Page last updated: 2024-10-24

bupivacaine and Glaucoma

bupivacaine has been researched along with Glaucoma in 13 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Research Excerpts

ExcerptRelevanceReference
"To compare patient comfort and the efficacy of lidocaine 2% gel versus retrobulbar anaesthesia for Ahmed glaucoma implant surgery."9.11Comparison of lidocaine 2% gel versus retrobulbar anaesthesia for implantation of Ahmed glaucoma drainage. ( Alonso, N; Benatar, J; Corcostegui, J; Muñoz-Negrete, FJ; Rebolleda, G, 2005)
"To compare patient comfort and the efficacy of lidocaine 2% gel versus retrobulbar anaesthesia for Ahmed glaucoma implant surgery."5.11Comparison of lidocaine 2% gel versus retrobulbar anaesthesia for implantation of Ahmed glaucoma drainage. ( Alonso, N; Benatar, J; Corcostegui, J; Muñoz-Negrete, FJ; Rebolleda, G, 2005)
"After a retro-bulbar block for glaucoma surgery, a 60-year-old man developed loss of consciousness, apnea with hypotension and bradycardia-features of brainstem anesthesia."3.83Brainstem Anesthesia after Retrobulbar Block: A Case Report and Review of Literature. ( Gebreal, GW; Tolesa, K, 2016)
"Pain was scored subjectively by each patient (0-10) during the injection, peroperatively and postoperatively."2.70[Comparison between Greenbaum's parabulbar anesthesia and Ripart's subtenon anesthesia in the anterior segment surgery]. ( Alberti, M; Baltenneck, A; Batisse, JL; de la Marnierre, E; Mage, F, 2002)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's2 (15.38)18.2507
2000's6 (46.15)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tolesa, K1
Gebreal, GW1
Theventhiran, A1
Shabsigh, M1
De Moraes, CG1
Cioffi, GA1
Kamel, M1
Blumberg, D1
Al-Aswad, LA1
Sarchahi, AA1
Eskandari, M1
Sykes, OT1
Presland, A1
Zabriskie, NA1
Ahmed, II1
Crandall, AS1
Daines, B1
Burns, TA1
Patel, BC1
Pablo, LE1
Ferreras, A1
Pérez-Oliván, S1
Larrosa, JM1
Gómez, ML1
Honrubia, FM1
Rebolleda, G1
Muñoz-Negrete, FJ1
Benatar, J1
Corcostegui, J1
Alonso, N1
Parrish, RK1
Spaeth, GL1
Poryzees, EM1
Hargens, CW1
Azuara-Blanco, A1
Moster, MR1
Marr, BP1
Ghanchi, FD1
Khan, MY1
Kallio, H1
Paloheimo, M1
Maunuksela, EL1
de la Marnierre, E1
Mage, F1
Alberti, M1
Batisse, JL1
Baltenneck, A1
Laaka, V1
Nikki, P1
Tarkkanen, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Application of Recombinant Human Hyaluronidase is Effective for the Use of Local Blocks for Eyelid Surgery[NCT02059694]0 participants (Actual)InterventionalWithdrawn
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

9 trials available for bupivacaine and Glaucoma

ArticleYear
A comparison of topical and retrobulbar anesthesia for trabeculectomy.
    Journal of glaucoma, 2002, Volume: 11, Issue:4

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine;

2002
Contact-topical plus intracameral lidocaine versus peribulbar anesthesia in combined surgery: a randomized clinical trial.
    Journal of glaucoma, 2004, Volume: 13, Issue:6

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthesia; Anesthetics, Local; Bupivacaine; Catar

2004
Comparison of lidocaine 2% gel versus retrobulbar anaesthesia for implantation of Ahmed glaucoma drainage.
    Acta ophthalmologica Scandinavica, 2005, Volume: 83, Issue:2

    Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Female; Gels; Glauc

2005
Evaluation of local anesthesia agents using a new force-sensitive lid speculum.
    Ophthalmic surgery, 1983, Volume: 14, Issue:7

    Topics: Anesthetics, Local; Bupivacaine; Facial Nerve; Glaucoma; Humans; Lidocaine; Mepivacaine; Random Allo

1983
Subconjunctival versus peribulbar anesthesia in trabeculectomy: a prospective, randomized study.
    Ophthalmic surgery and lasers, 1997, Volume: 28, Issue:11

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Conjunctiva; Drug Combinations; Eye Moveme

1997
Sublingual lorazepam as premedication in peribulbar anesthesia.
    Journal of cataract and refractive surgery, 1997, Volume: 23, Issue:10

    Topics: Administration, Sublingual; Aged; Aged, 80 and over; Analgesia; Anesthesia, Local; Anesthetics, Loca

1997
Hyaluronidase as an adjuvant in bupivacaine-lidocaine mixture for retrobulbar/peribulbar block.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine;

2000
[Comparison between Greenbaum's parabulbar anesthesia and Ripart's subtenon anesthesia in the anterior segment surgery].
    Journal francais d'ophtalmologie, 2002, Volume: 25, Issue:2

    Topics: Anesthesia, Local; Anesthetics, Local; Anterior Eye Segment; Bupivacaine; Glaucoma; Humans; Lidocain

2002
Comparison of bupivacaine with and without adrenalin and mepivacaine with adrenalin in intraocular surgery.
    Acta ophthalmologica, 1972, Volume: 50, Issue:2

    Topics: Aged; Anesthetics, Local; Bupivacaine; Cataract Extraction; Drug Combinations; Epinephrine; Female;

1972

Other Studies

4 other studies available for bupivacaine and Glaucoma

ArticleYear
Brainstem Anesthesia after Retrobulbar Block: A Case Report and Review of Literature.
    Ethiopian journal of health sciences, 2016, Volume: 26, Issue:6

    Topics: Anesthetics, Local; Apnea; Brain Stem; Bupivacaine; Glaucoma; Humans; Hypotension; Male; Middle Aged

2016
A Comparison of Retrobulbar Versus Topical Anesthesia in Trabeculectomy and Aqueous Shunt Surgery.
    Journal of glaucoma, 2018, Volume: 27, Issue:1

    Topics: Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Cohort Studies; Eye

2018
Effect of four local anesthetics (tetracaine, proparacaine, lidocaine, and bupivacaine) on intraocular pressure in dogs.
    International ophthalmology, 2019, Volume: 39, Issue:7

    Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Disease Models

2019
Trabeculectomy postponed due to volume of sub-Tenon local anaesthetic.
    Anaesthesia, 2009, Volume: 64, Issue:1

    Topics: Anesthetics, Local; Bupivacaine; Contraindications; Glaucoma; Humans; Male; Middle Aged; Trabeculect

2009