Page last updated: 2024-10-23

bupivacaine and Coronary Disease

bupivacaine has been researched along with Coronary Disease in 12 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
" These eight men and two women, aged 58 +/- 5 years, with extensive three-vessel coronary disease and ejection fractions of 40% +/- 5%, had New York Heart Association (NYHA) class IV angina despite medical therapy, including nitrates, beta-blockade, calcium channel blockade, and narcotics."3.69Treatment of medically and surgically refractory angina pectoris with high thoracic epidural analgesia: initial clinical experience. ( Gramling-Babb, P; Miller, MJ; Reeves, ST; Roy, RC; Zile, MR, 1997)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's10 (83.33)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Timlin, HM1
Carnaffin, SA1
Starkey, IR1
Northridge, DB1
Leslie, SJ1
Helms, U1
Weihrauch, H1
Jacobitz, K1
Stenseth, R2
Bjella, L2
Berg, EM2
Christensen, O2
Levang, OW2
Gisvold, SE2
Mergner, GW1
Stolte, AL1
Frame, WB1
Lim, HJ1
Alam, S1
Sakura, S1
Kosaka, Y1
Gramling-Babb, P1
Miller, MJ1
Reeves, ST1
Roy, RC1
Zile, MR1
McLintic, AJ1
Pringle, SD1
Lilley, S1
Houston, AB1
Thorburn, J1
Tsuchida, H1
Omote, T1
Miyamoto, M1
Namiki, A1
Ichihara, K1
Abiko, Y1
Lessire, H1
Pfisterer, M1
Schweppe-Hartenauer, ML1
Puchstein, C1
Kock, M1
Blomberg, S2
Emanuelsson, H2
Lomsky, M1
Strömblad, SO1
Ricksten, SE2
Kvist, H1
Lamm, C1
Pontén, J1
Waagstein, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
High Thoracic Epidural Reduces Risks of Increased Left Ventricular Mass Index and Coronary Vascular Disease During Aortic Valve Replacement Alone or in Addition to Coronary Artery Bypass Graft Surgery[NCT03719248]80 participants (Actual)Interventional2017-01-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for bupivacaine and Coronary Disease

ArticleYear
Randomized, controlled study of long-acting local anesthetic (levobupivacaine) in femoral artery sheath management during and after percutaneous coronary intervention.
    The Journal of invasive cardiology, 2005, Volume: 17, Issue:8

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Angioplasty, Balloon, Coronary; Bupivacaine; Coronary D

2005
[Cardio-circulatory changes following peridural anaesthesia with and without adrenaline-containing local anaesthetics in elderly patients (author's transl)].
    Der Anaesthesist, 1980, Volume: 29, Issue:7

    Topics: Aged; Aging; Anesthesia, Epidural; Brain Ischemia; Bupivacaine; Coronary Disease; Epinephrine; Heart

1980
Thoracic epidural analgesia in aortocoronary bypass surgery. II: Effects on the endocrine metabolic response.
    Acta anaesthesiologica Scandinavica, 1994, Volume: 38, Issue:8

    Topics: Analgesia, Epidural; Anesthesia, Intravenous; Blood Glucose; Bupivacaine; Coronary Artery Bypass; Co

1994
Thoracic epidural analgesia in aortocoronary bypass surgery. I: Haemodynamic effects.
    Acta anaesthesiologica Scandinavica, 1994, Volume: 38, Issue:8

    Topics: Analgesia, Epidural; Anesthesia, Intravenous; Bupivacaine; Coronary Artery Bypass; Coronary Disease;

1994

Other Studies

8 other studies available for bupivacaine and Coronary Disease

ArticleYear
Combined epidural analgesia and general anesthesia induce ischemia distal to a severe coronary artery stenosis in swine.
    Anesthesia and analgesia, 1994, Volume: 78, Issue:1

    Topics: Anesthesia, Epidural; Anesthesia, General; Animals; Blood Pressure; Bupivacaine; Coronary Circulatio

1994
Anaesthetic management for caesarean section in a patient with Kawasaki disease.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:11

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Epidural; Anesth

1995
Treatment of medically and surgically refractory angina pectoris with high thoracic epidural analgesia: initial clinical experience.
    American heart journal, 1997, Volume: 133, Issue:6

    Topics: Adrenergic beta-Antagonists; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Anesthetics, Local

1997
Electrocardiographic changes during cesarean section under regional anesthesia.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:1

    Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Bupivacaine; Cesarean Section; Coronary Disease; Ec

1992
Effects of thoracic epidural anesthesia on myocardial pH and metabolism during ischemia.
    Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:6

    Topics: Adenosine Triphosphate; Anesthesia, Epidural; Animals; Bupivacaine; Coronary Disease; Dogs; Female;

1991
[Hemodynamic effects of a combination of general and peridural anesthesia during anesthesia induction in geriatric patients].
    Der Anaesthesist, 1991, Volume: 40, Issue:7

    Topics: Aged; Aged, 80 and over; Anesthesia, Epidural; Anesthesia, General; Bupivacaine; Coronary Disease; F

1991
Thoracic epidural anesthesia improves global and regional left ventricular function during stress-induced myocardial ischemia in patients with coronary artery disease.
    Anesthesia and analgesia, 1990, Volume: 71, Issue:6

    Topics: Aged; Analgesia, Epidural; Bupivacaine; Coronary Disease; Exercise Test; Female; Hemodynamics; Human

1990
Effects of thoracic epidural anesthesia on coronary arteries and arterioles in patients with coronary artery disease.
    Anesthesiology, 1990, Volume: 73, Issue:5

    Topics: Aged; Anesthesia, Epidural; Arteries; Arterioles; Autonomic Nerve Block; Bupivacaine; Coronary Angio

1990