Page last updated: 2024-10-23

bupivacaine and Cleft Palate

bupivacaine has been researched along with Cleft Palate in 17 studies

Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.

Cleft Palate: Congenital fissure of the soft and/or hard palate, due to faulty fusion.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the postoperative analgesia after surgical site infiltration with bupivacaine or ketamine in children undergoing cleft palate surgery."9.17A randomized study of surgical site infiltration with bupivacaine or ketamine for pain relief in children following cleft palate repair. ( Bhardwaj, N; Jha, AK; Mahajan, JK; Sharma, RK; Yaddanapudi, S, 2013)
" We evaluated the effect of adding dexmedetomidine to bupivacaine on the duration of postoperative analgesia in children who underwent repair of a cleft palate."9.14Addition of dexmedetomidine to bupivacaine for greater palatine nerve block prolongs postoperative analgesia after cleft palate repair. ( Abdelazees, M; Aboushanab, O; Ibraheem, N; Obayah, GM; Refaie, A, 2010)
"A retrospective review of cleft palate cases over a 1-year period, 6 months with hemostatic pledgets, and 6 months with bupivacaine-soaked hemostatic pledgets."7.77Does use of bupivacaine-soaked pledgets aid in the care of postoperative cleft palate patients? ( Burstein, FD; Otterburn, DM, 2011)
"To evaluate the postoperative analgesia after surgical site infiltration with bupivacaine or ketamine in children undergoing cleft palate surgery."5.17A randomized study of surgical site infiltration with bupivacaine or ketamine for pain relief in children following cleft palate repair. ( Bhardwaj, N; Jha, AK; Mahajan, JK; Sharma, RK; Yaddanapudi, S, 2013)
" We evaluated the effect of adding dexmedetomidine to bupivacaine on the duration of postoperative analgesia in children who underwent repair of a cleft palate."5.14Addition of dexmedetomidine to bupivacaine for greater palatine nerve block prolongs postoperative analgesia after cleft palate repair. ( Abdelazees, M; Aboushanab, O; Ibraheem, N; Obayah, GM; Refaie, A, 2010)
"A retrospective review of cleft palate cases over a 1-year period, 6 months with hemostatic pledgets, and 6 months with bupivacaine-soaked hemostatic pledgets."3.77Does use of bupivacaine-soaked pledgets aid in the care of postoperative cleft palate patients? ( Burstein, FD; Otterburn, DM, 2011)
"To determine whether placement of a bupivacaine-soaked absorbable sponge (BAS) in addition to bupivacaine infiltration at the anterior iliac crest (AIC) donor site alters postoperative pain for children undergoing alveolar bone grafting (ABG) for cleft lip with or without cleft palate (CL+/-P)."3.75Bupivacaine administration and postoperative pain following anterior iliac crest bone graft for alveolar cleft repair. ( Dashow, JE; Egbert, MA; Gruss, JS; Hopper, RA; Lewis, CW, 2009)
"These areas are management of postoperative pain with nonopioid oral analgesics, peripheral nerve blockade, liposomal bupivacaine for donor-site analgesia in bone grafting, and enhanced recovery after surgery (ERAS) protocols."2.72Postoperative pain management in pediatric cleft lip and palate repair. ( Flowers, T; Winters, R, 2021)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (17.65)29.6817
2010's11 (64.71)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Patel, RA1
Jablonka, EM1
Rustad, KC1
Pridgen, BC1
Sorice-Virk, SS1
Borrelli, MR1
Khosla, RK1
Lorenz, HP1
Momeni, A1
Wan, DC1
Crowley, JS1
McLean, P1
Gabriel, RA1
Cronin, B1
Hsieh, S1
Englar, K1
Said, E1
Lance, S1
Gosman, A1
Barbero, GE1
de Miguel, M2
Sierra, P2
Merritt, G2
Bora, P2
Borah, N2
Ciarallo, C2
Ing, R1
Bosenberg, A2
de Nadal, M2
Flowers, T1
Winters, R1
Day, KM1
Nair, NM1
Sargent, LA1
Echaniz, G1
Ing, RJ1
Jha, AK1
Bhardwaj, N1
Yaddanapudi, S1
Sharma, RK1
Mahajan, JK1
Kumar Raja, D1
Anantanarayanan, P1
Christabel, A1
Manikandhan, R1
Elavazhagan, N1
Naveen Kumar, J1
Isyanov, A1
Suresh, S1
Dashow, JE1
Lewis, CW1
Hopper, RA1
Gruss, JS1
Egbert, MA1
Obayah, GM1
Refaie, A1
Aboushanab, O1
Ibraheem, N1
Abdelazees, M1
Sbitany, H1
Koltz, PF1
Waldman, J1
Girotto, JA1
Fuzaylov, G1
Ying, B1
Tang, Y1
Sethna, NF1
Hayes, JA1
Forrest, CR1
Walsh, W1
Pétroz, GC1
Adeli, K1
Bissonnette, B1
Meara, DJ1
Livingston, NR1
Sittitavornwong, S1
Ness, T1
Boyce, J1
Wang, D1
Waite, PD1
Otterburn, DM1
Burstein, FD1
Bateman, MC1
Conejero, JA1
Mooney, EK1
Rothkopf, DM1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Liposomal Bupivacaine Pharmacokinetic Study After Median Sternotomy Incision Infiltration in a Pediatric Cardiac Surgery[NCT04685421]Phase 115 participants (Actual)Interventional2021-07-15Terminated (stopped due to PI, Christopher Tirotta, no longer at NCH as of 5-26-23.)
Prospective Randomized Trial of Penile Nerve Block With Liposomal Bupivacaine for Hypospadias Repair vs Standard Penile Block With Bupivacaine[NCT04479371]Phase 10 participants (Actual)Interventional2021-07-31Withdrawn (stopped due to Limited funding and resources to complete FDA requirements for enrollment)
The Effect of Dexamedetomidine for Interscalene Brachial Plexus Block on Plasma Cortisol and IL-6 After Rotator Cuff Repair: a Prospective Randomized Study[NCT02766556]50 participants (Actual)Interventional2014-08-31Completed
The Effectiveness of Bupivicaine Infusion Versus Intravenous Ketorolac for Postoperative Analgesia After Iliac Crest Bone Harvesting for Lefort I Osteotomy or Alveolar Cleft Repair.[NCT00405262]Phase 354 participants (Actual)Interventional2006-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for bupivacaine and Cleft Palate

ArticleYear
Postoperative pain management in pediatric cleft lip and palate repair.
    Current opinion in otolaryngology & head and neck surgery, 2021, Aug-01, Volume: 29, Issue:4

    Topics: Anesthetics, Local; Bupivacaine; Child; Cleft Lip; Cleft Palate; Humans; Pain, Postoperative

2021

Trials

7 trials available for bupivacaine and Cleft Palate

ArticleYear
Clonidine as an Adjuvant to Bupivacaine for Suprazygomatic Maxillary Nerve Blocks in Cleft lip and Palate Repair: A Randomized, Prospective, Double-Blind Study.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2021, Volume: 58, Issue:6

    Topics: Aged; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Cleft Lip; Cleft Palate; Clonidine;

2021
Bilateral suprazygomatic maxillary nerve blocks vs. infraorbital and palatine nerve blocks in cleft lip and palate repair: A double-blind, randomised study.
    European journal of anaesthesiology, 2019, Volume: 36, Issue:1

    Topics: Adolescent; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Cleft Lip; Cleft Palate; Doubl

2019
A randomized study of surgical site infiltration with bupivacaine or ketamine for pain relief in children following cleft palate repair.
    Paediatric anaesthesia, 2013, Volume: 23, Issue:5

    Topics: Anesthesia, Local; Anesthetics, Dissociative; Anesthetics, Local; Bupivacaine; Child; Child Behavior

2013
Donor site analgesia after anterior iliac bone grafting in paediatric population: a prospective, triple-blind, randomized clinical trial.
    International journal of oral and maxillofacial surgery, 2014, Volume: 43, Issue:4

    Topics: Alveolar Ridge Augmentation; Anesthetics, Local; Bupivacaine; Catheters, Indwelling; Child; Cleft Pa

2014
Addition of dexmedetomidine to bupivacaine for greater palatine nerve block prolongs postoperative analgesia after cleft palate repair.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:3

    Topics: Bupivacaine; Cleft Palate; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Infant; Male;

2010
Continuous bupivacaine infusion post-iliac crest bone graft harvesting in pediatric cleft surgery: role and comparison with ketorolac.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2011, Volume: 48, Issue:5

    Topics: Adolescent; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bone Tr

2011
Continuous infusion of bupivacaine for pain control after anterior iliac crest bone grafting for alveolar cleft repair in children.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2011, Volume: 48, Issue:6

    Topics: Adolescent; Alveolar Process; Anesthetics, Local; Bone Transplantation; Bupivacaine; Child; Child, P

2011

Other Studies

9 other studies available for bupivacaine and Cleft Palate

ArticleYear
Retrospective cohort-based comparison of intraoperative liposomal bupivacaine versus bupivacaine for donor site iliac crest analgesia during alveolar bone grafting.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2019, Volume: 72, Issue:12

    Topics: Administration, Topical; Alveolar Bone Grafting; Analgesia; Anesthetics, Local; Bupivacaine; Child;

2019
The Association of Liposomal Bupivacaine on Opioid Consumption in the Pediatric Alveolar Cleft Population.
    The Journal of craniofacial surgery, 2020, Volume: 31, Issue:4

    Topics: Adolescent; Alveolar Bone Grafting; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child; Clef

2020
Extended Release Liposomal Bupivacaine Injection (Exparel) for Early Postoperative Pain Control Following Palatoplasty.
    The Journal of craniofacial surgery, 2018, Volume: 29, Issue:5

    Topics: Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cleft Palate; Delayed-Action Preparations; Ente

2018
Continuous ilioinguinal nerve catheter infusions for iliac bone graft: postoperative pain control without adverse effects!
    Paediatric anaesthesia, 2009, Volume: 19, Issue:3

    Topics: Anesthetics, Local; Bupivacaine; Catheterization; Child; Cleft Lip; Cleft Palate; Female; Humans; Il

2009
Bupivacaine administration and postoperative pain following anterior iliac crest bone graft for alveolar cleft repair.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2009, Volume: 46, Issue:2

    Topics: Alveoloplasty; Anesthetics, Local; Bone Transplantation; Bupivacaine; Child; Cleft Lip; Cleft Palate

2009
Continuous bupivacaine infusion in iliac bone graft donor sites to minimize pain and hospitalization.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2010, Volume: 47, Issue:3

    Topics: Alveolar Ridge Augmentation; Anesthetics, Local; Bone Transplantation; Bupivacaine; Cleft Lip; Cleft

2010
Successful resuscitation after inadvertent intravenous injection of bupivacaine in an adolescent.
    Paediatric anaesthesia, 2010, Volume: 20, Issue:10

    Topics: Adolescent; Anesthetics, Local; Bupivacaine; Cardiopulmonary Resuscitation; Cleft Lip; Cleft Palate;

2010
Does use of bupivacaine-soaked pledgets aid in the care of postoperative cleft palate patients?
    Annals of plastic surgery, 2011, Volume: 66, Issue:5

    Topics: Acetaminophen; Administration, Topical; Anesthetics, Local; Bone Transplantation; Bupivacaine; Case-

2011
Short-stay cleft palate surgery with intraoperative dexamethasone and marcaine.
    Annals of plastic surgery, 2006, Volume: 57, Issue:3

    Topics: Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Cleft Palate; Dexamethasone; Glucocorticoi

2006