bupivacaine and Entrapment Neuropathies

bupivacaine has been researched along with Entrapment Neuropathies in 30 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Research

Studies (30)

Authors

Clinical Trials (3)

Trial Overview

Trial Outcomes

Need for Intervention for Postoperative Pain

Need for intervention through the use of trigger point injection, referral to pelvic floor physical therapy, or reoperation (NCT02037061)
Timeframe: 6-weeks

Overall Pain Beyond Day of Discharge

Pain measured using the pain numeric rating scale from 0-10 (0=no pain, 10= worst pain imaginable) (NCT02037061)
Timeframe: 6 weeks

Postoperative Gluteal Pain

Pain measured using a pain numeric rating scale from 0 to 10 (0=no pain, 10= worst pain imaginable) (NCT02037061)
Timeframe: 6-weeks

Change in Pelvic Flore Disability Index - 20 (PFDI-20) Scores From Baseline to 12 Months

"Symptomatic success was assessed by the pelvic floor disability index (PFDI-20) questionnaire. The PFDI-20 has 20 items within 3 sub-scales of symptoms (total of 20 items). Each item produces a response of 0 to 4, the average response in each sub-scale is multiplied by 25 to obtain the sub-scale score (range 0 to 100). The total score is the sum of the three sub-scale scores with a range of 0-300. Higher value for a time-point score indicates a greater degree of symptom bother.~The difference in scores across the study time-points was calculated by subtracting the total score at baseline from the score at 12 months post-operation. A negative value for the difference in scores from baseline to 12 months indicates symptom improvement, where the more negative the difference in score is the greater the improvement in symptoms." (NCT03565640)
Timeframe: Baseline and Month 12

Change in Symptomatic Success - PFIQ-7 Scores

"Symptomatic success will be assessed by the Pelvic Floor Impact Questionnaire - 7 (PFIQ-7). The PFIQ-7 has 7 items for each of 3 sub-scales (total of 21 items). Each item produces a response of 0 to 3, the average response in each sub-scale is multiplied by 100/3 to obtain the total scale score (range 0 to 100). The total score is the sum of the three sub-scale scores with a range of 0-300. Higher value for a time-point score indicates a greater degree of symptom bother.~The difference in scores across the study time-points was calculated by subtracting the total score at baseline from the score at 12 months post-operation. A negative value for the difference in scores from baseline to 12 months indicates symptom improvement, where the more negative the difference in score is the greater the improvement in symptoms." (NCT03565640)
Timeframe: Baseline and Month 12

POP-Q Stage Score

The stage is assigned as follows: 0 if there is no prolapse at all, 1 if there is prolapse but the leading point is not within 1cm of the hymen, 2 if the leading point is within 1 cm of the hymen (from 1cm within the hymen to 1cm beyond the hymen), 3 if the leading point is more than 1cm from the hymen but less than 2cm from being completely prolapsed, and 4 if the leading point is within 2cm of being complete prolapsed. Therefore higher POP-Q stages correlate to a worse degree of prolapse than lower POP-Q stages. (NCT03565640)
Timeframe: at 12 MONTHS

Change in Buttock and Posterior Thigh Pain

This will be assessed using the numeric rating scale (NRS). The score is 0-10, with higher scores denoting a greater degree of pain. (NCT03565640)
Timeframe: postoperative 12 month

Reviews

3 reviews available for bupivacaine and Entrapment Neuropathies

Trials

4 trials available for bupivacaine and Entrapment Neuropathies

Other Studies

24 other studies available for bupivacaine and Entrapment Neuropathies