bupivacaine has been researched along with Edema in 25 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this case series was to report and discuss the lower limb edema from IT hydromorphone and morphine therapy and its resolution or nonrecurrence upon rotating the IT solution to fentanyl." | 7.83 | Resolution of Intrathecal Hydromorphone or Morphine-induced Peripheral Edema by Opioid Rotation to Fentanyl: A Case Series. ( Hayek, SM; Tornero-Bold, M; Veizi, E, 2016) |
| "This study was designed to assess the correlation between the neuroprotective effect of dexmedetomidine and oxidative stress, neural inflammation and mast cell stability in rats with bupivacaine-induced sciatic nerve toxicity." | 7.79 | The protective effect of dexmedetomidine on bupivacaine-induced sciatic nerve inflammation is mediated by mast cells. ( Çelik, F; Evliyaoğlu, O; Firat, U; Karaman, H; Kaya, S; Tokgöz, O; Tüfek, A, 2013) |
| " The aim of this study was to compare the effects of bupivacaine via sciatic block with a systemic NSAID on oedema and hyperalgesia and on indices of systemic inflammation as measured by cytokines and prostaglandin E2 production in a model of peripheral inflammation in rats." | 7.76 | Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats. ( Beloeil, H; Benhamou, D; Combettes, E; Mazoit, JX, 2010) |
| " To elucidate potential mechanisms, the authors examined effects of bupivacaine or tetrodotoxin, administered to rats by ipsilateral or contralateral sciatic blockade or systemically, on carrageenan-induced hind paw hyperalgesia, edema, and stimulated cytokine production in circulating blood cells." | 7.73 | Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 1): hyperalgesia, edema, and systemic cytokines. ( Ababneh, Z; Beloeil, H; Berde, CB; Chung, R; Mulkern, RV; Zurakowski, D, 2006) |
| "The authors previously showed that bupivacaine and tetrodotoxin via contralateral or ipsilateral sciatic block, but not systemically, attenuate local edema and hyperalgesia induced by carrageenan hind paw injection in rats." | 7.73 | Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 2): cytokines and p38 mitogen-activated protein kinases in dorsal root ganglia and spinal cord. ( Beloeil, H; Berde, CB; Ji, RR, 2006) |
| "Surgery did not increase gut wall water content, but acute oedema formation resulted in the peri-resectional mesenterial tissue, more prominently so in the bupivacaine group." | 7.72 | Epidural anaesthesia with bupivacaine does not cause increased oedema in small gut anatomoses in pigs. ( Dall, R; Fedder, A; Laurberg, S; Rodt, SA, 2004) |
| "The purpose of this case series was to report and discuss the lower limb edema from IT hydromorphone and morphine therapy and its resolution or nonrecurrence upon rotating the IT solution to fentanyl." | 3.83 | Resolution of Intrathecal Hydromorphone or Morphine-induced Peripheral Edema by Opioid Rotation to Fentanyl: A Case Series. ( Hayek, SM; Tornero-Bold, M; Veizi, E, 2016) |
| "This study was designed to assess the correlation between the neuroprotective effect of dexmedetomidine and oxidative stress, neural inflammation and mast cell stability in rats with bupivacaine-induced sciatic nerve toxicity." | 3.79 | The protective effect of dexmedetomidine on bupivacaine-induced sciatic nerve inflammation is mediated by mast cells. ( Çelik, F; Evliyaoğlu, O; Firat, U; Karaman, H; Kaya, S; Tokgöz, O; Tüfek, A, 2013) |
| " The aim of this study was to compare the effects of bupivacaine via sciatic block with a systemic NSAID on oedema and hyperalgesia and on indices of systemic inflammation as measured by cytokines and prostaglandin E2 production in a model of peripheral inflammation in rats." | 3.76 | Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats. ( Beloeil, H; Benhamou, D; Combettes, E; Mazoit, JX, 2010) |
| " In this study, we evaluated the effect of bupivacaine administered via a nerve block or via a systemic route on the spinal expression of PGE2 and COX in a model of peripheral inflammation in rats." | 3.75 | The effect of a peripheral block on inflammation-induced prostaglandin E2 and cyclooxygenase expression in rats. ( Beloeil, H; Benhamou, D; Gentili, M; Mazoit, JX, 2009) |
| " To elucidate potential mechanisms, the authors examined effects of bupivacaine or tetrodotoxin, administered to rats by ipsilateral or contralateral sciatic blockade or systemically, on carrageenan-induced hind paw hyperalgesia, edema, and stimulated cytokine production in circulating blood cells." | 3.73 | Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 1): hyperalgesia, edema, and systemic cytokines. ( Ababneh, Z; Beloeil, H; Berde, CB; Chung, R; Mulkern, RV; Zurakowski, D, 2006) |
| "The authors previously showed that bupivacaine and tetrodotoxin via contralateral or ipsilateral sciatic block, but not systemically, attenuate local edema and hyperalgesia induced by carrageenan hind paw injection in rats." | 3.73 | Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 2): cytokines and p38 mitogen-activated protein kinases in dorsal root ganglia and spinal cord. ( Beloeil, H; Berde, CB; Ji, RR, 2006) |
| " Following the unilateral intraplantar injection of BmK venom into rat hind paw, it was found: 1) BmK venom induced an edematogenic response, spontaneous pain and pain hypersensitivity in a dose-dependent manner; 2) the paw edema and flare were induced rapidly and restricted at the injected paw for about 24-48 h; 3) the monophasic tonic spontaneous pain manifested as continuous paw flinching and lifting/licking of the injected paw and lasted for more than 2 h; 4) the detectable thermal hypersensitivity to radiant heat stimuli was just at the injected side for about 72-96 h; 5) the mechanical hypersensitivity to von Frey filaments was evoked surprisingly to be the bilateral and mirror-like for about 2-3 weeks; 6) morphine, indomethacin and bupivacaine could suppress BmK venom-induced pain responses with different intensity and time courses." | 3.73 | Rat pain-related responses induced by experimental scorpion BmK sting. ( Bai, ZT; Chai, ZF; Ji, YH; Liu, T; Pang, XY, 2006) |
| "The purpose of this study was to evaluate the effect of local anesthetic blockade of afferent innervation on the development of capsaicin-induced edema in the rat temporomandibular joint (TMJ) region and on reflex jaw muscle activity." | 3.72 | Capsaicin-induced joint inflammation is not blocked by local anesthesia. ( Haas, DA; Hu, JW; Tang, ML, 2004) |
| "Surgery did not increase gut wall water content, but acute oedema formation resulted in the peri-resectional mesenterial tissue, more prominently so in the bupivacaine group." | 3.72 | Epidural anaesthesia with bupivacaine does not cause increased oedema in small gut anatomoses in pigs. ( Dall, R; Fedder, A; Laurberg, S; Rodt, SA, 2004) |
| "A 43-year-old woman suffered from recurrent localized swellings and an eczematous dermatitis starting 1 day after an injection of lidocaine." | 3.69 | Delayed-type hypersensitivity to subcutaneous lidocaine with tolerance to articaine: confirmation by in vivo and in vitro tests. ( Bircher, AJ; Messmer, SL; Rufli, T; Surber, C, 1996) |
| "We have assessed the effects of intraplantar local anaesthetics (bupivacaine and lignocaine) on carrageenan-induced oedema, mechanical allodynia and spinal c-fos protein expression." | 3.69 | Effects of local anaesthetics on carrageenan-evoked inflammatory nociceptive processing in the rat. ( Besson, JM; Buritova, J; Fletcher, D; Honoré, P, 1996) |
| "Tetrodotoxin was less efficacious for inhibiting the TNF-alpha transport and the rise in receptor expression and for inhibiting the axonal transport ex vivo." | 1.36 | Effects of a bupivacaine nerve block on the axonal transport of Tumor Necrosis Factor-alpha (TNF-alpha) in a rat model of carrageenan-induced inflammation. ( Beloeil, H; Benhamou, D; Combettes, E; Deruddre, S; Duranteau, J; Estebe, JP; Mazoit, JX, 2010) |
| "Bupivacaine treatment caused severe tissue damage (score, 2." | 1.32 | The acute myotoxic effects of bupivacaine and ropivacaine after continuous peripheral nerve blockades. ( Bohl, JRE; Braun, PM; Fink, RHA; Graf, BM; Hacke, N; Martin, E; Seif, C; Sinner, B; Zink, W, 2003) |
| "Inflammation found in temporomandibular disorders and rheumatoid arthritis may result from mediators released by pain-sensing neurons." | 1.31 | Local anesthesia does not block mustard-oil-induced temporomandibular inflammation. ( Haas, DA; Hu, JW; Wong, JK, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (20.00) | 18.2507 |
| 2000's | 13 (52.00) | 29.6817 |
| 2010's | 6 (24.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kara, YS | 1 |
| Hapa, O | 1 |
| Işın, Y | 1 |
| Kılıç, Aİ | 1 |
| Havitçioğlu, H | 1 |
| Tüfek, A | 1 |
| Kaya, S | 1 |
| Tokgöz, O | 1 |
| Firat, U | 1 |
| Evliyaoğlu, O | 1 |
| Çelik, F | 1 |
| Karaman, H | 1 |
| Christensen, J | 1 |
| Matzen, LH | 1 |
| Vaeth, M | 1 |
| Wenzel, A | 1 |
| Schou, S | 1 |
| Veizi, E | 1 |
| Tornero-Bold, M | 1 |
| Hayek, SM | 1 |
| Rajalakshmi, AR | 1 |
| Kumar, MA | 1 |
| Fry, R | 1 |
| Ring, P | 1 |
| Van Le, B | 1 |
| Harish, S | 1 |
| Beloeil, H | 5 |
| Gentili, M | 1 |
| Benhamou, D | 3 |
| Mazoit, JX | 4 |
| Deruddre, S | 1 |
| Combettes, E | 2 |
| Estebe, JP | 1 |
| Duranteau, J | 1 |
| Fornet Ruiz, I | 1 |
| Palacio Abizanda, FJ | 1 |
| Gilsanz, F | 1 |
| Zink, W | 1 |
| Seif, C | 1 |
| Bohl, JRE | 1 |
| Hacke, N | 1 |
| Braun, PM | 1 |
| Sinner, B | 1 |
| Martin, E | 1 |
| Fink, RHA | 1 |
| Graf, BM | 1 |
| Tang, ML | 1 |
| Haas, DA | 2 |
| Hu, JW | 2 |
| Fedder, A | 1 |
| Dall, R | 1 |
| Laurberg, S | 1 |
| Rodt, SA | 1 |
| Griffiths, RJ | 1 |
| O'Sullivan, G | 1 |
| Ababneh, Z | 1 |
| Chung, R | 1 |
| Zurakowski, D | 1 |
| Mulkern, RV | 1 |
| Berde, CB | 2 |
| Ji, RR | 1 |
| Bai, ZT | 1 |
| Liu, T | 1 |
| Chai, ZF | 1 |
| Pang, XY | 1 |
| Ji, YH | 1 |
| Bircher, AJ | 1 |
| Messmer, SL | 1 |
| Surber, C | 1 |
| Rufli, T | 1 |
| Buritova, J | 1 |
| Fletcher, D | 2 |
| Honoré, P | 1 |
| Besson, JM | 1 |
| Gentili, ME | 1 |
| Samii K, K | 1 |
| Ozzeybek, D | 1 |
| Koca, U | 1 |
| Elar, Z | 1 |
| Olguner, M | 1 |
| Hakgüder, G | 1 |
| Fu, KY | 1 |
| Light, AR | 1 |
| Maixner, W | 1 |
| Wong, JK | 1 |
| Hoefflin, SM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparing the Efficacy of Local Anesthetics in Mohs Surgery[NCT03871478] | 105 participants (Anticipated) | Interventional | 2019-10-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for bupivacaine and Edema
| Article | Year |
|---|---|
[Clinical safety with ropivacaine administration].
Topics: Adult; Amides; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Bupivacaine; Edema; | 2002 |
2 trials available for bupivacaine and Edema
| Article | Year |
|---|---|
A comparison of ice wrap and subacromial injection for postoperative pain and edema control following arthroscopic rotator cuff repair.
Topics: Adult; Aged; Anesthetics, Local; Arthroscopy; Bupivacaine; Cryotherapy; Edema; Female; Humans; Ice; | 2020 |
Efficiency of bupivacaine versus lidocaine and methylprednisolone versus placebo to reduce postoperative pain and swelling after surgical removal of mandibular third molars: a randomized, double-blinded, crossover clinical trial.
Topics: Adult; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Cross-Over Studies; Do | 2013 |
22 other studies available for bupivacaine and Edema
| Article | Year |
|---|---|
The protective effect of dexmedetomidine on bupivacaine-induced sciatic nerve inflammation is mediated by mast cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Local; Animals; Antioxidants; Aryldialkylphosphat | 2013 |
Resolution of Intrathecal Hydromorphone or Morphine-induced Peripheral Edema by Opioid Rotation to Fentanyl: A Case Series.
Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Drug Implants; Edema; Female; Fentanyl; H | 2016 |
Hyaluronidase hypersensitivity: A rare complication of peribulbar block.
Topics: Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Cataract Extraction; Drug Hypersensitivity; | 2016 |
Delayed retrobulbar haemorrhage associated with a repeat sub-Tenon's block.
Topics: Acetaminophen; Acetazolamide; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents | 2008 |
Quadriceps fat pad edema: sonographic depiction and sonographically guided steroid injection.
Topics: Adipose Tissue; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Edema; Humans; Injections | 2009 |
The effect of a peripheral block on inflammation-induced prostaglandin E2 and cyclooxygenase expression in rats.
Topics: Animals; Bupivacaine; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Edema; Gene Expression Regul | 2009 |
Effects of a bupivacaine nerve block on the axonal transport of Tumor Necrosis Factor-alpha (TNF-alpha) in a rat model of carrageenan-induced inflammation.
Topics: Anesthetics, Local; Animals; Axonal Transport; Bupivacaine; Carrageenan; Disease Models, Animal; Ede | 2010 |
Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Dinoprostone; Dis | 2010 |
The acute myotoxic effects of bupivacaine and ropivacaine after continuous peripheral nerve blockades.
Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Edema; Female; In Situ Nick-End Labeling; Microsco | 2003 |
Capsaicin-induced joint inflammation is not blocked by local anesthesia.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Bupivacaine; Capsaicin; Dose-Response Relationshi | 2004 |
Epidural anaesthesia with bupivacaine does not cause increased oedema in small gut anatomoses in pigs.
Topics: Analgesics, Opioid; Analysis of Variance; Anastomosis, Surgical; Anesthesia, Epidural; Anesthetics, | 2004 |
C1-esterase inhibitor deficiency and elective caesarean section.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Section; Complement C1 Inactiva | 2005 |
Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 1): hyperalgesia, edema, and systemic cytokines.
Topics: Animals; Bupivacaine; Carrageenan; Drug Therapy, Combination; Edema; Hindlimb; Inflammation; Male; R | 2006 |
Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 2): cytokines and p38 mitogen-activated protein kinases in dorsal root ganglia and spinal cord.
Topics: Animals; Bupivacaine; Carrageenan; Cytokines; Drug Therapy, Combination; Edema; Ganglia, Spinal; Hin | 2006 |
Rat pain-related responses induced by experimental scorpion BmK sting.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupivacain | 2006 |
Delayed-type hypersensitivity to subcutaneous lidocaine with tolerance to articaine: confirmation by in vivo and in vitro tests.
Topics: Adult; Anesthetics, Local; Benzocaine; Bupivacaine; Carticaine; Cross Reactions; Dermatitis, Allergi | 1996 |
Effects of local anaesthetics on carrageenan-evoked inflammatory nociceptive processing in the rat.
Topics: Anesthetics, Local; Animals; Bupivacaine; Carrageenan; Edema; Inflammation; Lidocaine; Male; Nocicep | 1996 |
The effect of a sciatic nerve block on the development of inflammation in carrageenan injected rats.
Topics: Anesthetics, Local; Animals; Body Temperature; Bupivacaine; Carrageenan; Edema; Epinephrine; Excipie | 1999 |
Glycerol trinitrate plus epidural sympathetic block in the ischemia of glans penis.
Topics: Anesthesia, Epidural; Anesthetics, Local; Anticoagulants; Autonomic Nerve Block; Bupivacaine; Child; | 1999 |
Relationship between nociceptor activity, peripheral edema, spinal microglial activation and long-term hyperalgesia induced by formalin.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Bupivacaine; Chronic Disease; Dose-Response Relations | 2000 |
Local anesthesia does not block mustard-oil-induced temporomandibular inflammation.
Topics: Anesthetics, Local; Animals; Arthritis; Bupivacaine; Dose-Response Relationship, Drug; Edema; Electr | 2001 |
Decreasing prolonged swelling and pain associated with deep plane face lifts.
Topics: Bupivacaine; Dexamethasone; Diphenhydramine; Edema; Humans; Pain, Postoperative; Postoperative Compl | 1992 |