bupivacaine has been researched along with Drug Hypersensitivity in 31 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lidocaine hydrochloride is an amide-type local anesthetic, commonly used for facial plastic as well as other surgical procedures." | 5.27 | Anaphylactic reaction to lidocaine. ( Cave, RH; Kennedy, KS, 1986) |
| " We report the case of a 74-year-old man who suffered anaphylaxis, presenting with cardiovascular collapse, immediately after receiving regional anaesthesia on two separate occasions, the first involving the use of levobupivacaine and the second using ropivacaine." | 3.79 | Immediate allergic cross-reactivity to levobupivacaine and ropivacaine. ( Allaouchiche, B; Benatir, F; Boselli, E; Calderon, AL; Christin, F; Diot, N; Hautin, E; Truc, C, 2013) |
| "She had a history of serious anaphylactic reactions, including respiratory distress, hypotension and unconsciousness, to nonsteroidal anti-inflammatory drugs (Loxonin, Niflan) and antibiotics (Kefral, Minomycin)." | 1.29 | [Anesthesia in a patient with history of multiple drug allergies]. ( Fukuda, H; Hirabayashi, Y; Horiguchi, Y; Ikeno, S; Inoue, S; Mitsuhata, H; Saitoh, J; Shimizu, R, 1995) |
| "Lidocaine hydrochloride is an amide-type local anesthetic, commonly used for facial plastic as well as other surgical procedures." | 1.27 | Anaphylactic reaction to lidocaine. ( Cave, RH; Kennedy, KS, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (25.81) | 18.7374 |
| 1990's | 4 (12.90) | 18.2507 |
| 2000's | 7 (22.58) | 29.6817 |
| 2010's | 12 (38.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Güleç, H | 1 |
| Babayiğit, M | 1 |
| Kütük, S | 1 |
| Kurtay, A | 1 |
| Tutal, Z | 1 |
| Horasanlı, E | 1 |
| Rajalakshmi, AR | 1 |
| Kumar, MA | 1 |
| Vega, F | 1 |
| Argíz, L | 1 |
| Bazire, R | 1 |
| Las Heras, P | 1 |
| Blanco, C | 1 |
| Tagliero, A | 1 |
| DʼAmore, P | 1 |
| Zaiac, MN | 1 |
| Choudhary, S | 1 |
| Ueshima, H | 1 |
| Otake, H | 1 |
| Lahlou, J | 1 |
| Bensghir, M | 1 |
| Belyamani, L | 1 |
| Boulahri, T | 1 |
| Drissi Kamili, N | 1 |
| Sambrook, PJ | 1 |
| Smith, W | 1 |
| Elijah, J | 1 |
| Goss, AN | 1 |
| Gupta, A | 1 |
| Fennelly, M | 1 |
| Ramesh, V | 1 |
| Agyare, K | 1 |
| Dudley, MH | 1 |
| Fleming, SW | 1 |
| Garg, U | 1 |
| Edwards, JM | 1 |
| Benjamin, DM | 1 |
| Mazarakis, A | 1 |
| Kounis, NG | 1 |
| Calderon, AL | 1 |
| Diot, N | 1 |
| Benatir, F | 1 |
| Christin, F | 1 |
| Hautin, E | 1 |
| Truc, C | 1 |
| Allaouchiche, B | 1 |
| Boselli, E | 1 |
| Kartal, O | 1 |
| Gulec, M | 1 |
| Caliskaner, AZ | 1 |
| Sener, O | 1 |
| Hawkins, JM | 1 |
| Moore, PA | 1 |
| Cox, B | 1 |
| Durieux, ME | 1 |
| Marcus, MA | 1 |
| Balestrieri, PJ | 1 |
| Ferguson, JE | 1 |
| Berkun, Y | 1 |
| Ben-Zvi, A | 1 |
| Levy, Y | 1 |
| Galili, D | 1 |
| Shalit, M | 1 |
| Quhill, F | 1 |
| Bowling, B | 1 |
| Packard, RB | 1 |
| Patil, B | 1 |
| Agius-Fernandez, A | 1 |
| Worstmann, T | 1 |
| Brubnjak-Jevtic, V | 1 |
| Brown, DT | 1 |
| Beamish, D | 1 |
| Wildsmith, JA | 1 |
| McLeskey, CH | 1 |
| Horiguchi, Y | 1 |
| Mitsuhata, H | 1 |
| Ikeno, S | 1 |
| Fukuda, H | 1 |
| Inoue, S | 1 |
| Saitoh, J | 1 |
| Hirabayashi, Y | 1 |
| Shimizu, R | 1 |
| Munoz Bellido, FJ | 1 |
| Bellido, J | 1 |
| Juan, JL | 1 |
| Moyano, JC | 1 |
| Alvarez, M | 1 |
| Bacon, GS | 1 |
| Lyons, TR | 1 |
| Wood, SH | 1 |
| Feldman, T | 1 |
| Moss, J | 1 |
| Teplinsky, K | 1 |
| Carroll, JD | 1 |
| Mehta, Y | 1 |
| Luxton, MC | 1 |
| Kennedy, KS | 1 |
| Cave, RH | 1 |
| Sehhati, G | 1 |
| Frey, R | 1 |
| Mildner, R | 1 |
| Smith, RB | 1 |
| Everett, WG | 1 |
| Nolte, H | 1 |
| Wurster, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Evaluation of Arrhythmia Mapping With a Globe-Shaped, High-Density, Multi-Electrode Mapping Catheter[NCT05373862] | 40 participants (Actual) | Interventional | 2022-07-29 | Completed | |||
| Clinical Evaluation of Arrhythmia Mapping With the Multi-Electrode OPTRELL™ Mapping Catheter[NCT04983797] | 31 participants (Actual) | Interventional | 2021-08-25 | Completed | |||
| Clinical Evaluation of Intracardiac Ultrasound With the NUVISION NAV Ultrasound Catheter[NCT05970120] | 30 participants (Anticipated) | Interventional | 2023-09-05 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Number of participants with non-serious adverse events within 7 days of index procedure associated with the use of the OPTRELL catheter were reported. An AE is any untoward medical occurrence in a participant participating in a clinical study that does not necessarily have a causal relationship with the pharmaceutical/biological agent under study. (NCT04983797)
Timeframe: Up to 7 days of index procedure at Day 0
| Intervention | Participants (Count of Participants) |
|---|---|
| OPTRELL Mapping Catheter | 0 |
Number of participants with pre-ablation mapping and clinically indicated mapping performed with the OPTRELL catheter without resort to other mapping catheters were reported. (NCT04983797)
Timeframe: Up to 72 days
| Intervention | Participants (Count of Participants) |
|---|---|
| OPTRELL Mapping Catheter | 31 |
Number of participants with SAEs within 7 days of index procedure were reported. An AE is any untoward medical occurrence in a participant whether or not related to the investigational device. SAE is any AE that results in: death, persistent or significant disability/incapacity, requires inpatient hospitalization or prolongation of existing hospitalization, is life-threatening experience, is a congenital anomaly/birth defect and may jeopardize participant and/or may require medical or surgical intervention to prevent one of the outcomes listed above. (NCT04983797)
Timeframe: Up to 7 days of index procedure at Day 0
| Intervention | Participants (Count of Participants) |
|---|---|
| OPTRELL Mapping Catheter | 3 |
Number of participants with SAEs within 7 days of index procedure related to the OPTRELL catheter were reported. An adverse event (AE) is any untoward medical occurrence in a participant whether or not related to the investigational device. SAE is any AE that results in: death, persistent or significant disability/incapacity, requires inpatient hospitalization or prolongation of existing hospitalization, is life-threatening experience, is a congenital anomaly/birth defect and may jeopardize participant and/or may require medical or surgical intervention to prevent one of the outcomes listed above. (NCT04983797)
Timeframe: Up to 7 days of index procedure at Day 0
| Intervention | Participants (Count of Participants) |
|---|---|
| OPTRELL Mapping Catheter | 0 |
Number of responders for physician assessment for ability to characterize the tissue were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for ability to characterize the tissue. (NCT04983797)
Timeframe: Up to 72 days
| Intervention | Participants (Count of Participants) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compared to the PENTARAY catheter?: Score 1 | Compared to the PENTARAY catheter?: Score 2 | Compared to the PENTARAY catheter?: Score 3 | Compared to the PENTARAY catheter?: Score 4 | Compared to the PENTARAY catheter?: Score 5 | Compared to the PENTARAY catheter?: Score 6 | Compared to the PENTARAY catheter?: Score 7 | Compared to other competitive multielectrode catheters?: Score 1 | Compared to other competitive multielectrode catheters?: Score 2 | Compared to other competitive multielectrode catheters?: Score 3 | Compared to other competitive multielectrode catheters?: Score 4 | Compared to other competitive multielectrode catheters?: Score 5 | Compared to other competitive multielectrode catheters?: Score 6 | Compared to other competitive multielectrode catheters?: Score 7 | |
| OPTRELL Mapping Catheter | 0 | 0 | 0 | 0 | 0 | 16 | 15 | 0 | 0 | 0 | 0 | 0 | 25 | 0 |
Number of responders with physician assessment for arrhythmogenicity were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for arrhythmogenicity. (NCT04983797)
Timeframe: Up to 72 days
| Intervention | Participants (Count of Participants) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compared to the PENTARAY catheter?: Score 1 | Compared to the PENTARAY catheter?: Score 2 | Compared to the PENTARAY catheter?: Score 3 | Compared to the PENTARAY catheter?: Score 4 | Compared to the PENTARAY catheter?: Score 5 | Compared to the PENTARAY catheter?: Score 6 | Compared to the PENTARAY catheter?: Score 7 | Compared to other competitive multielectrode catheters?: Score 1 | Compared to other competitive multielectrode catheters?: Score 2 | Compared to other competitive multielectrode catheters?: Score 3 | Compared to other competitive multielectrode catheters?: Score 4 | Compared to other competitive multielectrode catheters?: Score 5 | Compared to other competitive multielectrode catheters?: Score 6 | Compared to other competitive multielectrode catheters?: Score 7 | |
| OPTRELL Mapping Catheter | 0 | 0 | 0 | 2 | 5 | 10 | 14 | 0 | 0 | 0 | 0 | 5 | 19 | 1 |
Number of responders for physician assessment for catheter design were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for catheter design in OPTRELL catheter for mapping. (NCT04983797)
Timeframe: Up to 72 days
| Intervention | Participants (Count of Participants) | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ability to achieve electrode contact with cardiac tissue: Score 1 | Ability to achieve electrode contact with cardiac tissue: Score 2 | Ability to achieve electrode contact with cardiac tissue: Score 3 | Ability to achieve electrode contact with cardiac tissue: Score 4 | Ability to achieve electrode contact with cardiac tissue: Score 5 | Ability to achieve electrode contact with cardiac tissue: Score 6 | Ability to achieve electrode contact with cardiac tissue: Score 7 | Electrodes spacing: Score 1 | Electrodes spacing: Score 2 | Electrodes spacing: Score 3 | Electrodes spacing: Score 4 | Electrodes spacing: Score 5 | Electrodes spacing: Score 6 | Electrodes spacing: Score 7 | Electrode array coverage: Score 1 | Electrode array coverage: Score 2 | Electrode array coverage: Score 3 | Electrode array coverage: Score 4 | Electrode array coverage: Score 5 | Electrode array coverage: Score 6 | Electrode array coverage: Score 7 | |
| OPTRELL Mapping Catheter | 0 | 1 | 0 | 2 | 2 | 18 | 8 | 0 | 1 | 0 | 0 | 0 | 13 | 17 | 0 | 1 | 0 | 0 | 0 | 9 | 21 |
Number of responders for physician assessment for catheter visualization were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for catheter visualization. (NCT04983797)
Timeframe: Up to 72 days
| Intervention | Participants (Count of Participants) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Visualization under fluoroscopy: Score 1 | Visualization under fluoroscopy: Score 2 | Visualization under fluoroscopy: Score 3 | Visualization under fluoroscopy: Score 4 | Visualization under fluoroscopy: Score 5 | Visualization under fluoroscopy: Score 6 | Visualization under fluoroscopy: Score 7 | Visualization in CARTO 3: Score 1 | Visualization in CARTO 3: Score 2 | Visualization in CARTO 3: Score 3 | Visualization in CARTO 3: Score 4 | Visualization in CARTO 3: Score 5 | Visualization in CARTO 3: Score 6 | Visualization in CARTO 3: Score 7 | |
| OPTRELL Mapping Catheter | 0 | 0 | 0 | 0 | 7 | 9 | 15 | 0 | 0 | 0 | 0 | 3 | 10 | 18 |
Number of responders for physician assessment for catheters interactions were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for catheters interactions. (NCT04983797)
Timeframe: Up to 72 days
| Intervention | Participants (Count of Participants) | ||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| With CARTO 3 System: Score 1 | With CARTO 3 System: Score 2 | With CARTO 3 System: Score 3 | With CARTO 3 System: Score 4 | With CARTO 3 System: Score 5 | With CARTO 3 System: Score 6 | With CARTO 3 System: Score 7 | EP Lab recording equipment: Score 1 | EP Lab recording equipment: Score 2 | EP Lab recording equipment: Score 3 | EP Lab recording equipment: Score 4 | EP Lab recording equipment: Score 5 | EP Lab recording equipment: Score 6 | EP Lab recording equipment: Score 7 | Pacing equipment: Score 1 | Pacing equipment: Score 2 | Pacing equipment: Score 3 | Pacing equipment: Score 4 | Pacing equipment: Score 5 | Pacing equipment: Score 6 | Pacing equipment: Score 7 | Introducer tool on catheter: Score 1 | Introducer tool on catheter: Score 2 | Introducer tool on catheter: Score 3 | Introducer tool on catheter: Score 4 | Introducer tool on catheter: Score 5 | Introducer tool on catheter: Score 6 | Introducer tool on catheter: Score 7 | Sheath: Score 1 | Sheath: Score 2 | Sheath: Score 3 | Sheath: Score 4 | Sheath: Score 5 | Sheath: Score 6 | Sheath: Score 7 | Irrigation bag and tubing: Score 1 | Irrigation bag and tubing: Score 2 | Irrigation bag and tubing: Score 3 | Irrigation bag and tubing: Score 4 | Irrigation bag and tubing: Score 5 | Irrigation bag and tubing: Score 6 | Irrigation bag and tubing: Score 7 | ICD or other implantable devices: Score 1 | ICD or other implantable devices: Score 2 | ICD or other implantable devices: Score 3 | ICD or other implantable devices: Score 4 | ICD or other implantable devices: Score 5 | ICD or other implantable devices: Score 6 | ICD or other implantable devices: Score 7 | |
| OPTRELL Mapping Catheter | 0 | 0 | 0 | 0 | 4 | 12 | 15 | 0 | 0 | 0 | 1 | 8 | 12 | 10 | 0 | 0 | 0 | 0 | 4 | 3 | 7 | 0 | 0 | 0 | 3 | 6 | 14 | 8 | 0 | 0 | 0 | 3 | 6 | 14 | 8 | 0 | 0 | 0 | 0 | 5 | 15 | 11 | 0 | 0 | 0 | 1 | 2 | 2 | 3 |
Number of responders for physician assessment for design and coverage for confirming PVI were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for design and coverage for confirming PVI. (NCT04983797)
Timeframe: Up to 72 days
| Intervention | Participants (Count of Participants) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compared to the PENTARAY catheter?: Score 1 | Compared to the PENTARAY catheter?: Score 2 | Compared to the PENTARAY catheter?: Score 3 | Compared to the PENTARAY catheter?: Score 4 | Compared to the PENTARAY catheter?: Score 5 | Compared to the PENTARAY catheter?: Score 6 | Compared to the PENTARAY catheter?: Score 7 | Compared to other competitive multielectrode catheters?: Score 1 | Compared to other competitive multielectrode catheters?: Score 2 | Compared to other competitive multielectrode catheters?: Score 3 | Compared to other competitive multielectrode catheters?: Score 4 | Compared to other competitive multielectrode catheters?: Score 5 | Compared to other competitive multielectrode catheters?: Score 6 | Compared to other competitive multielectrode catheters?: Score 7 | |
| OPTRELL Mapping Catheter | 0 | 0 | 0 | 3 | 2 | 7 | 9 | 0 | 0 | 0 | 4 | 0 | 13 | 4 |
Number of responders for physician assessment for maneuverability & handling were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for maneuverability & handling. (NCT04983797)
Timeframe: Up to 72 days
| Intervention | Participants (Count of Participants) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ability to Deploy (Left Atrium): Score 1 | Ability to Deploy (Left Atrium): Score 2 | Ability to Deploy (Left Atrium): Score 3 | Ability to Deploy (Left Atrium): Score 4 | Ability to Deploy (Left Atrium): Score 5 | Ability to Deploy (Left Atrium): Score 6 | Ability to Deploy (Left Atrium): Score 7 | Ability to Deploy (Right Atrium): Score 1 | Ability to Deploy (Right Atrium): Score 2 | Ability to Deploy (Right Atrium): Score 3 | Ability to Deploy (Right Atrium): Score 4 | Ability to Deploy (Right Atrium): Score 5 | Ability to Deploy (Right Atrium): Score 6 | Ability to Deploy (Right Atrium): Score 7 | Ability to Deploy (Left Ventricle): Score 1 | Ability to Deploy (Left Ventricle): Score 2 | Ability to Deploy (Left Ventricle): Score 3 | Ability to Deploy (Left Ventricle): Score 4 | Ability to Deploy (Left Ventricle): Score 5 | Ability to Deploy (Left Ventricle): Score 6 | Ability to Deploy (Left Ventricle): Score 7 | Ability to Deploy (Right Ventricle): Score 1 | Ability to Deploy (Right Ventricle): Score 2 | Ability to Deploy (Right Ventricle): Score 3 | Ability to Deploy (Right Ventricle): Score 4 | Ability to Deploy (Right Ventricle): Score 5 | Ability to Deploy (Right Ventricle): Score 6 | Ability to Deploy (Right Ventricle): Score 7 | Ability to Maneuver (Left Atrium): Score 1 | Ability to Maneuver (Left Atrium): Score 2 | Ability to Maneuver (Left Atrium): Score 3 | Ability to Maneuver (Left Atrium): Score 4 | Ability to Maneuver (Left Atrium): Score 5 | Ability to Maneuver (Left Atrium): Score 6 | Ability to Maneuver (Left Atrium): Score 7 | Ability to Maneuver (Right Atrium): Score 1 | Ability to Maneuver (Right Atrium): Score 2 | Ability to Maneuver (Right Atrium): Score 3 | Ability to Maneuver (Right Atrium): Score 4 | Ability to Maneuver (Right Atrium): Score 5 | Ability to Maneuver (Right Atrium): Score 6 | Ability to Maneuver (Right Atrium): Score 7 | Ability to Maneuver (Left Ventricle): Score 1 | Ability to Maneuver (Left Ventricle): Score 2 | Ability to Maneuver (Left Ventricle): Score 3 | Ability to Maneuver (Left Ventricle): Score 4 | Ability to Maneuver (Left Ventricle): Score 5 | Ability to Maneuver (Left Ventricle): Score 6 | Ability to Maneuver (Left Ventricle): Score 7 | Ability to Maneuver (Right Ventricle): Score 1 | Ability to Maneuver (Right Ventricle): Score 2 | Ability to Maneuver (Right Ventricle): Score 3 | Ability to Maneuver (Right Ventricle): Score 4 | Ability to Maneuver (Right Ventricles): Score 5 | Ability to Maneuver (Right Ventricle): Score 6 | Ability to Maneuver (Right Ventricle): Score 7 | Ability to Reach Areas (Left Atrium): Score 1 | Ability to Reach Areas (Left Atrium): Score 2 | Ability to Reach Areas (Left Atrium): Score 3 | Ability to Reach Areas (Left Atrium): Score 4 | Ability to Reach Areas (Left Atrium): Score 5 | Ability to Reach Areas (Left Atrium): Score 6 | Ability to Reach Areas (Left Atrium): Score 7 | Ability to Reach Areas (Right Atrium): Score 1 | Ability to Reach Areas (Right Atrium): Score 2 | Ability to Reach Areas (Right Atrium): Score 3 | Ability to Reach Areas (Right Atrium): Score 4 | Ability to Reach Areas (Right Atrium): Score 5 | Ability to Reach Areas (Right Atrium): Score 6 | Ability to Reach Areas (Right Atrium): Score 7 | Ability to Reach Areas (Left Ventricle): Score 1 | Ability to Reach Areas (Left Ventricle): Score 2 | Ability to Reach Areas (Left Ventricle): Score 3 | Ability to Reach Areas (Left Ventricle): Score 4 | Ability to Reach Areas (Left Ventricle): Score 5 | Ability to Reach Areas (Left Ventricle): Score 6 | Ability to Reach Areas (Left Ventricle): Score 7 | Ability to Reach Areas (Right Ventricle): Score 1 | Ability to Reach Areas (Right Ventricle): Score 2 | Ability to Reach Areas (Right Ventricle): Score 3 | Ability to Reach Areas (Right Ventricle): Score 4 | Ability to Reach Areas (Right Ventricle): Score 5 | Ability to Reach Areas (Right Ventricle): Score 6 | Ability to Reach Areas (Right Ventricle): Score 7 | Ability to Withdraw (Left Atrium): Score 1 | Ability to Withdraw (Left Atrium): Score 2 | Ability to Withdraw (Left Atrium): Score 3 | Ability to Withdraw (Left Atrium): Score 4 | Ability to Withdraw (Left Atrium): Score 5 | Ability to Withdraw (Left Atrium): Score 6 | Ability to Withdraw (Left Atrium): Score 7 | Ability to Withdraw (Right Atrium): Score 1 | Ability to Withdraw (Right Atrium): Score 2 | Ability to Withdraw (Right Atrium): Score 3 | Ability to Withdraw (Right Atrium): Score 4 | Ability to Withdraw (Right Atrium): Score 5 | Ability to Withdraw (Right Atrium): Score 6 | Ability to Withdraw (Right Atrium): Score 7 | Ability to Withdraw (Left Ventricle): Score 1 | Ability to Withdraw (Left Ventricle): Score 2 | Ability to Withdraw (Left Ventricle): Score 3 | Ability to Withdraw (Left Ventricle): Score 4 | Ability to Withdraw (Left Ventricle): Score 5 | Ability to Withdraw (Left Ventricle): Score 6 | Ability to Withdraw (Left Ventricle): Score 7 | Ability to Withdraw (Right Ventricle): Score 1 | Ability to Withdraw (Right Ventricle): Score 2 | Ability to Withdraw (Right Ventricle): Score 3 | Ability to Withdraw (Right Ventricle): Score 4 | Ability to Withdraw (Right Ventricle): Score 5 | Ability to Withdraw (Right Ventricle): Score 6 | Ability to Withdraw (Right Ventricle): Score 7 | Insertion/ Withdrawal from Introducer Sheath: Score 1 | Insertion/ Withdrawal from Introducer Sheath: Score 2 | Insertion/ Withdrawal from Introducer Sheath: Score 3 | Insertion/ Withdrawal from Introducer Sheath: Score 4 | Insertion/ Withdrawal from Introducer Sheath: Score 5 | Insertion/ Withdrawal from Introducer Sheath: Score 6 | Insertion/ Withdrawal from Introducer Sheath: Score 7 | Learning Curve: Score 1 | Learning Curve: Score 2 | Learning Curve: Score 3 | Learning Curve: Score 4 | Learning Curve: Score 5 | Learning Curve: Score 6 | Learning Curve: Score 7 | |
| OPTRELL Mapping Catheter | 0 | 0 | 0 | 0 | 0 | 6 | 17 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 0 | 0 | 0 | 3 | 1 | 5 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 7 | 9 | 0 | 0 | 0 | 0 | 1 | 1 | 4 | 0 | 0 | 0 | 5 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 12 | 6 | 0 | 0 | 0 | 0 | 2 | 1 | 3 | 0 | 0 | 1 | 3 | 2 | 3 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 15 | 0 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 0 | 0 | 2 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 9 | 9 | 10 | 0 | 0 | 0 | 4 | 4 | 18 | 5 |
Number of responders for physician assessment for pacing (local pacing capture) were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for pacing. (NCT04983797)
Timeframe: Up to 72 days
| Intervention | Participants (Count of Participants) | ||||||
|---|---|---|---|---|---|---|---|
| Local pacing capture: Score 1 | Local pacing capture: Score 2 | Local pacing capture: Score 3 | Local pacing capture: Score 4 | Local pacing capture: Score 5 | Local pacing capture: Score 6 | Local pacing capture: Score 7 | |
| OPTRELL Mapping Catheter | 0 | 0 | 1 | 1 | 2 | 2 | 3 |
Number of responders for physician assessment for signal collection and quality were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for signal collection and quality (NCT04983797)
Timeframe: Up to 72 days
| Intervention | Participants (Count of Participants) | |||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UNIPOLAR signals in Atrium: Score 1 | UNIPOLAR signals in Atrium: Score 2 | UNIPOLAR signals in Atrium: Score 3 | UNIPOLAR signals in Atrium: Score 4 | UNIPOLAR signals in Atrium: Score 5 | UNIPOLAR signals in Atrium: Score 6 | UNIPOLAR signals in Atrium: Score 7 | UNIPOLAR signals in Ventricle: Score 1 | UNIPOLAR signals in Ventricle: Score 2 | UNIPOLAR signals in Ventricle: Score 3 | UNIPOLAR signals in Ventricle: Score 4 | UNIPOLAR signals in Ventricle: Score 5 | UNIPOLAR signals in Ventricle: Score 6 | UNIPOLAR signals in Ventricle: Score 7 | UNIPOLAR noise encountered: Score 1 | UNIPOLAR noise encountered: Score 2 | UNIPOLAR noise encountered: Score 3 | UNIPOLAR noise encountered: Score 4 | UNIPOLAR noise encountered: Score 5 | UNIPOLAR noise encountered: Score 6 | UNIPOLAR noise encountered: Score 7 | BIPOLAR signals in Atrium: Score 1 | BIPOLAR signals in Atrium: Score 2 | BIPOLAR signals in Atrium: Score 3 | BIPOLAR signals in Atrium: Score 4 | BIPOLAR signals in Atrium: Score 5 | BIPOLAR signals in Atrium: Score 6 | BIPOLAR signals in Atrium: Score 7 | BIPOLAR signals in Ventricle: Score 1 | BIPOLAR signals in Ventricle: Score 2 | BIPOLAR signals in Ventricle: Score 3 | BIPOLAR signals in Ventricle: Score 4 | BIPOLAR signals in Ventricle: Score 5 | BIPOLAR signals in Ventricle: Score 6 | BIPOLAR signals in Ventricle: Score 7 | BIPOLAR noise encountered: Score 1 | BIPOLAR noise encountered: Score 2 | BIPOLAR noise encountered: Score 3 | BIPOLAR noise encountered: Score 4 | BIPOLAR noise encountered: Score 5 | BIPOLAR noise encountered: Score 6 | BIPOLAR noise encountered: Score 7 | |
| OPTRELL Mapping Catheter | 0 | 0 | 0 | 0 | 1 | 4 | 2 | 0 | 0 | 0 | 1 | 3 | 4 | 0 | 0 | 0 | 0 | 1 | 4 | 7 | 4 | 0 | 0 | 0 | 0 | 0 | 7 | 16 | 0 | 0 | 0 | 0 | 1 | 7 | 1 | 0 | 0 | 0 | 1 | 3 | 12 | 15 |
Number of responders for physician assessment for workflow were reported. A post-procedure survey of 11 questions, each with individual sub-questions were asked. Each question/sub-question was answered by the physician using a Likert scale of 1 to 7 (1=poor and 7=excellent). Responders refers to participants with physician assessment for workflow. (NCT04983797)
Timeframe: Up to 72 days
| Intervention | Participants (Count of Participants) | |||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ability to reduce fluoroscopy: Score 1 | Ability to reduce fluoroscopy: Score 2 | Ability to reduce fluoroscopy: Score 3 | Ability to reduce fluoroscopy: Score 4 | Ability to reduce fluoroscopy: Score 5 | Ability to reduce fluoroscopy: Score 6 | Ability to reduce fluoroscopy: Score 7 | Time for pre-procedure mapping: Score 1 | Time for pre-procedure mapping: Score 2 | Time for pre-procedure mapping: Score 3 | Time for pre-procedure mapping: Score 4 | Time for pre-procedure mapping: Score 5 | Time for pre-procedure mapping: Score 6 | Time for pre-procedure mapping: Score 7 | Time for post-procedure mapping after standard of care ablation: Score 1 | Time for post-procedure mapping after standard of care ablation: Score 2 | Time for post-procedure mapping after standard of care ablation: Score 3 | Time for post-procedure mapping after standard of care ablation: Score 4 | Time for post-procedure mapping after standard of care ablation: Score 5 | Time for post-procedure mapping after standard of care ablation: Score 6 | Time for post-procedure mapping after standard of care ablation: Score 7 | Ability to identify targets: Score 1 | Ability to identify targets: Score 2 | Ability to identify targets: Score 3 | Ability to identify targets: Score 4 | Ability to identify targets: Score 5 | Ability to identify targets: Score 6 | Ability to identify targets: Score 7 | |
| OPTRELL Mapping Catheter | 0 | 0 | 0 | 10 | 6 | 10 | 5 | 0 | 0 | 0 | 8 | 4 | 10 | 9 | 0 | 0 | 0 | 2 | 4 | 9 | 9 | 0 | 0 | 0 | 1 | 0 | 13 | 14 |
3 reviews available for bupivacaine and Drug Hypersensitivity
| Article | Year |
|---|---|
Local anesthesia: advances in agents and techniques.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Carticaine; Chemistry, Pharm | 2002 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Eti | 2003 |
Physiology and pharmacology of local anesthetic agents.
Topics: Administration, Topical; Amides; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Ce | 1973 |
28 other studies available for bupivacaine and Drug Hypersensitivity
| Article | Year |
|---|---|
[Intrathecal bupivacaine and allergic reaction].
Topics: Anesthetics, Local; Bupivacaine; Diagnosis, Differential; Drug Hypersensitivity; Humans; Injections, | 2015 |
Hyaluronidase hypersensitivity: A rare complication of peribulbar block.
Topics: Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Cataract Extraction; Drug Hypersensitivity; | 2016 |
Delayed urticaria due to bupivacaine: A new presentation of local anesthetic allergy.
Topics: Anesthetics, Local; Bupivacaine; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; M | 2016 |
Progressively Worsening Hypersensitivity Reaction to Bupivacaine.
Topics: Aged; Anesthetics, Local; Bupivacaine; Diagnosis, Differential; Disease Progression; Drug Hypersensi | 2017 |
RETRACTED: Perioperative analgesia for carotid endarterectomy in NSAIDs allergy.
Topics: Analgesia, Patient-Controlled; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Local; Ant | 2017 |
[Immunoallergic transitory paraplegia after regional anaesthesia].
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Anti-Inflammatory Agents; Botulinum Toxins, Type A; B | 2009 |
Severe adverse reactions to dental local anaesthetics: systemic reactions.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anesthesia, Den | 2011 |
Anaphylaxis secondary to levobupivacaine.
Topics: Adult; Anaphylaxis; Anesthesia, General; Anesthetics, Local; Bupivacaine; Decompression, Surgical; D | 2011 |
Fatality involving complications of bupivacaine toxicity and hypersensitivity reaction.
Topics: Adult; Anesthetics, Local; Atrial Septum; Bradycardia; Bupivacaine; Cardiomegaly; Drug Hypersensitiv | 2011 |
Commentary on: Dudley MH, Fleming SW, Garg U, Edwards JM. Fatality involving complications of bupivacaine toxicity and hypersensitivity reaction. J Forensic Sci 2011;56(5):1376-9.
Topics: Anesthetics, Local; Bupivacaine; Drug Hypersensitivity; Heart Arrest; Humans; Male | 2012 |
Commentary on: Dudley MH, Fleming SW, Garg U, Edwards JM. Fatality involving complications of bupivacaine toxicity and hypersensitivity reaction. J Forensic Sci 2011;56(5):1376-9.
Topics: Anesthetics, Local; Bupivacaine; Drug Hypersensitivity; Heart Arrest; Humans; Male | 2012 |
Immediate allergic cross-reactivity to levobupivacaine and ropivacaine.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Aged; Amides; Anaphylaxis; Anesthesia, Conduction; Ane | 2013 |
IgE-mediated reaction to local anaesthetics.
Topics: Adult; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Cesarean Section; Drug Hypersensitivit | 2013 |
Local anesthetic allergy in a parturient.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Sectio | 2003 |
Evaluation of adverse reactions to local anesthetics: experience with 236 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Child; Child, Preschool | 2003 |
Hyaluronidase allergy after peribulbar anesthesia with orbital inflammation.
Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Bupivacaine; Cellulitis; Drug Hypersensitivity; Fema | 2004 |
Hyaluronidase allergy after peribulbar anesthesia with orbital inflammation.
Topics: Anesthesia, Local; Anesthetics, Combined; Bupivacaine; Cellulitis; Drug Hypersensitivity; Glucocorti | 2005 |
[Toxic and allergic reactions to local anesthetics].
Topics: Bupivacaine; Drug Hypersensitivity; Humans; Lidocaine; Procaine | 1984 |
Allergic reaction to an amide local anaesthetic.
Topics: Aged; Bupivacaine; Complement C4; Drug Hypersensitivity; Female; Humans; Intradermal Tests | 1981 |
Allergic reaction to an amide local anaesthetic.
Topics: Anesthetics, Local; Bupivacaine; Drug Hypersensitivity; Humans; Parabens | 1981 |
[Anesthesia in a patient with history of multiple drug allergies].
Topics: Adult; Anaphylaxis; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Bupivacaine | 1995 |
Adverse reaction to bupivacaine.
Topics: Aged; Anesthetics, Local; Bupivacaine; Drug Hypersensitivity; Female; Humans; Skin Tests | 1996 |
Dyclonine hydrochloride for airway anesthesia: awake endotracheal intubation in a patient with suspected local anesthetic allergy.
Topics: Adult; Anesthetics, Local; Bupivacaine; Drug Hypersensitivity; Female; Humans; Intubation, Intratrac | 1997 |
Cardiac catheterization in the patient with history of allergy to local anesthetics.
Topics: Adult; Anesthetics, Local; Bupivacaine; Cardiac Catheterization; Catheterization; Drug Hypersensitiv | 1990 |
A mistaken case of hypersensitivity to a local anaesthetic.
Topics: Adult; Anesthesia, Obstetrical; Animals; Animals, Domestic; Bupivacaine; Diagnosis, Differential; Do | 1986 |
Anaphylactic reaction to lidocaine.
Topics: Adult; Anaphylaxis; Bupivacaine; Drug Evaluation; Drug Hypersensitivity; Female; Humans; Intradermal | 1986 |
[Complications of regional anaesthesia and their treatment (author's transl)].
Topics: Adrenal Cortex Hormones; Anesthesia, Local; Apnea; Barbiturates; Bradycardia; Bupivacaine; Diagnosis | 1973 |
[Contraindications and complications of regional anaesthesia].
Topics: Abscess; Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, Intravenous; Anesthesia, Spinal; | 1972 |