bupivacaine has been researched along with Dystocia in 6 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Dystocia: Slow or difficult OBSTETRIC LABOR or CHILDBIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To prospectively evaluate if a high rate of epidural analgesia (EDA) with bupivacaine-sufentanil is consistent with a low rate of caesarean section, instrumental deliveries and dystocia and to evaluate maternal and fetal adverse effects of sufentanil." | 3.71 | A high rate of epidural analgesia with bupivacaine-sufentanil is consistent with a low rate of caesarean section and instrumental deliveries. ( Hanson, U; Lindeberg, SN; Thorén, T, 2001) |
| "Dystocia is characterized by abnormal progress of labor and is a common contemporary indication for cesarean delivery in the United States." | 2.71 | Local anesthetic requirements are greater in dystocia than in normal labor. ( Panni, MK; Segal, S, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Panni, MK | 1 |
| Segal, S | 1 |
| Halpern, SH | 1 |
| Muir, H | 1 |
| Breen, TW | 1 |
| Campbell, DC | 1 |
| Barrett, J | 1 |
| Liston, R | 1 |
| Blanchard, JW | 1 |
| Claquin, C | 1 |
| Lespagnol, M | 1 |
| Lavigne, F | 1 |
| Heluin, G | 1 |
| Frydman, R | 1 |
| Masliah-Planchon, R | 1 |
| Nageotte, MP | 1 |
| Larson, D | 1 |
| Rumney, PJ | 1 |
| Sidhu, M | 1 |
| Hollenbach, K | 1 |
| Lindeberg, SN | 1 |
| Thorén, T | 1 |
| Hanson, U | 1 |
| Conte, M | 1 |
| Ruf, H | 1 |
| Blanc, B | 1 |
| Rosello, M | 1 |
| Agher, JP | 1 |
| Dupont, S | 1 |
| Adrai, J | 1 |
| Delpont, PJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Individualized Timing of Analgesia on the Effectiveness of Labor Analgesia: a Randomized Controlled Trial[NCT02920489] | 200 participants (Actual) | Interventional | 2016-08-31 | Completed | |||
| A Retrospective Case-controlled Study of the Association Between Request to Discontinue Second Stage Labor Epidural Analgesia and Risk of Instrumental Vaginal Delivery[NCT00443560] | 2,162 participants (Actual) | Observational | 2006-01-31 | Completed | |||
| A Randomized Trial of the Impact of Three Labor Analgesia Techniques on Labor Duration in Spontaneously Laboring Nulliparous Parturients[NCT01982838] | 129 participants (Actual) | Interventional | 2010-07-31 | Terminated (stopped due to Low qualified candidate enrollment) | |||
| A Randomized Trial of the Impact of Three Labor Analgesia Techniques on Labor Duration in Nulliparous Labor Inductions[NCT01982851] | 134 participants (Actual) | Interventional | 2010-07-31 | Terminated (stopped due to low qualified candidate enrollment) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Time in minutes from initiation of labor analgesia until delivery of the infant (NCT00443560)
Timeframe: Time form initiation of labor analgesia to delivery (up to 24 hours)
| Intervention | minutes (Median) |
|---|---|
| Instrumental Vaginal Delivery (IVD) | 420 |
| Spontaneous Vaginal Delivery (SVD) | 300 |
At the request of the obstetric provider, second stage analgesia density was decreased by decreasing the basal infusion rate if there was dissatisfaction with the progress of labor or a perceived inability to push. The basal infusion was never totally discontinued. (NCT00443560)
Timeframe: Second stage of labor up to 3 hours
| Intervention | participants (Number) |
|---|---|
| Instrumental Vaginal Delivery (IVD) | 146 |
| Spontaneous Vaginal Delivery (SVD) | 51 |
Pain not responding to epidural analgesia in the first stage of labor was treated with bolus dose of bupivacaine 1.25 mg/mL or lidocaine 10 mg/mL, 10 to 15 mL. If pain relief was obtained the infusion concentration was increased. If the patient had no pain relief following the bolus injection, the epidural catheter was replaced. (NCT00443560)
Timeframe: Supplemental analgesia in first stage of labor (<24 hours)
| Intervention | participants (Number) | ||
|---|---|---|---|
| Supplemental bolus | Infusion increase | Concentration increase | |
| Instrumental Vaginal Delivery (IVD) | 802 | 149 | 32 |
| Spontaneous Vaginal Delivery (SVD) | 243 | 87 | 19 |
3 trials available for bupivacaine and Dystocia
| Article | Year |
|---|---|
Local anesthetic requirements are greater in dystocia than in normal labor.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Bupivacaine; Cesarean Sectio | 2003 |
Local anesthetic requirements are greater in dystocia than in normal labor.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Bupivacaine; Cesarean Sectio | 2003 |
Local anesthetic requirements are greater in dystocia than in normal labor.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Bupivacaine; Cesarean Sectio | 2003 |
Local anesthetic requirements are greater in dystocia than in normal labor.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Bupivacaine; Cesarean Sectio | 2003 |
A multicenter randomized controlled trial comparing patient-controlled epidural with intravenous analgesia for pain relief in labor.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics; Analg | 2004 |
Epidural analgesia compared with combined spinal-epidural analgesia during labor in nulliparous women.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthet | 1997 |
Epidural analgesia compared with combined spinal-epidural analgesia during labor in nulliparous women.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthet | 1997 |
Epidural analgesia compared with combined spinal-epidural analgesia during labor in nulliparous women.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthet | 1997 |
Epidural analgesia compared with combined spinal-epidural analgesia during labor in nulliparous women.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthet | 1997 |
3 other studies available for bupivacaine and Dystocia
| Article | Year |
|---|---|
[Peridural analgesia with 0.375 percent bupivacaine in labor with dystocia].
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Apgar Score; Bupivacaine; Delivery, Obstetric; | 1984 |
A high rate of epidural analgesia with bupivacaine-sufentanil is consistent with a low rate of caesarean section and instrumental deliveries.
Topics: Analgesia, Epidural; Analgesics, Opioid; Bupivacaine; Cesarean Section; Delivery, Obstetric; Dystoci | 2001 |
[The labor test under epidural analgesia. Apropos of 87 cases].
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Apgar Score; Bupivacaine; Cesarean Section; De | 1985 |