least 5 minutes before responding to the following question, On a scale of 0 to 10, where 0 = no pain and 10 = worst possible pain, how much pain are you having right now?" (NCT00890682)
Timeframe: 0-24 hours

Frequency of Postoperative Opioid Related Adverse Effects

Frequency of postoperative opioid related adverse effects within the first week of surgery will be recorded. This includes nausea, vomiting, pruritus, allergy, respiratory depression. (NCT03722927)
Timeframe: Postoperatively, 1 week

Length of Stay for Hospitalization

The length of stay for hospitalization after mastectomy and breast reconstruction will be recorded. (NCT03722927)
Timeframe: up to 47 Hours

Number of Morphine Doses Across All Subjects

This will be measured by the number of doses within the first month postoperatively and recorded on pain medication daily diary kept by subject. (NCT03722927)
Timeframe: 1 Month

Readmission Rates to the Hospital

Readmission rates to the hospital within 2 months after mastectomy and breast reconstruction will be recorded (NCT03722927)
Timeframe: Month 2

Mean Visual Analog Scores

This will be measured every 12 hours for the first 48 hours postoperatively by the level of breast pain associated with arm movements while eating on a scale of 0-10 with higher scores denoting worse outcomes. (NCT03722927)
Timeframe: 48 hours

Mean Visual Analog Scores

This will be measured every 12 hours for the first 48 hours postoperatively by the level of breast pain associated with arm movements while eating on a scale of 0-10 with higher scores denoting worse outcomes. (NCT03722927)
Timeframe: 48 hours

NRS Pain Score at 16 Hours

Pain scale (0-10), where 0 = no pain and 10 = worst pain imaginable (NCT02352922)
Timeframe: 16 hours post-op

NRS Pain Score at 2 Hours

numeric rating scale (0-10), mean and SD, where 0 = no pain and 10 = worst pain imaginable (NCT02352922)
Timeframe: 2 hours post-op

NRS Pain Score at 4 Hours

Pain scale measured from 0-10, where 0 = no pain and 10 = worst pain imaginable (NCT02352922)
Timeframe: 4 hours post-op

NRS Pain Score at 8 Hours

Pain scale (0-10), where 0 = no pain and 10 = worst pain imaginable (NCT02352922)
Timeframe: 8 hours post-op

NRS Pain Score Post-op Day 14

Pain scale (0-10), where 0 = no pain and 10 = worst pain imaginable (NCT02352922)
Timeframe: Post-Operative Day 14

NRS Pain Score Post-op Day 2

Pain scale (0-10), where 0 = no pain and 10 = worst pain imaginable (NCT02352922)
Timeframe: 2 days post-op

NRS Pain Score Post-op Day 3

Pain scale, where 0 = no pain and 10 = worst pain imaginable (NCT02352922)
Timeframe: 3 days post-op

Numerical Rating Scale (NRS) Post-operative Pain Score on Post-Operative Day 1 (POD1).

Numerical Rating Scale (0-10) post-operative pain score on POD1, where 0 = no pain and 10 = worst pain imaginable (NCT02352922)
Timeframe: 24 hours

Quality of Life as Measured by the Brief Pain Inventory (BPI)

at time of post-op visit The brief pain inventory scale uses the 0 to 10 numerical rating scale to measure pain intensity under four different conditions. On the four conditions 0 = no pain, no relief, and does not interfere, whereas 10 = pain as bad as you can imagine, complete relief, and completely interferes (NCT02352922)
Timeframe: Post-Operative Day 14

Quality of Life as Measured by the Brief Pain Inventory (BPI)

The brief pain inventory scale uses the 0 to 10 numerical rating scale to measure pain intensity under four different conditions. On the four conditions 0 = no pain, no relief, and does not interfere, whereas 10 = pain as bad as you can imagine, complete relief, and completely interferes (NCT02352922)
Timeframe: Post-Operative Day 2

Quality of Life as Measured by the Brief Pain Inventory (BPI)

The brief pain inventory scale uses the 0 to 10 numerical rating scale to measure pain intensity under four different conditions. On the four conditions 0 = no pain, no relief, and does not interfere, whereas 10 = pain as bad as you can imagine, complete relief, and completely interferes (NCT02352922)
Timeframe: Post-Operative Day 3

Total Opioid Use at Post-op Day 14

Total use of home opioids by pill count/ oral morphine equivalents (NCT02352922)
Timeframe: Post-Operative Day 14

Total Opioid Use End of Post-op Day 3

Total use of home opioids by pill count/ oral morphine equivalents (NCT02352922)
Timeframe: 72 hrs post-op

Total Opioid Use Prior to Hospital Discharge

Oral morphine equivalent of opioid use while in the hospital (NCT02352922)
Timeframe: 24 hours

Number of Participants With Adverse Events

(NCT02352922)
Timeframe: Post-Operative Day 14

Trials

12 trials available for bupivacaine and Hallux Valgus

Other Studies

2 other studies available for bupivacaine and Hallux Valgus