bupivacaine has been researched along with Degenerative Disc Disease in 16 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "From 52 patients with low back pain, we selected 42 who showed disc degeneration at only one level (L4-L5 or L5-S1) on magnetic resonance imaging and were diagnosed by pain provocation on discography and pain relief by discoblock (the injection of bupivacaine)." | 9.19 | Injection of bupivacaine into disc space to detect painful nonunion after anterior lumbar interbody fusion (ALIF) surgery in patients with discogenic low back pain. ( Aoki, Y; Eguchi, Y; Inage, K; Inoue, G; Ishikawa, T; Kamoda, H; Kimura, S; Kishida, S; Kubota, G; Kuniyoshi, K; Miyagi, M; Nakamura, J; Ochiai, N; Ohtori, S; Oikawa, Y; Orita, S; Sainoh, T; Sakuma, Y; Sato, J; Suzuki, M; Takahashi, K; Takaso, M; Toyone, T; Yamauchi, K, 2014) |
| "From 52 patients with low back pain, we selected 42 who showed disc degeneration at only one level (L4-L5 or L5-S1) on magnetic resonance imaging and were diagnosed by pain provocation on discography and pain relief by discoblock (the injection of bupivacaine)." | 5.19 | Injection of bupivacaine into disc space to detect painful nonunion after anterior lumbar interbody fusion (ALIF) surgery in patients with discogenic low back pain. ( Aoki, Y; Eguchi, Y; Inage, K; Inoue, G; Ishikawa, T; Kamoda, H; Kimura, S; Kishida, S; Kubota, G; Kuniyoshi, K; Miyagi, M; Nakamura, J; Ochiai, N; Ohtori, S; Oikawa, Y; Orita, S; Sainoh, T; Sakuma, Y; Sato, J; Suzuki, M; Takahashi, K; Takaso, M; Toyone, T; Yamauchi, K, 2014) |
| "Infiltration procedures are a common treatment of lumbar radiculopathy." | 1.42 | CT-guided infiltration saves surgical intervention and fastens return to work compared to anatomical landmark-guided infiltration in patients with lumbosciatica. ( Buhr, M; Deml, MC; Kabir, K; Pflugmacher, R; Riedel, R; Rommelspacher, Y; Wimmer, MD, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (75.00) | 24.3611 |
| 2020's | 4 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roh, MS | 1 |
| Kucher, OA | 1 |
| Shick, KM | 1 |
| Knolhoff, DR | 1 |
| McGarvey, JS | 1 |
| Peterson, SC | 1 |
| Shamov, T | 1 |
| Al-Hashel, JY | 1 |
| Rоusseff, RT | 1 |
| Villavicencio, AT | 1 |
| Rajpal, S | 1 |
| Nelson, EL | 1 |
| Beasley, K | 1 |
| Kantha, V | 1 |
| Burneikiene, S | 1 |
| Bicak, M | 1 |
| Aktas, U | 1 |
| Salik, F | 1 |
| Akelma, H | 1 |
| Bicak, EA | 1 |
| Kaya, S | 1 |
| Kolcun, JPG | 1 |
| Brusko, GD | 1 |
| Basil, GW | 1 |
| Epstein, R | 1 |
| Wang, MY | 1 |
| Ura, K | 1 |
| Sudo, H | 2 |
| Iwasaki, K | 2 |
| Tsujimoto, T | 2 |
| Ukeba, D | 1 |
| Iwasaki, N | 2 |
| Kimura, S | 1 |
| Ohtori, S | 2 |
| Orita, S | 2 |
| Inoue, G | 2 |
| Eguchi, Y | 2 |
| Takaso, M | 2 |
| Ochiai, N | 2 |
| Kuniyoshi, K | 2 |
| Aoki, Y | 2 |
| Ishikawa, T | 2 |
| Miyagi, M | 2 |
| Kamoda, H | 2 |
| Suzuki, M | 3 |
| Sakuma, Y | 1 |
| Kubota, G | 1 |
| Oikawa, Y | 1 |
| Inage, K | 1 |
| Sainoh, T | 1 |
| Yamauchi, K | 2 |
| Toyone, T | 2 |
| Nakamura, J | 2 |
| Kishida, S | 2 |
| Sato, J | 1 |
| Takahashi, K | 2 |
| Proietti, L | 1 |
| Schirò, GR | 1 |
| Sessa, S | 1 |
| Scaramuzzo, L | 1 |
| Yamada, K | 1 |
| Higashi, H | 1 |
| Ohnishi, T | 1 |
| Deml, MC | 1 |
| Buhr, M | 1 |
| Wimmer, MD | 1 |
| Pflugmacher, R | 1 |
| Riedel, R | 1 |
| Rommelspacher, Y | 1 |
| Kabir, K | 1 |
| Strube, P | 1 |
| Pfitzner, BM | 1 |
| Streitparth, F | 1 |
| Hartwig, T | 1 |
| Putzier, M | 1 |
| Yilmaz, C | 1 |
| Buyrukcu, SO | 1 |
| Cansever, T | 1 |
| Gulsen, S | 1 |
| Altinors, N | 1 |
| Caner, H | 1 |
| Koshi, T | 1 |
| Yamashita, M | 1 |
| Arai, G | 1 |
| De Oliveira, GS | 1 |
| Charchaflieh, J | 1 |
| Walega, D | 1 |
| Klessinger, S | 1 |
| Artner, J | 1 |
| Cakir, B | 1 |
| Reichel, H | 1 |
| Lattig, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion[NCT05461092] | Early Phase 1 | 50 participants (Anticipated) | Interventional | 2024-01-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for bupivacaine and Degenerative Disc Disease
| Article | Year |
|---|---|
Local Retropharyngeal Space Anesthetic for Dysphagia Reduction after Anterior Cervical Discectomy and Fusion Surgery: A Single-Center, Prospective, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial.
Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Cervical Vertebrae; Deglutition Disorders; Diskectomy; | 2021 |
Injection of bupivacaine into disc space to detect painful nonunion after anterior lumbar interbody fusion (ALIF) surgery in patients with discogenic low back pain.
Topics: Adolescent; Adult; Anesthetics, Local; Bupivacaine; Female; Humans; Injections, Intralesional; Inter | 2014 |
In vivo effects of bupivacaine and gadobutrol on the intervertebral disc following discoblock and discography: a histological analysis.
Topics: Adult; Anesthetics, Local; Bupivacaine; Contrast Media; Female; Humans; Injections; Intervertebral D | 2017 |
Lumbar microdiscectomy with spinal anesthesia: comparison of prone and knee-chest positions in means of hemodynamic and respiratory function.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Blood Pressure; Bupivacaine; Chi-Square Distribution; | 2010 |
Surgical versus nonsurgical treatment of selected patients with discogenic low back pain: a small-sized randomized trial.
Topics: Adult; Bupivacaine; Exercise Therapy; Female; Follow-Up Studies; Humans; Intervertebral Disc Degener | 2011 |
11 other studies available for bupivacaine and Degenerative Disc Disease
| Article | Year |
|---|---|
Intramuscular Liposomal Bupivacaine Decreases Length of Stay and Opioid Usage Following Lumbar Spinal Fusion.
Topics: Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cohort Studies; Female; Humans; Injections, Int | 2020 |
Fluoroscopic Epidural Steroid Injection: Pain Relief in Discogenic Sciatica Versus Lumbar Spinal Stenosis. A Study on Middle Eastern Patients.
Topics: Adult; Aged; Analgesia, Epidural; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Case-Co | 2020 |
Comparison of Thoracolumbar Interfascial Plane Block with the Application of Local Anesthesia in the Management of Postoperative Pain in Patients with Lumbar Disc Surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Hum | 2021 |
Endoscopic transforaminal lumbar interbody fusion without general anesthesia: operative and clinical outcomes in 100 consecutive patients with a minimum 1-year follow-up.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Disk | 2019 |
Effects of Intradiscal Injection of Local Anesthetics on Intervertebral Disc Degeneration in Rabbit Degenerated Intervertebral Disc.
Topics: Anesthetics, Local; Animals; Bupivacaine; Disease Models, Animal; Intervertebral Disc; Intervertebra | 2019 |
The impact of sagittal balance on low back pain in patients treated with zygoapophysial facet joint injection.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Drug Combinations; Female; Glucocorticoids | 2014 |
Effects of single injection of local anesthetic agents on intervertebral disc degeneration: ex vivo and long-term in vivo experimental study.
Topics: Anesthetics, Local; Animals; Bupivacaine; Injections; Intervertebral Disc Degeneration; Lidocaine; O | 2014 |
CT-guided infiltration saves surgical intervention and fastens return to work compared to anatomical landmark-guided infiltration in patients with lumbosciatica.
Topics: Adult; Analgesics; Anatomic Landmarks; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Fe | 2015 |
Pneumorrhachis mimicking meningitis after a paramedian lumbar interlaminar injection.
Topics: Aged; Back Pain; Bupivacaine; Chronic Disease; Female; Humans; Injections, Spinal; Intervertebral Di | 2011 |
Radicular pain in post lumbar surgery syndrome: the significance of transforaminal injection of steroids.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Drug Therapy, Co | 2013 |
[Injection techniques in the cervical spine].
Topics: Adrenal Cortex Hormones; Amides; Analgesics, Opioid; Anesthesia, Local; Bupivacaine; Cervical Verteb | 2012 |