bupivacaine has been researched along with Femoral Fractures in 29 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Femoral Fractures: Fractures of the femur.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 μg of dexmedetomidine to bupivacaine for subarachnoid block in the management of femoral fractures using ORIF provided better anesthetic profile, particularly prolonged duration of postoperative analgesia without significant side effects." | 9.34 | Postoperative analgesic effect of intrathecal dexmedetomidine on bupivacaine subarachnoid block for open reduction and internal fixation of femoral fractures. ( Edomwonyi, NP; Idehen, HO; Nwachukwu, C; Umeh, B, 2020) |
| "5 μg of dexmedetomidine to bupivacaine for subarachnoid block in the management of femoral fractures using ORIF provided better anesthetic profile, particularly prolonged duration of postoperative analgesia without significant side effects." | 5.34 | Postoperative analgesic effect of intrathecal dexmedetomidine on bupivacaine subarachnoid block for open reduction and internal fixation of femoral fractures. ( Edomwonyi, NP; Idehen, HO; Nwachukwu, C; Umeh, B, 2020) |
| "5% bupivacaine) along with standard pain management or (b) standard pain management alone (typically intravenous narcotics)." | 5.12 | Femoral nerve block for diaphyseal and distal femoral fractures in the emergency department. ( Anders, MJ; Bone, LB; Jensen, EJ; Manka, MA; Mutty, CE, 2007) |
| "Bupivacaine metabolites were not detected." | 2.71 | Steady state bupivacaine plasma concentrations and safety of a femoral "3-in-1" nerve block with bupivacaine in patients over 80 years of age. ( Gielen, MJ; Lagerwert, AJ; Snoeck, MM; Vree, TB, 2003) |
| " No severe adverse effects were noted." | 2.70 | Continuous fascia iliaca compartment block in children: a prospective evaluation of plasma bupivacaine concentrations, pain scores, and side effects. ( Bruguerolle, B; Camboulives, J; Paut, O; Rémond, C; Sallabery, M; Schreiber-Deturmeny, E, 2001) |
| "Effective approaches to reducing postoperative pain in orthopedic trauma surgery patients include the use of minimally invasive procedures and multimodal analgesia." | 2.50 | Local infiltration of liposome bupivacaine in orthopedic trauma patients: case-based reviews. ( Hutchinson, HL, 2014) |
| "Kyphoscoliosis is a progressive disease that worsens with age." | 1.38 | [Combined spinal epidural anesthesia in a patient with advanced kyphoscoliosis]. ( Akyol, O; Ozyuvaci, EN; Solak, S; Solak, Z; Toprak, N; Tuluk, G, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (17.24) | 18.7374 |
| 1990's | 2 (6.90) | 18.2507 |
| 2000's | 12 (41.38) | 29.6817 |
| 2010's | 7 (24.14) | 24.3611 |
| 2020's | 3 (10.34) | 2.80 |
| Authors | Studies |
|---|---|
| Jain, N | 1 |
| Kotulski, C | 1 |
| Al-Hilli, A | 1 |
| Yeung-Lai-Wah, P | 1 |
| Pluta, J | 1 |
| Heegeman, D | 1 |
| Nwachukwu, C | 1 |
| Idehen, HO | 1 |
| Edomwonyi, NP | 1 |
| Umeh, B | 1 |
| Aissa, I | 1 |
| Wartiti, LE | 1 |
| Bouhaba, N | 1 |
| Khallikane, S | 1 |
| Moutaoukil, M | 1 |
| Kartite, N | 1 |
| Elkoundi, A | 1 |
| Benakrout, A | 1 |
| Chlouchi, A | 1 |
| Elbouti, A | 1 |
| Najout, H | 1 |
| Grine, A | 1 |
| Touab, R | 1 |
| Zaizi, A | 1 |
| Youssef, J | 1 |
| Bakkali, H | 1 |
| Balkhi, H | 1 |
| Bensghir, M | 1 |
| Royal, JM | 1 |
| Settle, TL | 1 |
| Bodo, M | 1 |
| Lombardini, E | 1 |
| Kent, ML | 1 |
| Upp, J | 1 |
| Rothwell, SW | 1 |
| Uzawa, K | 1 |
| Hakone, M | 1 |
| Nakazawa, H | 1 |
| Yasuda, H | 1 |
| Moriyama, K | 1 |
| Yorozu, T | 1 |
| Hutchinson, HL | 1 |
| Ueshima, H | 1 |
| Otake, H | 1 |
| Rogers, BA | 1 |
| Rang, S | 1 |
| Mutty, CE | 2 |
| Jensen, EJ | 2 |
| Manka, MA | 2 |
| Anders, MJ | 2 |
| Bone, LB | 2 |
| Nozaka, K | 1 |
| Matsumoto, S | 1 |
| Yamamoto, N | 1 |
| Komatsu, H | 1 |
| Wood, RJ | 1 |
| White, SM | 1 |
| Solak, S | 1 |
| Ozyuvaci, EN | 1 |
| Tuluk, G | 1 |
| Solak, Z | 1 |
| Akyol, O | 1 |
| Toprak, N | 1 |
| Aguiar, J | 1 |
| Mogridge, G | 1 |
| Hall, J | 1 |
| Dobrydnjov, I | 1 |
| Axelsson, K | 1 |
| Samarütel, J | 1 |
| Holmström, B | 1 |
| Henry, BJ | 1 |
| Kenison, M | 1 |
| McVay, C | 1 |
| Rolfe, R | 1 |
| Graham, S | 1 |
| Rasty, J | 1 |
| Slauterbeck, J | 1 |
| Dabezies, EJ | 1 |
| Snoeck, MM | 1 |
| Vree, TB | 1 |
| Gielen, MJ | 1 |
| Lagerwert, AJ | 1 |
| Chu, RS | 1 |
| Browne, GJ | 1 |
| Cheng, NG | 1 |
| Lam, LT | 1 |
| Triner, W | 1 |
| Levine, J | 1 |
| Lai, SY | 1 |
| McErlean, M | 1 |
| Fuzier, R | 1 |
| Murat, O | 1 |
| Gilbert, ML | 1 |
| Maguès, JP | 1 |
| Fourcade, O | 1 |
| Khoo, ST | 1 |
| Brown, TC | 1 |
| Tobias, JD | 1 |
| Johnson, CM | 1 |
| Van Leeuwen, FL | 1 |
| Bronselaer, K | 1 |
| Gilles, M | 1 |
| Sabbe, MB | 1 |
| Delooz, HH | 1 |
| Paut, O | 1 |
| Sallabery, M | 1 |
| Schreiber-Deturmeny, E | 1 |
| Rémond, C | 1 |
| Bruguerolle, B | 1 |
| Camboulives, J | 1 |
| Ronchi, L | 1 |
| Rosenbaum, D | 1 |
| Athouel, A | 1 |
| Lemaitre, JL | 1 |
| Bermon, F | 1 |
| de Villepoix, C | 1 |
| Le Normand, Y | 1 |
| Denton, JS | 1 |
| Manning, MP | 1 |
| Petitcolin, PB | 1 |
| Mathé, D | 1 |
| Grouille, D | 1 |
| Boulogne, P | 1 |
| Terrier, G | 1 |
| Lansade, A | 1 |
| Dahl, JB | 1 |
| Daugaard, JJ | 1 |
| Dahl, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Does the Use of Liposomal Bupivacaine Decrease Narcotic Requirements in Geriatric Hip Fractures? A Randomized, Double Blinded Control Trial[NCT03289858] | Phase 4 | 55 participants (Actual) | Interventional | 2017-09-01 | Completed | ||
| A Prospective, Randomized Trial Evaluating Regional Anesthesia, Long-Acting Local Anesthesia, and Traditional Care for Pain Control of Operatively Treated Ankle Fractures[NCT03696199] | Phase 4 | 70 participants (Anticipated) | Interventional | 2020-09-01 | Recruiting | ||
| The Efficacy of Ultrasound-Guided Quadratus Lumborum Block for Pain Management Following Lumbar Spinal Surgery[NCT04981301] | 60 participants (Actual) | Interventional | 2021-08-02 | Completed | |||
| Comparison of the Effectiveness of Ultrasound-Guided Quadratus Lumborum 2 Block and Classic Thoracolumbar Interfacial Plane Block in the Management of Postoperative Analgesia After Lumbar Spinal Surgery[NCT05421585] | 57 participants (Actual) | Interventional | 2022-08-15 | Completed | |||
| A Randomized, Double Blind, Placebo Controlled Evaluation Trial of the Benefit in Quadratus Lumborum Block as a Postoperative Analgesic Technique for a Lumbar Spine Decompression and Fusion Surgery[NCT04447950] | 100 participants (Anticipated) | Interventional | 2020-06-30 | Not yet recruiting | |||
| Trial of Ultrasound Guided Femoral Nerve Block on Isolated Femur Fracture Using Echo Friendly Needles[NCT02046317] | Phase 4 | 12 participants (Actual) | Interventional | 2011-05-31 | Terminated (stopped due to No further enrolled patients, Primary researcher left the institution) | ||
| Preventive Norepinephrine Infusion During Surgery for Upper Femoral Fracture and Post-operative Acute Renal Failure[NCT05566132] | 676 participants (Actual) | Observational | 2022-08-09 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Morphine meq given (NCT03289858)
Timeframe: 72 hours
| Intervention | Morphine mEq (Mean) |
|---|---|
| Exparel (Liposomal Bupivacaine) | 52.5 |
| Saline Control | 65.39 |
Pain level will be measured on a numeric visual analogue scale of 0-10 with 0 being no pain and 10 being the worst pain ever. (NCT02046317)
Timeframe: 60 minutes after initial femoral block
| Intervention | units on a scale (Mean) |
|---|---|
| Echogenic Needle | 1.25 |
| Standard of Care Needle | 3.75 |
Pain level will be measured on a numeric visual analogue scale of 0-10 with 0 being no pain and 10 being the worst pain ever. (NCT02046317)
Timeframe: baseline
| Intervention | units on a scale (Mean) |
|---|---|
| Echogenic Needle | 7.50 |
| Standard of Care Needle | 8.00 |
1 review available for bupivacaine and Femoral Fractures
| Article | Year |
|---|---|
Local infiltration of liposome bupivacaine in orthopedic trauma patients: case-based reviews.
Topics: Adult; Anesthetics, Local; Bupivacaine; Clavicle; Female; Femoral Fractures; Fracture Fixation, Inte | 2014 |
Local infiltration of liposome bupivacaine in orthopedic trauma patients: case-based reviews.
Topics: Adult; Anesthetics, Local; Bupivacaine; Clavicle; Female; Femoral Fractures; Fracture Fixation, Inte | 2014 |
Local infiltration of liposome bupivacaine in orthopedic trauma patients: case-based reviews.
Topics: Adult; Anesthetics, Local; Bupivacaine; Clavicle; Female; Femoral Fractures; Fracture Fixation, Inte | 2014 |
Local infiltration of liposome bupivacaine in orthopedic trauma patients: case-based reviews.
Topics: Adult; Anesthetics, Local; Bupivacaine; Clavicle; Female; Femoral Fractures; Fracture Fixation, Inte | 2014 |
7 trials available for bupivacaine and Femoral Fractures
| Article | Year |
|---|---|
Postoperative analgesic effect of intrathecal dexmedetomidine on bupivacaine subarachnoid block for open reduction and internal fixation of femoral fractures.
Topics: Adult; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anesthesia, Spinal; Anesthetics, Local; Bupi | 2020 |
Assessment of postoperative analgesia after application of ultrasound-guided regional anesthesia for surgery in a swine femoral fracture model.
Topics: Analgesics; Anesthetics, Local; Animals; Bupivacaine; Buprenorphine; Catheters; Female; Femoral Frac | 2013 |
Femoral nerve block for diaphyseal and distal femoral fractures in the emergency department. Surgical technique.
Topics: Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Emergency Service, Hospital; Femoral Fractures; | 2008 |
Postoperative pain relief following intrathecal bupivacaine combined with intrathecal or oral clonidine.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Adult; Analgesics; Anesthesia, Spinal; Anesthetics, | 2002 |
Steady state bupivacaine plasma concentrations and safety of a femoral "3-in-1" nerve block with bupivacaine in patients over 80 years of age.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Anesthetics, Local; Bupivacaine; Female; Femoral Frac | 2003 |
Femoral nerve block for diaphyseal and distal femoral fractures in the emergency department.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, Local; Bupivacaine; Fema | 2007 |
Continuous fascia iliaca compartment block in children: a prospective evaluation of plasma bupivacaine concentrations, pain scores, and side effects.
Topics: Adolescent; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Femoral Fractures; Femoral Ner | 2001 |
21 other studies available for bupivacaine and Femoral Fractures
| Article | Year |
|---|---|
Fascia Iliaca Block in Hip and Femur Fractures to Reduce Opioid Use.
Topics: Adult; Analgesics, Opioid; Bupivacaine; Epinephrine; Fascia; Femoral Fractures; Femur; Humans; Morph | 2022 |
[Combined lumbar plexus-sciatic nerve block in the emergency surgery for pertrochanteric fracture: an alternative technique in patients at high risk of anaesthetic complications].
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Cross-Sectional Studies; Female; Femoral F | 2020 |
[Spinal anesthesia using a low dose of isobaric bupivacaine in a patient with pulmonary artery hypertension and mixed obstructive and restrictive lung disease undergoing repeated femoral fracture surgery].
Topics: Aged; Anesthesia, Spinal; Bupivacaine; Female; Femoral Fractures; Forced Expiratory Volume; Humans; | 2014 |
RETRACTED: Clinical experience of anterior quadratus lumborum block after lumber surgery.
Topics: Abdominal Muscles; Analgesia; Anesthesia, General; Anesthetics, Local; Bupivacaine; Femoral Fracture | 2017 |
RETRACTED: Clinical experience of anterior quadratus lumborum block after lumber surgery.
Topics: Abdominal Muscles; Analgesia; Anesthesia, General; Anesthetics, Local; Bupivacaine; Femoral Fracture | 2017 |
RETRACTED: Clinical experience of anterior quadratus lumborum block after lumber surgery.
Topics: Abdominal Muscles; Analgesia; Anesthesia, General; Anesthetics, Local; Bupivacaine; Femoral Fracture | 2017 |
RETRACTED: Clinical experience of anterior quadratus lumborum block after lumber surgery.
Topics: Abdominal Muscles; Analgesia; Anesthesia, General; Anesthetics, Local; Bupivacaine; Femoral Fracture | 2017 |
RETRACTED: Clinical experience of anterior quadratus lumborum block after lumber surgery.
Topics: Abdominal Muscles; Analgesia; Anesthesia, General; Anesthetics, Local; Bupivacaine; Femoral Fracture | 2017 |
RETRACTED: Clinical experience of anterior quadratus lumborum block after lumber surgery.
Topics: Abdominal Muscles; Analgesia; Anesthesia, General; Anesthetics, Local; Bupivacaine; Femoral Fracture | 2017 |
RETRACTED: Clinical experience of anterior quadratus lumborum block after lumber surgery.
Topics: Abdominal Muscles; Analgesia; Anesthesia, General; Anesthetics, Local; Bupivacaine; Femoral Fracture | 2017 |
RETRACTED: Clinical experience of anterior quadratus lumborum block after lumber surgery.
Topics: Abdominal Muscles; Analgesia; Anesthesia, General; Anesthetics, Local; Bupivacaine; Femoral Fracture | 2017 |
RETRACTED: Clinical experience of anterior quadratus lumborum block after lumber surgery.
Topics: Abdominal Muscles; Analgesia; Anesthesia, General; Anesthetics, Local; Bupivacaine; Femoral Fracture | 2017 |
Femoral nerve block for diaphyseal and distal femoral fractures in the emergency department.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, Local; Bupivacaine; Fema | 2008 |
[Anesthetic management of a patient before the onset and during the healing stages of Takotsubo cardiomyopathy].
Topics: Aged, 80 and over; Anesthesia, Spinal; Bupivacaine; Female; Femoral Fractures; Humans; Hypotension; | 2009 |
Anaesthesia for 1131 patients undergoing proximal femoral fracture repair: a retrospective, observational study of effects on blood pressure, fluid administration and perioperative anaemia.
Topics: Aged; Aged, 80 and over; Anemia; Anesthesia; Blood Pressure; Bupivacaine; Female; Femoral Fractures; | 2011 |
[Combined spinal epidural anesthesia in a patient with advanced kyphoscoliosis].
Topics: Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Female; Femoral Fractures | 2012 |
Femoral fracture repair and sciatic and femoral nerve blocks in a guinea pig.
Topics: Anesthesia; Anesthetics, Combined; Animals; Bone Wires; Bupivacaine; Buprenorphine; Femoral Fracture | 2014 |
The effect of local hematoma blocks on early fracture healing.
Topics: Analysis of Variance; Animals; Bupivacaine; Disease Models, Animal; Femoral Fractures; Fracture Fixa | 2002 |
Femoral nerve block for femoral shaft fractures in a paediatric Emergency Department: can it be done better?
Topics: Anesthesiology; Australia; Bupivacaine; Child; Child, Preschool; Emergency Service, Hospital; Female | 2003 |
Femoral nerve block for femur fractures.
Topics: Analgesia; Bupivacaine; Femoral Fractures; Femoral Nerve; Humans; Nerve Block; Pain; Pilot Projects | 2005 |
[Continuous spinal anesthesia for femoral fracture in two patients with severe aortic stenosis].
Topics: Aged, 80 and over; Anesthesia, Spinal; Aortic Valve Stenosis; Arthroplasty, Replacement, Hip; Bone N | 2006 |
Femoral nerve block--the anatomical basis for a single injection technique.
Topics: Bupivacaine; Fascia; Femoral Artery; Femoral Fractures; Femoral Nerve; Femoral Vein; Humans; Injecti | 1983 |
Continuous femoral nerve block to provide analgesia following femur fracture in a paediatric ICU population.
Topics: Analgesia; Bupivacaine; Catheterization, Peripheral; Child; Critical Care; Femoral Fractures; Femora | 1994 |
Continuous femoral nerve blockade for analgesia in children with femoral fractures.
Topics: Acetaminophen; Adolescent; Analgesia; Analgesia, Epidural; Bupivacaine; Child; Child, Preschool; Cod | 1994 |
The 'three in one' block as locoregional analgesia in an emergency department.
Topics: Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Drug Combinations; Emergency Treatment; | 2000 |
Femoral nerve blockade in children using bupivacaine.
Topics: Bupivacaine; Child; Child, Preschool; Femoral Fractures; Femoral Nerve; Humans; Nerve Block | 1989 |
Femoral nerve block for femoral shaft fractures in children: brief report.
Topics: Bupivacaine; Child; Femoral Fractures; Femoral Nerve; Humans; Nerve Block | 1988 |
[The lidocaine-bupivacaine combination for crural nerve block].
Topics: Adult; Bupivacaine; Child; Drug Combinations; Female; Femoral Fractures; Femoral Nerve; Humans; Lido | 1987 |
[Use of a femoral catheter in femoral fractures in children].
Topics: Bupivacaine; Catheters, Indwelling; Child; Female; Femoral Fractures; Femoral Nerve; Humans; Morphin | 1987 |