bupivacaine has been researched along with Eye Diseases in 13 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Eye Diseases: Diseases affecting the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Two patients in the levobupivacaine group experienced serious adverse events, but neither was considered related to the study medication." | 2.71 | The efficacy and safety of 0.75% levobupivacaine vs 0.75% bupivacaine for peribulbar anaesthesia. ( Birt, DJ; Cummings, GC, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (38.46) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Bartholomew, KJ | 1 |
| Smith, LJ | 1 |
| Bentley, E | 1 |
| Lasarev, MR | 1 |
| Birt, DJ | 1 |
| Cummings, GC | 1 |
| Ghosh, YK | 1 |
| Goodall, KL | 1 |
| Chin, GN | 1 |
| Almquist, HT | 1 |
| Davis, DB | 1 |
| Mandel, MR | 1 |
| Saini, JS | 1 |
| Roysarkar, TK | 1 |
| Grewal, SP | 1 |
| Sharma, A | 1 |
| Bohlender, T | 1 |
| Weindler, J | 1 |
| Schroeder, P | 1 |
| Ruprecht, KW | 1 |
| Demirok, A | 1 |
| Simşek, S | 1 |
| Cinal, A | 1 |
| Yaşar, T | 1 |
| Sharma, T | 1 |
| Gopal, L | 1 |
| Shanmugam, MP | 1 |
| Bhende, P | 1 |
| George, J | 1 |
| Samanta, TK | 1 |
| Mukesh, BN | 1 |
| Schlegel, HJ | 1 |
| Bernardczyk, J | 1 |
| Smith, RB | 2 |
| Everett, WG | 1 |
| Linn, JG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Retrobulbar Block on Bi-Hemispheric Cerebral Oxygen Saturation and Early Period Postoperative Cognitive Functions With Lidocaine and Levobupivacaine in Elderly Patients With Ophthalmic Surgery[NCT03189329] | Phase 4 | 66 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| A Randomized Trial of Buffered vs Nonbuffered Lidocaine With Epinephrine for Cervical Loop Excision[NCT01405768] | Phase 2 | 56 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"A Likert visual analog scale will be used to document each study participant's level of pain experienced during injection of the cervical block.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Lidocaine Arm | 25 |
| Buffered Lidocaine | 19 |
"A Likert visual analog scale will be used to document each study participant's level of pain experienced during injection of the cervical block.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of the procedure
| Intervention | units on a scale (Median) |
|---|---|
| Lidocaine Arm | 26 |
| Buffered Lidocaine | 18 |
"A Likert visual analog scale will be used to determine the overall pain experienced by each study participant including injection pain, procedural pain, and cramping.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of procedure
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Injection pain | Procedure pain | Cramping pain | |
| Buffered Lidocaine | 19 | 19 | 18 |
| Lidocaine Arm | 25 | 27 | 19 |
"A Likert visual analog scale will be used to determine the overall pain experienced by each study participant including injection pain, procedural pain, and cramping.~Within 30 minutes of completion of the procedure and after instruction by the investigators, women reported the intensity of their pain by marking single lines across 100-mm Likert visual analog scales. Scales did not include hashmarks or internal descriptors, as these have been shown to bias responses and diminish reliability.~Patient marks on 100-mm Likert scale lines were measured, and a score was determined by the length marked off in millimeters. Patients who wrote no pain were considered to have marked 0 mm." (NCT01405768)
Timeframe: Within 30 minutes of completion of procedure
| Intervention | units on a scale (Median) | ||
|---|---|---|---|
| Injection pain | Procedure pain | Cramping pain | |
| Buffered Lidocaine | 18 | 13 | 14 |
| Lidocaine Arm | 26 | 25 | 19 |
1 review available for bupivacaine and Eye Diseases
| Article | Year |
|---|---|
Physiology and pharmacology of local anesthetic agents.
Topics: Administration, Topical; Amides; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Ce | 1973 |
6 trials available for bupivacaine and Eye Diseases
| Article | Year |
|---|---|
The efficacy and safety of 0.75% levobupivacaine vs 0.75% bupivacaine for peribulbar anaesthesia.
Topics: Aged; Aged, 80 and over; Anesthesia, Conduction; Anesthetics, Local; Bupivacaine; Double-Blind Metho | 2003 |
Postoperative pain relief in vitreoretinal surgery with subtenon Bupivacaine 0.75%.
Topics: Analgesia; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Connective Tissue; Double-Blind Metho | 2005 |
Bupivacaine and lidocaine retrobulbar anesthesia. A double-blind clinical study.
Topics: Adult; Aged; Anesthesia, Local; Bupivacaine; Clinical Trials as Topic; Double-Blind Method; Epinephr | 1983 |
[Transcutaneous or transconjunctival peribulbar anesthesia?].
Topics: Anesthesia, Local; Bupivacaine; Conjunctiva; Eye Diseases; Humans; Injections; Injections, Intraderm | 1997 |
Peribulbar anesthesia: one versus two injections.
Topics: Anesthesia, Local; Anesthetics, Local; Bupivacaine; Drug Combinations; Eye Diseases; Eye Movements; | 1997 |
Comparison of pH-adjusted bupivacaine with a mixture of non-pH-adjusted bupivacaine and lignocaine in primary vitreoretinal surgery.
Topics: Alkalies; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Double-Blind Me | 2002 |
6 other studies available for bupivacaine and Eye Diseases
| Article | Year |
|---|---|
Retrospective analysis of complications associated with retrobulbar bupivacaine in dogs undergoing enucleation surgery.
Topics: Anesthetics, Local; Animals; Bupivacaine; Dog Diseases; Dogs; Drug Administration Routes; Eye Diseas | 2020 |
Efficacy and complication rate of 16,224 consecutive peribulbar blocks. A prospective multicenter study.
Topics: Aged; Anesthesia, Local; Bupivacaine; Eye Diseases; Eye Movements; Female; Humans; Hyaluronoglucosam | 1994 |
Efficacy and timed sequence analyses of modified single-injection peribulbar anesthesia.
Topics: Anesthesia, Local; Bupivacaine; Eye Diseases; Eyelids; Humans; Lidocaine; Massage; Muscles; Oculomot | 1993 |
[Long-acting local anesthetics - an enrichment in ophthalmosurgery? (author's transl)].
Topics: Anesthetics, Local; Body Temperature; Bupivacaine; Delayed-Action Preparations; Eye Diseases; Humans | 1977 |
[Anesthesia in ophthalmology].
Topics: Acupuncture Analgesia; Acupuncture Therapy; Anesthesia, General; Anesthesia, Local; Bupivacaine; Eye | 1989 |
Retrobulbar injection of bupivacaine (marcaine) for anesthesia and akinesia.
Topics: Adult; Aged; Anesthesia, Local; Anesthesia, Obstetrical; Bupivacaine; Cataract Extraction; Ciliary B | 1974 |