bupivacaine has been researched along with Emesis, Postoperative in 168 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We concluded that the addition of nalbuphine to intrathecal bupivacaine plus morphine significantly reduced the incidence and severity of postoperative nausea and vomiting and pruritus without affecting analgesic potency." | 9.30 | Effect of adding nalbuphine to intrathecal bupivacaine with morphine on postoperative nausea and vomiting and pruritus after elective cesarean delivery: a randomized double blinded study. ( Abdelaziz, MR; Aly, MG; Ibrahim, AS; Thabet, ME, 2019) |
| "This study evaluated the analgesic efficacy of dexmedetomidine in combination with bupivacaine for single-shot paravertebral block (PVB) in patients undergoing major breast cancer surgery." | 9.22 | Efficacy of dexmedetomidine as an adjuvant in paravertebral block in breast cancer surgery. ( Kalra, B; Kaur, N; Mohta, M; Sethi, AK, 2016) |
| "These data provide some evidence that a preoperative subtenon block with bupivacaine combined with general anesthesia allows efficient control of postoperative pain as well as a reduction in the incidence of OCR and PONV in young children undergoing strabismus surgery." | 9.20 | SUBTENON BUPIVACAINE INJECTION FOR POSTOPERATIVE PAIN RELIEF FOLLOWING PEDIATRIC STRABISMUS SURGERY: A RANDOMIZED CONTROLLED DOUBLE BLIND TRIAL. ( Abdelaziz, HM; Bakr, RH, 2015) |
| "In the absence of any study on the use of bupivacaine as a long acting local anesthetic for the purpose of inducing preemptive analgesia in patients undergoing inguinal hernia repair under spinal anesthesia, this study was conducted to provide some evidence for possible benefits of such practice." | 9.17 | The effect of preemptive analgesia with bupivacaine on postoperative pain of inguinal hernia repair under spinal anesthesia: a randomized clinical trial. ( Akhondzadeh, R; Nazaree, E; Nesioonpour, Sh; Pipelzadeh, MR; Rezaee, S; Soleymani, M, 2013) |
| "To evaluate the postoperative analgesia after surgical site infiltration with bupivacaine or ketamine in children undergoing cleft palate surgery." | 9.17 | A randomized study of surgical site infiltration with bupivacaine or ketamine for pain relief in children following cleft palate repair. ( Bhardwaj, N; Jha, AK; Mahajan, JK; Sharma, RK; Yaddanapudi, S, 2013) |
| "Caudal bupivacaine is widely used for inguinal hernia repair in children, but often cannot totally eliminate responses to hernial sac traction." | 9.17 | Caudal dexmedetomidine combined with bupivacaine inhibit the response to hernial sac traction in children undergoing inguinal hernia repair. ( Huang, DY; Liu, YX; Luo, T; Wang, GH; Xiang, Q; Zhao, YL; Zhong, L, 2013) |
| "kg(-1) added to bupivacaine significantly improves the quality of intraoperative analgesia and prolongs postoperative analgesia in children undergoing inguinal hernia repair with spinal anesthesia." | 9.14 | Effects of intrathecal fentanyl on quality of spinal anesthesia in children undergoing inguinal hernia repair. ( Apiliogullari, S; Duman, A; Duman, I, 2010) |
| "Thoracic epidural neostigmine enables faster restoration of bowel sounds and shortens duration of postoperative ileus after abdominal aortic surgery." | 9.13 | A prospective randomized double-blind study to determine the effect of thoracic epidural neostigmine on postoperative ileus after abdominal aortic surgery. ( Bozdogan, N; Caliskan, E; Gulcan, O; Sener, M; Turkoz, A; Turkoz, R, 2008) |
| "Propofol sedation with local sub-Tenon's injection of lidocaine/mercaine is recommended for the induction and maintenance of anaesthesia during unilateral or bilateral strabismus surgery in adults." | 9.12 | Combined propofol sedation with sub-Tenon's lidocaine/mercaine infusion for strabismus surgery in adults. ( Axer-Siegel, R; Bachar, M; Friling, R; Katz, J; Snir, M; Weinberger, D, 2007) |
| "Caudal neostigmine 2 micro g/kg provides postoperative analgesia comparable to caudal bupivacaine in children undergoing hypospadias repair surgery." | 9.10 | Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children. ( Abdulatif, M; El-Sanabary, M, 2002) |
| "To assess the safety and efficacy of ondansetron for prevention of pruritus, nausea and vomiting after cesarean delivery with intrathecal sufentanil-morphine." | 9.10 | Prophylactic ondansetron is effective in the treatment of nausea and vomiting but not on pruritus after cesarean delivery with intrathecal sufentanil-morphine. ( Chalhoub, V; Haddad, F; Hayek, G; Madi-Jebara, S; Yazigi, A, 2002) |
| "Intraoperative hypotension is a common and potentially deleterious event in elderly patients undergoing spinal anaesthesia for repair of hip fractures." | 6.71 | Spinal-induced hypotension in elderly patients with hip fracture. A comparison of glucose-free bupivacaine with glucose-free bupivacaine and fentanyl. ( Gillespie, G; Martyr, JW; Stannard, KJ, 2005) |
| "77%, p = 0." | 6.69 | Effects of peribulbar bupivacaine as an adjunct to general anaesthesia on peri-operative outcome following retinal detachment surgery. ( Madan, R; Sadhasivam, S; Shende, D, 2000) |
| " Patients in the dexamethasone group received less morphine at 24 h, had significantly less postoperative nausea and vomiting at 2 h and 24 h, and had increased blood glucose at 24 h." | 5.69 | Sensory block duration after spinal anaesthesia supplemented with intravenous dexamethasone: a randomised controlled double-blinded trial. ( Albrecht, E; Bashawyah, A; Bikfalvi, A; Gonvers, E; Hofmann, G; Rossel, JB, 2023) |
| "We concluded that the addition of nalbuphine to intrathecal bupivacaine plus morphine significantly reduced the incidence and severity of postoperative nausea and vomiting and pruritus without affecting analgesic potency." | 5.30 | Effect of adding nalbuphine to intrathecal bupivacaine with morphine on postoperative nausea and vomiting and pruritus after elective cesarean delivery: a randomized double blinded study. ( Abdelaziz, MR; Aly, MG; Ibrahim, AS; Thabet, ME, 2019) |
| "This study evaluated the analgesic efficacy of dexmedetomidine in combination with bupivacaine for single-shot paravertebral block (PVB) in patients undergoing major breast cancer surgery." | 5.22 | Efficacy of dexmedetomidine as an adjuvant in paravertebral block in breast cancer surgery. ( Kalra, B; Kaur, N; Mohta, M; Sethi, AK, 2016) |
| "These data provide some evidence that a preoperative subtenon block with bupivacaine combined with general anesthesia allows efficient control of postoperative pain as well as a reduction in the incidence of OCR and PONV in young children undergoing strabismus surgery." | 5.20 | SUBTENON BUPIVACAINE INJECTION FOR POSTOPERATIVE PAIN RELIEF FOLLOWING PEDIATRIC STRABISMUS SURGERY: A RANDOMIZED CONTROLLED DOUBLE BLIND TRIAL. ( Abdelaziz, HM; Bakr, RH, 2015) |
| " This prospective, randomized, double blind study was carried out to compare the effectiveness of a combination of dexamethasone and ondansetron with dexamethasone alone for prevention of postoperative nausea and vomiting (PONV) following intrathecal morphine injection for caesarean section." | 5.19 | Dexamethasone versus a combination of dexamethasone and ondansetron as prophylactic antiemetic in patients receiving intrathecal morphine for caesarean section. ( Imeh, A; Olaniyi, O; Omotola, O; Simeon, O, 2014) |
| "In the absence of any study on the use of bupivacaine as a long acting local anesthetic for the purpose of inducing preemptive analgesia in patients undergoing inguinal hernia repair under spinal anesthesia, this study was conducted to provide some evidence for possible benefits of such practice." | 5.17 | The effect of preemptive analgesia with bupivacaine on postoperative pain of inguinal hernia repair under spinal anesthesia: a randomized clinical trial. ( Akhondzadeh, R; Nazaree, E; Nesioonpour, Sh; Pipelzadeh, MR; Rezaee, S; Soleymani, M, 2013) |
| "To evaluate the postoperative analgesia after surgical site infiltration with bupivacaine or ketamine in children undergoing cleft palate surgery." | 5.17 | A randomized study of surgical site infiltration with bupivacaine or ketamine for pain relief in children following cleft palate repair. ( Bhardwaj, N; Jha, AK; Mahajan, JK; Sharma, RK; Yaddanapudi, S, 2013) |
| "Caudal bupivacaine is widely used for inguinal hernia repair in children, but often cannot totally eliminate responses to hernial sac traction." | 5.17 | Caudal dexmedetomidine combined with bupivacaine inhibit the response to hernial sac traction in children undergoing inguinal hernia repair. ( Huang, DY; Liu, YX; Luo, T; Wang, GH; Xiang, Q; Zhao, YL; Zhong, L, 2013) |
| " In this randomized, prospective, double-blinded study, we evaluated the incidence of side-effects such as changes in arterial pressure, postoperative nausea, vomiting, and pruritus in patients admitted for thoracic surgery during continuous thoracic epidural infusion using levobupivacaine and sufentanil mixture in three different volumes." | 5.14 | Thoracic epidural analgesia in post-thoracotomy patients: comparison of three different concentrations of levobupivacaine and sufentanil. ( Cammarota, G; Cecci, G; Della Corte, F; Ferrante, D; Mendola, C; Oldani, E; Vaschetto, R, 2009) |
| "The development of hypotension after spinal block in subjects undergoing cesarean section was not prevented despite low-dose (4 mg) bupivacaine plus 25 microg fentanyl, but the severity of maternal hypotension, and the number of ephedrine treatments and the total dose of ephedrine were decreased." | 5.14 | Is there an advantage in using low-dose intrathecal bupivacaine for cesarean section? ( Erdogan, H; Kaya, S; Turhanoglu, S, 2009) |
| "The aim of our study was to investigate the block characteristics of intrathecal hyperbaric bupivacaine 7, 8, or 9 mg administered during combined spinal-epidural anesthesia for cesarean delivery and to elucidate the dose that produces adequate sensory blockade for surgery while minimizing the incidence of hypotension, high neuroblockade, and the need for intraoperative epidural supplementation." | 5.14 | A randomized comparison of low doses of hyperbaric bupivacaine in combined spinal-epidural anesthesia for cesarean delivery. ( Leo, S; Lim, Y; Sia, AT; Sng, BL, 2009) |
| "kg(-1) added to bupivacaine significantly improves the quality of intraoperative analgesia and prolongs postoperative analgesia in children undergoing inguinal hernia repair with spinal anesthesia." | 5.14 | Effects of intrathecal fentanyl on quality of spinal anesthesia in children undergoing inguinal hernia repair. ( Apiliogullari, S; Duman, A; Duman, I, 2010) |
| "Thoracic epidural neostigmine enables faster restoration of bowel sounds and shortens duration of postoperative ileus after abdominal aortic surgery." | 5.13 | A prospective randomized double-blind study to determine the effect of thoracic epidural neostigmine on postoperative ileus after abdominal aortic surgery. ( Bozdogan, N; Caliskan, E; Gulcan, O; Sener, M; Turkoz, A; Turkoz, R, 2008) |
| " Compared to hyperbaric bupivacaine, the combination of plain and hyperbaric bupivacaine provided a marked decrease in the incidence of hypotension (13." | 5.13 | Spinal anesthesia with sequential administration of plain and hyperbaric bupivacaine provides satisfactory analgesia with hemodynamic stability in cesarean section. ( Alici, HA; Borekci, B; Cesur, M; Erdem, AF; Silbir, F, 2008) |
| "4 mg, with significantly less pruritus when combined with low-dose bupivacaine." | 5.13 | Intrathecal morphine in anesthesia for cesarean delivery: dose-response relationship for combinations of low-dose intrathecal morphine and spinal bupivacaine. ( Aksu, H; Girgin, NK; Gulhan, N; Gurbet, A; Turker, G, 2008) |
| " The addition of clonidine 2 microg/kg to bupivacaine provides a prolonged anesthetic action but may be associated with hypotension." | 5.12 | Clonidine 1 microg/kg is a safe and effective adjuvant to plain bupivacaine in spinal anesthesia in adolescents. ( Abdelaziz, AB; Chattaoui, O; Kaabachi, O; Kokki, H; Ouezini, R; Zarghouni, A, 2007) |
| "Intrathecal morphine (ITM) is frequently associated with side effects such as postoperative nausea and vomiting (PONV) and pruritus." | 5.12 | Impact of Transversus Abdominis Plane Block With Bupivacaine or Ropivacaine Versus Intrathecal Morphine on Opioid-related Side Effects After Cesarean Delivery: A Meta-analysis of Randomized Controlled Trials. ( Chang, XY; Huang, JY; Wang, LZ; Xia, F, 2021) |
| "Propofol sedation with local sub-Tenon's injection of lidocaine/mercaine is recommended for the induction and maintenance of anaesthesia during unilateral or bilateral strabismus surgery in adults." | 5.12 | Combined propofol sedation with sub-Tenon's lidocaine/mercaine infusion for strabismus surgery in adults. ( Axer-Siegel, R; Bachar, M; Friling, R; Katz, J; Snir, M; Weinberger, D, 2007) |
| " We studied 60 patients scheduled for breast cancer surgery randomly given single-injection PVB at T3 with bupivacaine 5 mg/mL (1." | 5.11 | Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy. ( Bachmann, MS; Kairaluoma, PM; Korpinen, AK; Pere, PJ; Rosenberg, PH, 2004) |
| "Demography, upper sensory block, visual analog scale scores at rest and after coughing, levobupivacaine and rescue morphine consumption, motor blockade, hemodynamics, postoperative nausea and vomiting, sedation, and patient satisfaction were recorded within the first 48 hours." | 5.11 | Comparison of 2 concentrations of levobupivacaine in postoperative patient-controlled epidural analgesia. ( Bardiau, F; Boogaerts, JG; Dernedde, M; Stadler, M, 2005) |
| "To test whether prophylactic neural blockade of noziceptive afferents or antiemetics diminutes postoperative nausea and vomiting (PONV) we studied in a randomised, prospective, and ouble-blind fashion 102 patients receiving implantation of an episcleral radioactive applicator for treatment of ocular malignant melanoma during remifentanil-propofol-anaesthesia." | 5.10 | [Blocking nociceptive afferents by retrobulbar bupivacaine does not decrease nausea and vomiting after propofol-remifentanil anaesthesia]. ( Apfel, CC; Armbruster, W; Bornfeld, N; Müller, D; Peters, J; Unkel, W, 2003) |
| "Caudal neostigmine 2 micro g/kg provides postoperative analgesia comparable to caudal bupivacaine in children undergoing hypospadias repair surgery." | 5.10 | Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children. ( Abdulatif, M; El-Sanabary, M, 2002) |
| "In the sub-Tenon's bupivacaine group, there was a significant reduction in the perioperative opioid use and a reduction in the frequency of bradycardia and hypertensive episodes, defined as a rise > 25% of baseline for a duration of > 3 min." | 5.10 | Sub-Tenon's block reduces both intraoperative and postoperative analgesia requirement in vitreo-retinal surgery under general anaesthesia. ( Farmery, AD; Rahman, R; Rosen, P; Shlugman, D, 2003) |
| "To assess the safety and efficacy of ondansetron for prevention of pruritus, nausea and vomiting after cesarean delivery with intrathecal sufentanil-morphine." | 5.10 | Prophylactic ondansetron is effective in the treatment of nausea and vomiting but not on pruritus after cesarean delivery with intrathecal sufentanil-morphine. ( Chalhoub, V; Haddad, F; Hayek, G; Madi-Jebara, S; Yazigi, A, 2002) |
| "Postsurgical analgesia and the incidence of fentanyl-related complications, such as nausea/vomiting, somnolence, pruritus, and respiratory depression, were assessed for 24 hours postoperatively." | 5.09 | Additional droperidol, not butorphanol, augments epidural fentanyl analgesia following anorectal surgery. ( Ai, K; Kotake, Y; Matsumoto, M; Morisaki, H; Takeda, J, 2000) |
| "Intrathecal morphine (ITM) combined with bupivacaine spinal anesthesia can improve postoperative pain, but has potential side effects of postoperative nausea/vomiting (PONV) and pruritus." | 3.88 | Does Intrathecal Morphine in Spinal Anesthesia Have a Role in Modern Multimodal Analgesia for Primary Total Joint Arthroplasty? ( Aleshi, P; Cheah, JW; Hansen, EN; Sing, DC; Vail, TP, 2018) |
| "A prospective study was conducted on 20 patients undergoing strabismus surgery using contact topical anesthesia and sedation with remifentanil." | 3.81 | Contact topical anesthesia for strabismus surgery in adult patients. ( Fernández-Tirado, FJ; García-Martín, E; Gil-Arribas, LM; Peña-Calvo, P; Sanjuan-Villarreal, A; Vallés-Torres, J, 2015) |
| "Tramadol was optimal in pain control, and dexamethasone also afforded good pain control with low incidences of nausea and vomiting." | 3.01 | The efficacy and safety of peri-tonsillar administrated agents on pain treatment after pediatric tonsillectomy: A network meta-analysis. ( Basurrah, MA; Hwang, SH; Kim, DH; Kim, SW, 2023) |
| "The secondary outcome was the postoperative pain scores." | 2.90 | A randomized controlled trial on analgesic effect of repeated Quadratus Lumborum block versus continuous epidural analgesia following laparoscopic nephrectomy. ( Aditianingsih, D; Anasy, N; Mochtar, CA; Tantri, AR, 2019) |
| "Morphine consumption was significantly lower in Group 1 than in Group 2 at the 2nd, 6th and 24th hours (P<0." | 2.84 | Ultrasound-guided transversus abdominis plane block for postoperative analgesia in living liver donors: A prospective, randomized, double-blinded clinical trial. ( Aydogan, MS; Colak, C; Durmus, M; Erdogan, MA; Kıtlık, A; Ozgul, U; Toprak, HI; Ucar, M, 2017) |
| "Use of SB combined with general anesthesia in patients undergoing vitreoretinal surgery reduces postoperative analgesic requirements and complications such as intraoperative OCR and PONV." | 2.82 | Subtenon block combined with general anesthesia for vitreoretinal surgery improves postoperative analgesia in adult: a randomized controlled trial. ( Abdelhalim, AA; Abouammoh, MA; Al-Zahrani, TA; Elzoughari, I; Mohamed, EA; Mustafa, M, 2016) |
| "The incidence of postoperative vomiting occurred in 2 patients (3." | 2.79 | Comparative hemodynamic advantages of subarachnoid administration of atypical and non-atypical opioids. ( Afolayan, JM; Amadasun, FE; Areo, PO; Fadare, JO; Olajumoke, TO, 2014) |
| "Propofol was infused at a dose determined by a modified Dixon's up-and-down method." | 2.79 | Intrathecal fentanyl decreases the optimal effect site concentration of propofol during spinal anaesthesia. ( Kim, JS; Kim, JY; Kim, MK; Kim, SH; Lee, JS, 2014) |
| "The morphine consumption was significantly lower in the L group at h6, h8 and h12 (considering both total intake and each request)." | 2.78 | [Single-dose intraincisional levobupivacaine infiltration in caesarean postoperative analgesia: a placebo-controlled double-blind randomized trial]. ( Chapelle, C; Chauleur, C; Corsini, T; Cuvillon, P; Forgeot, A; Seffert, P, 2013) |
| "Clonidine has the potential to significantly prolong the duration of caudal epidural anesthesia." | 2.76 | Effect of epidural clonidine on minimum local anesthetic concentration (ED50) of levobupivacaine for caudal block in children. ( Alberighi, OD; Disma, N; Frawley, G; Mameli, L; Montobbio, G; Pistorio, A; Tuo, P, 2011) |
| " This dose-response study suggests that doses of intrathecal bupivacaine less than 10 mg may not adequately ensure successful intraoperative anesthesia." | 2.76 | ED(50) and ED(95) of intrathecal bupivacaine in morbidly obese patients undergoing cesarean delivery. ( Atkinson Ralls, L; Carvalho, B; Collins, J; Drover, DR; Riley, ET, 2011) |
| "Frequency of pruritus and postoperative nausea and vomiting (PONV) were also recorded." | 2.75 | Efficacy of intrathecal morphine with epidural ropivacaine infusion for postcesarean analgesia. ( Hirai, H; Iwasaki, H; Mikuni, I; Takahata, O; Toyama, Y, 2010) |
| "Tramadol consumption was lower (P < 0." | 2.75 | Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty. ( Ates, Y; Aysu Salviz, E; Darcin, K; Kazak Bengisun, Z; Suer, H, 2010) |
| " Dosed at a maximum rate of 0." | 2.74 | Continuous incisional infusion of local anesthetic in pediatric patients following open heart surgery. ( Burke, RP; Decampli, W; Felix, DE; Hannan, RL; Madril, D; Munro, HM; Rusinowski, L; Salvaggio, J; Tirotta, CF; Tyler, C, 2009) |
| " Study variables included pain intensity on a visual analog scale every 4 hours, need for rescue analgesia (morphine), complications and adverse events within 5 postoperative days." | 2.74 | [Epidural analgesia versus femoral or femoral-sciatic nerve block after total knee replacement: comparison of efficacy and safety]. ( Bartrons Vilarnau, R; Bisbe Vives, E; Castillo Monsegur, J; Escolano Villén, F; Ginés Cespedosa, A; Montes Pérez, A; Santiveri Papiol, X, 2009) |
| "The presence of postoperative nausea and vomiting (PONV), pruritus and respiratory depression were recorded." | 2.73 | The effect of intravenous administration of dexamethasone on postoperative pain, nausea, and vomiting after intrathecal injection of meperidine. ( Akbarian-Tefaghi, N; Esfehani, F; Movafegh, A; Navi, A; Sadeghi, M; Soroush, AR, 2007) |
| "The hearing loss was unilateral in two and bilateral in four patients." | 2.73 | Hearing loss after spinal anesthesia: the effect of different infusion solutions. ( Iseri, M; Karaca, B; Solak, M; Toker, K; Yildiz, TS, 2007) |
| "The challenge of preempting postoperative pain continues and will require further investigation." | 2.73 | Prospective, double-blinded, randomized, placebo-controlled comparison of local anesthetic and nonsteroidal anti-inflammatory drugs for postoperative pain management after laparoscopic surgery. ( Heniford, BT; Hope, W; Kercher, K; Lincourt, A; Newcomb, W; Schmelzer, T; Sing, R, 2007) |
| " The overall incidence of adverse events was low and consisted primarily of technical problems and postoperative nausea and vomiting." | 2.73 | Safety and efficacy of patient controlled epidural analgesia following pediatric spinal surgery. ( Ceroni, D; Greenberg, RS; Habre, W; Kaelin, A; Meyer, PA; Saudan, S; von Ungern-Sternberg, BS, 2008) |
| "A less frequent incidence of postoperative nausea, but not vomiting, was also found during 4-24 h in group L compared with group P (P < 0." | 2.71 | Postoperative pain after abdominal hysterectomy: a double-blind comparison between placebo and local anesthetic infused intraperitoneally. ( Axelsson, K; Crafoord, K; Gupta, A; Perniola, A; Rawal, N; Thörn, SE, 2004) |
| "Monitoring for pain, sedation, postoperative nausea/vomiting, dizziness, and pruritus was performed by anesthesiologists blinded to the study allocation." | 2.71 | Caudal additives in pediatrics: a comparison among midazolam, ketamine, and neostigmine coadministered with bupivacaine. ( Acharya, A; Kumar, P; Pan, AK; Rudra, A, 2005) |
| "Spinal anesthesia with supplemental epidural clonidine in combination with incision site subcutaneous bupivacaine was evaluated both intra- and postoperatively and compared with spinal anesthesia alone for lower lumbar spine procedures." | 2.71 | The effect of spinal bupivacaine in combination with either epidural clonidine and/or 0.5% bupivacaine administered at the incision site on postoperative outcome in patients undergoing lumbar laminectomy. ( Abodeely, A; Fluder, EM; Jellish, WS; Shea, J, 2003) |
| "No difference was observed in postoperative pain scores (visual analogue scale at rest and on coughing), or analgesic requirements during the first 24 postoperative hours between the four groups." | 2.71 | Prophylactic ip injection of bupivacaine and/or morphine does not improve postoperative analgesia after laparoscopic gynecologic surgery. ( Bedairia, K; Benifla, JL; Desmonts, JM; Keita, H; Le Bouar, V; Mantz, J; Porcher, R; Wachowska, B, 2003) |
| "Fentanyl 20 micro g was added to both local anesthetics, and the total volume was diluted to 3 mL with 0." | 2.71 | Subarachnoid small-dose bupivacaine versus lidocaine for cervical cerclage. ( Abramovitz, S; Beilin, Y; Bernstein, HH; Bodian, C; Hossain, S; Zahn, J, 2003) |
| "The ketamine group was administered a ketamine bolus and infusion during surgery." | 2.71 | Intraoperative intravenous ketamine in combination with epidural analgesia: postoperative analgesia after renal surgery. ( Karaman, H; Kararmaz, A; Kaya, S; Ozyilmaz, MA; Turhanoglu, S, 2003) |
| "The efficiency of bilateral paravertebral blockade combined with general anaesthesia (active) vs." | 2.71 | General anaesthesia combined with bilateral paravertebral blockade (T5-6) vs. general anaesthesia for laparoscopic cholecystectomy: a prospective, randomized clinical trial. ( Lönnqvist, PA; Naja, MZ; Ziade, MF, 2004) |
| "Patients with a high risk for postoperative nausea and vomiting received prophylaxis in the GA group." | 2.71 | A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with desflurane for outpatient knee arthroscopy. ( Jokela, RM; Korhonen, AM; Korttila, KT; Ravaska, P; Valanne, JV, 2004) |
| "Intraoperative hypotension is a common and potentially deleterious event in elderly patients undergoing spinal anaesthesia for repair of hip fractures." | 2.71 | Spinal-induced hypotension in elderly patients with hip fracture. A comparison of glucose-free bupivacaine with glucose-free bupivacaine and fentanyl. ( Gillespie, G; Martyr, JW; Stannard, KJ, 2005) |
| "To determine whether postoperative pain and nausea after evisceration surgery is better controlled with intraoperative retrobulbar ethanol or bupivacaine." | 2.70 | Comparison of retrobulbar analgesics for evisceration. ( Buffam, F; Dolman, PJ; Giligson, A, 2002) |
| " Eleven patients with normal renal function and eight patients with ESRD underwent pharmacokinetic analysis." | 2.70 | Levobupivacaine for axillary brachial plexus block: a pharmacokinetic and clinical comparison in patients with normal renal function or renal disease. ( Crews, JC; James, RL; Moss, J; Weller, RS, 2002) |
| "Retrobulbar anesthesia reduces postoperative pain." | 2.70 | [Additive retrobulbar anesthesia in surgery of retinal detachment with general anesthesia. Reduced postoperative pain and stress response]. ( Heiden, M; Heiligenhaus, A; Kawohl, C; Lösche, CC; Strunk, W, 2002) |
| " Peribulbar block appears to be a safe and useful analgesic technique for paediatric ophthalmic surgery." | 2.70 | Safety and efficacy of peribulbar block as adjunct to general anaesthesia for paediatric ophthalmic surgery. ( Deb, K; Dehran, M; Shende, D; Subramaniam, R; Tandon, R, 2001) |
| "A decrease in the rate of gastric emptying can delay resumption of enteral feeding, alter bioavailability of orally administered drugs, and result in larger residual gastric volumes, increasing the risk of nausea and vomiting." | 2.69 | Delayed postoperative gastric emptying following intrathecal morphine and intrathecal bupivacaine. ( Cooke, T; Duggan, F; Lydon, AM; Shorten, GD, 1999) |
| "125% to 0." | 2.69 | A comparison of two concentrations of bupivacaine and adrenaline with and without fentanyl in paediatric inguinal herniorrhaphy. ( Connelly, NR; Dwyer, M; Joshi, W; Kilaru, PR; Reuben, SS; Schwartz, D, 1999) |
| "Postoperative pain was evaluated by verbal rating scale." | 2.69 | Day-case laparoscopy: a comparison of prophylactic opioid, NSAID or local anesthesia for postoperative analgesia. ( Aypar, U; Coşkun, F; Salman, MA; Yücebaş, ME, 2000) |
| "77%, p = 0." | 2.69 | Effects of peribulbar bupivacaine as an adjunct to general anaesthesia on peri-operative outcome following retinal detachment surgery. ( Madan, R; Sadhasivam, S; Shende, D, 2000) |
| "Morphine was also associated with a significantly greater incidence of urinary retention than pethidine (p = 0." | 2.69 | Side-effects of epidural infusions of opioid bupivacaine mixtures. ( Gedney, JA; Liu, EH, 1998) |
| "The endpoints were postoperative pain, rescue analgesic requirement, and postoperative nausea and vomiting (PONV) during the immediate 24 h postoperative period." | 2.66 | The effect of bupivacaine on postoperative pain following thyroidectomy: a systematic review and meta-analysis. ( Chen, R; Jiang, Y; Li, Y; Liang, B; Xu, S; Ye, Y; Yu, M; Zhang, Z; Zou, Z, 2020) |
| "The efficacy of postoperative pain management is an important factor that influences the final outcome of total knee arthroplasty (TKA)." | 2.61 | The efficacy of liposomal bupivacaine compared with traditional peri-articular injection for pain control following total knee arthroplasty: an updated meta-analysis of randomized controlled trials. ( Li, M; Liu, Y; Shen, B; Wei, W; Zeng, J; Zeng, Y, 2019) |
| " However, adverse side effects of opioids include respiratory depression, urinary retention, pruritus, vomiting, nausea, constipation, and increased risk of falls." | 1.43 | Reducing Opioid Adverse Events: A Safe Way to Improve Outcomes. ( McCarus, SD; Redan, JA; Reeder, S; Wells, T, 2016) |
| " Only one previous study has reported adverse events of CPNB in a high number of pediatric cases." | 1.35 | Continuous peripheral nerve blocks for postoperative analgesia in children: feasibility and side effects in a cohort study of 339 catheters. ( Bringuier, S; Canaud, N; Capdevila, X; Dadure, C; Lubrano-Lavadera, JF; Raux, O; Rochette, A; Troncin, R, 2009) |
| "Pruritus was observed in 29% of patients and was more common in diplegia than quadriplegia (48% vs 12." | 1.30 | Epidural analgesia in children with cerebral palsy. ( Brenn, BR; Brislin, RP; Rose, JB, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (9.52) | 18.2507 |
| 2000's | 87 (51.79) | 29.6817 |
| 2010's | 55 (32.74) | 24.3611 |
| 2020's | 10 (5.95) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, JY | 1 |
| Wang, LZ | 1 |
| Chang, XY | 1 |
| Xia, F | 1 |
| Ryan, AC | 1 |
| Murrell, JC | 1 |
| Gurney, MA | 1 |
| Kim, DH | 1 |
| Kim, SW | 1 |
| Basurrah, MA | 1 |
| Hwang, SH | 1 |
| Bikfalvi, A | 1 |
| Hofmann, G | 1 |
| Bashawyah, A | 1 |
| Rossel, JB | 1 |
| Gonvers, E | 1 |
| Albrecht, E | 1 |
| Alansary, AM | 1 |
| Aziz, MM | 1 |
| Elbeialy, MAK | 1 |
| Poddar, KKD | 1 |
| Kumar, P | 2 |
| Hansda, U | 1 |
| Sethi, MK | 1 |
| Mishra, TS | 1 |
| Sasmal, PK | 1 |
| Singh, PK | 1 |
| Kumar, R | 1 |
| Gaballah, KM | 1 |
| Habeeb, RM | 1 |
| Abdallah, SI | 1 |
| Aditianingsih, D | 1 |
| Anasy, N | 1 |
| Tantri, AR | 1 |
| Mochtar, CA | 1 |
| Jiang, Y | 1 |
| Zhang, Z | 1 |
| Liang, B | 1 |
| Xu, S | 1 |
| Ye, Y | 1 |
| Chen, R | 1 |
| Li, Y | 1 |
| Yu, M | 1 |
| Zou, Z | 1 |
| Onishi, E | 1 |
| Murakami, M | 1 |
| Hashimoto, K | 1 |
| Kaneko, M | 1 |
| Cao, X | 1 |
| Pan, F | 1 |
| Cheah, JW | 1 |
| Sing, DC | 1 |
| Hansen, EN | 1 |
| Aleshi, P | 1 |
| Vail, TP | 1 |
| Ammar, A | 1 |
| Mahmoud, K | 1 |
| Kasemy, Z | 1 |
| Karaca, O | 1 |
| Pınar, HU | 1 |
| Arpacı, E | 1 |
| Dogan, R | 1 |
| Cok, OY | 1 |
| Ahiskalioglu, A | 2 |
| Gatherwright, J | 1 |
| Knackstedt, RW | 1 |
| Ghaznavi, AM | 1 |
| Bernard, S | 1 |
| Schwarz, G | 1 |
| Moreira, A | 1 |
| Gurunluoglu, R | 1 |
| Djohan, R | 1 |
| Ibrahim, AS | 1 |
| Aly, MG | 1 |
| Thabet, ME | 1 |
| Abdelaziz, MR | 1 |
| Jarruwale, P | 1 |
| Ingkanart, S | 1 |
| Panichkul, S | 1 |
| Uppal, V | 1 |
| Retter, S | 1 |
| Casey, M | 1 |
| Sancheti, S | 1 |
| Matheson, K | 1 |
| McKeen, DM | 1 |
| Liu, Y | 1 |
| Zeng, Y | 1 |
| Zeng, J | 1 |
| Li, M | 1 |
| Wei, W | 1 |
| Shen, B | 1 |
| Gürkan, Y | 1 |
| Aksu, C | 1 |
| Kuş, A | 1 |
| Yörükoğlu, UH | 1 |
| Jha, AK | 1 |
| Bhardwaj, N | 1 |
| Yaddanapudi, S | 1 |
| Sharma, RK | 1 |
| Mahajan, JK | 1 |
| Dostbil, A | 1 |
| Gursac Celik, M | 1 |
| Aksoy, M | 1 |
| Celik, EC | 1 |
| Alici, HA | 2 |
| Ozbey, I | 1 |
| Sharma, NR | 1 |
| Timalsena, P | 1 |
| S, DC | 1 |
| Lee, JS | 1 |
| Kim, JS | 1 |
| Kim, MK | 1 |
| Kim, SH | 3 |
| Kim, JY | 1 |
| Afolayan, JM | 1 |
| Olajumoke, TO | 1 |
| Amadasun, FE | 1 |
| Fadare, JO | 1 |
| Areo, PO | 1 |
| Tietje, T | 1 |
| Davis, AB | 1 |
| Rivey, MP | 1 |
| Vallés-Torres, J | 1 |
| García-Martín, E | 1 |
| Peña-Calvo, P | 1 |
| Sanjuan-Villarreal, A | 1 |
| Gil-Arribas, LM | 1 |
| Fernández-Tirado, FJ | 1 |
| Keller, DS | 1 |
| Ermlich, BO | 1 |
| Schiltz, N | 1 |
| Champagne, BJ | 1 |
| Reynolds, HL | 1 |
| Stein, SL | 1 |
| Delaney, CP | 1 |
| Imeh, A | 1 |
| Olaniyi, O | 1 |
| Simeon, O | 1 |
| Omotola, O | 1 |
| Purwar, B | 1 |
| Ismail, KM | 1 |
| Turner, N | 1 |
| Farrell, A | 1 |
| Verzune, M | 1 |
| Annappa, M | 1 |
| Smith, I | 1 |
| El-Gizawy, Z | 1 |
| Cooper, JC | 1 |
| Basaran, B | 1 |
| Basaran, A | 1 |
| Kozanhan, B | 1 |
| Kasdogan, E | 1 |
| Eryilmaz, MA | 1 |
| Ozmen, S | 1 |
| Bakr, RH | 1 |
| Abdelaziz, HM | 1 |
| Bayram, A | 1 |
| Doğan, M | 1 |
| Cihan, C | 1 |
| Karataş, D | 1 |
| Gökahmetoğlu, G | 1 |
| Özcan, I | 1 |
| Mohta, M | 1 |
| Kalra, B | 1 |
| Sethi, AK | 1 |
| Kaur, N | 1 |
| Abouammoh, MA | 1 |
| Abdelhalim, AA | 1 |
| Mohamed, EA | 1 |
| Elzoughari, I | 1 |
| Mustafa, M | 1 |
| Al-Zahrani, TA | 1 |
| Redan, JA | 1 |
| Wells, T | 1 |
| Reeder, S | 1 |
| McCarus, SD | 1 |
| Wu, HY | 1 |
| Gong, CA | 1 |
| Lin, SP | 1 |
| Chang, KY | 1 |
| Tsou, MY | 1 |
| Ting, CK | 1 |
| Kuang, MJ | 1 |
| Du, Y | 1 |
| Ma, JX | 1 |
| He, W | 1 |
| Fu, L | 1 |
| Ma, XL | 1 |
| Wang, X | 1 |
| Xiao, L | 1 |
| Wang, Z | 1 |
| Zhao, G | 1 |
| Ma, J | 1 |
| Kıtlık, A | 1 |
| Erdogan, MA | 2 |
| Ozgul, U | 1 |
| Aydogan, MS | 2 |
| Ucar, M | 1 |
| Toprak, HI | 1 |
| Colak, C | 2 |
| Durmus, M | 1 |
| Rawlani, V | 1 |
| Kryger, ZB | 1 |
| Lu, L | 1 |
| Fine, NA | 1 |
| El Shobary, HM | 1 |
| Sonbul, ZM | 1 |
| Schricker, TP | 1 |
| Mendola, C | 1 |
| Ferrante, D | 1 |
| Oldani, E | 1 |
| Cammarota, G | 1 |
| Cecci, G | 1 |
| Vaschetto, R | 1 |
| Della Corte, F | 1 |
| Siddiqi, R | 1 |
| Jafri, SA | 1 |
| Santiveri Papiol, X | 1 |
| Castillo Monsegur, J | 1 |
| Bisbe Vives, E | 1 |
| Ginés Cespedosa, A | 1 |
| Bartrons Vilarnau, R | 1 |
| Montes Pérez, A | 1 |
| Escolano Villén, F | 1 |
| Ghai, B | 1 |
| Ram, J | 1 |
| Makkar, JK | 1 |
| Wig, J | 1 |
| Kaushik, S | 1 |
| Sundarathiti, P | 1 |
| Ruananukul, N | 1 |
| Channum, T | 1 |
| Kitkunasathean, C | 1 |
| Mantay, A | 1 |
| Thammasakulsiri, J | 1 |
| Sodsee, W | 1 |
| Mariano, ER | 1 |
| Watson, D | 1 |
| Loland, VJ | 1 |
| Chu, LF | 1 |
| Cheng, GS | 1 |
| Mehta, SH | 1 |
| Maldonado, RC | 1 |
| Ilfeld, BM | 1 |
| Yilmaz, S | 1 |
| Demiraran, Y | 1 |
| Akkan, N | 1 |
| Yaman, H | 1 |
| Iskender, A | 1 |
| Güçlü, E | 1 |
| Oztürk, O | 1 |
| Karaaslan, K | 1 |
| Gulcu, N | 1 |
| Ozturk, H | 1 |
| Sarpkaya, A | 1 |
| Kocoglu, H | 1 |
| Tirotta, CF | 1 |
| Munro, HM | 1 |
| Salvaggio, J | 1 |
| Madril, D | 1 |
| Felix, DE | 1 |
| Rusinowski, L | 1 |
| Tyler, C | 1 |
| Decampli, W | 1 |
| Hannan, RL | 1 |
| Burke, RP | 1 |
| Parpaglioni, R | 1 |
| Baldassini, B | 1 |
| Barbati, G | 1 |
| Celleno, D | 1 |
| Turhanoglu, S | 2 |
| Kaya, S | 2 |
| Erdogan, H | 1 |
| Erdil, F | 1 |
| Bulut, S | 1 |
| Demirbilek, S | 1 |
| Gedik, E | 1 |
| Gulhas, N | 2 |
| Ersoy, MO | 2 |
| Dadure, C | 1 |
| Bringuier, S | 1 |
| Raux, O | 1 |
| Rochette, A | 1 |
| Troncin, R | 1 |
| Canaud, N | 1 |
| Lubrano-Lavadera, JF | 1 |
| Capdevila, X | 1 |
| Bhattacharya, P | 1 |
| Mandal, MC | 1 |
| Mukhopadhyay, S | 1 |
| Das, S | 2 |
| Pal, PP | 1 |
| Basu, SR | 1 |
| Benhamou, D | 2 |
| Wong, C | 1 |
| Leo, S | 1 |
| Sng, BL | 1 |
| Lim, Y | 1 |
| Sia, AT | 1 |
| Yamashita, K | 1 |
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| Ando, Y | 1 |
| Tanabe, T | 1 |
| Terao, Y | 1 |
| Sumikawa, K | 1 |
| Utvoll, J | 1 |
| Beausang-Linder, M | 1 |
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| Malvasi, A | 1 |
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| Stark, M | 1 |
| Pontrelli, G | 1 |
| Brizzi, A | 1 |
| Wetzl, RG | 1 |
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| Apiliogullari, S | 1 |
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| Hirai, H | 1 |
| Toyama, Y | 1 |
| Takahata, O | 1 |
| Iwasaki, H | 1 |
| Kazak Bengisun, Z | 1 |
| Aysu Salviz, E | 1 |
| Darcin, K | 1 |
| Suer, H | 1 |
| Ates, Y | 1 |
| Yousef, AA | 1 |
| Amr, YM | 1 |
| Rukewe, A | 1 |
| Alonge, T | 1 |
| Fatiregun, A | 1 |
| Merivirta, RM | 1 |
| Kuusniemi, KS | 2 |
| Hurme, SA | 1 |
| Neuvonen, PJ | 2 |
| Rautakorpi, PJ | 1 |
| Olkkola, KT | 1 |
| Leino, KA | 2 |
| Candido, KD | 1 |
| Hennes, J | 1 |
| Gonzalez, S | 1 |
| Mikat-Stevens, M | 1 |
| Pinzur, M | 1 |
| Vasic, V | 1 |
| Knezevic, NN | 1 |
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| Pistorio, A | 1 |
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| Montobbio, G | 1 |
| Tuo, P | 1 |
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| Ruksa, A | 1 |
| Carvalho, B | 1 |
| Collins, J | 1 |
| Drover, DR | 1 |
| Atkinson Ralls, L | 1 |
| Riley, ET | 1 |
| Lee, YS | 1 |
| Park, YC | 1 |
| Kim, JH | 1 |
| Kim, WY | 1 |
| Yoon, SZ | 1 |
| Moon, MG | 1 |
| Min, TJ | 1 |
| Milan, Z | 1 |
| Kocarev, M | 1 |
| Rawari, V | 1 |
| Hong, JY | 1 |
| Kim, WO | 1 |
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| Choi, Y | 1 |
| Kil, HK | 1 |
| Düger, C | 1 |
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| Mäkelä, K | 1 |
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| Pitkänen, MT | 1 |
| Rucklidge, MW | 1 |
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| Freeman, K | 1 |
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| Takeda, J | 1 |
| Salman, MA | 1 |
| Yücebaş, ME | 1 |
| Coşkun, F | 1 |
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| Loffredi, M | 1 |
| Wang, WY | 1 |
| Heikkinen, M | 1 |
| Ahonen, R | 1 |
| Booth, JV | 1 |
| Lindsay, DR | 1 |
| Olufolabi, AJ | 1 |
| El-Moalem, HE | 1 |
| Reynolds, JD | 1 |
| Goldstein, A | 1 |
| Grimault, P | 1 |
| Henique, A | 1 |
| Keller, M | 1 |
| Fortin, A | 1 |
| Darai, E | 1 |
| Hills-Wright, P | 1 |
| Potparic, O | 1 |
| Shende, D | 2 |
| Sadhasivam, S | 1 |
| Madan, R | 1 |
| Leung, CC | 1 |
| Chan, YM | 1 |
| Ngai, SW | 1 |
| Ng, KF | 1 |
| Tsui, SL | 1 |
| Sakaguchi, Y | 1 |
| Sakura, S | 1 |
| Shinzawa, M | 1 |
| Saito, Y | 1 |
| Borgeat, A | 1 |
| Kalberer, F | 1 |
| Jacob, H | 1 |
| Ruetsch, YA | 1 |
| Gerber, C | 1 |
| Deb, K | 1 |
| Subramaniam, R | 1 |
| Dehran, M | 1 |
| Tandon, R | 1 |
| Silvasti, M | 1 |
| Pitkänen, M | 1 |
| Butterfield, NN | 1 |
| Schwarz, SK | 1 |
| Ries, CR | 1 |
| Franciosi, LG | 1 |
| Day, B | 1 |
| MacLeod, BA | 1 |
| Gunduz, M | 1 |
| Ozcengiz, D | 1 |
| Ozbek, H | 1 |
| Isik, G | 1 |
| Lee, IO | 1 |
| Kong, MH | 1 |
| Lee, MK | 1 |
| Kim, NS | 1 |
| Choi, YS | 1 |
| Lim, SH | 1 |
| Matsota, P | 1 |
| Livanios, S | 1 |
| Marinopoulou, E | 1 |
| Ng, HP | 1 |
| Cheong, KF | 1 |
| Lim, A | 1 |
| Lim, J | 1 |
| Puhaindran, ME | 1 |
| Hayashi, K | 1 |
| Higuchi, J | 1 |
| Sakio, H | 1 |
| Tanaka, Y | 1 |
| Onoda, N | 1 |
| Vercauteren, M | 1 |
| Vereecken, K | 1 |
| La Malfa, M | 1 |
| Coppejans, H | 1 |
| Adriaensen, H | 1 |
| Suresh, S | 1 |
| Barcelona, SL | 1 |
| Young, NM | 1 |
| Seligman, I | 1 |
| Heffner, CL | 1 |
| Coté, CJ | 1 |
| Køhler, F | 1 |
| Sørensen, JF | 1 |
| Helbo-Hansen, HS | 1 |
| Yazigi, A | 1 |
| Chalhoub, V | 1 |
| Madi-Jebara, S | 1 |
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| Crews, JC | 1 |
| Weller, RS | 1 |
| Moss, J | 1 |
| James, RL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison Between Quadratus Lumborum Block and Epidural on Stress Response and Perioperative Cellular Immunological Function of Laparoscopic Nephrectomy Kidney Donor[NCT03520205] | 62 participants (Actual) | Interventional | 2018-05-01 | Completed | |||
| A Randomized Clinical Trial to Compare the Addition of Epinephrine (no Epinephrine, 100mcg, and 200mcg) to the Standard Dose of Hyperbaric Bupivacaine 12mg, Fentanyl 20mcg and Morphine 150mcg in Scheduled C-sections.[NCT03335293] | Phase 4 | 0 participants (Actual) | Interventional | 2019-10-31 | Withdrawn (stopped due to Due to FDA constraints on the off label use of the medications we will not be able to conduct this evaluation.) | ||
| A Prospective Randomized Controlled Trial Examining the Effectiveness of a Single Shot of Liposomal Bupivicaine for Reducing Post-operative Pain and Narcotic Use in Outpatient Rotator Cuff Surgery[NCT03822182] | Phase 4 | 78 participants (Actual) | Interventional | 2018-10-24 | Completed | ||
| Comparison of Ultrasound-Guided Type-II Pectoral Nerve Block and Rhomboid Intercostal Block for Pain Management Following Mastectomy Surgery[NCT04297007] | 90 participants (Actual) | Interventional | 2020-03-23 | Completed | |||
| Effect of IV Nalbuphine on Postoperative Nausea and Vomiting Following Intrathecal Morphine in Patients Undergoing Inguinal Hernia Repair[NCT05704673] | 80 participants (Anticipated) | Interventional | 2023-06-01 | Not yet recruiting | |||
| Comparison of Rhomboid Intercostal Block and Erector Spina Plan Block for Peri-operative Analgesia in Mastectomy[NCT04259502] | 80 participants (Anticipated) | Interventional | 2020-02-29 | Not yet recruiting | |||
| Comparison of the Analgesic Efficacy of Ultrasound-guided Paravertebral Block and Mid-point Transverse Process Pleura Block in Mastectomy Surgery[NCT05332028] | Phase 4 | 64 participants (Actual) | Interventional | 2020-03-26 | Completed | ||
| Ultrasound Guided Erector Spinae Block Versus Thoracic Paravertebral Block for Postoperative Pain Control After Open Nephrectomy : A Randomized Controlled Trial[NCT04719507] | 45 participants (Anticipated) | Interventional | 2021-01-31 | Not yet recruiting | |||
| Comparison of Erector Spinae Plane Block With Thoracic Paravertebral Block for Breast Surgery[NCT03480958] | 75 participants (Actual) | Interventional | 2018-03-28 | Completed | |||
| Comparison of Programmed Intermittent Bolus Infusions of Spinae Plane Block Versus Paravertebral Block for Analgesia in Minimally Invasive Direct Coronary Artery Bypass Grafting[NCT05320718] | 140 participants (Anticipated) | Interventional | 2022-04-15 | Recruiting | |||
| Erector Spinae Plane Block in Different Volumes on Postoperative Pain Control Following Breast Surgery: A Randomized, Prospective Study[NCT05232084] | 40 participants (Actual) | Interventional | 2022-01-27 | Completed | |||
| Ultrasound-Guided Versus Conventional Injection for Caudal Block in Children[NCT03337191] | 134 participants (Actual) | Interventional | 2016-01-01 | Completed | |||
| Laparoscopic vs Ultrasound-Guided Transversus Abdominis Plane Block in Minimally Invasive Colon Surgery: A Randomized Controlled Multicentre Clinical Trial[NCT04311099] | Phase 4 | 360 participants (Anticipated) | Interventional | 2021-01-14 | Recruiting | ||
| Laparoscopic Guided vs Ultrasound Guided Transabdominal Plane Block in Minimal Invasive Colorectal Surgery; a Comparison Between Time of Procedure and Efficacy on Pain Relief and Postoperative Opioid Consumption.[NCT04907461] | 170 participants (Anticipated) | Interventional | 2021-05-31 | Recruiting | |||
| The Effect of Ultrasound-Guided Erector Spinae Block on Respiratory Function After Laparoscopic Cholecystectomy[NCT03815799] | 68 participants (Actual) | Interventional | 2019-03-03 | Completed | |||
| Postoperative Efficacy of Subcostal TAP Block in Laparoscopic Sleeve Gastrectomy Surgery: a Randomized Controlled Trial[NCT06156657] | 100 participants (Anticipated) | Interventional | 2023-01-30 | Recruiting | |||
| Evaluation of Postoperative Analgesic Effect of Ultrasound Guided Erector Spinae Plane Block and Subcostal Transverse Abdominis Plane Block in Laparoscopic Cholecystectomy, Randomised Controlled Study[NCT04116008] | 70 participants (Actual) | Interventional | 2019-11-10 | Completed | |||
| Evaluation of Postoperative Analgesic Effect of Ultrasound Guided Erector Spinae Plane Block and Oblique Subcostal Transverse Abdominis Plane Block in Laparoscopic Cholecystectomy, Randomised Controlled Study[NCT03508531] | 60 participants (Actual) | Interventional | 2018-03-23 | Completed | |||
| A Randomized Controlled Trial to Compare Pain Medications in Children Undergoing Strabismus Surgery[NCT02789969] | 128 participants (Anticipated) | Interventional | 2016-04-30 | Recruiting | |||
| Comparison of Peritonsillar Dexamethasone-bupivacaine and Bupivacaine Infiltration for Tonsillectomy Pain Relief in Children:a Randomized,Double Blind,Controlled Study.[NCT03443778] | Phase 4 | 120 participants (Anticipated) | Interventional | 2017-12-15 | Active, not recruiting | ||
| Liposomal Bupivacaine Versus Bupivacaine for Postoperative Analgesia Following Video-assisted Thoracoscopic Surgery.[NCT03036085] | Phase 2/Phase 3 | 200 participants (Anticipated) | Interventional | 2017-02-28 | Not yet recruiting | ||
| Impact of Counseling and Education on Opioid Consumption After Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial[NCT04885231] | 80 participants (Anticipated) | Interventional | 2021-05-12 | Active, not recruiting | |||
| Postoperative Analgesia After Cardiac Surgery - A Double-Blind, Prospective and Randomized Comparison of Wound Infiltration With Liposomal Bupivacaine and Bupivacaine Hydrochloride[NCT03270514] | Phase 3 | 60 participants (Actual) | Interventional | 2018-11-15 | Completed | ||
| Effect of Transversus Abdominis Plane Block With Bupivacaine on Anti-inflammatory Response in Living Liver Donors[NCT04232904] | Phase 4 | 70 participants (Anticipated) | Interventional | 2019-12-02 | Recruiting | ||
| A Comparison of Tumescence in Breast Reduction Surgery[NCT01602692] | Phase 4 | 40 participants (Actual) | Interventional | 2012-08-31 | Completed | ||
| The Use of Liposomal Bupivacaine for Pain Control Following Mastectomy and Breast Reconstruction[NCT03722927] | Phase 4 | 3 participants (Actual) | Interventional | 2018-06-14 | Completed | ||
| Effect of Thoracic Epidural Analgesia for Thoracic Surgery on Arrhythiogenesis[NCT01718717] | 50 participants (Anticipated) | Interventional | 2014-12-31 | Not yet recruiting | |||
| Effect of Low-dose Epidural Morphine Combined With Single-injection Femoral Nerve Block on Postoperative Analgesia in Patients After Total Knee Arthroplasty[NCT03203967] | 110 participants (Actual) | Interventional | 2017-07-01 | Completed | |||
| A Analgesic Study of Adductor Canal &IPACK Block With Liposomal Bupivacaine in Knee Arthroplasty ：A Randomized，Double-controlled，Parallel-controlled，Single-center Study[NCT06145165] | Phase 1 | 90 participants (Anticipated) | Interventional | 2023-12-01 | Recruiting | ||
| The Effects of Infraorbital Nerve Block With Dexmedetomidine Added to Bupivacaine on Fentanyl Requirement During Endoscopic Transsphenoidal Approach to Remove Pituitary Tumor: Prospective Randomized Double Blinded Control Study[NCT04785222] | Phase 4 | 63 participants (Anticipated) | Interventional | 2021-07-31 | Not yet recruiting | ||
| Comparison of Periosteal and Subcutaneous Infusions of Articaine and Bupivacaine in Treatment of Acute Pain After Sternotomy[NCT01536717] | Phase 4 | 36 participants (Actual) | Interventional | 2012-03-31 | Suspended | ||
| How Low Can we go: A Double-blinded Randomized Controlled Trial to Compare Bupivacaine 5 mg and Bupivacaine 7.5 mg for Spinal Anesthesia in Cesarian Delivery in Indonesian Population[NCT03834454] | 112 participants (Actual) | Interventional | 2013-10-01 | Completed | |||
| Risk-benefit Analysis of Intrathecal Morphine Administration to Patients Undergoing Surgical Treatment of Proximal Femoral Fracture (Monocentric, Single-blinded, Randomized Clinical Study Compared to Standard Treatment)[NCT05920642] | Phase 4 | 50 participants (Anticipated) | Interventional | 2023-09-04 | Not yet recruiting | ||
| Is the Application of Scopolamine Patch With or Without Intra-operative Acupressure Point P6 Stimulation More Effective Than Intra-operative Acupressure Point P6 Stimulation Alone?[NCT02960113] | Phase 4 | 240 participants (Actual) | Interventional | 2016-05-31 | Completed | ||
| Fentanyl Versus Midazolam as an Adjunct to Intrathecal Bupivacaine for Postoperative Analgesia in Children Undergoing Infraumbilical Surgery[NCT03592537] | Phase 2/Phase 3 | 90 participants (Actual) | Interventional | 2018-08-15 | Completed | ||
| A Randomized Controlled Trial Comparing the Adductor Canal Catheter (ACC) and Intra-articular Catheter (IAC) Following Primary Total Knee Arthroplasty[NCT02497911] | Phase 4 | 110 participants (Anticipated) | Interventional | 2014-01-31 | Enrolling by invitation | ||
| Analgesic Efficacy of Adductor Canal Block (ACB) Before and After Primary Total Knee Arthroplasty (TKA): A Prospective Randomized Trial to Compare Postoperative Clinical Outcomes[NCT02908711] | Phase 4 | 50 participants (Actual) | Interventional | 2016-10-31 | Completed | ||
| A Double-Blinded Randomized Controlled Trial Comparing the Adductor Canal Catheter (ACC) and Local Infiltration of Analgesia (LIA) Following Primary Total Knee Arthroplasty[NCT02603900] | Phase 4 | 0 participants (Actual) | Interventional | 2015-10-31 | Withdrawn | ||
| Continuous Femoral Nerve Block Versus Local-wound Infiltration Analgesia For Patients Receiving Unilateral Total Knee Arthroplasty --- A Randomized Controlled Trial[NCT02284620] | Phase 4 | 320 participants (Anticipated) | Interventional | 2015-01-31 | Recruiting | ||
| Analgesic Efficacy of Quadaratus Lumborum Block (QLB) for Laparoscopic Colectomy Surgery: A Prospective Observational Case Control Trial to Evaluate Clinical Outcomes[NCT03017638] | 14 participants (Actual) | Observational | 2017-02-27 | Completed | |||
| A Prospective Triple-masked Randomized Controlled Trial Measuring Analgesia Duration of Dexamethasone, Buprenorphine, or Clonidine With Ropivacaine for Interscalene Nerve Block[NCT03117140] | Phase 4 | 160 participants (Actual) | Interventional | 2013-12-31 | Completed | ||
| Effectiveness of Subarachnoid Hyperbaric Bupivacaine on Mean Arterial Blood Pressure in Pregnant Patients With Obesity Operated by Cesarean Section[NCT04205344] | Phase 4 | 40 participants (Actual) | Interventional | 2017-02-01 | Completed | ||
| Effect of Subarachnoid Hyperbaric Bupivacaine on Mean Arterial Pressure in Obese Pregnant Patients Undergoing Cesarean Section[NCT06060015] | Phase 4 | 106 participants (Anticipated) | Interventional | 2023-08-01 | Recruiting | ||
| Intrathecal Hydromorphone for Post-cesarean Delivery Pain - a Dose Finding Study[NCT01943565] | Phase 4 | 29 participants (Actual) | Interventional | 2014-12-31 | Terminated (stopped due to Research question answered by another group of researchers (Sviggum et al)) | ||
| [NCT01172782] | 60 participants (Actual) | Interventional | 2009-07-31 | Completed | |||
| Does Single Dose Dexmedetomidine for Procedural Sedation Reduce Post-operative Pain in Total Knee Arthroplasty? A Randomized Control Study[NCT02466022] | Phase 3 | 54 participants (Actual) | Interventional | 2015-06-30 | Completed | ||
| The Effects of Intravenous Dexmedetomidine on Spinal Anesthesia Using Low Dose Diluted Bupivacaine for Transurethral Resection of Prostate[NCT01224470] | 51 participants (Actual) | Interventional | 2010-11-30 | Completed | |||
| Comparison of Caudal Bupivacaine Alone With Bupivacaine Plus Two Doses of Dexmedetomidine for Postoperative Analgesia in Pediatric Patients Undergoing Infra-umbilical Surgery: A Randomized Controlled Double Blinded Study[NCT02385435] | Phase 2/Phase 3 | 91 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
| Effects Of Adjuvants (Dexamethasone and Dexmedetomidine) to Caudal Anesthesia on Cardiac Output and Hemodynamics Measured By Electrical Cardiometry In Children: A Randomized Double Blind Study[NCT03101137] | Phase 4 | 48 participants (Actual) | Interventional | 2016-02-29 | Completed | ||
| Efficacy of a Single-shot Wound Infiltration With Bupivacaine/Adrenalin During Cesarean Section in Reducing Postoperative Pain. A Randomized Prospective Controlled Trial[NCT03395912] | 288 participants (Actual) | Interventional | 2018-01-25 | Completed | |||
| Levobupivacïne Into Post-analgesia : Randomized Monocentric Study Against Placebo[NCT00621907] | Phase 3 | 140 participants (Actual) | Interventional | 2008-03-31 | Completed | ||
| The Effect of Pre-operative Transversus Abdominis Plane (TAP) Block in the Quality of Recovery of Patients Undergoing Laparoscopic Hysterectomy: a Prospective, Randomized, Blinded Study[NCT01074229] | 75 participants (Actual) | Interventional | 2010-03-31 | Completed | |||
| The Effect of Pre Operative Transversus Abdominis Plane (TAP) Block in the Quality of Recovery of Patients Undergoing Outpatient Laparoscopic Gynecological Surgery: A Prospective, Randomized Blinded Study[NCT01075074] | 75 participants (Actual) | Interventional | 2010-08-31 | Completed | |||
| A Randomized Controlled Clinical Trial of Intrathecal Chloroprocaine vs. Bupivacaine for Cervical Cerclage[NCT03305575] | Phase 4 | 10 participants (Actual) | Interventional | 2017-10-13 | Completed | ||
| Does a Single Intravenous Dose of Ketamine Reduce the Need for Supplemental Opioids in Post-Cesarean Section Patients?[NCT00486902] | 188 participants (Actual) | Interventional | 2006-07-31 | Completed | |||
| Randomised and Double-blind Clinical Trial on Post-operative Analgesic Efficacy in Colorectal Surgery and Hepatic Surgery With Continuous Infusion of Local Anesthesia vs Saline Serum in the Surgical Incision.[NCT01075646] | Phase 4 | 225 participants (Actual) | Interventional | 2009-03-31 | Completed | ||
| Postoperative Narcotic Use After Laparoscopic Gynecologic Surgery: A Randomized, Double-blind, Placebo-controlled Trial Comparing Continuous Intraperitoneal Infusion of Ropivacaine Versus Saline for Post-operative Pain Control[NCT04118777] | 0 participants (Actual) | Interventional | 2020-05-01 | Withdrawn (stopped due to Misregistered to wrong sponsor.) | |||
| Efficacy of Thoracic Paravertebral Block vs Local Anesthesia of the Surgical Wound in Reduction of Acute Post-surgical Pain in Patients With Breast Cancer. Controlled Phase III, Randomized, Single-blind, Superiority Clinical Trial.[NCT02609321] | Phase 3 | 60 participants (Actual) | Interventional | 2015-11-30 | Completed | ||
| Description of the Analgesia Obtained With the Anesthesiological Protocols Currently Used in Breast Surgery[NCT04309929] | 200 participants (Actual) | Observational | 2016-09-12 | Completed | |||
| Evaluating the Use of Enhanced Recovery Strategies and Paravertebral Block in Elective Breast Reduction and Breast Augmentation[NCT03187080] | Phase 4 | 296 participants (Anticipated) | Interventional | 2024-01-31 | Suspended (stopped due to per Research Hold) | ||
| A Randomized, Subject-Masked, Active-Controlled, Parallel-Arm Clinical Trial Comparing Erector Spinae and Paravertebral Nerve Blocks[NCT03549234] | Phase 4 | 100 participants (Actual) | Interventional | 2018-07-12 | Completed | ||
| The Use of Very Low Dose Caudal Morphine for Postoperative Pain Management in Out Patients[NCT00938821] | 33 participants (Actual) | Observational | 2010-01-31 | Completed | |||
| Efficacy of Prevention for Postoperative Nausea and Vomiting After Intrathecal Morphine in Cesarean Section: a Randomized Comparison of Metoclopramide or Ondansetron Alone or in the Combination With Dexamethasone.[NCT00892996] | 120 participants (Actual) | Interventional | 2009-05-31 | Active, not recruiting | |||
| Role of Dexamethasone or Ondansetron in the Quality of Recovery After Intrathecal Morphine Administration in Patients Undergoing Lower Limb Surgery.[NCT03035942] | Phase 4 | 135 participants (Actual) | Interventional | 2017-01-02 | Completed | ||
| Spinal Hydromorphone Versus Morphine for Post-Cesarean Delivery Analgesia: A Non-Inferiority Trial[NCT03592992] | Phase 4 | 126 participants (Actual) | Interventional | 2020-11-11 | Completed | ||
| Fentanyl Versus Morphine in Spinal Anesthesia for Caesarian Section - Study on Perioperative Analgesia, Side Effects and Patient 's Satisfaction[NCT05533229] | 160 participants (Actual) | Observational | 2022-04-01 | Completed | |||
| Decreased Neuraxial Morphine and Adjunctive Peripheral Nerve Blockade to Reduce Severity of Side Effects and Opioid Use After Cesarean Delivery[NCT04279054] | Early Phase 1 | 87 participants (Actual) | Interventional | 2020-09-09 | Active, not recruiting | ||
| Investigation of Pharmacokinetics and Pharmacodynamics of Epidural Methadone in Healthy Volunteers[NCT03525509] | Early Phase 1 | 13 participants (Actual) | Interventional | 2018-06-04 | Completed | ||
| Ultrasound Guided (USG) PECS Versus Local Infiltration Anaesthesia (LIA) for Breast Cancer Surgery - A Randomized Quadruple Blinded Efficacy and Safety Study[NCT03555227] | 110 participants (Actual) | Interventional | 2017-09-25 | Completed | |||
| A Comparison of Ultrasound-assisted Paravertebral Block and General Anesthesia for Outpatient Breast Cancer Surgery, a Prospective Randomized Trial[NCT00645138] | Phase 3 | 40 participants (Anticipated) | Interventional | 2008-04-30 | Completed | ||
| Comparison Of Ultrasound-Assisted Paravertebral Block And Traditional Paravertebral Block For Pain Control After Thoracic Surgery, A Prospective Randomized Trial[NCT01949480] | 45 participants (Actual) | Interventional | 2013-07-01 | Completed | |||
| Infiltration of Bupivacaine Local Anesthetic to Trocar Insertion Sites After Laparoscopic Hysterectomy: A Randomized, Double-Blind, Placebo-Controlled Trial[NCT01688596] | Phase 1 | 135 participants (Actual) | Interventional | 2012-09-30 | Completed | ||
| TAP) Block in Morbid Obese Patients Undergoing Laparoscopic Gastric Bypass Surgery: A Prospective,Randomized, Blinded Study[NCT01075087] | 19 participants (Actual) | Interventional | 2010-03-31 | Completed | |||
| The Effect of Systemic Intraoperative Lidocaine on Postoperative Pain and Quality of Recovery on Morbid Obese Patients Undergoing Laparoscopic Gastric Bypass Surgery[NCT01180660] | 51 participants (Actual) | Interventional | 2010-06-30 | Completed | |||
| Impact of Intraperitonael Nebulization of Local Anesthetic on Postoperative Pain Associated With Laparoscopic Surgery[NCT01512914] | Phase 3 | 120 participants (Actual) | Interventional | 2008-05-31 | Completed | ||
| Effect of Preemptive Ibuprofen and Dexketoprofen on Postoperative Opioid Consumption in Patients Undergoing Laparoscopic Cholecystectomy[NCT03607266] | 90 participants (Anticipated) | Observational | 2018-08-20 | Recruiting | |||
| Intraperitoneal Local Anesthetic in Bariatric Surgery: A Double Blind-randomized Controlled Pilot Trial[NCT03175081] | 54 participants (Actual) | Interventional | 2017-04-27 | Completed | |||
| The Effect of Intravenous Infusion of Tramadol-ondansetron on Recovery After Caesarean Section. A Prospective, Observational and Non-inferiority Study Against Epidural Analgesia.[NCT05879536] | 312 participants (Anticipated) | Observational | 2023-05-23 | Recruiting | |||
| Great Auricular Nerve Block for Children Undergoing Tympanomastoid Surgery: Does the Addition of Clonidine Increase the Duration of Postoperative Analgesia?[NCT01638052] | Phase 2 | 56 participants (Actual) | Interventional | 2006-02-28 | Completed | ||
| IRB-HSR# 14583: Intravenous Ondansetron to Attenuate the Hypotensive, Bradycardic Response to Spinal Anesthesia in Healthy Parturients[NCT01414777] | Phase 2/Phase 3 | 68 participants (Actual) | Interventional | 2009-11-30 | Completed | ||
| A Randomized Two-parallel Group Controlled Trial Comparing the Effects of 20mg Parecoxib as an Adjunct to 0.75% Ropivacaine in Ultrasound-guided Supraclavicular Block for Upper Limb Surgery[NCT03480165] | Phase 3 | 86 participants (Actual) | Interventional | 2016-06-20 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Patient-reported post-operative opioid use (converted to morphine equivalents), collected post operatively, in 8-hour increments, for a total of 96 hours post-surgery Patients will be prompted via text message to provide the amount of narcotics (number of pills converted to morphine equivalents) taken over the course of the previous 8 hours. If a response text message is not received, a phone call will be made to obtain the information. Patients who do not have a smart phone will receive a phone call or keep a personal log of narcotic use. (NCT03822182)
Timeframe: 4 days post procedure
| Intervention | morphine milligram equivalents (Mean) | |||
|---|---|---|---|---|
| POD 1 MME | POD 2 MME | POD 3 MME | POD 4 MME | |
| Control/Bupivicaine+DMSO | 26.5 | 36.1 | 29.7 | 21.1 |
| Liposomal Bupivicaine | 22.8 | 21.9 | 17.8 | 18.1 |
| Liposomal Bupivicaine + DMSO | 18.8 | 22.8 | 14.4 | 16.8 |
Patient-reported post-operative VAS pain (on a scale of 0-10 with zero implying no pain and 10 indicating severe pain), measured post operatively, in 8-hour increments, for a total of 96 hours post-surgery, Patients will be prompted via text message to provide VAS pain every 8 hours. If a response text message is not received, a phone call will be made to obtain the information. Patients who do not have a smart phone will receive a phone call or keep a personal log of VAS pain. (NCT03822182)
Timeframe: 4 days post procedure
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| Postoperative day 1 VAS | Postoperative day 2 VAS | Postoperative day 3 VAS | Postoperative day 4 VAS | |
| Control/Bupivicaine+DMSO | 3.1 | 3.3 | 2.4 | 1.9 |
| Liposomal Bupivicaine | 3.5 | 2.8 | 3.2 | 2.9 |
| Liposomal Bupivicaine + DMSO | 2.4 | 2.8 | 2.1 | 2.3 |
Readmission to hospital will be noted (NCT03270514)
Timeframe: From end of surgery assessed up to 30 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Exparel Injectable Product | 3 |
| Bupivacaine Hydrochloride | 3 |
Mortality will be noted at specific timepoints (NCT03270514)
Timeframe: From end of surgery assessed up to 30 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Exparel Injectable Product | 0 |
| Bupivacaine Hydrochloride | 1 |
Episodes of NIV such as upper airway masks or similar devices will be quantified (NCT03270514)
Timeframe: From time of end of surgery to 72 hours post-operatively or until hospital discharge
| Intervention | Participants (Count of Participants) |
|---|---|
| Exparel Injectable Product | 6 |
| Bupivacaine Hydrochloride | 5 |
Patient will give an assessment regarding pain management on a scale of 0 - 10 with 0 indicating the lowest satisfaction with pain management and 10 indicating the highest satisfaction with pain management (NCT03270514)
Timeframe: Given at the time of discharge up to 30 days post-operatively
| Intervention | score on a scale (Median) |
|---|---|
| Exparel Injectable Product | 10 |
| Bupivacaine Hydrochloride | 10 |
The time it takes until patient ambulates will be measured (NCT03270514)
Timeframe: From time of end of surgery to time of mobilization up to 72 hours or discharge, *assessed up to 120 hours*
| Intervention | hours (Median) |
|---|---|
| Exparel Injectable Product | 42 |
| Bupivacaine Hydrochloride | 45 |
The time it takes until the patient is able to/medically cleared to consume food or liquid will be measured (NCT03270514)
Timeframe: From time of end of surgery to time of oral intake up to 72 hours post-operatively or until hospital discharge
| Intervention | hours (Median) |
|---|---|
| Exparel Injectable Product | 7 |
| Bupivacaine Hydrochloride | 5.6 |
The time it takes until the patient advances from bedrest to out of bed (OOB) to chair will be measured (NCT03270514)
Timeframe: From time of end of surgery to time of mobilization up to 72 hours post-operatively
| Intervention | hours (Median) |
|---|---|
| Exparel Injectable Product | 16 |
| Bupivacaine Hydrochloride | 16 |
Whether a patient experiences at least one episode of nausea and emesis will be measured (NCT03270514)
Timeframe: From time of end of surgery to 72 hours post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Exparel Injectable Product | 3 |
| Bupivacaine Hydrochloride | 9 |
Instances of re-intubation will be recorded (NCT03270514)
Timeframe: From time of end of surgery to patient discharge up to one week
| Intervention | Participants (Count of Participants) |
|---|---|
| Exparel Injectable Product | 3 |
| Bupivacaine Hydrochloride | 3 |
The time it takes until the patient is extubated post-operatively will be measured (NCT03270514)
Timeframe: From the end of surgery until the patient is extubated up to 72 hours post-operatively
| Intervention | hours (Median) |
|---|---|
| Exparel Injectable Product | 3.85 |
| Bupivacaine Hydrochloride | 3.47 |
Frequency of incentive spirometry will be measured (NCT03270514)
Timeframe: From time of end of surgery to 72 hours post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Exparel Injectable Product | 29 |
| Bupivacaine Hydrochloride | 31 |
Length of both hospital and ICU stay will be measured (NCT03270514)
Timeframe: From date of surgery assessed up to 30 day post-operatively
| Intervention | days (Median) | |
|---|---|---|
| Length of ICU stay | Length of postoperative hospital stay | |
| Bupivacaine Hydrochloride | 1.71 | 6 |
| Exparel Injectable Product | 1.51 | 7 |
Postoperative pain scores evaluated by numeric rating scale or (NRS) where 0- no pain and 10- worst pain, at rest and at movement (NCT03270514)
Timeframe: NRS scores will be evaluated every 4 hours until 24 hours post-operatively, every 8 hours until 48 hours post-operatively, and every 12 hours for 72 hours post-operatively
| Intervention | score on a scale (Mean) | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4hrs. at rest | 4hrs. with movement | 8hrs. at rest | 8hrs. with movement | 12hrs. at rest | 12hrs. with movement | 16hrs. at rest | 16hrs. with movement | 20hrs. at rest | 20hrs. with movement | 24hrs. at rest | 24hrs. with movement | 32hrs. at rest | 32hrs. with movement | 40hrs. at rest | 40hrs. with movement | 48hrs. at rest | 48hrs. with movement | 60hrs. at rest | 60hrs. with movement | 72hrs. at rest | 72hrs. with movement | |
| Bupivacaine Hydrochloride | 5.03 | 6.64 | 4.996 | 6.6 | 4.962 | 6.56 | 4.928 | 6.52 | 4.894 | 6.48 | 4.86 | 6.44 | 4.792 | 6.32 | 4.724 | 6.24 | 4.656 | 6.16 | 4.554 | 6.04 | 4.452 | 5.92 |
| Exparel Injectable Product | 4.7482 | 5.75 | 4.7262 | 5.74 | 4.7042 | 5.73 | 4.6822 | 5.72 | 4.6602 | 5.71 | 4.6382 | 5.7 | 4.5942 | 5.68 | 4.5282 | 5.66 | 4.4622 | 5.64 | 4.3742 | 5.61 | 4.2862 | 5.58 |
Stress response suppression as a result of treatment will be evaluated by comparing hormone levels between the groups. Serum cortisol levels will be taken to measure this. (NCT03270514)
Timeframe: Measured 8, 48, and 72 hours post-operatively
| Intervention | µg/dL (Median) | ||
|---|---|---|---|
| 8 hours postoperatively | 48 hours postoperatively | 72 hours postoperatively | |
| Bupivacaine Hydrochloride | 36.5 | 19 | 17 |
| Exparel Injectable Product | 30 | 15 | 16 |
All narcotics administered in the first 0-8, 8-24, 24-48, and 48-72 hours and the total narcotics administered in the 0-72 hours postoperative period(PCA narcotics, nurse-administered IV narcotics, and oral narcotics). All narcotics will be converted to total IV morphine equivalent for comparison between two groups. (NCT03270514)
Timeframe: 0-72 hours post-operative period
| Intervention | oral morphine equivalents in mg (Median) | ||||
|---|---|---|---|---|---|
| 0-8 hours | 8-24 hours | 24-48 hours | 48-72 hours | 0-72 hours | |
| Bupivacaine Hydrochloride | 10 | 34.5 | 45 | 26.5 | 105 |
| Exparel Injectable Product | 15 | 45 | 45 | 15 | 139 |
The secondary outcomes that will be measured in this study include the amount of anti-emetic medication used in the first 24 hours post-op. This data will be attained by reviewing the medical record and through the validated survey questions. (NCT01602692)
Timeframe: Up to 24 hours following surgery
| Intervention | micrograms (Mean) |
|---|---|
| Tumescent Solution With Dilute Epinephrine | 131.30 |
| Tumescent Solution With Dilute Lidocaine and Epinephrine | 120.00 |
The patient's medical record will be reviewed to determine the time it took for the patient to be transitioned from the PACU (post anesthesia care unit) till discharge. This includes the time spent in the PACU, time spent in phase 2 and the total time to discharge. (NCT01602692)
Timeframe: Up to 24 hours following surgery
| Intervention | minutes (Mean) |
|---|---|
| Tumescent Solution With Dilute Epinephrine | 158 |
| Tumescent Solution With Dilute Lidocaine and Epinephrine | 153 |
The patient's medical record will be reviewed to see if the patient was readmitted to the hospital (unplanned) due to complications related to this surgery. (NCT01602692)
Timeframe: Up to 1 week following surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Tumescent Solution With Dilute Epinephrine | 0 |
| Tumescent Solution With Dilute Lidocaine and Epinephrine | 0 |
Aim 1 is to determine the effect of dilute lidocaine in tumescent solution on post-operative pain following breast reduction surgery. The amount of narcotic medication administered (in Postanesthesia Care Unit (PACU), phase 2 and up to 24 hours post-op) determined by reviewing the medical record. (NCT01602692)
Timeframe: Up to 24 hours following surgery
| Intervention | mg (Mean) | |
|---|---|---|
| PACU IV hydromorphone | First 24 hr Post-op oxycodone | |
| Tumescent Solution With Dilute Epinephrine | 0.89 | 32.19 |
| Tumescent Solution With Dilute Lidocaine and Epinephrine | 0.55 | 29.47 |
The secondary outcomes that will be measured in this study include the amount of anti-emetic medication used in the first 24 hours post-op. This data will be attained by reviewing the medical record and through the validated survey questions. (NCT01602692)
Timeframe: Up to 24 hours following surgery
| Intervention | mg (Mean) | ||||
|---|---|---|---|---|---|
| Mean Intraoperative hydromorphone | Mean Intraoperative midazolam | Mean Intraoperative ketorolac | Mean Intraoperative dexamethasone | Mean Intraoperative ondansetron | |
| Tumescent Solution With Dilute Epinephrine | 0.98 | 2.00 | 11.25 | 6.40 | 3.60 |
| Tumescent Solution With Dilute Lidocaine and Epinephrine | 1.06 | 1.90 | 16.50 | 6.00 | 4.05 |
The secondary outcomes that will be measured in this study include number of episodes of post-operative nausea (subjective feeling vs. emesis). This data will be attained by reviewing the medical record and through the validated survey questions. (NCT01602692)
Timeframe: Up to 24 hours following surgery
| Intervention | episodes (Number) | |
|---|---|---|
| Nausea | Vomiting | |
| Tumescent Solution With Dilute Epinephrine | 8 | 2 |
| Tumescent Solution With Dilute Lidocaine and Epinephrine | 10 | 4 |
Aim 1 is to determine the effect of dilute lidocaine in tumescent solution on post-operative pain following breast reduction surgery. The data points that will be statistically compared will be pain scores determined via a validated pain survey (pain levels on a scale of 0-10 where 10 is the worst pain) and the amount of narcotic medication administered (in Postanesthesia Care Unit (PACU), phase 2 and up to 24 hours post-op) determined from responses to survey questions and by reviewing the medical record. (NCT01602692)
Timeframe: Up to 24 hours following surgery
| Intervention | score on a scale (Mean) | |||
|---|---|---|---|---|
| End of PACU Mean Pain Level | First 24 hrs Post-op Mean Current Pain | First 24 hrs Post-op Mean Worst Pain | First 24 hrs Post-op Mean Least Pain | |
| Tumescent Solution With Dilute Epinephrine | 5.47 | 4.00 | 6.44 | 2.00 |
| Tumescent Solution With Dilute Lidocaine and Epinephrine | 4.47 | 4.28 | 6.68 | 2.53 |
Frequency of postoperative opioid related adverse effects within the first week of surgery will be recorded. This includes nausea, vomiting, pruritus, allergy, respiratory depression. (NCT03722927)
Timeframe: Postoperatively, 1 week
| Intervention | Participants (Count of Participants) |
|---|---|
| Bupivacaine Group | 0 |
| Liposomal Bupivacaine Group | 0 |
The length of stay for hospitalization after mastectomy and breast reconstruction will be recorded. (NCT03722927)
Timeframe: up to 47 Hours
| Intervention | days (Mean) |
|---|---|
| Bupivacaine Group | 1 |
| Liposomal Bupivacaine Group | 1 |
This will be measured by the number of doses within the first month postoperatively and recorded on pain medication daily diary kept by subject. (NCT03722927)
Timeframe: 1 Month
| Intervention | Number of morphine doses (Number) |
|---|---|
| Bupivacaine Group | 0 |
| Liposomal Bupivacaine Group | 20 |
Readmission rates to the hospital within 2 months after mastectomy and breast reconstruction will be recorded (NCT03722927)
Timeframe: Month 2
| Intervention | Participants (Count of Participants) |
|---|---|
| Bupivacaine Group | 0 |
| Liposomal Bupivacaine Group | 0 |
This will be measured every 12 hours for the first 48 hours postoperatively by the level of breast pain associated with arm movements while eating on a scale of 0-10 with higher scores denoting worse outcomes. (NCT03722927)
Timeframe: 48 hours
| Intervention | score on a scale (Mean) |
|---|---|
| 12 hours | |
| Bupivacaine Group | 4 |
This will be measured every 12 hours for the first 48 hours postoperatively by the level of breast pain associated with arm movements while eating on a scale of 0-10 with higher scores denoting worse outcomes. (NCT03722927)
Timeframe: 48 hours
| Intervention | score on a scale (Mean) | |||
|---|---|---|---|---|
| 12 hours | 24 hours | 36 hours | 48 hours | |
| Liposomal Bupivacaine Group | 3.5 | 4 | 3.5 | 2 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) after eversion of the uterus. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: After eversion of the uterus until replacement of the uterus
| Intervention | units on a scale (Mean) |
|---|---|
| Scopolamine Patch | 1.28 |
| Acupressure Point P6 | 1.09 |
| Scopolamine Patch + Acupressure Point P6 | 1.40 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) after replacement of the uterus. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: After replacement of the uterus and to the next 15 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Scopolamine Patch | 2.19 |
| Acupressure Point P6 | 2.19 |
| Scopolamine Patch + Acupressure Point P6 | 2.51 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) after the administration of the regional anesthesia medications. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: From administration of anaesthesia until eversion of uterus
| Intervention | units on a scale (Mean) |
|---|---|
| Scopolamine Patch | 2.71 |
| Acupressure Point P6 | 2.57 |
| Scopolamine Patch + Acupressure Point P6 | 2.84 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) upon arrival to the post-operative recovery room. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: 15 minutes after replacement of the uterus to arrival at post-anaesthesia care unit
| Intervention | units on a scale (Mean) |
|---|---|
| Scopolamine Patch | 0.18 |
| Acupressure Point P6 | 0.25 |
| Scopolamine Patch + Acupressure Point P6 | 0.23 |
The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea at any point during the surgical procedure in each group. (NCT02960113)
Timeframe: Throughout the entire surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Scopolamine Patch | 40 |
| Acupressure Point P6 | 39 |
| Scopolamine Patch + Acupressure Point P6 | 46 |
The investigators will perform objective assessments of whether or not the patients have vomited during the procedure. The investigators will then analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: Throughout the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Scopolamine Patch | 24 |
| Acupressure Point P6 | 25 |
| Scopolamine Patch + Acupressure Point P6 | 31 |
Objective assessments of whether or not the patients have vomited at this point in the surgical procedure will be done. The investigators will analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: After eversion of to replacement of the uterus
| Intervention | Participants (Count of Participants) |
|---|---|
| Scopolamine Patch | 8 |
| Acupressure Point P6 | 6 |
| Scopolamine Patch + Acupressure Point P6 | 9 |
Objective assessments of whether or not the patients have vomited at this point in the surgical procedure will be done. The investigators will analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: After replacement of the uterus and for next 15 minutes
| Intervention | Participants (Count of Participants) |
|---|---|
| Scopolamine Patch | 10 |
| Acupressure Point P6 | 15 |
| Scopolamine Patch + Acupressure Point P6 | 12 |
Objective assessments of whether or not the patients have vomited at this point in the surgical procedure will be done. The investigators will analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: After the administration of the regional anesthesia medications until eversion of the uterus
| Intervention | Participants (Count of Participants) |
|---|---|
| Scopolamine Patch | 20 |
| Acupressure Point P6 | 15 |
| Scopolamine Patch + Acupressure Point P6 | 20 |
Objective assessments of whether or not the patients have vomited at this point in the surgical procedure will be done. The investigators will analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: From 15 minutes after replacement of the uterus until arrival at the post-anaesthesia care unit
| Intervention | Participants (Count of Participants) |
|---|---|
| Scopolamine Patch | 1 |
| Acupressure Point P6 | 1 |
| Scopolamine Patch + Acupressure Point P6 | 4 |
Patients are asked their nausea and vomiting treatment satisfaction (0 = Not Satisfied, 10 = Extremely Satisfied). Patients are also asked their overall satisfaction with the procedure (0 = Not Satisfied, 10 = Extremely Satisfied). (NCT02960113)
Timeframe: Throughout the surgical procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Scopolamine Patch | 9.29 |
| Acupressure Point P6 | 8.96 |
| Scopolamine Patch + Acupressure Point P6 | 9.59 |
Patients are assessed from needle removal to when they are no longer able to feel cold on the blocked extremity (NCT03117140)
Timeframe: Day one
| Intervention | minutes (Median) |
|---|---|
| Plain Ropivacaine | 6 |
| Ropivacaine + Buprenorphine | 3 |
| Ropivacaine + Clonidine | 6 |
| Ropivacaine + Dexamethasone | 4.5 |
Patients are called 1-3 days post-operatively to assess when the analgesia of their nerve block wore off (NCT03117140)
Timeframe: 1-3 days post-operative
| Intervention | minutes (Median) |
|---|---|
| Plain Ropivacaine | 911 |
| Ropivacaine + Buprenorphine | 1026.5 |
| Ropivacaine + Clonidine | 1181 |
| Ropivacaine + Dexamethasone | 982 |
Patients are called 1-3 days post-operatively to assess when motor component of their nerve block wore off (NCT03117140)
Timeframe: Day 1-3
| Intervention | minutes (Median) |
|---|---|
| Plain Ropivacaine | 1120 |
| Ropivacaine + Buprenorphine | 1198 |
| Ropivacaine + Clonidine | 1090 |
| Ropivacaine + Dexamethasone | 1143.5 |
Blood pressure changes in Second Stage Recovery Area for patients was looked at (NCT03117140)
Timeframe: Post-op Day 0 (baseline)
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 5 |
| Ropivacaine + Buprenorphine | 1 |
| Ropivacaine + Clonidine | 5 |
| Ropivacaine + Dexamethasone | 0 |
Patients are called 1-3 days post-operatively to assess if they had any side effects of the adjuvants such as nausea, vomiting or itching. There blood pressure is looked at pre-op and compared to post-op. Any prolonged PACU (Post Anesthesia Care Unit) stay for sedation is recorded. (NCT03117140)
Timeframe: 1-3 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 1 |
| Ropivacaine + Buprenorphine | 2 |
| Ropivacaine + Clonidine | 2 |
| Ropivacaine + Dexamethasone | 0 |
Patients itching was assessed post-op in the PACU. (NCT03117140)
Timeframe: Post-op day 0 (baseline)
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 5 |
| Ropivacaine + Buprenorphine | 2 |
| Ropivacaine + Clonidine | 6 |
| Ropivacaine + Dexamethasone | 3 |
Patients are called 1-3 days post-operatively to assess if they had any side effects of the adjuvants such as nausea, vomiting or itching. There blood pressure is looked at pre-op and compared to post-op. Any prolonged PACU (Post Anesthesia Care Unit) stay for sedation is recorded. (NCT03117140)
Timeframe: 1-3 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 4 |
| Ropivacaine + Buprenorphine | 9 |
| Ropivacaine + Clonidine | 2 |
| Ropivacaine + Dexamethasone | 3 |
PACU (Post-Anesthesia Care Unit) assessment of nausea (NCT03117140)
Timeframe: Post-op day 0 (Baseline)
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 4 |
| Ropivacaine + Buprenorphine | 9 |
| Ropivacaine + Clonidine | 2 |
| Ropivacaine + Dexamethasone | 9 |
Vomiting in PACU (Post-Anesthesia Care Unit) for patients was looked at (NCT03117140)
Timeframe: Post-op Day 0 (Baseline)
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 0 |
| Ropivacaine + Buprenorphine | 1 |
| Ropivacaine + Clonidine | 0 |
| Ropivacaine + Dexamethasone | 0 |
Blood pressure changes in PACU (Post-Anesthesia Care Unit) for patients was looked at (NCT03117140)
Timeframe: Post-op Day 0 (baseline)
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 8 |
| Ropivacaine + Buprenorphine | 3 |
| Ropivacaine + Clonidine | 7 |
| Ropivacaine + Dexamethasone | 2 |
Patients are called 1-3 days post-operatively to assess pain. Pain score is 0-10 scale with 0 is no pain and 10 is most severe pain. (NCT03117140)
Timeframe: Day 1-3
| Intervention | units on a scale (Median) |
|---|---|
| Plain Ropivacaine | 4 |
| Ropivacaine + Buprenorphine | 3 |
| Ropivacaine + Clonidine | 4 |
| Ropivacaine + Dexamethasone | 3 |
Patients are called 1-3 days post-operatively to assess if they had any side effects of the adjuvants such as nausea, vomiting or itching. There blood pressure is looked at pre-op and compared to post-op. Any prolonged PACU (Post Anesthesia Care Unit) stay for sedation is recorded. (NCT03117140)
Timeframe: 1-3 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 0 |
| Ropivacaine + Buprenorphine | 3 |
| Ropivacaine + Clonidine | 2 |
| Ropivacaine + Dexamethasone | 1 |
Patients are called 1-3 days post-operatively to assess when the sensory component of their nerve block wore off (NCT03117140)
Timeframe: Day 1-3
| Intervention | minutes (Median) |
|---|---|
| Plain Ropivacaine | 923.5 |
| Ropivacaine + Buprenorphine | 982 |
| Ropivacaine + Clonidine | 940.5 |
| Ropivacaine + Dexamethasone | 1066 |
Surgical length was recorded (NCT03117140)
Timeframe: Post op Day 0 (Baseline)
| Intervention | minutes (Median) |
|---|---|
| Plain Ropivacaine | 68.5 |
| Ropivacaine + Buprenorphine | 65 |
| Ropivacaine + Clonidine | 73.5 |
| Ropivacaine + Dexamethasone | 71 |
Surgical position was recorded (NCT03117140)
Timeframe: Post-op Day 0 (Baseline)
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Beach Chair | Lateral | Supine | |
| Plain Ropivacaine | 38 | 2 | 0 |
| Ropivacaine + Buprenorphine | 31 | 6 | 3 |
| Ropivacaine + Clonidine | 31 | 7 | 2 |
| Ropivacaine + Dexamethasone | 32 | 6 | 2 |
Intrathecal (IT) hydromorphone added to intrathecally administered local anesthetics for spinal anesthesia increases patient comfort by decreasing post-operative pain. This leads to a decrease in the post-operative intravenous hydromorphone requirements. (NCT01943565)
Timeframe: 24hrs after administration of intrathecal hydromorphone
| Intervention | mg (Mean) |
|---|---|
| Hydromorphone 25mcg | 3.44 |
| Hydromorphone 50mcg | 3.11 |
| Hydromorphone 100mcg | 4.40 |
IT (intrathecal) applied local anesthetics and opioids can cause arterial and venous vasodilation leading to a decrease in afterload as well as preload. This is typically treated with volume replacement and vasopressors (acutely). Total intraoperative vasopressor use will be reported for ephedrine equivalents. (NCT01943565)
Timeframe: Intraoperatively (at time of operation)
| Intervention | mg (Mean) |
|---|---|
| Hydromorphone 25mcg | 60.98 |
| Hydromorphone 50mcg | 56.48 |
| Hydromorphone 100mcg | 45.48 |
"IT (intrathecal ) applied local anesthetics and opioids can cause arterial and venous vasodilation leading to a decrease in afterload as well as preload. This is typically treated with volume replacement and vasopressors (acutely).~Total intraoperative vasopressor use will be reported for phenylephrine equivalents." (NCT01943565)
Timeframe: Intraoperatively (at time of operation)
| Intervention | mcg (Mean) |
|---|---|
| Hydromorphone 25mcg | 751.04 |
| Hydromorphone 50mcg | 695.54 |
| Hydromorphone 100mcg | 560.11 |
intrathecally administered opioids can cause hypothermia (body temperature <95F/35C) (NCT01943565)
Timeframe: 24hrs post administration of IT hydromorphone
| Intervention | Participants (Count of Participants) |
|---|---|
| Hydromorphone 25mcg | 0 |
| Hydromorphone 50mcg | 0 |
| Hydromorphone 100mcg | 0 |
IT opioids can cause pruritus. Persistent pruritus requiring treatment will be recorded. (NCT01943565)
Timeframe: 24hrs post administration of IT hydromorphone
| Intervention | Participants (Count of Participants) |
|---|---|
| Hydromorphone 25mcg | 0 |
| Hydromorphone 50mcg | 4 |
| Hydromorphone 100mcg | 3 |
IT/IV opioids can create visual disturbances. The number of patients with visual disturbances are reported. (NCT01943565)
Timeframe: 24hrs post administration of IT hydromorphone
| Intervention | Participants (Count of Participants) |
|---|---|
| Hydromorphone 25mcg | 0 |
| Hydromorphone 50mcg | 0 |
| Hydromorphone 100mcg | 0 |
Intravenously, and to a lesser extent, intrathecally administered opioids can lead to respiratory depressions. Therefore the subjects' oxygen saturation is measured (standard clinical practice). (NCT01943565)
Timeframe: 24hrs post administration of IT hydromorphone
| Intervention | percentage oxygenated haemoglobin (Mean) |
|---|---|
| Hydromorphone 25mcg | 98.3 |
| Hydromorphone 50mcg | 99.0 |
| Hydromorphone 100mcg | 98.4 |
IV and IT opioids can induce nausea and vomiting. Outcome measure is reported as percentage of patients with nausea and vomiting requiring rescue medication. (NCT01943565)
Timeframe: 24hrs post administration of IT hydromorphone
| Intervention | Participants (Count of Participants) |
|---|---|
| Hydromorphone 25mcg | 3 |
| Hydromorphone 50mcg | 2 |
| Hydromorphone 100mcg | 2 |
Total 24 total morphine consumption post operative. (NCT01074229)
Timeframe: 1 day
| Intervention | miligrams of morphine (Mean) |
|---|---|
| Placebo | 22.75 |
| 20 cc of 0.5% Ropivacaine | 12.5 |
| 20 cc of 0.25% Ropivacaine | 17.5 |
QoR40 on the day after surgery. Quality of recovery is based on a score of 40-200. 40 being a poor recovery and 200 being a good recovery score. (NCT01074229)
Timeframe: 1 day
| Intervention | units on a scale (Median) |
|---|---|
| PLACEBO | 152 |
| 20 cc of 0.5% Ropivacaine | 180 |
| 20 cc of 0.25% Ropivacaine | 180 |
Opioid consumption in oral morphine equivalents taken by the subject for pain during the first 24 hours post hospital discharge (NCT01075074)
Timeframe: 24 hours
| Intervention | mEq of PO morphine equivalent (Mean) |
|---|---|
| Ropivacaine 0.5% | 40 |
| Normal Saline | 78 |
| Ropivacaine 0.25% | 39 |
Area under the numeric rating scale for pain versus time (min) curve during the post anesthesia care admission. Numeric rating scale 0 to 10 with 0 equals no pain and 10 equals worst pain imaginable. (NCT01075074)
Timeframe: Post Operative
| Intervention | score on a scale * minutes (Median) |
|---|---|
| Ropivacaine 0.5% | 210 |
| Normal Saline | 405 |
| Ropivacaine 0.25% | 210 |
The quality of recovery questionnaire (QOR40) is a 40 question assessment of patient recovery following surgery. It evaluates 5 domains of recovery: pain, emotional status, physical comfort, physical independence, and support. Each question is scores on a 1 to 5 Likert scale with total scores ranging for 40, representing poor recovery, to 200, representing outstanding recovery. (NCT01075074)
Timeframe: 24 hours after surgery
| Intervention | units on a scale (Median) |
|---|---|
| Ropivacaine 0.5% | 172 |
| Normal Saline | 157 |
| Ropivacaine 0.25% | 173 |
Elapsed time from post anesthesia care unit to readiness to hospital discharge. Assessment were made using the modified post anesthetic discharge scoring system. This assess 5 criteria: vital signs, activity and mental status, pain nausea and/or vomiting, surgical bleed, and intake and output. A score greater than or equal to 9 (on a 0 to 10 scale) is considered ready for discharge. (NCT01075074)
Timeframe: 24 hours
| Intervention | minutes (Median) |
|---|---|
| Ropivacaine 0.5% | 90 |
| Normal Saline | 120 |
| Ropivacaine 0.25% | 90 |
"The time difference between local anesthetic injection and complete resolution of motor block -as measured on the Bromage scale:~I = free movement of feet, legs and hip = No block II = able to flex knees, with free movement of feet = Mild block III = unable to flex knees, but with free movement of feet = Moderate block IV = unable to move legs or feet = Complete block" (NCT03305575)
Timeframe: 6 hours
| Intervention | minutes (Mean) |
|---|---|
| Chloroprocaine | 75 |
| Bupivacaine | 99 |
The time difference between local anesthetic injection and complete resolution of sensory block. The sensory level was tested using a blunt needle tip along the patient's demratomal distribution of the spinal anesthetic. (NCT03305575)
Timeframe: 6 hours
| Intervention | minutes (Mean) |
|---|---|
| Chloroprocaine | 127 |
| Bupivacaine | 210 |
The time difference between local anesthetic injection and patient's walking for the first time postoperatively. (NCT03305575)
Timeframe: 6 hours
| Intervention | minutes (Mean) |
|---|---|
| Chloroprocaine | 110 |
| Bupivacaine | 179 |
The time difference between local anesthetic injection and the patient's voiding for the first time postoperatively. (NCT03305575)
Timeframe: 6 hours
| Intervention | minutes (Mean) |
|---|---|
| Chloroprocaine | 111 |
| Bupivacaine | 233 |
Cumulative hydrocodone/acetaminophen for supplemental analgesia to treat breakthrough pain for 72 hours following cesarean delivery (NCT00486902)
Timeframe: 72 hours
| Intervention | tablets (Median) |
|---|---|
| Ketamine | 10 |
| Placebo | 9 |
Number of subject reporting disturbing dreams at 72 hours post cesarean delivery (NCT00486902)
Timeframe: 72 hours
| Intervention | participants (Number) |
|---|---|
| Ketamine | 0 |
| Placebo | 0 |
Request for oral hydrocodone/acetaminophen for pain not controlled by around the clock non-steroidal antiflammatory drugs in the first 24 hours following cesarean delivery. (NCT00486902)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Ketamine | 64 |
| Placebo | 66 |
Numeric rating for pain score (0 to 10) reported at 2 weeks following cesarean delivery. Zero is no pain and 10 is worst pain imaginable. (NCT00486902)
Timeframe: 2 weeks
| Intervention | Scores on a scale (Median) |
|---|---|
| Ketamine | 2 |
| Placebo | 2.6 |
Number of subjects reporting nausea in first 24 hours following cesarean delivery (NCT00486902)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Ketamine | 27 |
| Placebo | 30 |
Number of subjects that vomited in the first 24 hours following cesarean delivery (NCT00486902)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Ketamine | 13 |
| Placebo | 13 |
Number of subjects with pruritus in the first 24 hours following cesarean delivery (NCT00486902)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Ketamine | 12 |
| Placebo | 19 |
Numeric rating of pain scores (NRS) scale (0 to 10) at time of supplemental analgesia request. Zero is no pain and 10 is worst pain imaginable. (NCT00486902)
Timeframe: 24 hours
| Intervention | Scores on a scale (Median) |
|---|---|
| Ketamine | 3 |
| Placebo | 4 |
(NCT01075646)
Timeframe: 48 hours
| Intervention | mg (Median) |
|---|---|
| Ropivacaine Colorectal Surgery | 23 |
| Saline Solution Colorectal Surgery | 52 |
| Ropivacaine Hepatic Surgery | 24.63 |
| Saline Solution Hepatic Surgery | 26.78 |
(NCT01075646)
Timeframe: at 48 hours
| Intervention | participants (Number) | |
|---|---|---|
| Yes | No | |
| Ropivacaine Colorectal Surgery | 6 | 27 |
| Ropivacaine Hepatic Surgery | 2 | 51 |
| Saline Solution Colorectal Surgery | 4 | 30 |
| Saline Solution Hepatic Surgery | 2 | 44 |
Verbal pain scale is a numeric measure of intensity pain, values range from 0 (no pain) to 10 (excruciating pain), Each patient rate the paín that feel with a number from 0 to 10. (NCT01075646)
Timeframe: At interval periods during 48 hours
| Intervention | units on a scale (Median) | ||||
|---|---|---|---|---|---|
| Verbal numeric scale 0h after surgery | Verbal numeric scale 6h after surgery | Verbal numeric scale 12h after surgery | Verbal numeric scale 24h after surgery | Verbal numeric scale 48h after surgery | |
| Ropivacaine Colorectal Surgery | 1 | 2 | 2 | 2 | 2 |
| Ropivacaine Hepatic Surgery | 2.75 | 1.72 | 1.45 | 1.64 | 1.62 |
| Saline Solution Colorectal Surgery | 2.5 | 3 | 2 | 2 | 2 |
| Saline Solution Hepatic Surgery | 2.5 | 2.38 | 1.8 | 2 | 2.14 |
(NCT01075646)
Timeframe: During 8-15 days
| Intervention | participants (Number) | |
|---|---|---|
| Yes | No | |
| Ropivacaine Colorectal Surgery | 6 | 27 |
| Ropivacaine Hepatic Surgery | 2 | 51 |
| Saline Solution Colorectal Surgery | 10 | 24 |
| Saline Solution Hepatic Surgery | 2 | 44 |
(NCT01075646)
Timeframe: during 48 hours
| Intervention | participants (Number) | |
|---|---|---|
| Yes | No | |
| Ropivacaine Colorectal Surgery | 5 | 28 |
| Ropivacaine Hepatic Surgery | 2 | 51 |
| Saline Solution Colorectal Surgery | 6 | 28 |
| Saline Solution Hepatic Surgery | 6 | 40 |
(NCT01075646)
Timeframe: 7 Days (from Day 8-15)
| Intervention | hours (Median) | ||
|---|---|---|---|
| Sitting in the chair | Deambulation | Solid food intake | |
| Ropivacaine Colorectal Surgery | 46 | 72 | 96 |
| Ropivacaine Hepatic Surgery | 51.75 | 81.2 | 88 |
| Saline Solution Colorectal Surgery | 48 | 72 | 120 |
| Saline Solution Hepatic Surgery | 43.2 | 87.37 | 79.79 |
Nausea and vomiting was recorded using a 0-10 Likert scale (0 = no nausea; 10 = vomiting) on postoperative day 1. Higher scores represent a worse outcome. (NCT03549234)
Timeframe: postoperative day 1
| Intervention | score on a scale (Median) |
|---|---|
| Erector Spinae (Single Injection) | 0 |
| Paravertebral (Single Injection) | 0 |
Range scale minimum 0, maximum 10. Lower pain scores are considered a better outcome, higher pain scores are considered a worse outcome. (NCT03549234)
Timeframe: 1 day (PACU pain scores)
| Intervention | score on a scale (Median) |
|---|---|
| Erector Spinae (Single Injection) | 3.0 |
| Paravertebral (Single Injection) | 0 |
Number of oxycodone tablets (in mg) taken by the participant after discharge from the recovery room was recorded during follow-up on postoperative day 1. (NCT03549234)
Timeframe: postoperative day 1
| Intervention | mg oxycodone (Median) |
|---|---|
| Erector Spinae (Single Injection) | 5 |
| Paravertebral (Single Injection) | 10 |
This outcome measure reflects the total amount of opioid administered in the operating room and recovery room perioperatively. Specific time points are not applicable since operating room and recovery room times differ among subjects. (NCT03549234)
Timeframe: up to 1 day, in the OR and PACU
| Intervention | morphine equivalents (Median) |
|---|---|
| Erector Spinae (Single Injection) | 2.0 |
| Paravertebral (Single Injection) | 1.4 |
(NCT03549234)
Timeframe: postoperative day 1
| Intervention | awakenings (Median) |
|---|---|
| Erector Spinae (Single Injection) | 0 |
| Paravertebral (Single Injection) | 0 |
This was recorded as the time at which a participant subjectively noticed that the nerve block was wearing off and sensation was returning. (NCT03549234)
Timeframe: postoperative day 1
| Intervention | hours (Median) |
|---|---|
| Erector Spinae (Single Injection) | 17.7 |
| Paravertebral (Single Injection) | 16.0 |
The occurrence of PONV will be registered during the PACU (NCT03035942)
Timeframe: 4h
| Intervention | Participants (Count of Participants) |
|---|---|
| O Group | 3 |
| D Group | 9 |
| S Group | 9 |
The occurrence of localized or generalized itching (patients who answered yes or no) (NCT03035942)
Timeframe: 24 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| O Group | 4 |
| D Group | 7 |
| S Group | 8 |
Pain were assessed every 15 minutes during postanesthesia care unit, where zero meant no pain and 10 the worst imaginable pain (higher values represent worse outcome). Twenty four hours after surgery, patients were asked to describe the highest pain score (NRS) during ward stay. (NCT03035942)
Timeframe: 24 hours
| Intervention | Score on a scale (NRS) (Median) |
|---|---|
| D Group | 0 |
| O Group | 5 |
| S Group | 2 |
Quality of Recovery Questionnaire (QoR-40). Minimum score 40 (very poor quality of recovery) and maximun score 200 (excellent quality of recovery). Higher scores mean better outcome (NCT03035942)
Timeframe: Twenty four hours after surgery by a blinded investigator
| Intervention | Score on a scale (Median) |
|---|---|
| O Group | 184 |
| D Group | 187 |
| S Group | 185 |
Forced expiratory volume in 1 sec (FEV1) preoperatively and at 24 - hour interval. Then the values were analyzed as percentage in change from per-surgery measurement (post-surgery/pre-surgery). (NCT01949480)
Timeframe: Preoperatively and postoperatively
| Intervention | percentage in change from per-surgery (Mean) |
|---|---|
| Traditional Approach Paravertebral Nerve Block | 0.561 |
| Ultrasound Assisted Paravertebral Nerve Block | 0.571 |
Forced vital capacity (FVC) measured preoperatively and at 24 - hour interval. Then values were analyzed as percentage in change from per-surgery measurement (post-surgery/pre-surgery). (NCT01949480)
Timeframe: Preoperatively and postoperatively
| Intervention | percentage in change from per-surgery (Mean) |
|---|---|
| Traditional Approach Paravertebral Nerve Block | 0.551 |
| Ultrasound Assisted Paravertebral Nerve Block | 0.504 |
Inspiratory Volume as measured by incentive spirometer preoperatively and at 24 hours post PCA initiation. The data is reported as a percentage in change from per-surgery measurements (post-surgery/pre-surgery). (NCT01949480)
Timeframe: Preoperatively and Postoperatively
| Intervention | percentage in change from per-surgery (Mean) |
|---|---|
| Traditional Approach Paravertebral Nerve Block | 0.658 |
| Ultrasound Assisted Paravertebral Nerve Block | 0.716 |
Inspired oxygen concentration and SpO2 preoperatively and at 24 - hour interval. Value reported is an average of the preoperative and the 24-hour postoperative SpO2 measurements. (NCT01949480)
Timeframe: Pre-operatively and at 24 hour post-operative
| Intervention | Percentage of SpO2 (Mean) |
|---|---|
| Traditional Approach Paravertebral Nerve Block | 95 |
| Ultrasound Assisted Paravertebral Nerve Block | 94 |
The number of local anesthetic boluses over 24- hour period post PCA initiation will also be recorded. (NCT01949480)
Timeframe: 24 hours postoperatively
| Intervention | Number of boluses requested (Mean) |
|---|---|
| Traditional Approach Paravertebral Nerve Block | 27.5 |
| Ultrasound Assisted Paravertebral Nerve Block | 48 |
Hydromorphone (Dilaudid) consumption or opiate equivalent at 24-hour interval post PCA initiation at the post-anesthesia care unit (PACU). (NCT01949480)
Timeframe: 24 hours after patient-controlled analgesia (PCA) was initiated
| Intervention | mg (Mean) |
|---|---|
| Traditional Approach Paravertebral Nerve Block | 5.75 |
| Ultrasound Assisted Paravertebral Nerve Block | 6.38 |
Peak expiratory flow rate preoperatively (PEF) and at 24 - hour interval. Then values were analyzed as percentage in change from per-surgery measurement (post-surgery/pre-surgery). (NCT01949480)
Timeframe: Preoperatively and postoperatively
| Intervention | percentage in change from per-surgery (Mean) |
|---|---|
| Traditional Approach Paravertebral Nerve Block | 0.568 |
| Ultrasound Assisted Paravertebral Nerve Block | 0.542 |
Respiratory rate (RR) per minute after surgery. (NCT01949480)
Timeframe: 24 hours postoperatively
| Intervention | breaths per one minute (Mean) |
|---|---|
| Traditional Approach Paravertebral Nerve Block | 17 |
| Ultrasound Assisted Paravertebral Nerve Block | 17.7 |
Sensory level as assessed by temperature and pin prick test assessed every 5 min for 30 min after nerve block as defined as the patient returning to their bed. Data below are in number of patients who didn't have any change during the ice and pin prik test. (NCT01949480)
Timeframe: 6 assessments starting 5 minutes after nerve block and ending 30 minutes after nerve block.
| Intervention | Participants (Count of Participants) |
|---|---|
| Traditional Approach Paravertebral Nerve Block | 3 |
| Ultrasound Assisted Paravertebral Nerve Block | 1 |
The total local anesthetic infusions over 24- hour period. (NCT01949480)
Timeframe: 24 hours postoperatively
| Intervention | mL (Mean) |
|---|---|
| Traditional Approach Paravertebral Nerve Block | 173 |
| Ultrasound Assisted Paravertebral Nerve Block | 186 |
Total Number of Local Anesthetic bolus doses given within the 24-hours post-operatively. (NCT01949480)
Timeframe: postoperatively, up to 24 hours
| Intervention | number of boluses (Mean) |
|---|---|
| Traditional Approach Paravertebral Nerve Block | 1 |
| Ultrasound Assisted Paravertebral Nerve Block | 2 |
The pain level assessed using an 11-point numerical rating scale (NRS) with 0 indicating no pain and 10 indicating the worst pain possible with deep breathing and rest at 24 hours post PCA initiation. (NCT01949480)
Timeframe: 24 hours post PCA initiation
| Intervention | units on a scale (Mean) | |
|---|---|---|
| NRS at rest after 24 hrs | NRS during deep inspiration at 24 hrs | |
| Traditional Approach Paravertebral Nerve Block | 1.73 | 4 |
| Ultrasound Assisted Paravertebral Nerve Block | 2.92 | 4.77 |
Estimated blood loss will be measured in (mL) on the day of surgery after completing the procedure. Blood loss will be categorized as >200 mL vs. <= 200 mL. (NCT01688596)
Timeframe: day of surgery after procedure completion
| Intervention | Participants (Count of Participants) |
|---|---|
| No Treatment | 2 |
| Bupivacaine | 2 |
Length of hospital stay will be measured on the day of surgery after completing the procedure to when the patient is discharged from the hospital. Length of stay will be categorized as less than 24 hours vs. greater than or equal to 24 hours. (NCT01688596)
Timeframe: from time surgery completed to time patient discharged
| Intervention | Participants (Count of Participants) |
|---|---|
| No Treatment | 36 |
| Bupivacaine | 30 |
Operating time measured in minutes (NCT01688596)
Timeframe: start to end of patient's surgery
| Intervention | minutes (Mean) |
|---|---|
| No Treatment | 73.3 |
| Bupivacaine | 63.8 |
"Postoperative pain is measured on day of surgery after trocar incisions are closed and injected with local anesthetic. Postoperative pain is evaluated with the Numerical Rating Scale (NRS) at 24 hrs after the surgery. The Numerical Rating Scale is a scale from 0 to 10 that measures pain severity, where 0 equates to no pain and 10 equates to unable to move." (NCT01688596)
Timeframe: 24 hours
| Intervention | units on a scale (Mean) |
|---|---|
| No Treatment | 3.5 |
| Bupivacaine | 4.0 |
"Postoperative pain is measured on day of surgery after trocar incisions are closed and injected with local anesthetic. Postoperative pain is evaluated with the Numerical Rating Scale (NRS) at 6 hrs after the surgery. The Numerical Rating Scale is a scale from 0 to 10 that measures pain severity, where 0 equates to no pain and 10 equates to unable to move." (NCT01688596)
Timeframe: 6 hours
| Intervention | units on a scale (Mean) |
|---|---|
| No Treatment | 4.7 |
| Bupivacaine | 4.3 |
"Postoperative pain is measured on day of surgery after trocar incisions are closed and injected with local anesthetic. Postoperative pain is evaluated with the Numerical Rating Scale (NRS) at 4 hrs after the surgery. The Numerical Rating Scale is a scale from 0 to 10 that measures pain severity, where 0 equates to no pain and 10 equates to unable to move." (NCT01688596)
Timeframe: 4 hours
| Intervention | units on a scale (Mean) |
|---|---|
| No Treatment | 4.1 |
| Bupivacaine | 3.4 |
Intraoperative complications include injury to bowel, bladder, blood vessels, nerves and hemorrhage. Perioperative complications include urinary tract infections, urinary retention, ileus, myocardial infarction, atrial fibrillation, pulmonary edema, atelectasis, pneumonia, renal and cerebrovascular morbidity, thromboembolic complications (DVT and PE). Postoperative complications include pulmonary, renal, and cerebrovascular morbidity, wound and vaginal vault complications (infection, separation, and dehiscence), septicemia, thromboembolic events, and re-operation. (NCT01688596)
Timeframe: From date of randomization up to 12 months
| Intervention | Participants (Count of Participants) |
|---|---|
| No Treatment | 0 |
| Bupivacaine | 0 |
24 Hour total opioid consumption translated into IV morphine equivalents. (NCT01075087)
Timeframe: 24 hours
| Intervention | miligram IV morphine equivalents (Median) |
|---|---|
| Placebo | 13 |
| Active Comparator | 7.5 |
Quality of Recovery 40 Score at 24 hours postoperative. (NCT01075087)
Timeframe: 24 hours post operatively
| Intervention | units on scale 40 (low) - 200 (high) (Median) |
|---|---|
| Placebo | 170 |
| Active Comparator | 175.5 |
24 hour total opioid consumption using IV morphine equivalents (NCT01180660)
Timeframe: 24 hours post surgery
| Intervention | miligrams (Median) |
|---|---|
| Lidocaine | 26 |
| Placebo | 36 |
"Quality of Recovery 40 on the Day After Surgery. The survey is a quality of recovery tool and a score of 40 is low and 200 is high.~The minimum score is 40 which is minimum recovery score and them maximum score is 200 which is considered better recovery." (NCT01180660)
Timeframe: 24 hours
| Intervention | units on scale 40 (low) - 200 (high) (Median) |
|---|---|
| Lidocaine | 165 |
| Placebo | 146 |
Patients will be observed with behaviors rated at regular time intervals using the CHIPPS (Children and Infants Postoperative Pain Scale) pain survey. The CHIPPS scale values range from a minimum of 0 (no pain, better outcome) to a maximum of 10 (worst pain, worse outcome). (NCT01638052)
Timeframe: 60 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| 0.25% Bupivacaine | 2 |
| 0.25% Bupivacaine + Clonidine | 1.9 |
Count of participants who will require use of rescue analgesic medication in the initial 24 hours postoperatively as recorded in the hospital or by parents at home following discharge. (NCT01638052)
Timeframe: 24 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| 0.25% Bupivacaine | 18 |
| 0.25% Bupivacaine + Clonidine | 22 |
Incidence of nausea/vomiting during 24 hour observation (NCT01638052)
Timeframe: 24 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| 0.25% Bupivacaine | 14 |
| 0.25% Bupivacaine + Clonidine | 10 |
8 reviews available for bupivacaine and Emesis, Postoperative
| Article | Year |
|---|---|
Impact of Transversus Abdominis Plane Block With Bupivacaine or Ropivacaine Versus Intrathecal Morphine on Opioid-related Side Effects After Cesarean Delivery: A Meta-analysis of Randomized Controlled Trials.
Topics: Abdominal Muscles; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Female; Humans; Morphine; Pa | 2021 |
The efficacy and safety of peri-tonsillar administrated agents on pain treatment after pediatric tonsillectomy: A network meta-analysis.
Topics: Analgesics; Analgesics, Opioid; Bupivacaine; Child; Dexamethasone; Double-Blind Method; Humans; Keta | 2023 |
The effect of bupivacaine on postoperative pain following thyroidectomy: a systematic review and meta-analysis.
Topics: Analgesics; Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Humans; Pain, Postoperative; Pos | 2020 |
Comparison of liposomal bupivacaine infiltration versus interscalene nerve block for pain control in total shoulder arthroplasty: A meta-analysis of randomized control trails.
Topics: Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Shoulder; Bupivacaine; Humans; Le | 2017 |
Efficacy of Intrathecal Fentanyl for Cesarean Delivery: A Systematic Review and Meta-analysis of Randomized Controlled Trials With Trial Sequential Analysis.
Topics: Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics | 2020 |
The efficacy of liposomal bupivacaine compared with traditional peri-articular injection for pain control following total knee arthroplasty: an updated meta-analysis of randomized controlled trials.
Topics: Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; Humans; Incidence; Length of Stay; | 2019 |
The Efficacy of Liposomal Bupivacaine Using Periarticular Injection in Total Knee Arthroplasty: A Systematic Review and Meta-Analysis.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; Hu | 2017 |
The Efficacy of Liposomal Bupivacaine Using Periarticular Injection in Total Knee Arthroplasty: A Systematic Review and Meta-Analysis.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; Hu | 2017 |
The Efficacy of Liposomal Bupivacaine Using Periarticular Injection in Total Knee Arthroplasty: A Systematic Review and Meta-Analysis.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; Hu | 2017 |
The Efficacy of Liposomal Bupivacaine Using Periarticular Injection in Total Knee Arthroplasty: A Systematic Review and Meta-Analysis.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; Hu | 2017 |
Comparison of peri-articular liposomal bupivacaine and standard bupivacaine for postsurgical analgesia in total knee arthroplasty: A systematic review and meta-analysis.
Topics: Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; Dru | 2017 |
138 trials available for bupivacaine and Emesis, Postoperative
| Article | Year |
|---|---|
Sensory block duration after spinal anaesthesia supplemented with intravenous dexamethasone: a randomised controlled double-blinded trial.
Topics: Anesthesia, Spinal; Anesthetics, Local; Blood Glucose; Bupivacaine; Dexamethasone; Double-Blind Meth | 2023 |
Dexamethasone Plus Bupivacaine Versus Bupivacaine in Bilateral Transincisional Paravertebral Block in Lumbar Spine Surgeries: A Randomized Controlled Trial.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Dexamethasone; Double-Blind Method; | 2023 |
On-demand (SOS) analgesia through Transversus Abdominis Plane (TAP) catheter route for post-operative pain relief in Emergency Laparotomies-a non-randomised interventional study (STAPLE trial).
Topics: Abdominal Muscles; Analgesia; Bupivacaine; Catheters; Humans; Laparotomy; Pain Management; Pain, Pos | 2023 |
Efficacy of intraperitoneal bupivacaine, hydrocortisone, and magnesium sulfate in different combinations for pain relief after laparoscopic ovarian cystectomy: a double-blind randomized controlled trial.
Topics: Adolescent; Adult; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Double-Blind Method; F | 2020 |
A randomized controlled trial on analgesic effect of repeated Quadratus Lumborum block versus continuous epidural analgesia following laparoscopic nephrectomy.
Topics: Adult; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Female; Humans; Lap | 2019 |
Optimal intrathecal hyperbaric bupivacaine dose with opioids for cesarean delivery: a prospective double-blinded randomized trial.
Topics: Adult; Anesthesia, Obstetrical; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Cesarean | 2017 |
Effect of adding midazolam to bupivacaine during rectus sheath block: a randomised controlled trial.
Topics: Adjuvants, Anesthesia; Adult; Anesthetics, Local; Bupivacaine; Herniorrhaphy; Humans; Midazolam; Ner | 2018 |
The efficacy of ultrasound-guided type-I and type-II pectoral nerve blocks for postoperative analgesia after breast augmentation: A prospective, randomised study.
Topics: Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Bupivacaine | 2019 |
Prospective, Randomized, Controlled Comparison of Bupivacaine versus Liposomal Bupivacaine for Pain Management after Unilateral Delayed Deep Inferior Epigastric Perforator Free Flap Reconstruction.
Topics: Abdominal Muscles; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Drug Costs; Female; Humans; Le | 2018 |
Effect of adding nalbuphine to intrathecal bupivacaine with morphine on postoperative nausea and vomiting and pruritus after elective cesarean delivery: a randomized double blinded study.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivaca | 2019 |
Effectiveness of Intraperitoneal Bupivacaine in Reducing Postoperative Morphine Used among Total Abdominal Hysterectomy Patients at Phramongkutklao Hospital.
Topics: Adult; Analgesia, Patient-Controlled; Anesthetics, Local; Antiemetics; Bupivacaine; Female; Humans; | 2016 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Loc | 2020 |
A randomized study of surgical site infiltration with bupivacaine or ketamine for pain relief in children following cleft palate repair.
Topics: Anesthesia, Local; Anesthetics, Dissociative; Anesthetics, Local; Bupivacaine; Child; Child Behavior | 2013 |
The effects of different doses of caudal morphine with levobupivacaine on postoperative vomiting and quality of analgesia after circumcision.
Topics: Analgesics, Opioid; Anesthesia, Caudal; Anesthetics, Local; Bupivacaine; Child; Circumcision, Male; | 2014 |
Intrathecal fentanyl decreases the optimal effect site concentration of propofol during spinal anaesthesia.
Topics: Adjuvants, Anesthesia; Aged; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Bupiv | 2014 |
Comparative hemodynamic advantages of subarachnoid administration of atypical and non-atypical opioids.
Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Appendectomy; Bupivacaine; Female | 2014 |
The effect of transversus abdominis plane blocks on postoperative pain in laparoscopic colorectal surgery: a prospective, randomized, double-blind trial.
Topics: Abdominal Muscles; Aged; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind Method; F | 2014 |
The effect of transversus abdominis plane blocks on postoperative pain in laparoscopic colorectal surgery: a prospective, randomized, double-blind trial.
Topics: Abdominal Muscles; Aged; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind Method; F | 2014 |
The effect of transversus abdominis plane blocks on postoperative pain in laparoscopic colorectal surgery: a prospective, randomized, double-blind trial.
Topics: Abdominal Muscles; Aged; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind Method; F | 2014 |
The effect of transversus abdominis plane blocks on postoperative pain in laparoscopic colorectal surgery: a prospective, randomized, double-blind trial.
Topics: Abdominal Muscles; Aged; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind Method; F | 2014 |
Dexamethasone versus a combination of dexamethasone and ondansetron as prophylactic antiemetic in patients receiving intrathecal morphine for caesarean section.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Antiemetics; Bupivacaine; Cesarean Section; Dexam | 2014 |
General or Spinal Anaesthetic for Vaginal Surgery in Pelvic Floor Disorders (GOSSIP): a feasibility randomised controlled trial.
Topics: Aged; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Spinal; Anest | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
Analgesia and respiratory function after laparoscopic cholecystectomy in patients receiving ultrasound-guided bilateral oblique subcostal transversus abdominis plane block: a randomized double-blind study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; C | 2015 |
SUBTENON BUPIVACAINE INJECTION FOR POSTOPERATIVE PAIN RELIEF FOLLOWING PEDIATRIC STRABISMUS SURGERY: A RANDOMIZED CONTROLLED DOUBLE BLIND TRIAL.
Topics: Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Double-Blind Method; Humans; Injections; P | 2015 |
The Efficacy of Levobupivacaine Hydrochloride-Dexamethasone Infiltration for Post-Tonsillectomy Pain in Adults.
Topics: Adolescent; Adult; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents; Blood Loss, Surgical; B | 2015 |
Efficacy of dexmedetomidine as an adjuvant in paravertebral block in breast cancer surgery.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; Breast Ne | 2016 |
Subtenon block combined with general anesthesia for vitreoretinal surgery improves postoperative analgesia in adult: a randomized controlled trial.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Huma | 2016 |
Ultrasound-guided transversus abdominis plane block for postoperative analgesia in living liver donors: A prospective, randomized, double-blinded clinical trial.
Topics: Abdominal Muscles; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Ant | 2017 |
A local anesthetic pump reduces postoperative pain and narcotic and antiemetic use in breast reconstruction surgery: a randomized controlled trial.
Topics: Adult; Anesthetics, Local; Antiemetics; Bupivacaine; Double-Blind Method; Drug Delivery Systems; Fem | 2008 |
A local anesthetic pump reduces postoperative pain and narcotic and antiemetic use in breast reconstruction surgery: a randomized controlled trial.
Topics: Adult; Anesthetics, Local; Antiemetics; Bupivacaine; Double-Blind Method; Drug Delivery Systems; Fem | 2008 |
A local anesthetic pump reduces postoperative pain and narcotic and antiemetic use in breast reconstruction surgery: a randomized controlled trial.
Topics: Adult; Anesthetics, Local; Antiemetics; Bupivacaine; Double-Blind Method; Drug Delivery Systems; Fem | 2008 |
A local anesthetic pump reduces postoperative pain and narcotic and antiemetic use in breast reconstruction surgery: a randomized controlled trial.
Topics: Adult; Anesthetics, Local; Antiemetics; Bupivacaine; Double-Blind Method; Drug Delivery Systems; Fem | 2008 |
Epidural ketamine for postoperative analgesia in the elderly.
Topics: Abdomen; Aged; Analgesia, Epidural; Analgesics; Anesthetics, Local; Bupivacaine; Double-Blind Method | 2008 |
Thoracic epidural analgesia in post-thoracotomy patients: comparison of three different concentrations of levobupivacaine and sufentanil.
Topics: Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivac | 2009 |
[Epidural analgesia versus femoral or femoral-sciatic nerve block after total knee replacement: comparison of efficacy and safety].
Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Anesthetics, Local; Arthroplasty, Replacement, Knee; B | 2009 |
Subtenon block compared to intravenous fentanyl for perioperative analgesia in pediatric cataract surgery.
Topics: Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cataract Extraction; Child; Child, Preschool; D | 2009 |
A comparison of continuous femoral nerve block (CFNB) and continuous epidural infusion (CEI) in postoperative analgesia and knee rehabilitation after total knee arthroplasty (TKA).
Topics: Adult; Aged; Analgesia, Epidural; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; | 2009 |
A comparison of continuous femoral nerve block (CFNB) and continuous epidural infusion (CEI) in postoperative analgesia and knee rehabilitation after total knee arthroplasty (TKA).
Topics: Adult; Aged; Analgesia, Epidural; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; | 2009 |
A comparison of continuous femoral nerve block (CFNB) and continuous epidural infusion (CEI) in postoperative analgesia and knee rehabilitation after total knee arthroplasty (TKA).
Topics: Adult; Aged; Analgesia, Epidural; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; | 2009 |
A comparison of continuous femoral nerve block (CFNB) and continuous epidural infusion (CEI) in postoperative analgesia and knee rehabilitation after total knee arthroplasty (TKA).
Topics: Adult; Aged; Analgesia, Epidural; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; | 2009 |
Bilateral infraorbital nerve blocks decrease postoperative pain but do not reduce time to discharge following outpatient nasal surgery.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, General; Anesthetics, Local; Bu | 2009 |
The effects of topical levobupivacaine on morbidity in pediatric tonsillectomy patients.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Doubl | 2009 |
Two different doses of caudal neostigmine co-administered with levobupivacaine produces analgesia in children.
Topics: Analgesia; Anesthesia, Caudal; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child, Presch | 2009 |
Continuous incisional infusion of local anesthetic in pediatric patients following open heart surgery.
Topics: Adolescent; Anesthetics, Local; Bupivacaine; Cardiac Surgical Procedures; Child; Child, Preschool; D | 2009 |
Adding sufentanil to levobupivacaine or ropivacaine intrathecal anaesthesia affects the minimum local anaesthetic dose required.
Topics: Adult; Amides; Anesthesia Recovery Period; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, | 2009 |
Is there an advantage in using low-dose intrathecal bupivacaine for cesarean section?
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Bl | 2009 |
The effects of intrathecal levobupivacaine and bupivacaine in the elderly.
Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Blood Pressure; Bupivacaine; Fentanyl; Heart Rate; Hum | 2009 |
Unilateral paravertebral block: an alternative to conventional spinal anaesthesia for inguinal hernia repair.
Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia Recovery Period; Anesthesia, Spinal; Anesthetics, In | 2010 |
A randomized comparison of low doses of hyperbaric bupivacaine in combined spinal-epidural anesthesia for cesarean delivery.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesth | 2009 |
Postoperative analgesia with minidose intrathecal morphine for bipolar hip prosthesis in extremely elderly patients.
Topics: Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Hip; Bupivacai | 2009 |
Brief report: improved pain relief using intermittent bupivacaine injections at the donor site after breast reconstruction with deep inferior epigastric perforator flap.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local | 2010 |
Effects of intrathecal fentanyl on quality of spinal anesthesia in children undergoing inguinal hernia repair.
Topics: Abdominal Pain; Adolescent; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Bupiva | 2010 |
Efficacy of intrathecal morphine with epidural ropivacaine infusion for postcesarean analgesia.
Topics: Adult; Amides; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cesarean Se | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Area | 2010 |
The effect of adding magnesium sulphate to epidural bupivacaine and fentanyl in elective caesarean section using combined spinal-epidural anaesthesia: a prospective double blind randomised study.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Ane | 2010 |
Plasma levels of bupivacaine and its metabolites after subacromial infusions in concentrations 2.5 or 5.0 mg/ml.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Chromatography, | 2011 |
Buprenorphine enhances and prolongs the postoperative analgesic effect of bupivacaine in patients receiving infragluteal sciatic nerve block.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthetics, Local; Ankle; Bupivacaine; B | 2010 |
Effect of epidural clonidine on minimum local anesthetic concentration (ED50) of levobupivacaine for caudal block in children.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Analgesia, Epidural; Anesthesia, Caudal; Anestheti | 2011 |
General anesthesia with thoracic paravertebral block for modified radical mastectomy.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; A | 2010 |
ED(50) and ED(95) of intrathecal bupivacaine in morbidly obese patients undergoing cesarean delivery.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, | 2011 |
ED(50) and ED(95) of intrathecal bupivacaine in morbidly obese patients undergoing cesarean delivery.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, | 2011 |
ED(50) and ED(95) of intrathecal bupivacaine in morbidly obese patients undergoing cesarean delivery.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, | 2011 |
ED(50) and ED(95) of intrathecal bupivacaine in morbidly obese patients undergoing cesarean delivery.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, | 2011 |
Intrathecal hydromorphone added to hyperbaric bupivacaine for postoperative pain relief after knee arthroscopic surgery: a prospective, randomised, controlled trial.
Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Arthroscopy; Bupivacaine; Chi-Squ | 2012 |
Intrathecal hydromorphone added to hyperbaric bupivacaine for postoperative pain relief after knee arthroscopic surgery: a prospective, randomised, controlled trial.
Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Arthroscopy; Bupivacaine; Chi-Squ | 2012 |
Intrathecal hydromorphone added to hyperbaric bupivacaine for postoperative pain relief after knee arthroscopic surgery: a prospective, randomised, controlled trial.
Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Arthroscopy; Bupivacaine; Chi-Squ | 2012 |
Intrathecal hydromorphone added to hyperbaric bupivacaine for postoperative pain relief after knee arthroscopic surgery: a prospective, randomised, controlled trial.
Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Arthroscopy; Bupivacaine; Chi-Squ | 2012 |
Effects of intravenous dexmedetomidine on low-dose bupivacaine spinal anaesthesia in elderly patients.
Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Dexmedetomidine; Double-Blind Method; Flu | 2012 |
Effects of intravenous dexmedetomidine on low-dose bupivacaine spinal anaesthesia in elderly patients.
Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Dexmedetomidine; Double-Blind Method; Flu | 2012 |
Effects of intravenous dexmedetomidine on low-dose bupivacaine spinal anaesthesia in elderly patients.
Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Dexmedetomidine; Double-Blind Method; Flu | 2012 |
Effects of intravenous dexmedetomidine on low-dose bupivacaine spinal anaesthesia in elderly patients.
Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Dexmedetomidine; Double-Blind Method; Flu | 2012 |
Anesthetic and analgesic effects in patients undergoing a lumbar laminectomy of spinal, epidural or a combined spinal-epidural block with the addition of morphine.
Topics: Adolescent; Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesi | 2012 |
Local infiltration analgesia with levobupivacaine compared with intrathecal morphine in total hip arthroplasty patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Local; A | 2012 |
Single intrathecal fentanyl for combined spinal epidural anesthesia confers no advantage over hemodynamic effects in elderly patients.
Topics: Aged; Aged, 80 and over; Aging; Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics, Intravenous; | 2012 |
Bilateral multi-injection iliohypogastric-ilioinguinal nerve block in conjunction with neuraxial morphine is superior to neuraxial morphine alone for postcesarean analgesia.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Bupivacaine; Cesarean Section; Double-Blind Metho | 2012 |
The effect of preemptive analgesia with bupivacaine on postoperative pain of inguinal hernia repair under spinal anesthesia: a randomized clinical trial.
Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Double-Blind Method; | 2013 |
Caudal dexmedetomidine combined with bupivacaine inhibit the response to hernial sac traction in children undergoing inguinal hernia repair.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthesia, Caudal; Anesthesia | 2013 |
Caudal dexmedetomidine combined with bupivacaine inhibit the response to hernial sac traction in children undergoing inguinal hernia repair.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthesia, Caudal; Anesthesia | 2013 |
Caudal dexmedetomidine combined with bupivacaine inhibit the response to hernial sac traction in children undergoing inguinal hernia repair.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthesia, Caudal; Anesthesia | 2013 |
Caudal dexmedetomidine combined with bupivacaine inhibit the response to hernial sac traction in children undergoing inguinal hernia repair.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthesia, Caudal; Anesthesia | 2013 |
[Single-dose intraincisional levobupivacaine infiltration in caesarean postoperative analgesia: a placebo-controlled double-blind randomized trial].
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cesarean Section; Double-Blind Method; E | 2013 |
[Single-dose intraincisional levobupivacaine infiltration in caesarean postoperative analgesia: a placebo-controlled double-blind randomized trial].
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cesarean Section; Double-Blind Method; E | 2013 |
[Single-dose intraincisional levobupivacaine infiltration in caesarean postoperative analgesia: a placebo-controlled double-blind randomized trial].
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cesarean Section; Double-Blind Method; E | 2013 |
[Single-dose intraincisional levobupivacaine infiltration in caesarean postoperative analgesia: a placebo-controlled double-blind randomized trial].
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cesarean Section; Double-Blind Method; E | 2013 |
Comparison of retrobulbar analgesics for evisceration.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Case-Control Studies; Codeine; Etha | 2002 |
[Additive retrobulbar anesthesia in surgery of retinal detachment with general anesthesia. Reduced postoperative pain and stress response].
Topics: Aged; Anesthesia, General; Anesthesia, Local; Blood Glucose; Bupivacaine; Female; Humans; Hydrocorti | 2002 |
Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; D | 2002 |
Effect of route of buprenorphine on recovery and postoperative analgesic requirement in paediatric patients.
Topics: Adolescent; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Local; Bupivacaine; Bupreno | 2002 |
Continuous epidural infusion of large concentration/small volume versus small concentration/large volume of levobupivacaine for postoperative analgesia.
Topics: Adolescent; Adult; Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Blood Pressure | 2003 |
The effect of spinal bupivacaine in combination with either epidural clonidine and/or 0.5% bupivacaine administered at the incision site on postoperative outcome in patients undergoing lumbar laminectomy.
Topics: Adrenergic alpha-Agonists; Aged; Anesthesia Recovery Period; Anesthesia, Epidural; Anesthesia, Spina | 2003 |
Prophylactic ip injection of bupivacaine and/or morphine does not improve postoperative analgesia after laparoscopic gynecologic surgery.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Conscious Sedation; Double-B | 2003 |
Prophylactic ip injection of bupivacaine and/or morphine does not improve postoperative analgesia after laparoscopic gynecologic surgery.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Conscious Sedation; Double-B | 2003 |
Prophylactic ip injection of bupivacaine and/or morphine does not improve postoperative analgesia after laparoscopic gynecologic surgery.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Conscious Sedation; Double-B | 2003 |
Prophylactic ip injection of bupivacaine and/or morphine does not improve postoperative analgesia after laparoscopic gynecologic surgery.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Conscious Sedation; Double-B | 2003 |
Subarachnoid small-dose bupivacaine versus lidocaine for cervical cerclage.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Bupiv | 2003 |
[Neostigmine added to bupivacaine in axillary plexus block: which benefit?].
Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Bupivacaine; Fem | 2003 |
Intraoperative intravenous ketamine in combination with epidural analgesia: postoperative analgesia after renal surgery.
Topics: Adult; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, General; Anesthetics, Dissociative; Anes | 2003 |
[Blocking nociceptive afferents by retrobulbar bupivacaine does not decrease nausea and vomiting after propofol-remifentanil anaesthesia].
Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Double-Bli | 2003 |
Sub-Tenon's block reduces both intraoperative and postoperative analgesia requirement in vitreo-retinal surgery under general anaesthesia.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; | 2003 |
Epidural neostigmine produces analgesia but also sedation in women after cesarean delivery.
Topics: Adult; Analgesia; Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Cesarean Section; Fema | 2004 |
Analgesic effect of clonidine added to bupivacaine 0.125% in paediatric caudal blockade.
Topics: Adrenergic alpha-Agonists; Analgesics; Anesthesia, Caudal; Anesthetics, Local; Bupivacaine; Child, P | 2004 |
General anaesthesia combined with bilateral paravertebral blockade (T5-6) vs. general anaesthesia for laparoscopic cholecystectomy: a prospective, randomized clinical trial.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; Cholecystectom | 2004 |
Efficacy and side effect profile of varying doses of intrathecal fentanyl added to bupivacaine for labor analgesia.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Dose-Response Re | 2004 |
Postoperative pain after abdominal hysterectomy: a double-blind comparison between placebo and local anesthetic infused intraperitoneally.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Hys | 2004 |
Postoperative pain after abdominal hysterectomy: a double-blind comparison between placebo and local anesthetic infused intraperitoneally.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Hys | 2004 |
Postoperative pain after abdominal hysterectomy: a double-blind comparison between placebo and local anesthetic infused intraperitoneally.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Hys | 2004 |
Postoperative pain after abdominal hysterectomy: a double-blind comparison between placebo and local anesthetic infused intraperitoneally.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Hys | 2004 |
Is intraperitoneal levobupivacaine with epinephrine useful for analgesia following laparoscopic cholecystectomy? A randomized controlled trial.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Double-Bl | 2004 |
A comparison of selective spinal anesthesia with hyperbaric bupivacaine and general anesthesia with desflurane for outpatient knee arthroscopy.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Do | 2004 |
Continuous spinal analgesia or opioid-added continuous epidural analgesia for postoperative pain control after hip replacement.
Topics: Analgesia; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Combined; Anest | 2004 |
Dose minimization study of single-dose epidural morphine in patients undergoing hip surgery under regional anesthesia with bupivacaine.
Topics: Adolescent; Analgesia, Epidural; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Conduct | 2005 |
Spinal-induced hypotension in elderly patients with hip fracture. A comparison of glucose-free bupivacaine with glucose-free bupivacaine and fentanyl.
Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Local; Blood Pressure; Bupivacaine; Drug I | 2005 |
Caudal additives in pediatrics: a comparison among midazolam, ketamine, and neostigmine coadministered with bupivacaine.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthesia, General; Anesthetics, Intravenous; Anest | 2005 |
The persisting analgesic effect of low-dose intravenous ketamine after spinal anaesthesia for caesarean section.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Dissociative | 2005 |
Comparison of 2 concentrations of levobupivacaine in postoperative patient-controlled epidural analgesia.
Topics: Abdomen; Adolescent; Adult; Aged; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Op | 2005 |
Patient outcomes after axillary lymph node dissection for breast cancer: use of postoperative continuous local anesthesia infusion.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Axilla; Breast Neoplasms; Bupivacaine; Consciou | 2006 |
Postoperative continuous intrathecal pain treatment in children after selective dorsal rhizotomy with bupivacaine and two different morphine doses.
Topics: Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Dose-Response Relation | 2006 |
Combined propofol sedation with sub-Tenon's lidocaine/mercaine infusion for strabismus surgery in adults.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthesia, Local; Anesthetics, Combined; Anest | 2007 |
Prevention of postoperative nausea and vomiting after intrathecal morphine for Cesarean section: a randomized comparison of dexamethasone, droperidol, and a combination.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Antiemetics; Bupivacaine; Cesarean Section; Consc | 2007 |
Prevention of postoperative nausea and vomiting after intrathecal morphine for Cesarean section: a randomized comparison of dexamethasone, droperidol, and a combination.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Antiemetics; Bupivacaine; Cesarean Section; Consc | 2007 |
Prevention of postoperative nausea and vomiting after intrathecal morphine for Cesarean section: a randomized comparison of dexamethasone, droperidol, and a combination.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Antiemetics; Bupivacaine; Cesarean Section; Consc | 2007 |
Prevention of postoperative nausea and vomiting after intrathecal morphine for Cesarean section: a randomized comparison of dexamethasone, droperidol, and a combination.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Antiemetics; Bupivacaine; Cesarean Section; Consc | 2007 |
[Femoral nerve block for postoperative analgesia after anterior cruciate ligament reconstruction: comparison of 2 concentrations of bupivacaine with clonidine in 3 modes of administration].
Topics: Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Non-Narcotic; Anesthetics, | 2006 |
The effect of intravenous administration of dexamethasone on postoperative pain, nausea, and vomiting after intrathecal injection of meperidine.
Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Anti-In | 2007 |
Extending low-dose epidural analgesia in labour for emergency Caesarean section - a comparison of levobupivacaine with or without fentanyl.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca | 2007 |
Comparison of caudal ketamine with or without bupivacaine in pediatric subumbilical surgery.
Topics: Abdomen; Anesthesia, Caudal; Anesthetics, Dissociative; Anesthetics, Local; Bupivacaine; Child; Chil | 2007 |
Hearing loss after spinal anesthesia: the effect of different infusion solutions.
Topics: Anesthesia, Spinal; Audiometry, Pure-Tone; Auditory Threshold; Bupivacaine; Dizziness; Female; Fenta | 2007 |
Clonidine 1 microg/kg is a safe and effective adjuvant to plain bupivacaine in spinal anesthesia in adolescents.
Topics: Adjuvants, Pharmaceutic; Adolescent; Anesthesia, Spinal; Bupivacaine; Child; Clonidine; Double-Blind | 2007 |
Prospective, double-blinded, randomized, placebo-controlled comparison of local anesthetic and nonsteroidal anti-inflammatory drugs for postoperative pain management after laparoscopic surgery.
Topics: Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Cholecystectom | 2007 |
Safety and efficacy of patient controlled epidural analgesia following pediatric spinal surgery.
Topics: Adolescent; Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Anesthesia, General; Anesthet | 2008 |
A prospective randomized double-blind study to determine the effect of thoracic epidural neostigmine on postoperative ileus after abdominal aortic surgery.
Topics: Adult; Aged; Anesthesia, Epidural; Anesthetics, Local; Aorta, Abdominal; Bupivacaine; Cholinesterase | 2008 |
Spinal anesthesia with sequential administration of plain and hyperbaric bupivacaine provides satisfactory analgesia with hemodynamic stability in cesarean section.
Topics: Adrenergic Agents; Adult; Analgesia; Analgesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; | 2008 |
Intrathecal morphine in anesthesia for cesarean delivery: dose-response relationship for combinations of low-dose intrathecal morphine and spinal bupivacaine.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spina | 2008 |
Intrathecal morphine in anesthesia for cesarean delivery: dose-response relationship for combinations of low-dose intrathecal morphine and spinal bupivacaine.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spina | 2008 |
Intrathecal morphine in anesthesia for cesarean delivery: dose-response relationship for combinations of low-dose intrathecal morphine and spinal bupivacaine.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spina | 2008 |
Intrathecal morphine in anesthesia for cesarean delivery: dose-response relationship for combinations of low-dose intrathecal morphine and spinal bupivacaine.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spina | 2008 |
Intrathecal morphine in anesthesia for cesarean delivery: dose-response relationship for combinations of low-dose intrathecal morphine and spinal bupivacaine.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spina | 2008 |
Intrathecal morphine in anesthesia for cesarean delivery: dose-response relationship for combinations of low-dose intrathecal morphine and spinal bupivacaine.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spina | 2008 |
Intrathecal morphine in anesthesia for cesarean delivery: dose-response relationship for combinations of low-dose intrathecal morphine and spinal bupivacaine.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spina | 2008 |
Intrathecal morphine in anesthesia for cesarean delivery: dose-response relationship for combinations of low-dose intrathecal morphine and spinal bupivacaine.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spina | 2008 |
Intrathecal morphine in anesthesia for cesarean delivery: dose-response relationship for combinations of low-dose intrathecal morphine and spinal bupivacaine.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spina | 2008 |
Caudal morphine in paediatric patients: a comparison of two different doses in children after major urogenital surgery.
Topics: Analgesics, Opioid; Anesthesia, Caudal; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Do | 1998 |
Postoperative patient-controlled epidural analgesia with opioid bupivacaine mixtures.
Topics: Abdomen; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; | 1998 |
Bupivacaine 0.01% and/or epinephrine 0.5 microg/ml improve epidural fentanyl analgesia after cesarean section.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; B | 1998 |
Comparison of epidural anaesthesia with ropivacaine 0.5% and bupivacaine 0.5% for caesarean section.
Topics: Adolescent; Adult; Amides; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Apgar | 1998 |
Side-effects of epidural infusions of opioid bupivacaine mixtures.
Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, | 1998 |
Delayed postoperative gastric emptying following intrathecal morphine and intrathecal bupivacaine.
Topics: Absorption; Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; | 1999 |
A comparison of two concentrations of bupivacaine and adrenaline with and without fentanyl in paediatric inguinal herniorrhaphy.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analgesics; Analgesics, Opioid; Analysis of Va | 1999 |
Postoperative extradural infusions in children: preliminary data from a comparison of bupivacaine/diamorphine with plain ropivacaine.
Topics: Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child; Costs and Cost Analysis; Drug Co | 1999 |
Single-injection paravertebral block compared to general anaesthesia in breast surgery.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Genera | 1999 |
Single-injection paravertebral block compared to general anaesthesia in breast surgery.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Genera | 1999 |
Single-injection paravertebral block compared to general anaesthesia in breast surgery.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Genera | 1999 |
Single-injection paravertebral block compared to general anaesthesia in breast surgery.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Genera | 1999 |
Single-injection paravertebral block compared to general anaesthesia in breast surgery.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Genera | 1999 |
Single-injection paravertebral block compared to general anaesthesia in breast surgery.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Genera | 1999 |
Single-injection paravertebral block compared to general anaesthesia in breast surgery.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Genera | 1999 |
Single-injection paravertebral block compared to general anaesthesia in breast surgery.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Genera | 1999 |
Single-injection paravertebral block compared to general anaesthesia in breast surgery.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Genera | 1999 |
Intravenous ketoprofen and epidural sufentanil analgesia in children after combined spinal-epidural anaesthesia.
Topics: Adolescent; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Spinal; Anest | 1999 |
Continuous spinal anaesthesia or continuous epidural anaesthesia for post-operative pain control after hip replacement?
Topics: Aged; Analgesia; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics, Local; | 1999 |
Peribulbar anesthesia with either 0.75% ropivacaine or a 2% lidocaine and 0.5% bupivacaine mixture for vitreoretinal surgery: a double-blinded study.
Topics: Amides; Anesthesia, Conduction; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Double-Blind | 1999 |
Combined epidural-spinal opioid-free anaesthesia and analgesia for hysterectomy.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthesia, Spinal; Anesthe | 1999 |
Comparison of intravenous or epidural patient-controlled analgesia in the elderly after major abdominal surgery.
Topics: Abdomen; Aged; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, | 2000 |
Additional droperidol, not butorphanol, augments epidural fentanyl analgesia following anorectal surgery.
Topics: Adjuvants, Anesthesia; Anal Canal; Analgesia, Epidural; Analgesics, Opioid; Analysis of Variance; An | 2000 |
Day-case laparoscopy: a comparison of prophylactic opioid, NSAID or local anesthesia for postoperative analgesia.
Topics: Adult; Ambulatory Surgical Procedures; Analgesia; Analgesics, Opioid; Anesthesia Recovery Period; An | 2000 |
The dose-response of intrathecal sufentanil added to bupivacaine for labor analgesia.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bradycardia; Bupivacaine; Dos | 2000 |
Subarachnoid meperidine (Pethidine) causes significant nausea and vomiting during labor. The Duke Women's Anesthesia Research Group.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Intravenous; Ane | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Preventing postoperative pain by local anesthetic instillation after laparoscopic gynecologic surgery: a placebo-controlled comparison of bupivacaine and ropivacaine.
Topics: Adolescent; Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind M | 2000 |
Development and evaluation of combined rectus sheath and ilioinguinal blocks for abdominal gynaecological surgery.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Dru | 1999 |
Effects of peribulbar bupivacaine as an adjunct to general anaesthesia on peri-operative outcome following retinal detachment surgery.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Conduction; Anesthesi | 2000 |
Effect of pre-incision skin infiltration on post-hysterectomy pain--a double-blind randomized controlled trial.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Local; Anesthetics, Local; Bupivacain | 2000 |
Does adrenaline improve epidural bupivacaine and fentanyl analgesia after abdominal surgery?
Topics: Abdomen; Adrenergic alpha-Agonists; Analgesia, Epidural; Analgesics, Opioid; Analysis of Variance; A | 2000 |
Patient-controlled interscalene analgesia with ropivacaine 0.2% versus bupivacaine 0.15% after major open shoulder surgery: the effects on hand motor function.
Topics: Adolescent; Adult; Aged; Amides; Analgesia, Patient-Controlled; Anesthetics, Local; Bupivacaine; Cat | 2001 |
Safety and efficacy of peribulbar block as adjunct to general anaesthesia for paediatric ophthalmic surgery.
Topics: Adolescent; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Blood Pressure; Bupivacaine | 2001 |
Patient-controlled epidural analgesia versus continuous epidural analgesia after total knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesi | 2001 |
Combined pre- and post-surgical bupivacaine wound infiltrations decrease opioid requirements after knee ligament reconstruction.
Topics: Adult; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Anterior Cruciate Ligament; Bupi | 2001 |
A comparison of single dose caudal tramadol, tramadol plus bupivacaine and bupivacaine administration for postoperative analgesia in children.
Topics: Analgesics, Opioid; Anesthesia, Caudal; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Do | 2001 |
Pain after laparoscopic cholecystectomy: the effect and timing of incisional and intraperitoneal bupivacaine.
Topics: Adult; Anesthesia, General; Anesthetics, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Female; | 2001 |
Pain after laparoscopic cholecystectomy: the effect and timing of incisional and intraperitoneal bupivacaine.
Topics: Adult; Anesthesia, General; Anesthetics, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Female; | 2001 |
Pain after laparoscopic cholecystectomy: the effect and timing of incisional and intraperitoneal bupivacaine.
Topics: Adult; Anesthesia, General; Anesthetics, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Female; | 2001 |
Pain after laparoscopic cholecystectomy: the effect and timing of incisional and intraperitoneal bupivacaine.
Topics: Adult; Anesthesia, General; Anesthetics, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Female; | 2001 |
Intercostal nerve block with Bupivacaine for post-thoracotomy pain relief in children.
Topics: Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child; Female; Humans; Intercostal Nerves; Male | 2001 |
Intraoperative single-shot "3-in-1" femoral nerve block with ropivacaine 0.25%, ropivacaine 0.5% or bupivacaine 0.25% provides comparable 48-hr analgesia after unilateral total knee replacement.
Topics: Adult; Aged; Amides; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupiva | 2001 |
[Continuous epidural administration of droperidol to prevent postoperative nausea and vomiting].
Topics: Adult; Aged; Analgesia, Epidural; Antiemetics; Bupivacaine; Buprenorphine; Dose-Response Relationshi | 2002 |
Cost-effectiveness of analgesia after Caesarean section. A comparison of intrathecal morphine and epidural PCA.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioi | 2002 |
Postoperative pain relief in children undergoing tympanomastoid surgery: is a regional block better than opioids?
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Double-Bli | 2002 |
Effect of delayed supine positioning after induction of spinal anaesthesia for caesarean section.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Blood Pressure; Bupivacaine; | 2002 |
Prophylactic ondansetron is effective in the treatment of nausea and vomiting but not on pruritus after cesarean delivery with intrathecal sufentanil-morphine.
Topics: Adult; Anesthesia, Obstetrical; Antiemetics; Bupivacaine; Cesarean Section; Double-Blind Method; Fem | 2002 |
Levobupivacaine for axillary brachial plexus block: a pharmacokinetic and clinical comparison in patients with normal renal function or renal disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Axilla; Brachial Plexus; Bupivacaine | 2002 |
22 other studies available for bupivacaine and Emesis, Postoperative
| Article | Year |
|---|---|
Post-operative nausea and vomiting (PONV) observed in a clinical study designed to assess the analgesic effects of intravenous and subcutaneous methadone in dogs.
Topics: Analgesia; Analgesics, Opioid; Animals; Bupivacaine; Dog Diseases; Dogs; Methadone; Pain, Postoperat | 2022 |
Does Intrathecal Morphine in Spinal Anesthesia Have a Role in Modern Multimodal Analgesia for Primary Total Joint Arthroplasty?
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Replacement, Hip; Arthroplast | 2018 |
Intrathecal morphine in combination with bupivacaine: a comparative study following caesarean section.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cesarean Section; Female; Hu | 2013 |
Comparison of 2 Methods of Local Anesthetic-Based Injection as Part of a Multimodal Approach to Pain Management After Total Knee Arthroplasty.
Topics: Aged; Amides; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, | 2015 |
Contact topical anesthesia for strabismus surgery in adult patients.
Topics: Administration, Ophthalmic; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; B | 2015 |
Reducing Opioid Adverse Events: A Safe Way to Improve Outcomes.
Topics: Accidental Falls; Adult; Aged; Bupivacaine; Colonoscopy; Drug Substitution; Female; Florida; Hernior | 2016 |
Predicting postoperative vomiting among orthopedic patients receiving patient-controlled epidural analgesia using SVM and LR.
Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Anesthetics, Local; Are | 2016 |
Maternal satisfaction after spinal anaesthesia for caesarean deliveries.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Back Pai | 2009 |
Continuous peripheral nerve blocks for postoperative analgesia in children: feasibility and side effects in a cohort study of 339 catheters.
Topics: Adolescent; Amides; Anesthetics, Local; Bupivacaine; Catheterization; Child; Child, Preschool; Cohor | 2009 |
Neuraxial anesthesia for cesarean delivery: what criteria define the "optimal" technique?
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; | 2009 |
Postoperative analgesia.
Topics: Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Loca | 2010 |
Low-dose sequential combined spinal-epidural anaesthesia in elective Stark caesarean section: a preliminary cohort study.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics, Local; Bradycardia | 2010 |
Spinal anesthesia in children: no longer an anathema!
Topics: Anesthesia, Spinal; Anesthetics, Local; Body Weight; Bupivacaine; Child; Child, Preschool; Female; H | 2010 |
Is single-shot epidural analgesia more effective than morphine patient-controlled analgesia for donor nephrectomy?
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; A | 2011 |
Limiting the dose of local anaesthetic for caesarean section under spinal anaesthesia--has the limbo bar been set too low?
Topics: Anesthesia, Local; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Section; Dose-Respo | 2012 |
Local anesthesia use for laparoscopic cholecystectomy.
Topics: Adult; Aged; Analgesics; Anesthesia, Local; Antiemetics; Bupivacaine; Cholecystectomy, Laparoscopic; | 2004 |
Optimal dose range of epidural naloxone to reduce nausea in patients receiving epidural morphine.
Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; Dose- | 2004 |
Epidural analgesia in children: planning, organization and development of a new program.
Topics: Adolescent; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Argentina; Bupivacaine; Cat | 2007 |
Cerebral subarachnoid blood migration consecutive to a lumbar haematoma after spinal anaesthesia.
Topics: Aged; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Angioplasty, Balloon; Arteri | 2008 |
Epidural analgesia in children with cerebral palsy.
Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cerebral Palsy; Child; Con | 1998 |
Outcomes after single injection caudal epidural versus continuous infusion epidural via caudal approach for postoperative analgesia in infants and children undergoing patent ductus arteriosus ligation.
Topics: Analgesia, Epidural; Bupivacaine; Child, Preschool; Ductus Arteriosus, Patent; Humans; Infant; Infus | 1999 |
Recovery after paediatric daycase herniotomy performed under spinal anaesthesia.
Topics: Activities of Daily Living; Ambulatory Surgical Procedures; Analgesics; Anesthesia Recovery Period; | 2000 |