bupivacaine has been researched along with Disease Models, Animal in 114 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (7.02) | 18.2507 |
| 2000's | 33 (28.95) | 29.6817 |
| 2010's | 64 (56.14) | 24.3611 |
| 2020's | 9 (7.89) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, Y; Chen, H; Jin, Z; Liu, L; Papadimos, TJ; Shi, K; Wang, Q; Xia, E; Xia, F; Xia, Y; Xu, X; Ye, Y | 1 |
| Almendral, J; Anadón, MJ; Fernández, I; García, S; Quintela, O; Rodríguez, L; Varela, O; Zaballos, M | 1 |
| Carré, D; Castel, D; Cornet, S; Evans, S; Horne, R; Kalinichev, M; Lezmi, S; Limana, L; Meilin, S; Pons, L | 1 |
| Andrews, NA; Bean, BP; Heckman, LM; Jacquemont, T; Jain, A; Jo, S; Kotoda, M; Lee, J; Lee, S; Liu, PW; Pascal, M; Puopolo, M; Talbot, S; Woolf, CJ; Zhang, HB | 1 |
| Ancelin, D; Bennis, M; Brouchet, A; Cavaignac, E; Charre, A; Dray, C; Ferré, F; Krin, A; Kurrek, M; Marty, P; Minville, V; Sanchez, M | 1 |
| Ji, Z; Liu, Z; Xia, Z; Xu, H; Xu, R; Xu, S; Zhao, W | 1 |
| Liang, C; Shengkai, G; Tenghuan, W; Yuning, F; Zhenhua, N | 1 |
| Furer, A; Giladi, S; Goder, D; Zilberman, M | 1 |
| Kang, H; Oh, SS; Park, JS; Yoo, H | 1 |
| Ben Rehouma, M; Benhamou, D; Bouchouareb, M; Hamdi, L; Kfoury, T; Mazoit, JX; Soued, M | 1 |
| Fettiplace, MR; McCabe, DJ | 1 |
| Ayoğlu, H; Pişkin, Ö | 1 |
| Chan, SM; Chou, YT; Chuang, WT; Lin, BF; Wong, CS; Wu, ZF | 1 |
| Horiguchi, T; Kimura, T; Nishikawa, T; Yoshimoto, M | 1 |
| Cao, J; Chen, L; Chen, M; Huang, W; Wang, M; Wang, X; Ying, T | 1 |
| Godbout, JP; Humeidan, M; Jarrett, BL; Kim, JK; Sawicki, CM; Sheridan, JF; Weber, MD | 1 |
| Dai, F; Hurwitz, O; LaMotte, RH; Ma, C; Shimada, SG; Tian, D; Wang, T; Zhou, J | 1 |
| Cooke, MB; Hayes, A; Rybalka, E; Stathis, CG | 1 |
| Eskandari, M; Sarchahi, AA | 1 |
| Cai, X; Jin, Z; Liu, L; Papadimos, TJ; Shi, K; Xia, Y; Xu, X; Zhang, M | 1 |
| Chen, Y; Cheng, Y; Chu, L; Duan, R; Li, H; Li, J; Xia, D; Yuan, J; Zhang, J; Zhang, Y; Zhao, S; Zhao, X | 1 |
| Karimi, A; Moradkhani, MR | 1 |
| Cvetko, E; Damjanovska, M; Hadzic, A; Kuroda, MM; Sega Jazbec, S; Seliskar, A; Stopar Pintaric, T; Zel, J | 1 |
| Choi, SH; Kim, JM | 1 |
| Iwasaki, K; Iwasaki, N; Sudo, H; Tsujimoto, T; Ukeba, D; Ura, K | 1 |
| Almendral, J; Anadón Baselga, MJ; Callejo, D; López-Menchaca, R; Melone, A; Quintela, O; Sevilla, R; Varela, O; Zaballos, M | 1 |
| Kang, BC; Kim, CM; Kim, CS; Kim, MH; Lee, KH; Uugangerel, T; Yang, S | 1 |
| Chen, TY; Chen, YC; Chen, YW; Hung, CH; Tzeng, JI; Wang, JJ | 1 |
| Domb, AJ; Golovanevski, L; Haze, A; Ickowicz, DE; Weiniger, CF | 1 |
| Hanouz, JL; Lemoine, S; Manrique, A; Rouet, R | 1 |
| Ayrizono, Mde L; Camargo, MG; Chung, WF; Coy, CS; Fagundes, JJ; Leal, RF; Lee, HD; Oliveira, Pde S; Rossi, DH | 1 |
| Akpa, BS; Fettiplace, MR; Lang, J; Ripper, R; Rubinstein, I; Weinberg, G; Zider, B | 1 |
| Domb, AJ; Golovanevski, L; Ickowicz, DE; Weiniger, CF | 1 |
| Colmena, I; de Pascual, R; Gandía, L; Lagrota-Candido, J; Leite, PE; Nanclares, C; Quirico-Santos, T; Santos, WC | 1 |
| Diaz, JA; Hawley, AE; Hish, GA; Lester, PA; Myers, DD | 1 |
| Aydin, S; Aydoğan, A; Davarci, I; Karcioğlu, M; Özden, R; Sari, A; Sefil, F; Tuzcu, K | 1 |
| An, K; Elkassabany, NM; Liu, J | 1 |
| Ogata, T; Ohira, Y; Oishi, Y; Roy, RR | 1 |
| Eghbali, M; Li, J; Partownavid, P; Rahman, S; Sharma, S; Umar, S | 1 |
| Russell, G; Strichartz, GR; Wang, CF; Wang, GK | 1 |
| Bui-Xuan, B; Chevalier, P; Descotes, J; Mamou, Z; Romestaing, C; Timour, Q | 1 |
| Brennan, TJ; Dalm, BD; Howard, MA; Kang, S; Reddy, CG | 1 |
| Bonini, M; Fettiplace, MR; Kowal, K; Lis, K; Minshall, R; Ripper, R; Rubinstein, I; Weinberg, G; Young, A | 1 |
| Chun, K; Hahm, SC; Kim, EH; Kim, J; Kim, T; Ko, C; Lim, TH; Seol, DR | 1 |
| Alizadeh, L; Arhami-Dolatabadi, A; Daneshbod, Y; Hosseinian, MA; Khandaghy, M; Memari, E; Mirabotalebi, M; Mirkheshti, A; Shirian, S | 1 |
| Gao, JL; Han, FF; Li, XX; Li, YL; Wang, XM; Zhang, DH; Zhang, HJ; Zhao, QL | 1 |
| Byram, SC; Byram, SW; Fargo, KN; Miller, NM | 1 |
| Campos, CR; Davis, TP; Egleton, RD; Hom, S; Ocheltree, SM | 1 |
| Di Gregorio, G; Feinstein, DL; Kelly, K; Massad, M; Minshall, RD; Ori, C; Ripper, R; Schwartz, D; Weinberg, GL | 1 |
| Strong, JA; Xie, W; Zhang, JM | 1 |
| Aritake, K; Kamauchi, S; Maruyama, T; Mohri, I; Nagata, N; Sato, Y; Taniguchi, H; Taniike, M; Urade, Y | 1 |
| Noyan, N; Sahin, C; Sen, H; Uygur, F | 1 |
| Callaway, CW; Empey, PE; Hicks, SD; Logue, ES; Menegazzi, JJ; Miller, DR; Poloyac, SM; Salcido, DD; Suffoletto, BP | 1 |
| Brennan, TJ; Xu, J | 1 |
| Cave, G; Harvey, MG; Winterbottom, T | 1 |
| Demir, MN; Demir, ZA; Nurözler, AB; Ornek, F; Yalçin Tök, O; Yilmaz, FM; Yilmaz, G | 1 |
| Bettschart-Wolfensberger, R; Frotzler, A; Koepfer, N; Kutter, AP; Madjdpour, C; Mauch, J; Weiss, M | 1 |
| Betto, R; Danieli-Betto, D; Franzoso, S; Germinario, E; Peron, S; Sandonà, D; Sorci, G; Zanin, M | 1 |
| El-Orbany, M; Woehlck, HJ | 1 |
| Beloeil, H; Benhamou, D; Combettes, E; Deruddre, S; Duranteau, J; Estebe, JP; Mazoit, JX | 1 |
| Ashcroft, GS; Gilliver, SC; Hardman, MJ; Masterson, GR; Waite, A | 1 |
| Aker, S; Duman, U; Ozturk, E; Sarandol, E; Yilmazlar, A; Yilmazlar, T | 1 |
| Cave, G; Desmet, J; Harvey, M; Lahner, D; Prince, G | 1 |
| Beloeil, H; Benhamou, D; Combettes, E; Mazoit, JX | 1 |
| Cetin, C; Karabaggli, Y; Kiremitci, A; Kocman, E; Kose, AA | 1 |
| Guyton, DL; Phamonvaechavan, P; Poon, DY; Rajan, A; Topcu-Yilmaz, P; Zhang, C | 1 |
| Mather, LE | 1 |
| del Valle, J; Domenech, J; Escribano, E; Garcia, X; Queralt, J | 1 |
| Akpa, BS; Bern, S; Kuo, I; Weinberg, G | 1 |
| Athiraman, U; Berde, CB; Carpino, EA; Corfas, G; Soriano, SG; Yahalom, B; Zurakowski, D | 1 |
| Butterworth, JF; Wolfe, JW | 1 |
| Brubaker, AN; Cole, PI; Haan, D; Nelson, KG; Newton, PE; Ott, LR; Rebelatto, MC; Richard, BM; Ross, PE | 1 |
| Abdalla, RJ; Beutel, A; Cohen, M; de Castro Pochini, A; Ferreira, AM; Garcia Lisboa, BC; Han, SW; McNeill Ingham, SJ; Oliveira, DA; Valero-Lapchik, VB | 1 |
| Gunay, I; Gunes, Y; Mert, T | 1 |
| Chen, H; Ding, X; Dong, H; Dong, X; Jin, Z; Li, Z; Papadimos, TJ; Wang, X; Xia, F; Xia, Y; Xu, X | 1 |
| Cunningham, CL; Groblewski, PA | 1 |
| Hu, Z; Li, B; Ma, Z; Shen, Y; Yan, J | 1 |
| Cao, F; Fang, Y; Gu, Y; Tang, Y; Wang, L; Wang, X | 1 |
| Abrão, J; Bachur, JA; Fernandes, CR; Garcia, SB; Lima, GB; Okubo, R; Shimano, AC; White, PF | 1 |
| Chun-jing, H; Guo-dong, L; Hao-xiong, N; Shan, O; Ya-ping, F; Yi-ran, L | 1 |
| Dabezies, EJ; Graham, S; Henry, BJ; Kenison, M; McVay, C; Rasty, J; Rolfe, R; Slauterbeck, J | 1 |
| Ishii, M; Kaneda, K; Kiyama, H; Maeda, M; Muraoka, M; Ohba, N; Sakamoto, H | 1 |
| Bacher, JD; Banks, SM; Costello, R; Csako, G; Danner, RL; Eichacker, PQ; Gerstenberger, E; Natanson, C; Solomon, SB; Thomas, ML | 1 |
| Del Bel, EA; Prado, WA; Villarreal, CF | 1 |
| Bonney, I; Carr, DB; Goudas, LC; Hasirci, V; Shuster, L; Wise, DL | 1 |
| Bernard, N; Capdevila, X; Lopez, S; Ohanna, F; Privat, A; Vergnes, C | 1 |
| Ecoffey, C; Estebe, JP; Gentili, ME; Le Corre, P; Leduc, C; Moulinoux, JP | 1 |
| Chevalier, E; Chovet, M; Langlois, A; Pétoux, F | 1 |
| Meij, JTA; Strong, JA; Xie, W; Yu, L; Zhang, JM | 1 |
| Lauritzen, B; Lykkegaard, K; Svendsen, O; Tessem, L; Weikop, P | 1 |
| Colarossi, FE; Lynch, GS; Plant, DR | 1 |
| Bach, BR; Cole, BJ; Gomoll, AH; Kang, RW; Williams, JM | 1 |
| Basu, S; Eriksson, MB; Gustafsson, U; Larsson, AO; Mutschler, DK | 1 |
| Bai, ZT; Chai, ZF; Ji, YH; Liu, T; Pang, XY | 1 |
| Weinberg, G | 1 |
| Berde, CB; Decosterd, I; Huang, J; Ji, RR; Kawasaki, Y; Kohno, T; Pertin, M; Suter, MR; Wen, YR | 1 |
| Reider, B | 1 |
| Panni, JK; Panni, MK | 1 |
| Gritsch, C; Lindner, KH; Luckner, G; Mayr, VD; Mitterschiffthaler, L; Müller, T; Neurauter, A; Strohmenger, HU; Wenzel, V | 1 |
| Di Gregorio, G; Edelman, L; Feinstein, DL; Kelly, K; Massad, M; Ripper, R; Schwartz, D; Shah, N; Weinberg, GL; Zheng, S | 1 |
| Mizuguchi, K; Yamamoto, T | 1 |
| Andersson, KE; Igawa, Y; Mattiasson, A; Post, C; Uvelius, B | 1 |
| Frame, WB; Lim, HJ; Mergner, GW; Stolte, AL | 1 |
| Kou, YR; Lee, TY; Tang, GJ; Yuan, HB | 1 |
| Adsan, H; Onaran, O; Tulunay, M | 1 |
| Gebhart, GF; Hayashi, N; Lee, HM; Meller, ST; Spratt, KF; Weinstein, JN | 1 |
| Caramutti, D; Justo, JR; Mele, E; Pirágine, M | 1 |
| Johnson, ME | 1 |
| Abdi, S; Chung, JM; Lee, DH; Park, SK | 1 |
| Fiszman, M; Hagège, AA; Menasché, P; Messas, E; Pouzet, B; Schwartz, K; Scorsin, M; Vilquin, JT | 1 |
| Chang, DH; Mather, LE | 1 |
| Anurov, M; Fass, J; Jansen, M; Mumme, T; Ottinger, A; Polivoda, M; Schumpelick, V; Titkova, S; Tittel, A | 1 |
| Luz, MA; Marques, MJ; Santo Neto, H | 1 |
| Hayes, RL; Lu, J; Mao, J; Mayer, DJ; Price, DD | 1 |
7 review(s) available for bupivacaine and Disease Models, Animal
| Article | Year |
|---|---|
Lipid emulsion improves survival in animal models of local anesthetic toxicity: a meta-analysis.
Topics: Anesthetics, Local; Animals; Bupivacaine; Combined Modality Therapy; Disease Models, Animal; Dogs; Drug Compounding; Emulsions; Fat Emulsions, Intravenous; Odds Ratio; Poisoning; Rabbits; Rats; Resuscitation; Risk Assessment; Risk Factors; Swine; Time Factors | 2017 |
The acute toxicity of local anesthetics.
Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Central Nervous System Diseases; Disease Models, Animal; Humans; Levobupivacaine; Ropivacaine; Toxicity Tests, Acute | 2010 |
Lipid resuscitation: a life-saving antidote for local anesthetic toxicity.
Topics: Anesthesia, Conduction; Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Fat Emulsions, Intravenous; Female; Heart Arrest; Humans; Male; Rats | 2011 |
Local anesthetic systemic toxicity: update on mechanisms and treatment.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Cardiovascular Diseases; Disease Models, Animal; Epinephrine; Fat Emulsions, Intravenous; Humans; Lidocaine; Neurotoxicity Syndromes; Vasoconstrictor Agents; Vasopressins | 2011 |
Lipid rescue resuscitation from local anaesthetic cardiac toxicity.
Topics: Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Etidocaine; Fat Emulsions, Intravenous; Heart Arrest; Humans; Rats; Resuscitation | 2006 |
Potential neurotoxicity of spinal anesthesia with lidocaine.
Topics: Adverse Drug Reaction Reporting Systems; Anesthesia, Spinal; Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Humans; Incidence; Lidocaine; Pain; Radiculopathy; Risk Factors; Spinal Nerves; Tetracaine | 2000 |
Cardiotoxicity with modern local anaesthetics: is there a safer choice?
Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Central Nervous System; Disease Models, Animal; Heart; Humans; Ropivacaine | 2001 |
107 other study(ies) available for bupivacaine and Disease Models, Animal
| Article | Year |
|---|---|
Apelin-13 Reverses Bupivacaine-Induced Cardiotoxicity via the Adenosine Monophosphate-Activated Protein Kinase Pathway.
Topics: AMP-Activated Protein Kinases; Animals; Bupivacaine; Cardiotoxicity; Cell Line; Disease Models, Animal; DNA Damage; Heart Diseases; Intercellular Signaling Peptides and Proteins; Male; Mitochondria, Heart; Myocytes, Cardiac; Oxidative Stress; Phosphatidylinositol 3-Kinase; Rats, Sprague-Dawley; Signal Transduction | 2021 |
Effects of intravenous lipid emulsions on the reversal of pacing-induced ventricular arrhythmias and electrophysiological alterations in an animal model of ropivacaine toxicity.
Topics: Anesthetics, Local; Animals; Arrhythmias, Cardiac; Bupivacaine; Disease Models, Animal; Fat Emulsions, Intravenous; Ropivacaine; Saline Solution; Swine | 2022 |
Intraoperative abobotulinumtoxinA alleviates pain after surgery and improves general wellness in a translational animal model.
Topics: Analgesics; Animals; Bupivacaine; Calcitonin Gene-Related Peptide; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Dorsal Horn; Swine | 2022 |
Novel charged sodium and calcium channel inhibitor active against neurogenic inflammation.
Topics: Animals; Bupivacaine; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Signaling; Disease Models, Animal; Ganglia, Spinal; Humans; Lidocaine; Mice; Neurogenic Inflammation; Nociceptors; Pain; Sodium Channel Blockers; Sodium Channels | 2019 |
Perineural dexamethasone attenuates liposomal bupivacaine-induced delayed neural inflammation in mice in vivo.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents; Bupivacaine; Dexamethasone; Disease Models, Animal; Drug Interactions; Inflammation; Male; Mice; Mice, Inbred C57BL; Time | 2020 |
Mechanistic study of mtROS-JNK-SOD2 signaling in bupivacaine-induced neuron oxidative stress.
Topics: Acetylcysteine; Animals; Anthracenes; Antioxidants; Bupivacaine; Cell Line, Tumor; Cyclic N-Oxides; Disease Models, Animal; Gene Knockdown Techniques; Humans; Injections, Spinal; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Mitochondria; Neurons; Neurotoxicity Syndromes; Oxidative Stress; Rats; Reactive Oxygen Species; RNA, Small Interfering; Superoxide Dismutase; Transcriptional Activation | 2020 |
Knockdown of lincRNA PADNA promotes bupivacaine-induced neurotoxicity by miR-194/FBXW7 axis.
Topics: 3' Untranslated Regions; Anesthetics, Local; Animals; Apoptosis; Bupivacaine; Cell Line; Cell Survival; Disease Models, Animal; Disease Susceptibility; F-Box-WD Repeat-Containing Protein 7; Ganglia, Spinal; Gene Expression Regulation; Gene Knockdown Techniques; Genetic Predisposition to Disease; Humans; Mice; MicroRNAs; Neurotoxicity Syndromes; RNA Interference; RNA, Long Noncoding | 2020 |
Bupivacaine-eluting soy protein structures for controlled release and localized pain relief: An in vitro and in vivo study.
Topics: Animals; Bupivacaine; Burns; Cell Death; Delayed-Action Preparations; Disease Models, Animal; Drug Liberation; Female; Fibroblasts; Humans; Male; Pain; Rats, Wistar; Soybean Proteins | 2021 |
Osmotically balanced, large unilamellar liposomes that enable sustained bupivacaine release for prolonged pain relief in in vivo rat models.
Topics: Animals; Bupivacaine; Disease Models, Animal; Male; Osmosis; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Unilamellar Liposomes | 2021 |
Acute Visceral Pain in Rats: Vagal Nerve Block Compared to Bupivacaine Administered Intramuscularly.
Topics: Acute Pain; Anesthetics, Local; Animals; Bupivacaine; Carrageenan; CD11b Antigen; Disease Models, Animal; Injections, Intramuscular; Male; Microglia; Pain Management; Peritonitis; Proto-Oncogene Proteins c-fos; Rats, Sprague-Dawley; Solitary Nucleus; Spinal Cord; Tumor Necrosis Factor-alpha; Vagotomy; Vagus Nerve; Visceral Pain | 2021 |
Effects of Remifentanil Pretreatment on Bupivacaine Cardiotoxicity in Rats.
Topics: Anesthetics, Local; Animals; Antidotes; Arrhythmias, Cardiac; Arterial Pressure; Bupivacaine; Cardiotoxicity; Disease Models, Animal; Drug Therapy, Combination; Fat Emulsions, Intravenous; Heart Arrest; Heart Conduction System; Heart Rate; Hypotension; Male; Rats, Wistar; Remifentanil | 2018 |
Levobuipivacaine-Induced Dissemination of A549 Lung Cancer Cells.
Topics: A549 Cells; Anesthetics, Local; Animals; Basic Helix-Loop-Helix Transcription Factors; Bupivacaine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Xenograft Model Antitumor Assays | 2017 |
Recovery From Ropivacaine-Induced or Levobupivacaine-Induced Cardiac Arrest in Rats: Comparison of Lipid Emulsion Effects.
Topics: Amides; Anesthetics, Local; Animals; Arterial Pressure; Biomarkers; Bupivacaine; Carbon Dioxide; Cardiopulmonary Resuscitation; Disease Models, Animal; Fat Emulsions, Intravenous; Female; Heart Arrest; Heart Rate; Hemodynamics; Hydrogen-Ion Concentration; Infusions, Intravenous; Levobupivacaine; Oxygen; Rats, Sprague-Dawley; Recovery of Function; Ropivacaine; Time Factors | 2017 |
MicroRNA-137 and its downstream target LSD1 inversely regulate anesthetics-induced neurotoxicity in dorsal root ganglion neurons.
Topics: Anesthetics; Animals; Bupivacaine; Disease Models, Animal; Down-Regulation; Ganglia, Spinal; Histone Demethylases; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Neurites; Neurons; Neuroprotection; Neurotoxicity Syndromes; Signal Transduction; Up-Regulation | 2017 |
Ropivacaine and Bupivacaine prevent increased pain sensitivity without altering neuroimmune activation following repeated social defeat stress.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Bupivacaine; Disease Models, Animal; Mice; Pain; Pain Measurement; Pain Threshold; Ropivacaine; Social Behavior; Stress, Psychological | 2018 |
Anti-nociceptive effects of bupivacaine-encapsulated PLGA nanoparticles applied to the compressed dorsal root ganglion in mice.
Topics: Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Nerve Compression Syndromes; Nociception; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2018 |
Myoprotective Potential of Creatine Is Greater than Whey Protein after Chemically-Induced Damage in Rat Skeletal Muscle.
Topics: Animals; Bupivacaine; Creatine; Cytoprotection; Dietary Supplements; Disease Models, Animal; Isometric Contraction; Male; Muscle Development; Muscle Proteins; Muscle, Skeletal; Muscular Diseases; Rats, Sprague-Dawley; Regeneration; Whey Proteins | 2018 |
Effect of four local anesthetics (tetracaine, proparacaine, lidocaine, and bupivacaine) on intraocular pressure in dogs.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Dogs; Female; Glaucoma; Intraocular Pressure; Lidocaine; Male; Propoxycaine; Tetracaine | 2019 |
Comparative Regimens of Lipid Rescue From Bupivacaine-Induced Asystole in a Rat Model.
Topics: Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Fat Emulsions, Intravenous; Heart Arrest; Infusions, Intravenous; Injections, Intravenous; Male; Random Allocation; Rats; Rats, Sprague-Dawley | 2019 |
Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication.
Topics: Anesthesia; Animals; Blood Pressure; Bupivacaine; Cardiotoxicity; Chloral Hydrate; Disease Models, Animal; Electrocardiography; Epinephrine; Heart Ventricles; Humans; Isoproterenol; Mice; Myocardial Contraction; Propanolamines; Rats; Reactive Oxygen Species | 2018 |
Effect of Artemisia Aucheri.L and Bupivacaine Encapsulated Nanoparticles on Nociceptive Pain.
Topics: Animals; Artemisia; Bupivacaine; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Synergism; Humans; Injections; Male; Metal Nanoparticles; Nanogels; Nociceptive Pain; Pain Measurement; Plant Extracts; Rats | 2019 |
Neurological and histological outcomes after subarachnoid injection of a liposomal bupivacaine suspension in pigs: a pilot study.
Topics: Anesthetics, Local; Animals; Bupivacaine; Delayed-Action Preparations; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Spinal; Neurotoxicity Syndromes; Pilot Projects; Subarachnoid Space; Swine | 2019 |
Reversing Effect of Insulin on Local Anesthetics-Induced Sciatic Nerve Block in Rats.
Topics: Anesthesia, Local; Animals; Bupivacaine; Disease Models, Animal; Drug Combinations; Humans; Insulin; Lidocaine; Nerve Block; Rats; Sciatic Nerve; Sciatic Neuropathy | 2019 |
Effects of Intradiscal Injection of Local Anesthetics on Intervertebral Disc Degeneration in Rabbit Degenerated Intervertebral Disc.
Topics: Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Intervertebral Disc; Intervertebral Disc Degeneration; Lidocaine; Nucleus Pulposus; Organ Culture Techniques; Rabbits | 2019 |
Comparative Effects of Sodium Bicarbonate and Intravenous Lipid Emulsions on Reversing Bupivacaine-Induced Electrophysiological Toxicity in a Porcine Experimental Model.
Topics: Action Potentials; Anesthetics, Local; Animals; Antidotes; Arrhythmias, Cardiac; Bupivacaine; Cardiotoxicity; Disease Models, Animal; Fat Emulsions, Intravenous; Heart Conduction System; Heart Rate; Recovery of Function; Sodium Bicarbonate; Sus scrofa; Time Factors | 2019 |
Insulin/glucose infusion successfully resuscitates bupivacaine-induced sudden-onset circulatory collapse in dogs.
Topics: Anesthetics, Local; Animals; Arterial Pressure; Bupivacaine; Cardiac Output; Disease Models, Animal; Dogs; Electrocardiography; Glucose; Injections, Intravenous; Insulin; Male; Random Allocation; Resuscitation; Shock; Time Factors; Treatment Outcome | 2013 |
Diphenhydramine produces local cutaneous analgesia in response to dorsal skin noxious stimuli in the rat.
Topics: Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Delayed-Action Preparations; Diphenhydramine; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Pain; Rats; Rats, Sprague-Dawley; Skin; Time Factors | 2014 |
Extended release local anesthetic agents in a postoperative arthritic pain model.
Topics: Anesthetics; Anesthetics, Local; Animals; Bupivacaine; Castor Oil; Chemistry, Pharmaceutical; Delayed-Action Preparations; Disease Models, Animal; Knee Joint; Lactic Acid; Male; Pain Measurement; Pain, Postoperative; Polyesters; Polymers; Rats; Rats, Sprague-Dawley | 2014 |
Effect of long-chain triglyceride lipid emulsion on bupivacaine-induced changes in electrophysiological parameters of rabbit Purkinje cells.
Topics: Action Potentials; Anesthetics, Local; Animals; Bupivacaine; Cardiotoxicity; Disease Models, Animal; Emulsions; Male; Purkinje Cells; Rabbits; Random Allocation; Triglycerides | 2014 |
Influence of the peritoneal lavage with bupivacaine on the survival and resistance of colonic anastomoses performed under fecal peritonitis in rats.
Topics: Anastomosis, Surgical; Anesthetics, Local; Animals; Bupivacaine; Colon; Disease Models, Animal; Feces; Male; Peritoneal Lavage; Peritonitis; Postoperative Period; Random Allocation; Rats; Rats, Wistar; Reproducibility of Results; Survival Rate; Time Factors; Treatment Outcome | 2013 |
Resuscitation with lipid emulsion: dose-dependent recovery from cardiac pharmacotoxicity requires a cardiotonic effect.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Fat Emulsions, Intravenous; Heart; Heart Arrest; Heart Rate; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Resuscitation; Sodium Chloride; Time Factors; Treatment Outcome | 2014 |
Extended duration local anesthetic agent in a rat paw model.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Bupivacaine; Castor Oil; Chemistry, Pharmaceutical; Delayed-Action Preparations; Disease Models, Animal; Male; Motor Activity; Pain Threshold; Pain, Postoperative; Polyesters; Rats, Sprague-Dawley; Sciatic Nerve; Solubility; Technology, Pharmaceutical | 2014 |
Selective activation of α7 nicotinic acetylcholine receptor (nAChRα7) inhibits muscular degeneration in mdx dystrophic mice.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Bupivacaine; Cell Death; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Male; Mice, Inbred C57BL; Mice, Inbred mdx; Mice, Knockout; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Necrosis; Nicotinic Agonists; Nicotinic Antagonists; Regeneration | 2014 |
Effects of analgesic use on inflammation and hematology in a murine model of venous thrombosis.
Topics: Analgesics; Anesthetics, Local; Animals; Bupivacaine; Buprenorphine; Carbazoles; Disease Models, Animal; Inflammation; Ligation; Male; Mice; Mice, Inbred C57BL; Random Allocation; Tramadol; Vena Cava, Inferior; Venous Thrombosis | 2014 |
Efficacy of resuscitation with Intralipid in a levobupivacaine-induced cardiac arrest model.
Topics: Anesthetics, Local; Animals; Bupivacaine; Coronary Circulation; Disease Models, Animal; Drug Therapy, Combination; Emulsions; Epinephrine; Fat Emulsions, Intravenous; Heart Arrest; Levobupivacaine; Phospholipids; Rabbits; Random Allocation; Resuscitation; Soybean Oil; Vasoconstrictor Agents | 2014 |
Dexamethasone as adjuvant to bupivacaine prolongs the duration of thermal antinociception and prevents bupivacaine-induced rebound hyperalgesia via regional mechanism in a mouse sciatic nerve block model.
Topics: Anesthetics, Local; Animals; Axons; Bupivacaine; Chemotherapy, Adjuvant; Dexamethasone; Disease Models, Animal; Humans; Hyperalgesia; Male; Mice; Nerve Block; Nerve Degeneration; Pain Measurement; Peripheral Nerves; Sciatic Nerve | 2015 |
Heat-Stress effects on the myosin heavy chain phenotype of rat soleus fibers during the early stages of regeneration.
Topics: Anesthetics, Local; Animals; Body Weight; Bupivacaine; Cell Count; Disease Models, Animal; Heat Stress Disorders; HSP72 Heat-Shock Proteins; Male; Muscle Fibers, Skeletal; Muscle, Skeletal; MyoD Protein; Myosin Heavy Chains; Oncogene Proteins; Organ Size; Paired Box Transcription Factors; Phenotype; Protein Isoforms; Rats; Rats, Wistar; Regeneration; Satellite Cells, Skeletal Muscle; Time Factors | 2015 |
Involvement of Opioid Receptors in the Lipid Rescue of Bupivacaine-Induced Cardiotoxicity.
Topics: Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Dose-Response Relationship, Drug; Fat Emulsions, Intravenous; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart Arrest; Heart Rate; Male; Myocardium; Narcotic Antagonists; Phosphorylation; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Signal Transduction; Stroke Volume; Time Factors | 2015 |
The Local and Systemic Actions of Duloxetine in Allodynia and Hyperalgesia Using a Rat Skin Incision Pain Model.
Topics: Administration, Cutaneous; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Cells, Cultured; Dermatologic Surgical Procedures; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hyperalgesia; Injections, Intraperitoneal; Male; Pain Measurement; Pain, Postoperative; Pituitary Gland; Rats, Sprague-Dawley; Sciatic Nerve; Sodium Channel Blockers; Sodium Channels; Thiophenes; Time Factors | 2015 |
Electrophysiological, haemodynamic, and mitochondrial alterations induced by levobupivacaine during myocardial ischemia in a pig model: protection by lipid emulsions?
Topics: Action Potentials; Anesthetics, Local; Animals; Arterial Pressure; Bradycardia; Bupivacaine; Calcium; Cytoprotection; Disease Models, Animal; Emulsions; Heart Conduction System; Heart Rate; Hemodynamics; Injections, Intravenous; Levobupivacaine; Lipid Peroxidation; Mitochondria, Heart; Myocardial Ischemia; Myocytes, Cardiac; Oxidative Phosphorylation; Oxidative Stress; Oxygen Consumption; Phospholipids; Soybean Oil; Sus scrofa; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left | 2015 |
Conditioned place preference and spontaneous dorsal horn neuron activity in chronic constriction injury model in rats.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Bupivacaine; Conditioning, Psychological; Disease Models, Animal; Foot Injuries; Hyperalgesia; Ligation; Male; Nerve Block; Neuralgia; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2015 |
Insulin Signaling in Bupivacaine-induced Cardiac Toxicity: Sensitization during Recovery and Potentiation by Lipid Emulsion.
Topics: AMP-Activated Protein Kinases; Anesthesia Recovery Period; Anesthetics, Local; Animals; Blotting, Western; Bupivacaine; Cardiotoxicity; Disease Models, Animal; Drug Synergism; Fat Emulsions, Intravenous; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart; In Vitro Techniques; Insulin; Myocardium; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2016 |
Analgesic Effect of Intra-Articular Injection of Temperature-Responsive Hydrogel Containing Bupivacaine on Osteoarthritic Pain in Rats.
Topics: Analgesics; Anesthetics, Local; Animals; Arthralgia; Behavior, Animal; Bupivacaine; Chronic Pain; Disease Models, Animal; Hydrogel, Polyethylene Glycol Dimethacrylate; Injections, Intra-Articular; Male; Osteoarthritis; Rats; Rats, Sprague-Dawley | 2015 |
Comparison of histopathological effects of perineural administration of bupivacaine and bupivacaine-dexmedetomidine in rat sciatic nerve.
Topics: Anesthetics, Local; Animals; Bupivacaine; Dexmedetomidine; Disease Models, Animal; Microscopy, Electron, Transmission; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2016 |
Electroacupuncture pretreatment induces rapid tolerance to bupivacaine cardiotoxicity in rats.
Topics: Anesthetics, Local; Animals; Arrhythmias, Cardiac; Arterial Pressure; Blood Pressure; Bupivacaine; Cardiotoxicity; Disease Models, Animal; Drug Tolerance; Electroacupuncture; Heart Arrest; Heart Rate; Male; Pre-Exposure Prophylaxis; Rats; Rats, Sprague-Dawley; Time Factors; Treatment Outcome | 2016 |
Bupivacaine increases the rate of motoneuron death following peripheral nerve injury.
Topics: Animals; Axotomy; Bupivacaine; Cell Death; Disease Models, Animal; Lidocaine; Male; Mice; Mice, Inbred C57BL; Motor Neurons; Peripheral Nerve Injuries | 2017 |
Nociceptive inhibition prevents inflammatory pain induced changes in the blood-brain barrier.
Topics: Anesthetics, Local; Animals; Blood-Brain Barrier; Brain Edema; Bupivacaine; Carrageenan; Claudin-5; Disease Models, Animal; Hyperalgesia; Inflammation; Membrane Proteins; Nerve Block; Nociceptors; Occludin; Pain; Phosphoproteins; Rats; Sensory Receptor Cells; Signal Transduction; Sucrose; Tight Junctions; Zonula Occludens-1 Protein | 2008 |
Lipid emulsion is superior to vasopressin in a rodent model of resuscitation from toxin-induced cardiac arrest.
Topics: Animals; Bupivacaine; Disease Models, Animal; Epinephrine; Fat Emulsions, Intravenous; Heart Arrest; Male; Rats; Rats, Sprague-Dawley; Resuscitation; Vasoconstrictor Agents; Vasopressins | 2009 |
Early blockade of injured primary sensory afferents reduces glial cell activation in two rat neuropathic pain models.
Topics: Animals; Biomarkers; Bupivacaine; CD11b Antigen; Disease Models, Animal; Ganglia, Spinal; Glial Fibrillary Acidic Protein; Gliosis; Ligation; Male; Microglia; Nerve Growth Factor; Neuralgia; Peripheral Nerve Injuries; Peripheral Nerves; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Satellite Cells, Perineuronal; Sensory Receptor Cells; Sodium Channel Blockers; Tetrodotoxin; Time Factors | 2009 |
Inhibition of prostaglandin D synthase suppresses muscular necrosis.
Topics: Anesthetics, Local; Animals; Blotting, Western; Bupivacaine; Cytokines; Disease Models, Animal; Humans; Intramolecular Oxidoreductases; Lipocalins; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Mice, Knockout; Mice, Transgenic; Muscle, Skeletal; Muscular Dystrophy, Animal; Necrosis; Piperidines; Prostaglandin D2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2009 |
The effect of epidural anaesthesia on the reverse-flow fasciocutaneous flap: an experimental study in rabbits.
Topics: Anesthesia, Epidural; Anesthetics, Local; Animals; Blood Pressure; Bupivacaine; Disease Models, Animal; Laser-Doppler Flowmetry; Microcirculation; Rabbits; Skin; Skin Transplantation; Surgical Flaps | 2010 |
Lipid emulsion combined with epinephrine and vasopressin does not improve survival in a swine model of bupivacaine-induced cardiac arrest.
Topics: Animals; Bupivacaine; Disease Models, Animal; Drug Therapy, Combination; Epinephrine; Fat Emulsions, Intravenous; Female; Heart Arrest; Male; Survival Rate; Swine; Vasopressins | 2009 |
Comparison of skin incision vs. skin plus deep tissue incision on ongoing pain and spontaneous activity in dorsal horn neurons.
Topics: Action Potentials; Anesthetics, Local; Animals; Behavior, Animal; Bupivacaine; Dermatologic Surgical Procedures; Disease Models, Animal; Hot Temperature; Hyperalgesia; Male; Nociceptors; Pain Measurement; Pain Threshold; Pain, Postoperative; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Skin; Spinothalamic Tracts; Subcutaneous Fat; Synaptic Transmission; Treatment Outcome | 2009 |
Evaluation of the Association of Anaesthetists of Great Britain and Ireland lipid infusion protocol in bupivacaine induced cardiac arrest in rabbits.
Topics: Anesthetics, Local; Animals; Bupivacaine; Clinical Protocols; Disease Models, Animal; Electrocardiography; Fat Emulsions, Intravenous; Female; Heart Arrest; Hemodynamics; Male; Rabbits | 2009 |
Oxidative stress of intracameral lidocaine and levobupivacaine on ocular tissues.
Topics: Anesthetics, Local; Animals; Anterior Chamber; Bupivacaine; Cornea; Corneal Opacity; Disease Models, Animal; Lens, Crystalline; Levobupivacaine; Lidocaine; Malondialdehyde; Oxidative Stress; Rabbits; Sulfhydryl Compounds | 2010 |
Electrocardiographic alterations during intravascular application of three different test doses of bupivacaine and epinephrine: experimental study in neonatal pigs.
Topics: Anesthetics, Local; Animals; Animals, Newborn; Bupivacaine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Electrocardiography; Epinephrine; Female; Heart Rate; Male; Stimulation, Chemical; Sus scrofa | 2010 |
Sphingosine 1-phosphate signaling is involved in skeletal muscle regeneration.
Topics: Animals; Bupivacaine; Cell Membrane; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Injections, Intramuscular; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Muscle Development; Muscle, Skeletal; Muscular Diseases; Rats; Rats, Wistar; Receptors, Lysosphingolipid; Regeneration; Satellite Cells, Skeletal Muscle; Signal Transduction; Sphingosine; Time Factors | 2010 |
Anesthetic effects and lipid resuscitation protocols.
Topics: Anesthetics; Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Dogs; Epinephrine; Fat Emulsions, Intravenous; Heart Arrest; Hypnotics and Sedatives; Rats; Resuscitation; Species Specificity; Swine; Vasoconstrictor Agents; Vasopressins | 2010 |
Effects of a bupivacaine nerve block on the axonal transport of Tumor Necrosis Factor-alpha (TNF-alpha) in a rat model of carrageenan-induced inflammation.
Topics: Anesthetics, Local; Animals; Axonal Transport; Bupivacaine; Carrageenan; Disease Models, Animal; Edema; Femoral Nerve; Fluorescence; Foot; Ganglia, Spinal; Injections, Subcutaneous; Male; Nerve Block; Neurogenic Inflammation; Polymerase Chain Reaction; Polysaccharides; Rats; Rats, Sprague-Dawley; Receptors, Tumor Necrosis Factor, Type I; Tetrodotoxin; Tumor Necrosis Factor-alpha | 2010 |
Clinically relevant doses of lidocaine and bupivacaine do not impair cutaneous wound healing in mice.
Topics: Aging; Anesthetics, Local; Animals; Bupivacaine; Collagen; Dermatologic Surgical Procedures; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Lidocaine; Mice; Mice, Inbred C57BL; Postmenopause; Skin; Wound Healing | 2010 |
Anti-inflammatory efficiency of levobupivacaine in an experimental colitis model.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents; Budesonide; Bupivacaine; Colitis; Disease Models, Animal; Levobupivacaine; Male; Rats; Rats, Sprague-Dawley | 2010 |
Effect of hypertonic saline on electrocardiography QRS duration in rabbit model of bupivacaine toxicity resuscitated by intravenous lipid.
Topics: Anesthetics, Local; Animals; Blood Pressure; Bupivacaine; Coronary Circulation; Disease Models, Animal; Electrocardiography; Fat Emulsions, Intravenous; Female; Heart Arrest; Heart Rate; Male; Rabbits; Saline Solution, Hypertonic | 2010 |
Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Dinoprostone; Disease Models, Animal; Edema; Hyperalgesia; Inflammation; Inflammation Mediators; Injections, Subcutaneous; Interleukin-1beta; Ketoprofen; Male; Nerve Block; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Sciatic Nerve; Tumor Necrosis Factor-alpha | 2010 |
Do local anesthetics have antibacterial effect on Staphylococcus aureus under in vivo conditions? An experimental study.
Topics: Anesthetics, Local; Animals; Bupivacaine; Carticaine; Disease Models, Animal; Lidocaine; Male; Prilocaine; Rats; Rats, Sprague-Dawley; Staphylococcal Infections; Staphylococcus aureus; Surgical Wound Infection | 2010 |
Concentration-dependent bupivacaine myotoxicity in rabbit extraocular muscle.
Topics: Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Dose-Response Relationship, Drug; Follow-Up Studies; Injections, Intramuscular; Necrosis; Oculomotor Muscles; Rabbits | 2010 |
Analgesic and antiallodynic effects of antidepressants after infiltration into the rat.
Topics: Adrenergic Uptake Inhibitors; Analgesics; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Bupivacaine; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Male; Pain; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Selective Serotonin Reuptake Inhibitors; Time Factors | 2010 |
Spinal anesthesia in infant rats: development of a model and assessment of neurologic outcomes.
Topics: Anesthesia, Spinal; Animals; Animals, Newborn; Blood Gas Analysis; Bupivacaine; Disease Models, Animal; Female; Isoflurane; Male; Nervous System Diseases; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2011 |
The safety and tolerability evaluation of DepoFoam bupivacaine (bupivacaine extended-release liposome injection) administered by incision wound infiltration in rabbits and dogs.
Topics: Anesthetics, Local; Animals; Bupivacaine; Delayed-Action Preparations; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Female; Hernia, Inguinal; Injections; Liposomes; Male; Pain, Postoperative; Rabbits; Random Allocation; Wound Healing | 2011 |
Bupivacaine injection leads to muscle force reduction and histologic changes in a murine model.
Topics: Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Isometric Contraction; Male; Muscle, Skeletal; Rats | 2011 |
Comparison of actions of systemically and locally administrated local anaesthetics in diabetic rats with painful neuropathy.
Topics: Anesthetics, Local; Animals; Bupivacaine; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Hyperalgesia; Hyperglycemia; Injections, Intraperitoneal; Levobupivacaine; Lidocaine; Neuralgia; Rats; Rats, Wistar | 2013 |
Lipid resuscitation of bupivacaine toxicity: long-chain triglyceride emulsion provides benefits over long- and medium-chain triglyceride emulsion.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Bronchodilator Agents; Bupivacaine; Disease Models, Animal; Emulsions; Epinephrine; Fat Emulsions, Intravenous; Heart Arrest; Lipids; Male; Phospholipids; Rats; Rats, Sprague-Dawley; Resuscitation; Soybean Oil; Triglycerides | 2011 |
Repeated microinjections into the medial prefrontal cortex (mPFC) impair extinction of conditioned place preference in mice.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Central Nervous System Depressants; Conditioning, Operant; Disease Models, Animal; Ethanol; Extinction, Psychological; Learning Disabilities; Male; Meloxicam; Mice; Mice, Inbred DBA; Microinjections; Prefrontal Cortex; Thiazines; Thiazoles; Time Factors | 2012 |
Association of sustained cardiovascular recovery with epinephrine in the delayed lipid-based resuscitation from cardiac arrest induced by bupivacaine overdose in rats.
Topics: Anesthetics, Local; Animals; Bupivacaine; Combined Modality Therapy; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Overdose; Epinephrine; Fat Emulsions, Intravenous; Heart Arrest; Hemodynamics; Lung; Male; Myocardium; Organ Size; Rats; Rats, Sprague-Dawley; Treatment Outcome; Vasoconstrictor Agents | 2012 |
Assessment of ventricular electrophysiological characteristics at periinfarct zone of postmyocardial infarction in rabbits following stellate ganglion block.
Topics: Action Potentials; Anesthetics, Local; Animals; Arrhythmias, Cardiac; Autonomic Nerve Block; Bupivacaine; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Endocardium; Female; Heart Ventricles; Male; Myocardial Infarction; Myocardium; Pericardium; Rabbits; Refractory Period, Electrophysiological; Stellate Ganglion; Time Factors; Ventricular Function | 2012 |
Effect of local anaesthetic infiltration with bupivacaine and ropivacaine on wound healing: a placebo-controlled study.
Topics: Amides; Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Male; Pain Measurement; Pain, Postoperative; Rats; Rats, Wistar; Ropivacaine; Treatment Outcome; Wound Healing; Wounds and Injuries | 2014 |
Effect of cervical sympathetic block on cerebral vasospasm after subarachnoid hemorrhage in rabbits.
Topics: Anesthetics, Local; Animals; Autonomic Nerve Block; Basilar Artery; Bupivacaine; Disease Models, Animal; Male; Neurologic Examination; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Radiography; Random Allocation; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2013 |
The effect of local hematoma blocks on early fracture healing.
Topics: Analysis of Variance; Animals; Bupivacaine; Disease Models, Animal; Femoral Fractures; Fracture Fixation; Fracture Healing; Hematoma; Injections, Intralesional; Lidocaine; Male; Probability; Random Allocation; Rats; Rats, Long-Evans; Reference Values; Sensitivity and Specificity; Tensile Strength; Weight-Bearing | 2002 |
Skeletal muscle regeneration associated with the stroma reaction during tumor invasion in the rat tongue.
Topics: 4-Nitroquinoline-1-oxide; Acetylcholinesterase; Animals; Biomarkers, Tumor; Bupivacaine; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; Female; Immunoenzyme Techniques; Microscopy, Electron; Muscle, Skeletal; Myofibrils; Neoplasm Invasiveness; Rats; Rats, Wistar; Regeneration; Specific Pathogen-Free Organisms; Stromal Cells; Succinate Dehydrogenase; Tongue Neoplasms | 2002 |
Sympathetic blockade in a canine model of gram-negative bacterial peritonitis.
Topics: Animals; Blood Pressure; Bupivacaine; Cardiac Output; Disease Models, Animal; Dogs; Escherichia coli; Escherichia coli Infections; Gram-Negative Bacterial Infections; Hemodynamics; Morphine; Pain; Pain Measurement; Peritonitis; Pulmonary Artery; Reference Values; Sympathetic Nervous System | 2003 |
Involvement of the anterior pretectal nucleus in the control of persistent pain: a behavioral and c-Fos expression study in the rat.
Topics: Anesthetics, Local; Animals; Bupivacaine; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Functional Laterality; Hyperalgesia; Immunohistochemistry; Lidocaine; Male; Mesencephalon; Microinjections; Pain; Pain Measurement; Pain Threshold; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Skin; Spinal Cord | 2003 |
Antihyperalgesic effect of simultaneously released hydromorphone and bupivacaine from polymer fibers in the rat chronic constriction injury model.
Topics: Analgesics, Opioid; Animals; Bupivacaine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Implants; Drug Therapy, Combination; Hindlimb; Hot Temperature; Hydromorphone; Hyperalgesia; Lactic Acid; Ligation; Male; Pain; Pain Measurement; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2003 |
Intrathecal bupivacaine protects against extension of lesions in an acute photochemical spinal cord injury model.
Topics: Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Disease Progression; Evoked Potentials, Somatosensory; Injections, Spinal; Male; Motor Activity; Neuroprotective Agents; Photochemistry; Prospective Studies; Random Allocation; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Statistics, Nonparametric; Time Factors; Treatment Outcome | 2004 |
Contralateral effect of amitriptyline and bupivacaine for sciatic nerve block in an animal model of inflammation.
Topics: Amitriptyline; Anesthetics, Local; Animals; Bupivacaine; Carrageenan; Disease Models, Animal; Hyperalgesia; Male; Microspheres; Nerve Block; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2004 |
Beneficial effect of trimebutine and N-monodesmethyl trimebutine on trinitrobenzene sulfonic acid-induced colitis in rats.
Topics: Administration, Rectal; Anesthetics, Local; Animals; Bupivacaine; Colitis; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Agents; Injections, Subcutaneous; Lidocaine; Male; Organ Size; Rats; Rats, Sprague-Dawley; Trimebutine; Trinitrobenzenesulfonic Acid | 2004 |
Neuropathic pain: early spontaneous afferent activity is the trigger.
Topics: Action Potentials; Analysis of Variance; Anesthetics, Local; Animals; Axotomy; Behavior, Animal; Bupivacaine; Disease Models, Animal; Dose-Response Relationship, Drug; Functional Laterality; Hot Temperature; Hyperalgesia; Ligation; Male; Nerve Block; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Reaction Time; Sciatic Neuropathy; Tetrodotoxin; Time Factors; Touch | 2005 |
Local anaesthetics attenuates spinal nociception and HPA-axis activation during experimental laparotomy in pigs.
Topics: Adrenocorticotropic Hormone; Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; C-Reactive Protein; Disease Models, Animal; Female; Hydrocortisone; Hypothalamo-Hypophyseal System; Interleukin-6; Laparotomy; Lidocaine; Male; Pain; Pituitary-Adrenal System; Swine; Swine Diseases | 2005 |
Notexin causes greater myotoxic damage and slower functional repair in mouse skeletal muscles than bupivacaine.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cell Death; Cytotoxins; Disease Models, Animal; Elapid Venoms; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Diseases; Neurotoxins; Recovery of Function; Regeneration; Time Factors | 2006 |
Chondrolysis after continuous intra-articular bupivacaine infusion: an experimental model investigating chondrotoxicity in the rabbit shoulder.
Topics: Analgesia, Patient-Controlled; Anesthetics, Local; Animals; Bupivacaine; Cartilage Diseases; Cartilage, Articular; Disease Models, Animal; Drug Combinations; Epinephrine; Injections, Intra-Articular; Pain, Postoperative; Rabbits; Shoulder Joint; Synovial Membrane | 2006 |
Ropivacaine may have advantages compared to bupivacaine in porcine endotoxemic shock.
Topics: Amides; Anesthetics, Local; Animals; Blood Platelets; Blood Pressure; Bupivacaine; Disease Models, Animal; Endotoxemia; Lipid Peroxidation; Platelet Count; Protective Agents; Ropivacaine; Shock, Septic; Stroke Volume; Sus scrofa; Ventricular Function, Left | 2006 |
Rat pain-related responses induced by experimental scorpion BmK sting.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Hyperalgesia; Indomethacin; Morphine; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Scorpions; Skin; Time Factors | 2006 |
Nerve conduction blockade in the sciatic nerve prevents but does not reverse the activation of p38 mitogen-activated protein kinase in spinal microglia in the rat spared nerve injury model.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Blotting, Western; Bupivacaine; Disease Models, Animal; Enzyme Activation; Injections, Spinal; Male; Microglia; Microspheres; Nerve Block; Neural Conduction; Neuralgia; p38 Mitogen-Activated Protein Kinases; Pain Measurement; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Nerves; Time Factors | 2007 |
Caveat injector.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cartilage, Articular; Cell Death; Chondrocytes; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Injections, Intra-Articular; Joint Diseases; Rabbits | 2007 |
Cognitive impairment due to surgery or postoperative complications?
Topics: Anesthetics, Local; Animals; Bupivacaine; Cognition Disorders; Disease Models, Animal; Male; Maze Learning; Mobility Limitation; Postoperative Complications; Rats; Rats, Sprague-Dawley; Research Design; Splenectomy; Surgical Procedures, Operative; Surgical Wound Infection | 2007 |
A comparison of the combination of epinephrine and vasopressin with lipid emulsion in a porcine model of asphyxial cardiac arrest after intravenous injection of bupivacaine.
Topics: Anesthetics, Local; Animals; Asphyxia; Bupivacaine; Cardiopulmonary Resuscitation; Coronary Circulation; Disease Models, Animal; Electric Countershock; Epinephrine; Fat Emulsions, Intravenous; Female; Heart Arrest; Hemodynamics; Injections, Intravenous; Male; Swine; Time Factors; Vasoconstrictor Agents; Vasopressins | 2008 |
Resuscitation with lipid versus epinephrine in a rat model of bupivacaine overdose.
Topics: Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Drug Overdose; Epinephrine; Heart; Infusions, Intravenous; Lipids; Male; Rats; Rats, Sprague-Dawley; Resuscitation | 2008 |
[Role of nitric oxide in the nociceptive information transmission in the spinal cord].
Topics: Animals; Bupivacaine; Disease Models, Animal; Dizocilpine Maleate; Humans; Neuronal Plasticity; Nitric Oxide; Nociceptors; Pain; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1994 |
A rat model for investigation of spinal mechanisms in detrusor instability associated with infravesical outflow obstruction.
Topics: Animals; Bupivacaine; Disease Models, Animal; Female; Hypertrophy; Injections, Spinal; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Rats; Rats, Sprague-Dawley; Spinal Cord; Urinary Bladder; Urinary Bladder Neck Obstruction | 1993 |
Combined epidural analgesia and general anesthesia induce ischemia distal to a severe coronary artery stenosis in swine.
Topics: Anesthesia, Epidural; Anesthesia, General; Animals; Blood Pressure; Bupivacaine; Coronary Circulation; Coronary Disease; Depression, Chemical; Disease Models, Animal; Heart; Heart Rate; Injections, Epidural; Male; Myocardial Ischemia; Swine | 1994 |
Effects of high thoracic epidural anaesthesia on the peripheral airway reactivity in dogs.
Topics: Acetylcholine; Airway Resistance; Analysis of Variance; Anesthesia, Epidural; Anesthetics, Local; Animals; Blood Pressure; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Bupivacaine; Carbon Dioxide; Cardiac Output; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Histamine; Male; Pressure; Pulmonary Wedge Pressure; Sympathectomy; Sympathetic Nervous System; Sympatholytics; Thoracic Vertebrae; Time Factors | 1998 |
The effects of verapamil and nimodipine on bupivacaine-induced cardiotoxicity in rats: an in vivo and in vitro study.
Topics: Anesthetics, Local; Animals; Arrhythmias, Cardiac; Blood Pressure; Bupivacaine; Calcium Channel Blockers; Confidence Intervals; Coronary Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Heart; Heart Rate; Incidence; Injections, Intravenous; Lethal Dose 50; Male; Myocardial Contraction; Nimodipine; Premedication; Rats; Rats, Sprague-Dawley; Survival Rate; Verapamil | 1998 |
The effect of epidural injection of betamethasone or bupivacaine in a rat model of lumbar radiculopathy.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Betamethasone; Bupivacaine; Calcitonin Gene-Related Peptide; Cell Count; Disease Models, Animal; Glucocorticoids; Immunohistochemistry; Injections, Epidural; Lumbar Vertebrae; Male; Motor Activity; Polyradiculopathy; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Substance P | 1998 |
[Moderating action of celiac block in experimental pancreatitis in the dog].
Topics: Acute Disease; Anesthetics, Local; Animals; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Disease Models, Animal; Dogs; Female; Male; Pancreatitis | 1999 |
Lack of pre-emptive analgesic effects of local anaesthetics on neuropathic pain.
Topics: Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Lidocaine; Male; Pain Threshold; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Spinal Nerves | 2000 |
Intramyocardial transplantation of autologous myoblasts: can tissue processing be optimized?
Topics: Animals; Bupivacaine; Cell Count; Cell Survival; Cells, Cultured; Disease Models, Animal; Echocardiography; Graft Survival; Immunohistochemistry; Ischemic Preconditioning, Myocardial; Male; Muscle, Skeletal; Myocardial Infarction; Myocardium; Myosin Heavy Chains; Rats; Rats, Wistar; Transplantation, Autologous; Ventricular Function, Left | 2000 |
Influence of postoperative epidural analgesia with bupivacaine on intestinal motility, transit time, and anastomotic healing.
Topics: Analgesia, Epidural; Anastomosis, Surgical; Anesthetics, Local; Animals; Bupivacaine; Colectomy; Disease Models, Animal; Dogs; Female; Gastrointestinal Motility; Gastrointestinal Transit; Myoelectric Complex, Migrating; Postoperative Care; Time Factors; Wound Healing | 2002 |
Impaired regeneration of dystrophin-deficient muscle fibers is caused by exhaustion of myogenic cells.
Topics: Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Male; Mice; Mice, Inbred mdx; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Regeneration | 2002 |
Intrathecal MK-801 and local nerve anesthesia synergistically reduce nociceptive behaviors in rats with experimental peripheral mononeuropathy.
Topics: Anesthesia, Local; Animals; Bupivacaine; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Nociceptors; Pain; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains; Sciatic Nerve; Spinal Cord; Time Factors | 1992 |