Page last updated: 2024-10-24

bupivacaine and Fatigue

bupivacaine has been researched along with Fatigue in 5 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.

Research Excerpts

Excerpt	Relevance	Reference
"Late postoperative pain, fatigue and conservative attitudes and routines in the postoperative care, were the most important reasons limiting mobilization and activity."	2.67	The effect of balanced analgesia on early convalescence after major orthopaedic surgery. ( Dahl, JB; Gebuhr, P; Hansen, BL; Hjortsø, NC; Kehlet, H; Møiniche, S; Rosenberg, J, 1994)
"Postoperative pain was assessed by linear analogue and ventilatory capacity."	2.67	Interpleural catheter for analgesia after cholecystectomy: the surgical perspective. ( Baker, P; Schroeder, D, 1990)

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Møiniche, S	2
Bülow, S	1
Hesselfeldt, P	1
Hestbaek, A	1
Kehlet, H	4
Bardram, L	1
Funch-Jensen, P	1
Jensen, P	1
Crawford, ME	1
Hjortsø, NC	1
Hansen, BL	1
Dahl, JB	1
Rosenberg, J	1
Gebuhr, P	1
Schulze, S	1
Sommer, P	1
Bigler, D	1
Honnens, M	1
Shenkin, A	1
Cruickshank, AM	1
Bukhave, K	1
Schroeder, D	1
Baker, P	1

Clinical Trials (7)

Trial Overview

Trial	Enrollment	Study Type	Start Date	Status
Randomized Clinical Trial Comparing the Use of Perioperative Epidural Analgesia to Conventional Intravenous Narcotics and NSAIDS for Patients Undergoing Laparoscopic Colorectal Resection[NCT02086123]	87 participants (Actual)	Interventional	2012-05-31	Completed
Randomized Controlled Trial Assessing the Value of Prehabilitation in Patients Undergoing Colorectal Surgery According to the ERAS Protocol for the Improvement of Postoperative Outcomes[NCT02746731]	112 participants (Actual)	Interventional	2016-06-30	Completed
Clinical and Economical Evaluation of Colorectal Surgery in Ambulatory Care[NCT03760939]	140 participants (Anticipated)	Interventional	2019-01-03	Recruiting
ERAS Lazio Network Clinical Registry[NCT03353311]	1,000 participants (Actual)	Observational [Patient Registry]	2014-09-01	Completed
Fast-track Surgery After Gynaecological Oncological Surgery[NCT02687412]	107 participants (Actual)	Interventional	2016-11-21	Completed
Internet-based Perioperative Exercise Program in Patients With Barrett's Carcinoma Scheduled for Esophagectomy (iPEP Study) A Prospective Randomized-controlled Pilot Trial[NCT02478996]	80 participants (Anticipated)	Interventional	2015-08-31	Recruiting
Impact on the Hospital Stay, of an Early Oral Nutrition Protocol Applied to Gastric Cancer Patients After Total Gastrectomy: A Prospective Randomized Control Trial (DOPGT_2015)[NCT03257280]	84 participants (Anticipated)	Interventional	2017-10-20	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Cost of Surgical Therapy

Cost of surgical therapy (RMB) (NCT02687412)
Timeframe: 12 month

Intervention	RMB (Mean)
Fast-track Surgery	9703.22
Traditional Surgery	9538.47

CRP

C-Reactive protein mg/L (NCT02687412)
Timeframe: up to 12 months

Intervention	mg/L (Mean)
Fast-track Surgery	42.125
Traditional Surgery	62.499

Length of Hospitalization Post-operation

days from operation date to discharge date (NCT02687412)
Timeframe: up to 12 months

Intervention	days (Mean)
Fast-track Surgery	8.92
Traditional Surgery	9.67

Number of Participants With Complications

Count of patients with complications in both groups are assessed during the first 21 days postoperatively. Including infection(wound infection, lung infection, intraperitoneal infection, operation space infection), postoperative nausea and vomiting (PONV) , ileus, postoperative hemorrhage, postoperative thrombosis. (NCT02687412)
Timeframe: up to 12 months

Intervention	Participants (Count of Participants)
Fast-track Surgery	3
Traditional Surgery	13

Number of Participants With Ileus

is a disruption of the normal propulsive ability of the gastrointestinal tract (NCT02687412)
Timeframe: up to 12 months

Intervention	Participants (Count of Participants)
Fast-track Surgery	1
Traditional Surgery	1

Number of Participants With Infection,

infection(wound infection, lung infection, intraperitoneal infection, operation space infection) (NCT02687412)
Timeframe: up to 12 months

Intervention	Participants (Count of Participants)
Fast-track Surgery	2
Traditional Surgery	12

Number of Participants With Postoperative Haemorrhage

Evidence of blood loss from drains or based on ultrasonography (NCT02687412)
Timeframe: up to 12 months

Intervention	Participants (Count of Participants)
Fast-track Surgery	0
Traditional Surgery	0

Number of Participants With Postoperative Nausea and Vomiting (PONV)

it was recognized that nausea and vomiting are common side effects of surgical recovery (NCT02687412)
Timeframe: up to 12 months

Intervention	Participants (Count of Participants)
Fast-track Surgery	0
Traditional Surgery	0

Number of Participants With Postoperative Thrombosis

Evidence of blood thrombosis of participants after surgery (NCT02687412)
Timeframe: up to 12 months

Intervention	Participants (Count of Participants)
Fast-track Surgery	0
Traditional Surgery	0

PCT Calcitonin Postoperative

value of calcitonin postoperative (NCT02687412)
Timeframe: 12 month

Intervention	μg/L (Mean)
Fast-track Surgery	0.6275
Traditional Surgery	0.7280

The Total Cost (RMB)

The total cost from hospitalization (NCT02687412)
Timeframe: 12 month

Intervention	RMB (Mean)
Fast-track Surgery	38882.44
Traditional Surgery	42864.12

Trials

4 trials available for bupivacaine and Fatigue

Article	Year
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation. Lancet (London, England), 1995, Mar-25, Volume: 345, Issue:8952 Topics: Adenocarcinoma; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Bupivacaine; Colo	1995
The effect of balanced analgesia on early convalescence after major orthopaedic surgery. Acta anaesthesiologica Scandinavica, 1994, Volume: 38, Issue:4 Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesia; Analgesia, Epidural; Anesthesia, Epidural; Anesth	1994
Effect of combined prednisolone, epidural analgesia, and indomethacin on the systemic response after colonic surgery. Archives of surgery (Chicago, Ill. : 1960), 1992, Volume: 127, Issue:3 Topics: Acetaminophen; Activities of Daily Living; Aged; Analgesia, Epidural; Body Temperature; Bupivacaine;	1992
Interpleural catheter for analgesia after cholecystectomy: the surgical perspective. The Australian and New Zealand journal of surgery, 1990, Volume: 60, Issue:9 Topics: Adult; Aged; Bupivacaine; Cholecystectomy; Clinical Trials as Topic; Fatigue; Female; Humans; Infusi	1990

Other Studies

1 other study available for bupivacaine and Fatigue

Article	Year
Convalescence and hospital stay after colonic surgery with balanced analgesia, early oral feeding, and enforced mobilisation. The European journal of surgery = Acta chirurgica, 1995, Volume: 161, Issue:4 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Bupivacaine; Colectomy; Convales	1995