Page last updated: 2024-10-24

bupivacaine and Femur Neck Fractures

bupivacaine has been researched along with Femur Neck Fractures in 30 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Research Excerpts

ExcerptRelevanceReference
"To assess the efficacy of intramuscular ephedrine for prevention of hypotension following subarachnoid block (SB) in the elderly."9.08[Prevention of arterial hypotension during spinal anesthesia using intramuscular ephedrine in older people]. ( Bel, JC; Di Roio, C; Hoen, JP; Lansiaux, S; Magnin, C; Motin, J; Védrinne, JM, 1997)
" alfentanil in terms of facilitating the lateral position for spinal anaesthesia in elderly patients undergoing surgery for femoral neck fractures."5.14Analgesia before a spinal block for femoral neck fracture: fascia iliaca compartment block. ( Do, SH; Han, MK; Hwang, JW; Kim, JH; Kim, YH; Yun, MJ, 2009)
"To assess the efficacy of intramuscular ephedrine for prevention of hypotension following subarachnoid block (SB) in the elderly."5.08[Prevention of arterial hypotension during spinal anesthesia using intramuscular ephedrine in older people]. ( Bel, JC; Di Roio, C; Hoen, JP; Lansiaux, S; Magnin, C; Motin, J; Védrinne, JM, 1997)
" In spinal anaesthesia hypotension of clinical importance was observed coincidentally with the use of methylmethacrylate, while the levels of plasma cortisol remained unchanged."5.06The effect of anaesthesia on changes in blood pressure and plasma cortisol levels induced by cementation with methylmethacrylate. ( Lehtinen, AM; Svartling, N; Tarkkanen, L, 1986)
"Femoral neck fractures are a common and painful injury."2.80Randomised trial of the fascia iliaca block versus the '3-in-1' block for femoral neck fractures in the emergency department. ( Benger, J; Binks, S; Edwards, J; Elder, G; Montgomery, AA; Reavley, P; Smith, JE, 2015)
"Intraoperative hypotension is a common and sometimes deleterious event in elderly patients undergoing spinal anaesthesia for repair of hip fractures."2.70Hypotension in elderly patients undergoing spinal anaesthesia for repair of fractured neck of femur. A comparison of two different spinal solutions. ( Clark, MX; Martyr, JW, 2001)
" The frequency of analgesic use and the occurrence of adverse side effects during the first 48 hours after surgery were compared between the two groups."1.39[Safety and beneficial effects of spinal morphine on the postoperative course of elderly patients undergoing surgical fixation of the femoral neck fracture]. ( Baba, H; Fujiwara, T; Mochida, T; Watanabe, I; Watanabe, T, 2013)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19904 (13.33)18.7374
1990's8 (26.67)18.2507
2000's9 (30.00)29.6817
2010's8 (26.67)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Hitka, T1
O'Sullivan, J1
Szucs, S2
Iohom, G2
Ueshima, H1
Otake, H1
Newman, B1
McCarthy, L1
Thomas, PW1
May, P1
Layzell, M1
Horn, K1
Watanabe, T1
Fujiwara, T1
Mochida, T1
Watanabe, I1
Baba, H1
Reavley, P1
Montgomery, AA1
Smith, JE1
Binks, S1
Edwards, J1
Elder, G1
Benger, J1
Rauf, J1
Shorten, GD1
Odor, PM1
Chis Ster, I1
Wilkinson, I1
Sage, F1
Karacalar, S1
Türe, H1
Sarihasan, B1
Minville, V1
Asehnoune, K1
Delussy, A1
Fourcade, O2
Colombani, A2
Rabinowitz, A1
Samii, K1
Yun, MJ1
Kim, YH1
Han, MK1
Kim, JH1
Hwang, JW1
Do, SH1
Elzinga, L1
Marcus, M1
Peek, D1
Borg, P1
Jansen, J1
Koster, J1
Enk, D1
Frenkel, O1
Mansour, K1
Fischer, JW1
Stuart-Smith, K1
Khatouf, M1
Loughnane, F1
Boini, S1
Heck, M1
Meuret, P1
Macalou, D1
Mertes, PM1
Bouaziz, H1
Kelly, JD1
McCoy, D1
Rosenbaum, SH1
Brull, SJ1
Fuzier, R1
Murat, O1
Gilbert, ML1
Maguès, JP1
Haddad, FS1
Williams, RL1
Ngan-Kee, WD1
Lee, BB1
Lim, W1
Kennedy, N1
Spansberg, NL1
Anker-Møller, E1
Dahl, JB1
Schultz, P1
Christensen, EF1
Mackenzie, J1
Pullinger, R1
Di Roio, C1
Védrinne, JM1
Hoen, JP1
Magnin, C1
Lansiaux, S1
Bel, JC1
Motin, J1
Kajikawa, S1
Suzuki, M1
Yokoi, M1
Martyr, JW1
Clark, MX1
Brands, E1
Callanan, VI1
Adams, HA1
Wolf, C1
Michaelis, G1
Hempelmann, G1
Davies, AJ1
Finlayson, BJ1
Underhill, TJ1
Svartling, N1
Lehtinen, AM1
Tarkkanen, L1
Mericq, O1
Eychenne, B1
Boe, M1
Lareng, L1

Clinical Trials (10)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Determination of the Initial Minimum Effective Dose of 0.5% Bupivacaine With 20mcg of Fentanyl Via a Spinal Catheter for Operative Fixation of Fractured Neck of Femur.[NCT01922622]33 participants (Actual)Observational2013-07-31Completed
Analgesia For Positioning Patient With Femur Fracture For Spinal Anaesthesia : Ultrasound-Guided Fascia Iliaca Compartment Block Versus Intravenous Fentanyl[NCT02983344]24 participants (Actual)Interventional2015-10-31Completed
Comparison of Pericapsular Nerve Group Block (PENG) Versus Fascia Iliaca Compartment Block (FICB) for Hip Fracture Analgesia in Emergency Department Patients[NCT05505604]50 participants (Anticipated)Interventional2022-09-30Recruiting
Determination of the Minimum Local Anaesthetic Needed for Operative Fixation of Fractured Neck of Femur With Continuous Spinal Anaesthesia[NCT01680120]Phase 415 participants (Anticipated)Interventional2012-09-30Not yet recruiting
Pericapsular Nerve Group Block Versus Fascia Iliaca Block for Pre- and Post-Operative Analgesia in Elderly Patients With Hip Fracture[NCT04564326]51 participants (Anticipated)Interventional2021-01-01Not yet recruiting
Fascia Iliaca Compartment Block Versus Fentanyl for Positioning Patients With Hip Fractures for Central Nervous Blockade: a Randomized Trial.[NCT02037633]41 participants (Actual)Interventional2012-07-31Completed
Ultrasound Guided Transversus Abdominis Plane Block Versus Erector Spina Plane Block in Pediatric Lower Abdominal Surgery[NCT04095325]100 participants (Anticipated)Interventional2019-10-01Not yet recruiting
Effect of Ultrasonography Guided Transversus Abdominis Plane Block to Intraoperative Anesthesia in Children: Randomized Controlled Study[NCT02990975]60 participants (Anticipated)Interventional2016-12-31Active, not recruiting
Ultrasonography Guided Ilioinguinal /Iliohypogastric Block Versus Transversus Abdominis Plane Block in Intraoperative Anesthesia in Children - Randomized Controlled Study[NCT02991053]100 participants (Anticipated)Interventional2016-12-31Active, not recruiting
Trial of Ultrasound Guided Femoral Nerve Block on Isolated Femur Fracture Using Echo Friendly Needles[NCT02046317]Phase 412 participants (Actual)Interventional2011-05-31Terminated (stopped due to No further enrolled patients, Primary researcher left the institution)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Patient Pain Level

Pain level will be measured on a numeric visual analogue scale of 0-10 with 0 being no pain and 10 being the worst pain ever. (NCT02046317)
Timeframe: 60 minutes after initial femoral block

Interventionunits on a scale (Mean)
Echogenic Needle1.25
Standard of Care Needle3.75

Patient Pain Level

Pain level will be measured on a numeric visual analogue scale of 0-10 with 0 being no pain and 10 being the worst pain ever. (NCT02046317)
Timeframe: baseline

Interventionunits on a scale (Mean)
Echogenic Needle7.50
Standard of Care Needle8.00

Trials

11 trials available for bupivacaine and Femur Neck Fractures

ArticleYear
A comparison of pre-operative nerve stimulator-guided femoral nerve block and fascia iliaca compartment block in patients with a femoral neck fracture.
    Anaesthesia, 2013, Volume: 68, Issue:9

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Electric Stimulation;

2013
Randomised trial of the fascia iliaca block versus the '3-in-1' block for femoral neck fractures in the emergency department.
    Emergency medicine journal : EMJ, 2015, Volume: 32, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Emergency Service, Hospital; Female

2015
Determination of the minimum initial intrathecal dose of isobaric 0.5% bupivacaine for the surgical repair of a proximal femoral fracture: A prospective, observational trial.
    European journal of anaesthesiology, 2015, Volume: 32, Issue:11

    Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Dose-Response Relation

2015
Analgesia before a spinal block for femoral neck fracture: fascia iliaca compartment block.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Alfentanil; Analgesia; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics,

2009
Analgesia before a spinal block for femoral neck fracture: fascia iliaca compartment block.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Alfentanil; Analgesia; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics,

2009
Analgesia before a spinal block for femoral neck fracture: fascia iliaca compartment block.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Alfentanil; Analgesia; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics,

2009
Analgesia before a spinal block for femoral neck fracture: fascia iliaca compartment block.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Alfentanil; Analgesia; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics,

2009
Analgesia before a spinal block for femoral neck fracture: fascia iliaca compartment block.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Alfentanil; Analgesia; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics,

2009
Analgesia before a spinal block for femoral neck fracture: fascia iliaca compartment block.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Alfentanil; Analgesia; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics,

2009
Analgesia before a spinal block for femoral neck fracture: fascia iliaca compartment block.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Alfentanil; Analgesia; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics,

2009
Analgesia before a spinal block for femoral neck fracture: fascia iliaca compartment block.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Alfentanil; Analgesia; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics,

2009
Analgesia before a spinal block for femoral neck fracture: fascia iliaca compartment block.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:10

    Topics: Aged; Aged, 80 and over; Alfentanil; Analgesia; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics,

2009
Haemodynamic changes induced by hyperbaric bupivacaine during lateral decubitus or supine spinal anaesthesia.
    European journal of anaesthesiology, 2005, Volume: 22, Issue:9

    Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Blood Pressure; Bupivacaine; Ephedr

2005
Femoral nerve block in extracapsular femoral neck fractures.
    The Journal of bone and joint surgery. British volume, 1995, Volume: 77, Issue:6

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Bupivacaine; Diclofenac; Female; Femoral Neck Fractures

1995
The value of continuous blockade of the lumbar plexus as an adjunct to acetylsalicyclic acid for pain relief after surgery for femoral neck fractures.
    European journal of anaesthesiology, 1996, Volume: 13, Issue:4

    Topics: Administration, Rectal; Aged; Aged, 80 and over; Analgesia; Analgesics, Opioid; Anesthesia, Spinal;

1996
[Prevention of arterial hypotension during spinal anesthesia using intramuscular ephedrine in older people].
    Annales francaises d'anesthesie et de reanimation, 1997, Volume: 16, Issue:5

    Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Double-Blind Method; E

1997
Hypotension in elderly patients undergoing spinal anaesthesia for repair of fractured neck of femur. A comparison of two different spinal solutions.
    Anaesthesia and intensive care, 2001, Volume: 29, Issue:5

    Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Bupivacai

2001
[Postoperative course and endocrine stress reaction of geriatric patients with para-articular hip fractures. Prospective randomized study comparing spinal anesthesia and halothane intubation narcosis].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1990, Volume: 25, Issue:4

    Topics: Adrenocorticotropic Hormone; Aged; Aged, 80 and over; Anesthesia, Endotracheal; Anesthesia, Spinal;

1990
The effect of anaesthesia on changes in blood pressure and plasma cortisol levels induced by cementation with methylmethacrylate.
    Acta anaesthesiologica Scandinavica, 1986, Volume: 30, Issue:3

    Topics: Aged; Anesthesia, Endotracheal; Anesthesia, Spinal; Bupivacaine; Female; Femoral Neck Fractures; Hip

1986

Other Studies

19 other studies available for bupivacaine and Femur Neck Fractures

ArticleYear
Determination of the initial minimum effective dose of 0.5% bupivacaine with 20 μg of fentanyl for an operative fixation of fractured neck of femur: a prospective, observational trial.
    Minerva anestesiologica, 2021, Volume: 87, Issue:7

    Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Double-Blind Method; Femoral Neck Fractur

2021
Supra-inguinal fascia iliaca block under ultrasound guidance for perioperative analgesia during bipolar hip arthroplasty in a patient with severe cardiovascular compromise: A case report.
    Medicine, 2018, Volume: 97, Issue:40

    Topics: Aged; Analgesia; Anesthetics, Local; Arthroplasty, Replacement, Hip; Bupivacaine; Cardiovascular Dis

2018
[Safety and beneficial effects of spinal morphine on the postoperative course of elderly patients undergoing surgical fixation of the femoral neck fracture].
    Masui. The Japanese journal of anesthesiology, 2013, Volume: 62, Issue:6

    Topics: Aged, 80 and over; Analgesics; Anesthesia, Spinal; Bupivacaine; Female; Femoral Neck Fractures; Huma

2013
Effect of admission fascia iliaca compartment blocks on post-operative abbreviated mental test scores in elderly fractured neck of femur patients: a retrospective cohort study.
    BMC anesthesiology, 2017, Jan-05, Volume: 17, Issue:1

    Topics: Aged, 80 and over; Anesthetics, Local; Bupivacaine; Cognitive Dysfunction; Female; Femoral Neck Frac

2017
Unilateral spinal anesthesia in two centenarian patients.
    Journal of clinical anesthesia, 2008, Volume: 20, Issue:6

    Topics: Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Female; Femoral Neck Fractur

2008
Hypotension during surgery for femoral neck fracture in elderly patients: effect of anaesthetic techniques. A retrospective study.
    Minerva anestesiologica, 2008, Volume: 74, Issue:12

    Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; F

2008
Hemodynamic stability ensured by a low dose, low volume, unilateral hypobaric spinal block: modification of a technique.
    Acta anaesthesiologica Belgica, 2009, Volume: 60, Issue:4

    Topics: Aged, 80 and over; Air Pressure; Anesthesia, Spinal; Anesthetics, Local; Aortic Valve Stenosis; Arth

2009
Ultrasound-guided femoral nerve block for pain control in an infant with a femur fracture due to nonaccidental trauma.
    Pediatric emergency care, 2012, Volume: 28, Issue:2

    Topics: Acute Pain; Analgesia; Anesthetics, Local; Bupivacaine; Child Abuse; Combined Modality Therapy; Fema

2012
Hemiarthroplasty performed under transversus abdominis plane block in a patient with severe cardiorespiratory disease.
    Anaesthesia, 2013, Volume: 68, Issue:4

    Topics: Abdomen; Aged; Anesthetics, Combined; Anesthetics, Local; Atrial Fibrillation; Bupivacaine; Fatal Ou

2013
Hemiarthroplasty performed under transversus abdominis plane block in a patient with severe cardiorespiratory disease.
    Anaesthesia, 2013, Volume: 68, Issue:4

    Topics: Abdomen; Aged; Anesthetics, Combined; Anesthetics, Local; Atrial Fibrillation; Bupivacaine; Fatal Ou

2013
Hemiarthroplasty performed under transversus abdominis plane block in a patient with severe cardiorespiratory disease.
    Anaesthesia, 2013, Volume: 68, Issue:4

    Topics: Abdomen; Aged; Anesthetics, Combined; Anesthetics, Local; Atrial Fibrillation; Bupivacaine; Fatal Ou

2013
Hemiarthroplasty performed under transversus abdominis plane block in a patient with severe cardiorespiratory disease.
    Anaesthesia, 2013, Volume: 68, Issue:4

    Topics: Abdomen; Aged; Anesthetics, Combined; Anesthetics, Local; Atrial Fibrillation; Bupivacaine; Fatal Ou

2013
Hemiarthroplasty performed under transversus abdominis plane block in a patient with severe cardiorespiratory disease.
    Anaesthesia, 2013, Volume: 68, Issue:4

    Topics: Abdomen; Aged; Anesthetics, Combined; Anesthetics, Local; Atrial Fibrillation; Bupivacaine; Fatal Ou

2013
Hemiarthroplasty performed under transversus abdominis plane block in a patient with severe cardiorespiratory disease.
    Anaesthesia, 2013, Volume: 68, Issue:4

    Topics: Abdomen; Aged; Anesthetics, Combined; Anesthetics, Local; Atrial Fibrillation; Bupivacaine; Fatal Ou

2013
Hemiarthroplasty performed under transversus abdominis plane block in a patient with severe cardiorespiratory disease.
    Anaesthesia, 2013, Volume: 68, Issue:4

    Topics: Abdomen; Aged; Anesthetics, Combined; Anesthetics, Local; Atrial Fibrillation; Bupivacaine; Fatal Ou

2013
Hemiarthroplasty performed under transversus abdominis plane block in a patient with severe cardiorespiratory disease.
    Anaesthesia, 2013, Volume: 68, Issue:4

    Topics: Abdomen; Aged; Anesthetics, Combined; Anesthetics, Local; Atrial Fibrillation; Bupivacaine; Fatal Ou

2013
Hemiarthroplasty performed under transversus abdominis plane block in a patient with severe cardiorespiratory disease.
    Anaesthesia, 2013, Volume: 68, Issue:4

    Topics: Abdomen; Aged; Anesthetics, Combined; Anesthetics, Local; Atrial Fibrillation; Bupivacaine; Fatal Ou

2013
[Unilateral spinal anaesthesia in elderly patient for hip trauma: a pilot study].
    Annales francaises d'anesthesie et de reanimation, 2005, Volume: 24, Issue:3

    Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Blood Pressure; Bupivacaine; Ephedr

2005
[Continuous spinal anesthesia for femoral fracture in two patients with severe aortic stenosis].
    Annales francaises d'anesthesie et de reanimation, 2006, Volume: 25, Issue:5

    Topics: Aged, 80 and over; Anesthesia, Spinal; Aortic Valve Stenosis; Arthroplasty, Replacement, Hip; Bone N

2006
Cardiovascular collapse after combined spinal anaesthesia and interscalene brachial plexus block.
    Anaesthesia and intensive care, 1995, Volume: 23, Issue:2

    Topics: Aged; Anesthesia, Spinal; Brachial Plexus; Bupivacaine; Femoral Neck Fractures; Fracture Fixation, I

1995
Hemi-arthroplasty of the hip under triple nerve block.
    Anaesthesia and intensive care, 1994, Volume: 22, Issue:6

    Topics: Aged; Aged, 80 and over; Bupivacaine; Femoral Neck Fractures; Femoral Nerve; Hip Joint; Hip Prosthes

1994
The groin cannula: effective pain relief for fractured neck of femur.
    Journal of accident & emergency medicine, 1997, Volume: 14, Issue:4

    Topics: Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Clinical Protocols; Emergency Service, Hos

1997
[Preoperative complications and intraoperative hemodynamic changes in very old patients with femoral neck fractures].
    Masui. The Japanese journal of anesthesiology, 2000, Volume: 49, Issue:9

    Topics: Aged; Aged, 80 and over; Anemia; Anesthesia, General; Anesthesia, Spinal; Bupivacaine; Femoral Neck

2000
Continuous lumbar plexus block--analgesia for femoral neck fractures.
    Anaesthesia and intensive care, 1978, Volume: 6, Issue:3

    Topics: Aged; Analgesia; Blood Pressure; Bupivacaine; Female; Femoral Neck Fractures; Humans; Lumbosacral Pl

1978
Dosage volume or concentration?
    Anaesthesia, 1990, Volume: 45, Issue:5

    Topics: Analgesia; Anesthesia, Spinal; Bupivacaine; Femoral Neck Fractures; Humans; Prospective Studies

1990
Femoral nerve block for analgesia in fractures of the femoral neck.
    Archives of emergency medicine, 1988, Volume: 5, Issue:3

    Topics: Adult; Aged; Bupivacaine; Evaluation Studies as Topic; Female; Femoral Neck Fractures; Femoral Nerve

1988
[Paramedian lumbar puncture for spinal anesthesia in the elderly].
    Cahiers d'anesthesiologie, 1985, Volume: 33, Issue:8

    Topics: Aged; Anesthesia, Spinal; Bupivacaine; Femoral Neck Fractures; Humans; Spinal Puncture; Tetracaine

1985